King's College London

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Osteoarthritis and Cartilage, ‎1063-4584

Journal

  1. Intra-articular injection of triamcinolone acetonide in a sustained release polyesteramide formulation shows prolonged anti-inflammatory efficacy in a rat model

    Jansen, I., Woike, N., De Jong, S., Versteeg, S., Kik, M., Emans, P., Mihov, G., Thies, J. C., Eijkelkamp, N., Tryfonidou, M. A. & Creemers, L. B., 1 Apr 2019, In: Osteoarthritis and Cartilage. 27, p. S418-S419

    Research output: Contribution to journalArticlepeer-review

  2. Controlled release of celecoxib inhibits inflammation and subchondral bone changes in a rat model of osteoarthritis

    Tellegen, A. R., Jansen, I., Pouran, B., De Visser, H., Thomas, R. E., Kik, M. J., Grinwis, G. C., Thies, J. C., Woike, N., Mihov, G., Emans, P. J., Meij, B. P., Creemers, L. B. & Tryfonidou, M. A., 1 Apr 2018, In: Osteoarthritis and Cartilage. 26, p. S72

    Research output: Contribution to journalArticlepeer-review

  3. Intradiscal delivery of celecoxib-loaded microspheres restores disc homeostasis in a preclinical canine model of intervertebral disc degeneration

    Tellegen, A. R., Jansen, I., Beukers, M., Miranda-bedate, A., De Jong, W., Woike, N., Thies, J. C., Mihov, G., Meij, B. P., Creemers, L. B. & Tryfonidou, M. A., 1 Apr 2018, In: Osteoarthritis and Cartilage. 26, p. S418-S419

    Research output: Contribution to journalArticlepeer-review

  4. Novel sustained releasing triamcinolone acetonide polyesteramide microparticle platfform to reduce pain in the knee of a synoviatis rat model

    Woike, N., Jansen, I., Tellegen, A., Creemers, L., Tryfonidou, M., Mihov, G., Thies, J. C., Schrijver, K., Versteeg, S. & Eijkelkamp, N., 1 Apr 2018, In: Osteoarthritis and Cartilage. 26, p. S119

    Research output: Contribution to journalArticlepeer-review

  5. Implementing core nice guidelines for osteoarthritis in primary care with a model consultation (MOSAICS): A cluster randomised controlled trial

    Dziedzic, K. S., Healey, E. L., Porcheret, M., Afolabi, E. K., Lewis, M., Morden, A., Jinks, C., McHugh, G. A., Ryan, S., Finney, A., Main, C., Edwards, J. J., Paskins, Z., Pushpa-Rajah, A. & Hay, E. M., 14 Oct 2017, (E-pub ahead of print) In: Osteoarthritis and Cartilage.

    Research output: Contribution to journalArticlepeer-review

  6. Role of TrkA signalling and mast cells in the initiation of osteoarthritis pain in the monoiodoacetate model

    De Sousa Valente, J., Calvo, L., Vacca, V., Simeoli, R., Arévalo, J. C. & Malcangio, M., 24 Aug 2017, (E-pub ahead of print) In: Osteoarthritis and Cartilage.

    Research output: Contribution to journalArticlepeer-review

  7. Hydroxychloroquine in hand OA; Results of the UK hero trial: Abstracts from the 2017 OARSI World Congress on Osteoarthritis

    Kingsbury, S. R., Tharmanathan, P., Keding, A., Ronaldson, S., Grainger, A., Wakefield, R., Arundel, C., Birrell, F., Doherty, M., Vincent, T., Watt, F. E., Dziedzic, K., O'Neill, T., Arden, N., Scott, D. L., Dickson, J., Garrood, T., Green, M., Menon, A., Sheeran, T. & 2 others, Torgerson, D. & Conaghan, P. G., Apr 2017, In: Osteoarthritis and Cartilage. 25, Supplement 1, p. S3-S4

