King's College London

Research portal

Intensive Care Medicine, ‎0342-4642

Journal

  1. Effect of oral chlorhexidine de-adoption and implementation of an oral care bundle on mortality for mechanically ventilated patients in the intensive care unit (CHORAL): a multi-center stepped wedge cluster-randomized controlled trial

    Dale, C. M., Rose, L., Carbone, S., Pinto, R., Smith, O. M., Burry, L., Fan, E., Amaral, A. C. K. B., McCredie, V. A., Scales, D. C. & Cuthbertson, B. H., Nov 2021, In: Intensive Care Medicine. 47, 11, p. 1295-1302 8 p.

    Research output: Contribution to journalArticlepeer-review

  2. The REMDACTA trial: do interleukin receptor antagonists provide additional benefit in COVID-19?

    Tatham, K. C., Shankar-Hari, M. & Arabi, Y. M., Nov 2021, In: Intensive Care Medicine. 47, 11, p. 1315-1318 4 p.

    Research output: Contribution to journalEditorialpeer-review

  3. Delirium in COVID-19: can we make the unknowns knowns?

    Wilcox, M. E., Shankar-Hari, M. & McAuley, D. F., Oct 2021, In: Intensive Care Medicine. 47, 10, p. 1144-1147 4 p.

    Research output: Contribution to journalArticlepeer-review

  4. Pharmacological and non-pharmacological interventions to prevent delirium in critically ill patients: a systematic review and network meta-analysis

    Burry, L. D., Cheng, W., Williamson, D. R., Adhikari, N. K., Egerod, I., Kanji, S., Martin, C. M., Hutton, B. & Rose, L., Sep 2021, In: Intensive Care Medicine. 47, 9, p. 943-960 18 p.

    Research output: Contribution to journalReview articlepeer-review

  5. Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial

    REMAP-CAP Investigators, 4 Aug 2021, In: Intensive Care Medicine. 47, 8, p. 867-886 20 p.

    Research output: Contribution to journalArticlepeer-review

  6. Acute kidney injury in the critically ill: an updated review on pathophysiology and management

    Pickkers, P., Darmon, M., Hoste, E., Joannidis, M., Legrand, M., Ostermann, M., Prowle, J. R., Schneider, A. & Schetz, M., Aug 2021, In: Intensive Care Medicine. 47, 8, p. 835-850 16 p.

    Research output: Contribution to journalReview articlepeer-review

  7. Effect of oral chlorhexidine de-adoption and implementation of an oral care bundle on mortality for mechanically ventilated patients in the intensive care unit: A multi-centered stepped wedge cluster randomized controlled trial.

    Dale, C. M., Rose, L., Carbone, S., Smith, O. M., Burry, L., Fan, E., Amaral, A. C., McCredie, V. A., Scales, D. C. & Cuthbertson, B. H., 5 Jul 2021, (Accepted/In press) In: Intensive Care Medicine.

    Research output: Contribution to journalArticlepeer-review

  8. Restrictive fluid management versus usual care in acute kidney injury (REVERSE-AKI): a pilot randomized controlled feasibility trial

    on behalf of the REVERSE-AKI study team, Jun 2021, In: Intensive Care Medicine. 47, 6, p. 665-673 9 p.

    Research output: Contribution to journalArticlepeer-review

  9. Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

    on behalf of the DecubICUs Study Team & the European Society of Intensive Care Medicine (ESICM) Trials Group Collaborators, Feb 2021, In: Intensive Care Medicine. 47, 2, p. 160–169 10 p.

    Research output: Contribution to journalArticlepeer-review

  10. COVID-19 in critical care: epidemiology of the first epidemic wave across England, Wales and Northern Ireland

    ICNARC COVID-19 Team, 1 Nov 2020, In: Intensive Care Medicine. 46, 11, p. 2035-2047 13 p.

    Research output: Contribution to journalArticlepeer-review

  11. Neuromuscular blockade in patients with ARDS: a rapid practice guideline

    Alhazzani, W., Belley-Cote, E., Møller, M. H., Angus, D. C., Papazian, L., Arabi, Y. M., Citerio, G., Connolly, B., Denehy, L., Fox-Robichaud, A., Hough, C. L., Laake, J. H., Machado, F. R., Ostermann, M., Piraino, T., Sharif, S., Szczeklik, W., Young, P. J., Gouskos, A., Kiedrowski, K. & 1 others, Burns, K. E. A., 1 Nov 2020, In: Intensive Care Medicine. 46, 11, p. 1977-1986 10 p.

