King's College London

Research portal

Molecular therapy : the journal of the American Society of Gene Therapy, ‎1525-0016

Journal

  1. VEGF-B Gene Therapy for the Heart: Proceed with Caution

    Giacca, M. & Recchia, F. A., 8 Jul 2020, In: Molecular Therapy. 28, 7, p. 1566-1568 3 p.

    Research output: Contribution to journalArticlepeer-review

  2. Non-invasive Reporter Gene Imaging of Cell Therapies, including T Cells and Stem Cells

    Ashmore-Harris, C., Iafrate, M., Saleem, A. & Fruhwirth, G. O., 3 Jun 2020, In: Molecular Therapy. 28, 6, p. 1392-1416 25 p., 10.1016/j.ymthe.2020.03.016.

    Research output: Contribution to journalReview articlepeer-review

  3. Gene Therapy for Glaucoma by Ciliary Body Aquaporin 1 Disruption Using CRISPR-Cas9

    Wu, J., Bell, O. H., Copland, D. A., Young, A., Pooley, J. R., Maswood, R., Evans, R. S., Khaw, P. T., Ali, R. R., Dick, A. D. & Chu, C. J., 4 Mar 2020, In: Molecular Therapy. 28, 3, p. 820-829 10 p.

    Research output: Contribution to journalArticlepeer-review

  4. A Stem Cell-Based Screening Platform Identifies Compounds that Desensitize Motor Neurons to Endoplasmic Reticulum Stress

    Thams, S., Lowry, E. R., Larraufie, M. H., Spiller, K. J., Li, H., Williams, D. J., Hoang, P., Jiang, E., Williams, L. A., Sandoe, J., Eggan, K., Lieberam, I., Kanning, K. C., Stockwell, B. R., Henderson, C. E. & Wichterle, H., 2 Jan 2019, In: Molecular Therapy. 27, 1, p. 87-101 15 p.

    Research output: Contribution to journalArticlepeer-review

  5. Development of Targeted siRNA Nanocomplexes to Prevent Fibrosis in Experimental Glaucoma Filtration Surgery

    Fernando, O., Tagalakis, A. D., Awwad, S., Brocchini, S., Khaw, P. T., Hart, S. L. & Yu-Wai-Man, C., 5 Dec 2018, In: Molecular Therapy. 26, 12, p. 2812-2822 11 p.

    Research output: Contribution to journalArticlepeer-review

  6. Molecular Recalibration of PD-1+ Antigen-Specific T Cells from Blood and Liver

    Otano, I., Escors, D., Schurich, A., Singh, H., Robertson, F., Davidson, B. R., Fusai, G., Vargas, F. A., Tan, Z. M. D., Aw, J. Y. J., Hansi, N., Kennedy, P. T. F., Xue, S-A., Stauss, H. J., Bertoletti, A., Pavesi, A. & Maini, M. K., 7 Nov 2018, In: Molecular therapy : the journal of the American Society of Gene Therapy. 26, 11, p. 2553-2566

    Research output: Contribution to journalArticlepeer-review

  7. Prevention of Photoreceptor Cell Loss in a Cln6nclf Mouse Model of Batten Disease Requires CLN6 Gene Transfer to Bipolar Cells

    Kleine Holthaus, S-M., Ribeiro, J., Abelleira-Hervas, L., Pearson, R. A., Duran, Y., Georgiadis, A., Sampson, R. D., Rizzi, M., Hoke, J., Maswood, R., Azam, S., Luhmann, U. F. O., Smith, A. J., Mole, S. E. & Ali, R. R., 2 May 2018, In: Molecular therapy : the journal of the American Society of Gene Therapy. 26, 5, p. 1343-1353 11 p.

    Research output: Contribution to journalArticlepeer-review

  8. MicroRNA-21 and the Vulnerability of Atherosclerotic Plaques

    Barwari, T., Rienks, M. & Mayr, M., 21 Mar 2018, (E-pub ahead of print) In: Molecular Therapy.