    Research output: Contribution to journalMeeting abstractpeer-review

  8. Large scale meta-analysis of urinary C-terminal telopeptide, serum cartilage oligomeric protein and matrix metalloprotease degraded type II collagen and their role in prevalence, incidence and progression of osteoarthritis

    Valdes, A. M., Meulenbelt, I., Chassaing, E., Arden, N. K., Bierma-Zeinstra, S., Harat, D., Hofman, A., Karsdal, M., Kloppenburg, M., Kroon, H. M., Slagboom, E. P., Spector, T. D., Uitterlinden, A. G., van Meurs, J. B. & Bay-Jensen, A. C., May 2014, In: Osteoarthritis and Cartilage. 22, 5, p. 683-689 7 p.

    Research output: Contribution to journalArticlepeer-review

  9. Human genetic studies on osteoarthritis from clinicians' viewpoints Reply

    Kerkhof, H. J. M., Evangelou, E., Meulenbelt, I., van Meurs, J. B. J., Zeggini, E. & Valdes, A. M., Mar 2012, In: Osteoarthritis and Cartilage. 20, 3, p. 250 - 251 2 p.

    Research output: Contribution to journalLetterpeer-review

  10. Methodologic issues in clinical trials for prevention or risk reduction in osteoarthritis

    Jordan, J. M., Sowers, M. F., Messier, S. P., Bradley, J., Arangio, G., Katz, J. N., Losina, E., Rovati, L., Bachtell, N., Cooper, C., Spector, T., Zhang, W., Gardiner, J. & Wahba, M., May 2011, In: Osteoarthritis and Cartilage. 19, 5, p. 500 - 508 9 p.

    Research output: Contribution to journalArticlepeer-review

  11. Large-scale meta-analysis of interleukin-1 beta and interleukin-1 receptor antagonist polymorphisms on risk of radiographic hip and knee osteoarthritis and severity of knee osteoarthritis

    Kerkhof, H. J. M., Doherty, M., Arden, N. K., Abramson, S. B., Attur, M., Bos, S. D., Cooper, C., Dennison, E. M., Doherty, S. A., Evangelou, E., Hart, D. J., Hofman, A., Javaid, K., Kerna, I., Kisand, K., Kloppenburg, M., Krasnokutsky, S., Maciewicz, R. A., Meulenbelt, I., Muir, K. R. & 14 others, Rivadeneira, F., Samuels, J., Sezgin, M., Slagboom, E., Smith, A. J. P., Spector, T. D., Tamm, A., Tamm, A., Uitterlinden, A. G., Wheeler, M., Zhai, G., Zhang, W., van Meurs, J. B. J. & Valdes, A. M., Mar 2011, In: Osteoarthritis and Cartilage. 19, 3, p. 265 - 271 7 p.

    Research output: Contribution to journalArticlepeer-review

  12. Recommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: the TREAT-OA consortium

    Kerkhof, H. J. M., Meulenbelt, I., Akune, T., Arden, N. K., Aromaa, A., Bierma-Zeinstra, S. M. A., Carr, A., Cooper, C., Dai, J., Doherty, M., Doherty, S. A., Felson, D., Gonzalez, A., Gordon, A., Harilainen, A., Hart, D. J., Hauksson, V. B., Heliovaara, M., Hofman, A., Ikegawa, S. & 30 others, Ingvarsson, T., Jiang, Q., Jonsson, H., Jonsdottir, I., Kawaguchi, H., Kloppenburg, M., Kujala, U. M., Lane, N. E., Leino-Arjas, P., Lohmander, L. S., Luyten, F. P., Malizos, K. N., Nakajima, M., Nevitt, M. C., Pols, H. A. P., Rivadeneira, F., Shi, D., Slagboom, E., Spector, T. D., Stefansson, K., Sudo, A., Tamm, A., Tamm, A. E., Tsezou, A., Uchida, A., Uitterlinden, A. G., Wilkinson, J. M., Yoshimura, N., Valdes, A. M. & van Meurs, J. B. J., Mar 2011, In: Osteoarthritis and Cartilage. 19, 3, p. 254 - 264 11 p.