    Research output: Contribution to journalReview articlepeer-review

  12. Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA study

    DIANA study group, 1 Jul 2020, In: Intensive Care Medicine. 46, 7, p. 1404-1417 14 p.

    Research output: Contribution to journalArticlepeer-review

  13. Identification and validation of biomarkers of persistent acute kidney injury: the RUBY study

    the RUBY Investigators, 1 May 2020, In: Intensive Care Medicine. 46, 5, p. 943-953 11 p.

    Research output: Contribution to journalArticlepeer-review

  14. Rate and risk factors for rehospitalisation in sepsis survivors: systematic review and meta-analysis

    Shankar-Hari, M., Saha, R., Wilson, J., Prescott, H. C., Harrison, D., Rowan, K., Rubenfeld, G. D. & Adhikari, N. K. J., 1 Apr 2020, In: Intensive Care Medicine. 46, 4, p. 619-636 18 p.

    Research output: Contribution to journalReview articlepeer-review

  15. Could stress ulcer prophylaxis increase mortality in high-acuity patients?

    Harhay, M. O., Young, P. J. & Shankar-Hari, M., 19 Feb 2020, (E-pub ahead of print) In: Intensive Care Medicine. 46, 4, p. 793-795 3 p.

    Research output: Contribution to journalEditorialpeer-review

  16. Should we consider blocking the inhibitory immune checkpoint molecules for treating T cell exhaustion in sepsis?

    Shankar-Hari, M., Fish, M. & Azoulay, E., 1 Jan 2020, In: Intensive Care Medicine. 46, 1, p. 119-121 3 p.

    Research output: Contribution to journalEditorialpeer-review

  17. Trials on oxygen supplementation in sepsis: better late than never

    Perner, A., De Jong, A. & Shankar-Hari, M., 1 Jan 2020, In: Intensive Care Medicine. 46, 1, p. 116-118 3 p.

    Research output: Contribution to journalEditorialpeer-review

  18. Less is more: ten reasons for considering to discontinue unproven interventions

    Darmon, M., Benoit, D. D. & Ostermann, M., 1 Nov 2019, In: Intensive Care Medicine. 45, 11, p. 1626-1628 3 p.

    Research output: Contribution to journalArticlepeer-review

  19. Focus on sepsis

    Møller, M. H., Alhazzani, W. & Shankar-Hari, M., 1 Oct 2019, In: Intensive Care Medicine. 45, 10, p. 1459-1461 3 p.

    Research output: Contribution to journalEditorialpeer-review

  20. How to feed a patient with acute kidney injury

    Ostermann, M., Macedo, E. & Oudemans-van Straaten, H., 1 Jul 2019, In: Intensive Care Medicine. 45, 7, p. 1006-1008 3 p.

    Research output: Contribution to journalComment/debatepeer-review

  21. Changes in critically ill cancer patients’ short-term outcome over the last decades: results of systematic review with meta-analysis on individual data

    Darmon, M., Bourmaud, A., Georges, Q., Soares, M., Jeon, K., Oeyen, S., Rhee, C. K., Gruber, P., Ostermann, M., Hill, Q. A., Depuydt, P., Ferra, C., Toffart, A. C., Schellongowski, P., Müller, A., Lemiale, V., Mokart, D. & Azoulay, E., Jul 2019, In: Intensive Care Medicine. 45, 7, p. 977-987 11 p.

    Research output: Contribution to journalReview articlepeer-review

  22. Whole genome sequencing reveals that genetic conditions are frequent in intensively ill children

    Next Generation Children Project, French, C. E., Delon, I., Dolling, H., Sanchis-Juan, A., Shamardina, O., Mégy, K., Abbs, S., Austin, T., Bowdin, S., Branco, R. G., Firth, H., NIHR BioResource—Rare Disease Consortium, Williamson, C., Rowitch, D. H., Raymond, F. L. & Dixon, P., May 2019, In: Intensive Care Medicine. 45, 5, p. 627-636 10 p.