    Research output: Contribution to journalArticlepeer-review

  9. Therapeutic Delivery of miR-148a Suppresses Ventricular Dilation in Heart Failure

    Raso, A., Dirkx, E., Philippen, L. E., Fernandez-Celis, A., De Majo, F., Sampaio-Pinto, V., Sansonetti, M., Juni, R., el Azzouzi, H., Calore, M., Bitsch, N., Olieslagers, S., Oerlemans, M. I. F. J., Huibers, M. M., de Weger, R. A., Reckman, Y. J., Pinto, Y. M., Zentilin, L., Zacchigna, S., Giacca, M. & 3 others, da Costa Martins, P. A., López-Andrés, N. & De Windt, L. J., 1 Jan 2018, (Accepted/In press) In: Molecular Therapy.

    Research output: Contribution to journalArticlepeer-review

  10. Low-Dose Nitric Oxide as Targeted Anti-biofilm Adjunctive Therapy to Treat Chronic Pseudomonas aeruginosa Infection in Cystic Fibrosis

    Howlin, R. P., Cathie, K., Hall-Stoodley, L., Cornelius, V., Duignan, C., Allan, R. N., Fernandez, B. O., Barraud, N., Bruce, K. D., Jefferies, J., Kelso, M., Kjelleberg, S., Rice, S. A., Rogers, G. B., Pink, S., Smith, C., Sukhtankar, P. S., Salib, R., Legg, J., Carroll, M. & 7 others, Daniels, T., Feelisch, M., Stoodley, P., Clarke, S. C., Connett, G., Faust, S. N. & Webb, J. S., 6 Sep 2017, In: Molecular Therapy. 25, 9, p. 2104-2116 13 p.

    Research output: Contribution to journalArticlepeer-review

  11. Targeting of aberrant αvβ6 integrin expression in solid tumors using chimeric antigen receptor-engineered T-cells

    Whilding, L. M., Parente Pereira, A. C., Zabinski, T., Davies, D. M., Petrovic, R., Kao, V., Saxena, S. A., Romain, A., Costa-Guerra, J. A., Violette, S., Itamochi, H., Ghaem-Maghami, S., Vallath, S., Marshall, J. F. & Maher, J., 4 Jan 2017, In: Molecular Therapy. 25, 1, p. 259-273

    Research output: Contribution to journalArticlepeer-review

  12. Rapid and Efficient Stable Gene Transfer to Mesenchymal Stromal Cells Using a Modified Foamy Virus Vector

    Sweeney, N. P., Regan, C., Liu, J., Galleu, A., Dazzi, F., Lindemann, D., Rupar, C. A. & McClure, M. O., 2 May 2016, In: Molecular Therapy. 24, 7, p. 1227-1236 10 p.

    Research output: Contribution to journalArticlepeer-review

  13. Suppression of IL-7-dependent Effector T-cell Expansion by Multipotent Adult Progenitor Cells and PGE2

    Reading, J. L., Vaes, B., Hull, C., Sabbah, S., Hayday, T., Wang, N. S., DiPiero, A., Lehman, N. A., Taggart, J. M., Carty, F., English, K., Pinxteren, J., Deans, R., Ting, A. E. & Tree, T. I. M., 1 Nov 2015, In: Molecular Therapy. 23, 11, p. 1783-1793

    Research output: Contribution to journalArticlepeer-review

  14. RNA mimics as therapeutics for cardiac regeneration: A paradigm shift

    Giacca, M., 1 Jun 2015, In: Molecular Therapy. 23, 6, p. 984-986 3 p.

