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Cancer Chemotherapy and Pharmacology, 0344-5704

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  1. A phase I study to assess afatinib in combination with carboplatin or with carboplatin plus paclitaxel in patients with advanced solid tumors

    O’Brien, M. E. R., Sarker, D., Bhosle, J., Thillai, K., Yap, T. A., Uttenreuther-Fischer, M., Pemberton, K., Jin, X., Wiebe, S., De Bono, J. & Spicer, J., 7 Aug 2018, In : Cancer Chemotherapy and Pharmacology.

    Research output: Contribution to journalArticle

  2. Genetic variability in the regulation of the expression cluster of MDR genes in patients with breast cancer

    Tsyganov, M. M., Freidin, M. B., Ibragimova, M. K., Deryusheva, I. V., Kazantseva, P. V., Slonimskaya, E. M., Cherdyntseva, N. V. & Litviakov, N. V., Aug 2017, In : Cancer Chemotherapy and Pharmacology. 80, 2, p. 251-260 10 p.

    Research output: Contribution to journalArticle

  3. A phase I study of afatinib combined with paclitaxel and bevacizumab in patients with advanced solid tumors

    Spicer, J., Irshad, S., Ang, J. E., Enting, D., Kristeleit, R., Uttenreuther-Fischer, M., Pemberton, K., Pelling, K., Schnell, D. & de Bono, J., Jan 2017, In : Cancer Chemotherapy and Pharmacology. 79, 1, p. 17-27 11 p.

    Research output: Contribution to journalArticle

  4. Olaparib tablet formulation: effect of food on the pharmacokinetics after oral dosing in patients with advanced solid tumours

    Plummer, R., Swaisland, H., Leunen, K., van Herpen, C. M. L., Jerusalem, G., De Grève, J., Lolkema, M. P., Soetekouw, P., Mau-Sørensen, M., Nielsen, D., Spicer, J., Fielding, A., So, K., Bannister, W. & Molife, L. R., Oct 2015, In : Cancer Chemotherapy and Pharmacology. 76, 4, p. 723-9 7 p.

    Research output: Contribution to journalArticle

  5. Phase II, open-label trial to assess QTcF effects, pharmacokinetics and antitumor activity of afatinib in patients with relapsed or refractory solid tumors

    Molife, L. R., Rudman, S. M., Alam, S., Tan, D. S. -W., Kristeleit, H., Middleton, G., Propper, D., Bent, L., Stopfer, P., Uttenreuther-Fischer, M., Wallenstein, G., de Bono, J. & Spicer, J., Dec 2013, In : Cancer Chemotherapy and Pharmacology. 72, 6, p. 1213-1222 10 p.

    Research output: Contribution to journalArticle

  6. Phase I evaluation of the effects of ketoconazole and rifampicin on cediranib pharmacokinetics in patients with solid tumours

    Lassen, U., Miller, W. H., Hotte, S., Evans, T. R. J., Kollmansberger, C., Adamson, D., Nielsen, D. L., Spicer, J., Chen, E., Meyer, T., Brown, K., Rafi, R. & Sawyer, M. B., Feb 2013, In : Cancer Chemotherapy and Pharmacology. 71, 2, p. 543-549 7 p., N/A.

    Research output: Contribution to journalArticle

  7. A two-part Phase II study of cediranib in patients with advanced solid tumours: the effect of food on single-dose pharmacokinetics and an evaluation of safety, efficacy and imaging pharmacodynamics

    Mitchell, C. L., O'Connor, J. P. B., Roberts, C., Watson, Y., Jackson, A., Cheung, S., Evans, J., Spicer, J., Harris, A., Kelly, C., Rudman, S., Middleton, M., Fielding, A., Tessier, J., Young, H., Parker, G. J. M. & Jayson, G. C., Sep 2011, In : Cancer Chemotherapy and Pharmacology. 68, 3, p. 631 - 641 11 p.

    Research output: Contribution to journalArticle

  8. Pharmacokinetics, pharmacodynamics and metabolism of the dimeric pyrrolobenzodiazepine SJG-136 in rats

    Reid, JM., Buhrow, SA., Kuffel, MJ., Jia, L., Spanswick, VJ., Hartley, JA., Thurston, DE., Tomaszewski, JE. & Ames, MM., Sep 2011, In : Cancer Chemotherapy and Pharmacology. 68, 3, p. 777 - 786 10 p.

    Research output: Contribution to journalArticle

  9. The contribution of deleterious DPYD gene sequence variants to fluoropyrimidine toxicity in British cancer patients

    Loganayagam, A., Arenas-Hernandez, M., Fairbanks, L., Ross, P., Sanderson, J. D. & Marinaki, A. M., Jan 2010, In : Cancer Chemotherapy and Pharmacology. 65, 2, p. 403-406 4 p.

    Research output: Contribution to journalArticle

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