    Research output: Contribution to journalArticlepeer-review

  23. Lung–kidney interactions in critically ill patients: consensus report of the Acute Disease Quality Initiative (ADQI) 21 Workgroup

    Joannidis, M., Forni, L. G., Klein, S. J., Honore, P. M., Kashani, K., Ostermann, M., Prowle, J., Bagshaw, S. M., Cantaluppi, V., Darmon, M., Ding, X., Fuhrmann, V., Hoste, E., Husain-Syed, F., Lubnow, M., Maggiorini, M., Meersch, M., Murray, P. T., Ricci, Z., Singbartl, K. & 4 others, Staudinger, T., Welte, T., Ronco, C. & Kellum, J. A., 1 Jan 2019, In: Intensive Care Medicine.

    Research output: Contribution to journalArticlepeer-review

  24. Acute Respiratory Distress Syndrome (ARDS) Phenotyping

    Shankar-Hari, M., Fan, E. & Ferguson, N., 5 Dec 2018, (E-pub ahead of print) In: Intensive Care Medicine.

    Research output: Contribution to journalArticlepeer-review

  25. Early PREdiction of sepsis using leukocyte surface biomarkers: the ExPRES-sepsis cohort study

    Shankar-Hari, M., Datta, D., Wilson, J., Assi, V., Stephen, J., Weir, C. J., Rennie, J., Antonelli, J., Bateman, A., Felton, J. M., Warner, N., Judge, K., Keenan, J., Wang, A., Burpee, T., Brown, A. K., Lewis, S. M., Mare, T., Roy, A. I., Wright, J. & 7 others, Hulme, G., Dimmick, I., Gray, A., Rossi, A. G., Simpson, A. J., Morris, A. C. & Walsh, T. S., 5 Oct 2018, (E-pub ahead of print) In: Intensive Care Medicine. p. 1-13 13 p.

    Research output: Contribution to journalArticlepeer-review

  26. Prevalence and risk factors related to haloperidol use for delirium in adult intensive care patients: the multinational AID-ICU inception cohort study

    Collet, M. O., Caballero, J., Sonneville, R., Bozza, F. A., Nydahl, P., Schandl, A., Wøien, H., Citerio, G., van Den Boogaard, M., Hästbacka, J., Haenggi, M., Colpaert, K., Rose, L., Barbateskovic, M., Lange, T., Jensen, A., Krog, M. B., Egerod, I., Nibro, H. L., Wetterslev, J. & 1 others, Perner, A., Jul 2018, In: Intensive Care Medicine. 9 p.

    Research output: Contribution to journalArticlepeer-review

  27. Cell-surface signatures of immune dysfunction risk-stratify critically ill patients: INFECT study

    Morris, A. C., Datta, D., Shankar-Hari, M., Stephen, J., Weir, C. J., Rennie, J., Antonelli, J., Bateman, A., Warner, N., Judge, K., Keenan, J., Wang, A., Burpee, T., Brown, K. A., Lewis, S. M., Mare, T., Roy, A. I., Hulme, G., Dimmick, I., Rossi, A. G. & 2 others, Simpson, A. J. & Walsh, T. S., 11 Jun 2018, (E-pub ahead of print) In: Intensive Care Medicine. 9 p.

    Research output: Contribution to journalArticlepeer-review

  28. Efficacy and safety of trimodulin, a novel polyclonal antibody preparation, in patients with severe community-acquired pneumonia: a randomized, placebo-controlled, double-blind, multicenter, phase II trial (CIGMA study)

    Welte, T., Dellinger, P., Ebelt, H., Ferrer, M., Opal, S., Singer, M., Vincent, J-L., Werdan, K., Martin‐Loeches, I., Almirall, J., Artigas, A., Ignacio Ayestarán, J., Nuding, S., Ferrer, R., Sirgo Rodríguez, G., Shankar-Hari, M., Álvarez‐Lerma, F., Riessen, R., Sirvent, JM., Kluge, S. & 23 others, Zacharowski, K., Bonastre Mora, J., Lapp, H., Wöbker, G., Achtzehn, U., Brealey, D., Kempa, A., Sánchez García, M., Brederlau, J., Kochanek, M., Peer Reschreiter, H., Wise, M., Belohradsky, B., Bobenhausen, I., Dälken, B., Dubovy, P., Langohr, P., Mayer, M., Schüttrumpf, J., Wartenberg‐Demand, A., Wippermann, U., Wolf, D. & Torres, A., 9 Apr 2018, (E-pub ahead of print) In: Intensive Care Medicine.