    Research output: Contribution to journalComment/debatepeer-review

  15. Proliferation of multiple cell types in the skeletal muscle tissue elicited by acute p21 suppression

    Biferi, M. G., Nicoletti, C., Falcone, G., Puggioni, E. M. R., Passaro, N., Mazzola, A., Pajalunga, D., Zaccagnini, G., Rizzuto, E., Auricchio, A., Zentilin, L., De Luca, G., Giacca, M., Martelli, F., Musio, A., Musarò, A. & Crescenzi, M., 9 May 2015, In: Molecular Therapy. 23, 5, p. 885-895 11 p.

    Research output: Contribution to journalArticlepeer-review

  16. Genetically engineered human islets protected from CD8-mediated autoimmune destruction in vivo

    Zaldumbide, A., Alkemade, G., Carlotti, F., Nikolic, T., Abreu, J. R., Engelse, M. A., Skowera, A., de Koning, E. J., Peakman, M., Roep, B. O., Hoeben, R. C. & Wiertz, E. J., Aug 2013, In: Molecular therapy : the journal of the American Society of Gene Therapy. 21, 8, p. 1592-1601 10 p.

    Research output: Contribution to journalArticlepeer-review

  17. The β-globin locus control region in combination with the EF1α short promoter allows enhanced lentiviral vector-mediated erythroid gene expression with conserved multilineage activity

    Montiel-Equihua, C. A., Zhang, L., Knight, S., Saadeh, H., Scholz, S., Carmo, M., Alonso-Ferrero, M. E., Blundell, M. P., Monkeviciute, A., Schulz, R., Collins, M., Takeuchi, Y., Schmidt, M., Fairbanks, L., Antoniou, M., Thrasher, A. J. & Gaspar, H. B., Jul 2012, In: Molecular Therapy. 20, 7, p. 1400-1409 10 p.

    Research output: Contribution to journalArticlepeer-review

  18. AAV-Mediated Targeted Gene Addition in Patient-Specific SCID-X1 Induced Pluripotent Stem Cells

    Bardelli, M., Zhang, F., Linden, R. M., Thrasher, A. J. & Henckaerts, E., May 2012, In: Molecular Therapy. 20, p. S152-S152 1 p.

    Research output: Contribution to journalMeeting abstractpeer-review

  19. Terminal differentiation of cardiac and skeletal myocytes induces permissivity to AAV transduction by relieving inhibition imposed by DNA damage response proteins

    Lovric, J., Mano, M., Zentilin, L., Eulalio, A., Zacchigna, S. & Giacca, M., 1 Jan 2012, In: Molecular Therapy. 20, 11, p. 2087-2097 11 p.

    Research output: Contribution to journalArticlepeer-review

  20. Insulin-producing surrogate β-cells from embryonic stem cells: are we there yet?

    Naujok, O., Burns, C., Jones, P. M. & Lenzen, S., Oct 2011, In: Molecular therapy : the journal of the American Society of Gene Therapy. 19, 10, p. 1759-1768 10 p.

    Research output: Contribution to journalArticlepeer-review

  21. Perturbing PSD-95 Interactions With NR2B-subtype Receptors Attenuates Spinal Nociceptive Plasticity and Neuropathic Pain

    D'Mello, R., Marchand, F., Pezet, S., McMahon, S. B. & Dickenson, A. H., Oct 2011, In: Molecular Therapy. 19, 10, p. 1780-1792 13 p.

    Research output: Contribution to journalArticlepeer-review

  22. Heartening results: The CUPID gene therapy trial for heart failure

    Giacca, M. & Baker, A. H., 1 Jul 2011, In: Molecular Therapy. 19, 7, p. 1181-1182 2 p.

    Research output: Contribution to journalEditorialpeer-review

  23. Stem Cell Gene Therapy for Fanconi Anemia: Report from the 1st International Fanconi Anemia Gene Therapy Working Group Meeting

    Tolar, J., Adair, J. E., Antoniou, M., Bartholomae, C. C., Becker, P. S., Blazar, B. R., Bueren, J., Carroll, T., Cavazzana-Calvo, M., Clapp, D. W., Dalgleish, R., Galy, A., Gaspar, H. B., Hanenberg, H., Von Kalle, C., Kiem, H-P., Lindeman, D., Naldini, L., Navarro, S., Renella, R. & 7 others, Rio, P., Sevilla, J., Schmidt, M., Verhoeyen, E., Wagner, J. E., Williams, D. A. & Thrasher, A. J., Jul 2011, In: Molecular Therapy. 19, 7, p. 1193 - 1198 6 p.

