DNA methylome analysis of human peripheral blood samples in cancer discordant monozygotic twin-pairs

Dataset

Description

Accession Number: GSE89093

Platform:
GPL13534: Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)

Organism: Homo sapiens

Published on 2016-10-25

Summary:
Genome wide DNA methylation profiling with the HumanMethylation450 BeadChip (450k) of peripheral blood samples of 46 adult female monozygotic twin-pairs obtained at the same time point. Samples included 41 healthy females (not diagnosed with cancer to date) paired with their co-twin diagnosed with cancer within a 5 year window around the time of sampling as well as 5 extra pairs with a co-twin diagnosed with cancer within 11 to 5 years prior to blood sampling.

Overall Design:
Bisulphite converted DNA from the 92 samples were hybridised to the Illumina HumanMethylation450 BeadChip

Contact:
Name: Tim Spector
Organization: King's College London
Deparment: Twin Research and Genetic Epidemiology
Address: Westminster Bridge road London United Kingdom
Email: tim.spector@kcl.ac.uk

Organization: Illumina Inc.
Address: 9885 Towne Centre Drive San Diego CA 92121 USA
Email: expression@illumina.com, techsupport@illumina.com
Phone: 1 800 809 4566
Web-Link: www.illumina.com
Date made available25 Oct 2016
PublisherGene Expression Omnibus

Cite this