    Research output: Contribution to journalArticlepeer-review

  29. Immunoglobulins and Sepsis

    Shankar-Hari, M., Bruun Madsen, M. & Turgeon, A., 18 Jan 2018, (E-pub ahead of print) In: Intensive Care Medicine.

    Research output: Contribution to journalArticlepeer-review

  30. Physical restraint: time to let go

    Burry, L., Rose, L. & Ricou, B., Nov 2017, In: Intensive Care Medicine. p. 1-3 3 p.

    Research output: Contribution to journalArticlepeer-review

  31. The intensive care medicine research agenda on septic shock

    Perner, A., Gordon, A. C., Angus, D. C., Lamontagne, F., Machado, F., Russell, J. A., Timsit, J-F., Marshall, J. C., Myburgh, J., Shankar-Hari, M. & Singer, M., Sep 2017, In: Intensive Care Medicine. 43, 9, p. 1294–1305

    Research output: Contribution to journalArticlepeer-review

  32. The intensive care delirium research agenda: a multinational, interprofessional perspective

    Pandharipande, P. P., Ely, E. W., Arora, R. C., Balas, M. C., Boustani, M. A., La Calle, G. H., Cunningham, C., Devlin, J. W., Elefante, J., Han, J. H., MacLullich, A. M., Maldonado, J. R., Morandi, A., Needham, D. M., Page, V. J., Rose, L., Salluh, J. I. F., Sharshar, T., Shehabi, Y., Skrobik, Y. & 2 others, Slooter, A. J. C. & Smith, H. A. B., 13 Jun 2017, (E-pub ahead of print) In: Intensive Care Medicine. 43, 9, p. 1329-1339 11 p.

    Research output: Contribution to journalArticlepeer-review

  33. The AKI glossary

    Schneider, A. & Ostermann, M., Jun 2017, In: Intensive Care Medicine. p. 893-897 5 p.

    Research output: Contribution to journalArticlepeer-review

  34. Early enteral nutrition in critically ill patients: ESICM clinical practice guidelines

    Reintam Blaser, A., Starkopf, J., Alhazzani, W., Berger, M. M., Casaer, M. P., Deane, A. M., Fruhwald, S., Hiesmayr, M., Ichai, C., Jakob, S. M., Loudet, C. I., Malbrain, M. L. N. G., Montejo González, J. C., Paugam-Burtz, C., Poeze, M., Preiser, J. C., Singer, P., van Zanten, A. R. H., De Waele, J., Wendon, J. & 4 others, Wernerman, J., Whitehouse, T., Wilmer, A. & Oudemans-van Straaten, H. M., 1 Mar 2017, In: Intensive Care Medicine. 43, 3, p. 380-398 19 p.

    Research output: Contribution to journalReview articlepeer-review

  35. Do we have adequate tools and skills to manage uncertainty among patients and families in ICU?

    Harding, R., Hopkins, P., Metaxa, V. & Higginson, I. J., Mar 2017, In: Intensive Care Medicine. 43, 4, p. 463–464

    Research output: Contribution to journalLetterpeer-review

  36. Statins in patients with sepsis and ARDS: is it over? No

    Kruger, P. S. & Terblanche, M., 17 Oct 2016, (E-pub ahead of print) In: Intensive Care Medicine.

    Research output: Contribution to journalEditorialpeer-review

  37. Pediatric extubation readiness tests should not use pressure support

    Khemani, R. G., Hotz, J., Morzov, R., Flink, R. C., Kamerkar, A., LaFortune, M., Rafferty, G. F., Ross, P. A. & Newth, C. J. L., 1 Aug 2016, In: Intensive Care Medicine. 42, 8, p. 1214-1222 9 p.

    Research output: Contribution to journalArticlepeer-review

  38. LiFe: a liver injury score to predict outcome in critically ill patients

    Edmark, C., McPhail, M. J. W., Bell, M., Whitehouse, T., Wendon, J. & Christopher, K. B., Mar 2016, In: Intensive Care Medicine. 42, 3, p. 361-369 9 p.