    Research output: Contribution to journalLiterature reviewpeer-review

  24. Lentiviral vector integration profiles differ in rodent postmitotic tissues

    Bartholomae, C. C., Arens, A., Balaggan, K. S., Yá̃ez-Mũoz, R. J., Montini, E., Howe, S. J., Paruzynski, A., Korn, B., Appelt, J. U., MacNeil, A., Cesana, D., Abel, U., Glimm, H., Naldini, L., Ali, R. R., Thrasher, A. J., Von Kalle, C. & Schmidt, M., Apr 2011, In: Molecular Therapy. 19, 4, p. 703-710 8 p.

    Research output: Contribution to journalArticlepeer-review

  25. A Ubiquitous Chromatin Opening Element (UCOE) Confers Resistance to DNA Methylation-mediated Silencing of Lentiviral Vectors

    Zhang, F., Frost, A. R., Blundell, M. P., Bales, O., Antoniou, M. N. & Thrasher, A. J., Sep 2010, In: Molecular Therapy. 18, 9, p. 1640 - 1649 10 p.

    Research output: Contribution to journalArticlepeer-review

  26. Desmin-regulated Lentiviral Vectors for Skeletal Muscle Gene Transfer

    Talbot, G. E., Waddington, S. N., Bales, O., Tchen, R. C. & Antoniou, M. N., Mar 2010, In: Molecular Therapy. 18, 3, p. 601 - 608 8 p.

    Research output: Contribution to journalArticlepeer-review

  27. Molecular Therapy 18, 2139-2145. Lentivirus-mediated reprogramming of somatic cells in the absence of transgenic transcription factors

    Kane, NM., Nowrouzi, A., Mukherjee, S., Blundell, MP., Grieg, JA., Lee, WK., Houslay, MD., Milligan, G., Mountford, JC., Von Kalle, C., Schmidt, M., Thrasher, AJ. & Baker, AH., 2010, In: Molecular Therapy. 18, p. 2139 - 2145 7 p.

    Research output: Contribution to journalArticlepeer-review

  28. Characterization of Spinal Cord Transduction by Integration-Deficient Lentiviral Vectors

    Peluffo, H., Foster, E., Ahmed, S. G. O., Moon, L., Hutson, T., Yip, P., Wanisch, K., McMahon, S. B. & Yanez-Munoz, R. J., 2009, In: Molecular Therapy. 17, p. S198 - S199

    Research output: Contribution to journalMeeting abstract

  29. Delivery of Therapeutic Proteins as Secretable TAT Fusion Products

    Flinterman, M., Farzaneh, F., Habib, N., Malik, F., Gaken, J. & Tavassoli, M., 2009, In: Molecular Therapy. 17, 2, p. 334 - 342 9 p.

    Research output: Contribution to journalArticlepeer-review

  30. Fetal Gene Therapy for Acute Neuronopathic Gaucher Disease

    Rahim, A. A., Wong, A. M., Buckley, S. M., Hughes, D. A., Karlsson, S., Cooper, J. D., Thrasher, A. J., Mehta, A. & Waddington, S. N., 2009, In: Molecular Therapy. 17, p. S357 - S357

    Research output: Contribution to journalMeeting abstract

  31. Lentiviral Gene Therapy Strategies for the Nuclear Protein Aggregation Disorder Oculopharyngeal Muscular Dystrophy (OPMD)

    Bales, O., Trollet, C., van der Maarel, S., Dickson, G. & Antoniou, M. N., 2009, In: Molecular Therapy. 17, p. S363 - S363