    Research output: Contribution to journalArticlepeer-review

  13. Involvement of the CLEC3B gene in osteoarthritis

    Valdes, A. M., Feb 2011, In: Osteoarthritis and Cartilage. 19, 2, p. 249 - 249 1 p.

    Research output: Contribution to journalLetterpeer-review

  14. Psychological factors and their relation to osteoarthritis pain

    Wise, B. L., Niu, J., Zhang, Y., Wang, N., Jordan, J. M., Choy, E. & Hunter, D. J., Jul 2010, In: Osteoarthritis and Cartilage. 18, 7, p. 883 - 887 5 p.

    Research output: Contribution to journalArticlepeer-review

  15. A meta-analysis of interleukin-6 promoter polymorphisms on risk of hip and knee osteoarthritis

    Valdes, A. M., Arden, N. K., Tamm, A., Kisand, K., Doherty, S., Pola, E., Cooper, C., Tamm, A., Muir, K. R., Kerna, I., Hart, D., O'Neil, F., Zhang, W., Spector, T. D., Maciewicz, R. A. & Doherty, M., May 2010, In: Osteoarthritis and Cartilage. 18, 5, p. 699 - 704 6 p.

    Research output: Contribution to journalArticlepeer-review

  16. ASSOCIATION OF INTERLEUKIN-1 RECEPTOR ANTAGONIST (IL-1RN) TTG HAPLOTYPE WITH RADIOGRAPHIC KNEE OA SEVERITY IN META-ANALYSIS

    Attur, M., Kerkhof, H., Oh, C., Krasnokutsky, S., Samuels, J., Uitterlinden, A. G., Hofman, A., Rivadeneira, F., Valdes, A., Spector, T. D., van Meurs, J. & Abramson, S. B., 2010, In: Osteoarthritis and Cartilage. 18, p. S172 - S172

    Research output: Contribution to journalMeeting abstract

  17. HAS THE GWAS BEEN SUCCESSFUL?

    Spector, T. D., 2010, In: Osteoarthritis and Cartilage. 18, p. S6 - S6

    Research output: Contribution to journalMeeting abstract

  18. LARGE SCALE META-ANALYSIS OF INTERLEUKIN-1 BETA AND INTERLEUKIN-1 RECEPTOR ANTAGONIST POLYMORPHISMS ON RISK OF RADIOGRAPHIC HIP AND KNEE OSTEOARTHRITIS AND SEVERITY OF KNEE OSTEOARTHRITIS

    Kerkhof, H. J., Doherty, M., Abramson, S. B., Arden, N. K., Attur, M., Bos, S., Cooper, C., Doherty, S. A., Evangelou, E., Kerna, I., Kisand, K., Kloppenburg, M., Maciewicz, R. A., Meulenbelt, I., Sezgin, M., Slagboom, E., Smith, A., Spector, T. D., Tamm, A., Tamm, A. & 5 others, Uitterlinden, A. G., Wheeler, M., Zhang, W., van Meurs, J. B. & Valdes, A. M., 2010, In: Osteoarthritis and Cartilage. 18, p. S166 - S166

    Research output: Contribution to journalMeeting abstract

  19. LUMBAR DISC DEGENERATION AND GENETIC FACTORS ARE THE MAIN RISK FACTORS FOR LOW BACK PAIN: THE UK TWIN SPINE STUDY

    Livshits, G., Ermakov, S., Popham, M., MacGregor, A. J., Sambrook, P. N., Spector, T. D. & Williams, F. M., 2010, In: Osteoarthritis and Cartilage. 18, p. S42 - S42

    Research output: Contribution to journalMeeting abstract

  20. META-ANALYSIS OF GENOME-WIDE ASSOCIATION DATA IMPLICATES THE 4P15.3 REGION TO INFLUENCE CHRONIC WIDESPREAD PAIN IN WOMEN