    Research output: Contribution to journalArticlepeer-review

  39. Endogenous IgG hypogammaglobulinaemia in critically ill adults with sepsis: systematic review and meta-analysis

    Shankar-Hari, M., Culshaw, N., Post, B., Tamayo, E., Andaluz-Ojeda, D., Bermejo-Martín, J. F., Dietz, S., Werdan, K., Beale, R., Spencer, J. & Singer, M., 14 May 2015, In: Intensive Care Medicine. 41, 8, p. 1393-1401 9 p.

    Research output: Contribution to journalArticlepeer-review

  40. Do we need a new definition of sepsis?

    Shankar-Hari, M., Deutschman, C. S. & Singer, M., 3 Feb 2015, In: Intensive Care Medicine. 41, 5, p. 909-911 3 p.

    Research output: Contribution to journalEditorialpeer-review

  41. What’s new in acute liver failure?

    Bernsmeier, C., Antoniades, C. G. & Wendon, J., 26 Sep 2014, In: Intensive Care Medicine. 40, 10, p. 1545-1548 4 p.

    Research output: Contribution to journalArticlepeer-review

  42. EARLY PLASMA EXCHANGE ALLEVIATES PRO-INFLAMMATORY CYTOKINE SECRETION OF PERIPHERAL MONOCYTES IN PATIENTS WITH ACUTE LIVER FAILURE

    Bernsmeier, C., Patel, V. C., Singanayagam, A., Willars, C., Bernal, W., Auzinger, G., Antoniades, C. G. & Wendon, J., Sep 2014, In: Intensive Care Medicine. 40, p. S30-S30 1 p.

    Research output: Contribution to journalMeeting abstractpeer-review

  43. FREE IMMUNOGLOBULIN LIGHT CHAIN CONCENTRATIONS, RATIOS ANT) OUTCOMES IN CRITICALLY ILL ADULTS WITH SEPSIS: A COHORT STUDY

    Shankar-Hari, M., Assi, L., Beale, R., Spencer, J. & Singer, M., Sep 2014, In: Intensive Care Medicine. 40, p. S87-S88 2 p.

    Research output: Contribution to journalMeeting abstractpeer-review

  44. HEALTHCARE ASSOCIATED BLOOD STREAM INFECTIONS IN CRITICALLY ILL PATIENTS: DESCRIPTIVE CROSS-SECTIONAL DATABASE STUDY EVALUATING CONCORDANCE WITH CLINICAL SITE INFECTIONS

    Culshaw, N., Glover, G., Whiteley, C., Wyncoll, D., Jones, A. & Shankar-Hari, M., Sep 2014, In: Intensive Care Medicine. 40, p. S144-S144 1 p.

    Research output: Contribution to journalMeeting abstractpeer-review

  45. IMMUNOGTOBUTLN G CONCENTRATIONS AND OUTCOMES CRITICALLY ILL ADULTS WITH SEPSIS: A SYSTEMATIC REVIEW ES IN CRITICALLY

    Culshaw, N., Post, B., Beale, R., Spencer, J., Singer, M. & Shankar-Hari, M., Sep 2014, In: Intensive Care Medicine. 40, p. S151-S151 1 p.

    Research output: Contribution to journalMeeting abstractpeer-review

  46. MECHANICAL VENTILATION PRACTICES IN PATIENTS WITH ARDS RECEIVING ECMO: AN INTERNATIONAL SURVEY

    Camporota, L., Nicoletti, E., Malafronte, M., de Neer, M., Mongelli, V., Calderazzo, M. A., Caricola, E. V., Glover, G., Meadows, C., Beale, R., Shankar-Hari, M. & Barrett, N., Sep 2014, In: Intensive Care Medicine. 40, p. S186-S186 1 p.

    Research output: Contribution to journalMeeting abstractpeer-review

  47. RELATIONSHIP BETWEEN SERUM TYPE III PRO-COLLAGEN PEPTIDE AND ECMO DURATION IN SEVERE RESPIRATORY FAILURE

    Camporota, L., Calderazzo, M. A., Mongelli, V., Caricola, E. V., Glover, G., Meadows, C., Nicoletti, E., Malafronte, M., Beale, R., Shankar-Hari, M. & Barrett, N., Sep 2014, In: Intensive Care Medicine. 40, p. S232-S232 1 p.

    Research output: Contribution to journalMeeting abstractpeer-review

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