    Research output: Contribution to journalMeeting abstract

  32. Ubiquitous Chromatin Opening Element (UCOE)-Driven Transgenes within Lentiviral Vectors Are Not Subject to DNA Methylation Mediated Silencing

    Zhang, F., Antoniou, M. N. & Thrasher, A. J., 2009, In: Molecular Therapy. 17, p. S161 - S161

    Research output: Contribution to journalMeeting abstract

  33. Improvement of migratory defects in a murine model of Wiskott-Aldrich syndrome gene therapy

    Blundell, M. P., Bouma, G., Calle, Y., Jones, G. E., Kinnon, C. & Thrasher, A. J., May 2008, In: Molecular Therapy. 16, 5, p. 836 - 844 9 p.

    Research output: Contribution to journalArticlepeer-review

  34. Intraventricular enzyme replacement improves disease phenotypes in a mouse model of late infantile neuronal ceroid lipofuscinosis

    Chang, M., Cooper, J. D., Sleat, D. E., Cheng, S. H., Dodge, J. C., Passini, M. A., Lobel, P. & Davidson, B. L., Apr 2008, In: Molecular Therapy. 16, 4, p. 649 - 656 8 p.

    Research output: Contribution to journalArticlepeer-review

  35. Gene transfer of an engineered zinc finger protein enhances the anti-angiogenic defense system

    Yokoi, K., Zhang, H. S., Kachi, S., Balaggan, K. S., Yu, Q., Guschin, D., Kunis, M., Surosky, R., Africa, L. M., Bainbridge, J. W., Spratt, S. K., Gregory, P. D., Ali, R. R. & Campochiaro, P. A., Nov 2007, In: Molecular Therapy. 15, 11, p. 1917-1923 7 p.

    Research output: Contribution to journalArticlepeer-review

  36. Hsp40 molecules that target to the ubiquitin-proteasome system decrease inclusion formation in models of polyglutamine disease

    Howarth, J. L., Kelly, S., Keasey, M. P., Glover, C. P. J., Lee, Y-B., Mitrophanous, K., Chapple, J. P., Gallo, J. M., Cheetham, M. E., Uney, J. B. & Lee, Y., Jun 2007, In: Molecular therapy : the journal of the American Society of Gene Therapy. 15, 6, p. 1100 - 1105 6 p.

    Research output: Contribution to journalArticlepeer-review

  37. Recent advances and current challenges in tumor immunology and immunotherapy

    Guinn, B. A., Kasahara, N., Farzaneh, F., Habib, N. A., Norris, J. S. & Deisseroth, A. B., Jun 2007, In: Molecular Therapy. 15, 6, p. 1065 - 1071 7 p.

    Research output: Contribution to journalLiterature reviewpeer-review

  38. Gene therapy for beta-thalassemia: studies on human cells.

    Roselli, EA., Cesari, R., Miccio, A., Tiboni, F., Corbella, P., Rossi, C., Biral, E., Marktel, S., Antoniou, M., Andreani, M., Lucarelli, G. & Ferrari, G., 2007, In: Molecular Therapy. 15, p. S249 - S249 651.

    Research output: Contribution to journalPoster abstract

  39. Integration-deficient lentiviral vectors mediate efficient gene transfer to nervous system and muscle.

    Yanez-Munoz, RJ., Foster, E., Yip, P., McMahon, SB., Waddington, S. & Antoniou, M., 2007, In: Molecular Therapy. 15, p. S378 - S378 989.

    Research output: Contribution to journalPoster abstract

  40. Lentiviral-transduced HSC lead to long-term correction of beta-thalassemia by in vivo selection or erythroid progenitors.

    Miccio, A., Cesari, R., Rossi, C., Tiboni, F., Sanvito, F., Ponzoni, M., Routledge, S., Antoniou, M. & Ferrari, G., 2007, In: Molecular Therapy. 15, p. S96 - S96 250.