    Peters, M. J., Van Wingerden, S. H., Popham, M., Kerkhof, H. J., Stolk, L., Rivadeira, F., van Duijn, C. M., Hofman, A., Williams, F. M., Uitterlinden, A. G. & van Meurs, J. B., 2010, In: Osteoarthritis and Cartilage. 18, p. S165 - S166

    Research output: Contribution to journalMeeting abstract

  21. RECOMMENDATIONS FOR STANDARDIZATION AND PHENOTYPE DEFINITIONS IN GENETIC STUDIES OF OSTEOARTHRITIS: THE TREAT-OA CONSORTIUM

    Kerkhof, H. J., Meulenbelt, I., Arden, N., Cooper, C., Doherty, M., Felson, D., Gonzalez, A., Ikegawa, S., Jiang, Q., Jonsdottir, I., Kujala, U., Lane, N., Leino-Arjas, P., Lohmander, S., Luyten, F., Nevitt, M., Slagboom, E., Spector, T., Stefansson, K., Tamm, A. & 5 others, Tsezou, A., Wilkinson, J., Yoshimura, N., Valdes, A. & van Meurs, J., 2010, In: Osteoarthritis and Cartilage. 18, p. S160 - S160

    Research output: Contribution to journalMeeting abstract

  22. STATISTICAL GENETIC ANALYSES OF LARGE JOINT OA

    Valdes, A. M., 2010, In: Osteoarthritis and Cartilage. 18, p. S5 - S5

    Research output: Contribution to journalMeeting abstract

  23. THE arcOGEN CONSORTIUM: STAGE 1 OF A GENOME-WIDE ASSOCIATION SCAN FOR OSTEOARTHRITIS

    Panoutsopoulou, K., Southam, L., Rayner, W., Zhai, G., Beazley, C., Arden, N., Carr, A., Chapman, K., Deloukas, P., Doherty, M., McCaskie, A., Olher, W., Ralston, S., Spector, T., Valdes, A., Wallis, G., Wilkinson, M., Arden, E., Battley, K., Blackburn, H. & 46 others, Blanco, F., Bumpstead, S., Cupples, A., Day-Williams, A., Dixon, K., Dohertys, S., Elliott, K., Evangelou, E., Felson, D., Gomez-Reino, J., Gonzalez, A., Gordon, A., Gwilliam, R., Hofman, A., Hunt, S., Ioannidis, J., Jonsdottir, I., Keen, R., Kerkhof, H., Kloppenburg, M., Koller, N., Lakenberg, N., Lane, N., Lee, A., Meulenbelt, I., Nevitt, M., O'Neill, F., Parimi, N., Potter, S., Rego-Perez, I., Riancho, J., Sherburn, K., Slagboom, E., Styrkarsdottir, U., Sumillera, M., Swift, D., Tsezou, A., Uitterlinden, A., van Meurs, J., Watkins, B., Wheeler, M., Mitchelle, S., Zhu, Y., Zmuda, J., Zeggini, E. & Loughlin, J., 2010, In: Osteoarthritis and Cartilage. 18, p. S166 - S167

    Research output: Contribution to journalMeeting abstract

  24. OARSI-OMERACT definition of relevant radiological progression in hip/knee osteoarthritis

    Ornetti, P., Brandt, K., Hellio-Le Graverand, M. -P., Hochberg, M., Hunter, D. J., Kloppenburg, M., Lane, N., Maillefert, J. -F., Mazzuca, S. A., Spector, T., Utard-Wlerick, G., Vignon, E. & Dougados, M., Jul 2009, In: Osteoarthritis and Cartilage. 17, 7, p. 856 - 863 8 p.