    Research output: Contribution to journalPoster abstract

  41. In Contrast to AAV-Mediated Cntf Expression, AAV-Mediated Gdnf Expression Enhances Gene Replacement Therapy in Rodent Models of Retinal Degeneration

    Buch, P. K., MacLaren, R. E., Durán, Y., Balaggan, K. S., MacNeil, A., Schlichtenbrede, F. C., Smith, A. J. & Ali, R. R., Nov 2006, In: Molecular Therapy. 14, 5, p. 700-709 10 p.

    Research output: Contribution to journalArticlepeer-review

  42. Involvement of sphingolipids in apoptin-induced cell killing

    Liu, X., Zeidan, Y. H., Elojeimy, S., Holman, D. H., El-Zawahry, A. M., Guo, G. W., Bielawska, A., Bielawski, J., Szulc, Z., Rubinchik, S., Dong, J. Y., Keane, T. E., Tavassoli, M., Hannun, Y. A. & Norris, J. S., Nov 2006, In: Molecular Therapy. 14, 5, p. 627 - 636 10 p.

    Research output: Contribution to journalArticlepeer-review

  43. Modulation of ceramide metabolism enhances viral protein Apoptin's cytotoxicity in prostate cancer

    Liu, X., Elojeimy, S., El-Zawahry, A. M., Holman, D. H., Bielawska, A., Bielawski, J., Rubinchik, S., Guo, G. W., Dong, J. Y., Keane, T., Hannun, Y. A., Tavassoli, M. & Norris, J. S., Nov 2006, In: Molecular Therapy. 14, 5, p. 637 - 646 10 p.

    Research output: Contribution to journalArticlepeer-review

  44. Cytoglobin overexpression protects against damage-induced fibrosis

    Xu, R., Harrison, P. M., Chen, M., Li, L. Y., Tsui, T. Y., Fung, P. C. W., Cheung, P. T., Wang, G. J., Li, H., Diao, Y., Krissansen, G. W., Xu, S. & Farzaneh, F., Jun 2006, In: Molecular Therapy. 13, 6, p. 1093 - 1100 8 p.

    Research output: Contribution to journalArticlepeer-review

  45. Reversal of neurochemical changes and pain-related behavior in a model of neuropathic pain using modified lentiviral vectors expressing GDNF

    Pezet, S., Krzyzanowska, A., Wong, L. F., Grist, J., Mazarakis, N. D., Georgievska, B. & McMahon, S. B., Jun 2006, In: Molecular Therapy. 13, 6, p. 1101 - 1109 9 p.

    Research output: Contribution to journalArticlepeer-review

  46. Erratum: "Local administration of an adeno-associated viral vector expressing IL-10 reduces monocyte infiltration and subsequent photoreceptor damage during experimental autoimmune uveitis" (Molecular Therapy (2005) vol. 12 (369-373) 10.1016/j.ymthe.2005.03.018)

    Broderick, C. A., Smith, A. J., Balaggan, K. S., Georgiadis, A., Buch, P. K., Trittibach, P. C., Barker, S. E., Sarra, G. M., Thrasher, A. J., Dick, A. D. & Ali, R. R., Apr 2006, In: Molecular Therapy. 13, 4, p. 829 1 p.

    Research output: Contribution to journalComment/debatepeer-review

  47. Metabolic biotinylation of lentiviral pseudotypes for scalable paramagnetic microparticle-dependent manipulation

    Nesbeth, D., Williams, S. L., Chan, L., Brain, T., Slater, N. K. H., Farzaneh, F. & Darling, D., Apr 2006, In: Molecular Therapy. 13, 4, p. 814 - 822 9 p.

    Research output: Contribution to journalArticlepeer-review

Previous 1 2 Next

View graph of relations

© 2020 King's College London | Strand | London WC2R 2LS | England | United Kingdom | Tel +44 (0)20 7836 5454