    Research output: Contribution to journalArticlepeer-review

  25. Association of a nsSNP in ADAMTS14 to some osteoarthritis phenotypes

    Rodriguez-Lopez, J., Pombo-Suarez, M., Loughlin, J., Tsezou, A., Blanco, F. J., Meulenbelt, I., Slagboom, P. E., Valdes, A. M., Spector, T. D., Gomez-Reino, J. J. & Gonzalez, A., Mar 2009, In: Osteoarthritis and Cartilage. 17, 3, p. 321 - 327 7 p.

    Research output: Contribution to journalArticlepeer-review

  26. Radiographic osteoarthritis at three joint sites and FRZB, LRP5, and LRP6 polymorphisms in two population-based cohorts

    Kerkhof, J. M., Uitterlinden, A. G., Valdes, A. M., Hart, D. J., Rivadeneira, F., Jhamai, M., Hofman, A., Pols, H. A. P., Bierma-Zeinstra, S. M. A., Spector, T. D. & van Meurs, J. B., Oct 2008, In: Osteoarthritis and Cartilage. 16, 10, p. 1141 - 1149 9 p.

    Research output: Contribution to journalArticlepeer-review

  27. A genome-wide association study reveals a novel locus for hand osteoarthritis

    Zhai, G., van Meurs, JB., Valdes, AM., Hart, D., Livshits, G., Inouye, M., Soranzo, N., Deloukas, P., Uitterlinden, A. & Spector, TD., 2008, In: Osteoarthritis and Cartilage. 16, p. S31 - S31

    Research output: Contribution to journalMeeting abstract

  28. Osteoprotegerin (OPG) gene variants and the incidence of knee osteoarthritis in the Chingford study.

    Zhang, F., Valdes, A., Hart, DJ., Uitterlinden, A., Zhai, GJ. & Spector, TD., 2008, In: Osteoarthritis and Cartilage. 16, p. S158 - S158

    Research output: Contribution to journalPoster abstract

  29. Site and gender specificity of 8 candidate genes is osteoarthritis of the hip: a study of 780 cases and 672 controls

    Valdes, AM., Doherty, M., Wheeler, M., Doherty, S. & Spector, TD., 2008, In: Osteoarthritis and Cartilage. 16, p. S155 - S155

    Research output: Contribution to journalPoster abstract

  30. Variation at the ANP32A and WMT5A genes - both involved in Wnt signaling - is associated with risk of hip osteoarthritis in women

    Valdes, AM., Hart, D., Spector, T., Zhang, F., Lories, R., Luyten, L., Pastinen, T., Uitterlinden, A., van Meurs, J., Kerkhoff, J., Doherty, S. & Doherty, M., 2008, In: Osteoarthritis and Cartilage. 16, p. S35 - S35

    Research output: Contribution to journalMeeting abstract

  31. Association between KLOTHO gene and hand osteoarthritis in a female Caucasian population

    Zhang, F., Zhai, G., Kato, B. S., Hart, D. J., Hunter, D., Spector, T. D. & Ahmadi, K. R., Jun 2007, In: Osteoarthritis and Cartilage. 15, 6, p. 624 - 629 6 p.

    Research output: Contribution to journalArticlepeer-review

  32. Genetic influence on the progression of radiographic knee osteoarthritis: a longitudinal twin study.

    Zhai, G., Hart, DJ., Kato, BS., McGregor, A. & Spector, TD., Feb 2007, In: Osteoarthritis and Cartilage. 15, 2, p. 222 - 225 4 p.

    Research output: Contribution to journalArticlepeer-review

  33. Osteophytes, juxta-articular radiolucencies and cancellous bone changes in the proximal tibia of patients with knee osteoarthritis

    Messent, E. A., Ward, R. J., Tonkin, C. J. & Buckland-Wright, C., Feb 2007, In: Osteoarthritis and Cartilage. 15, 2, p. 179 - 186 8 p.

    Research output: Contribution to journalArticlepeer-review

  34. Differences in trabecular structure between knees with and without osteoarthritis quantified by macro and standard radiography, respectively

    Messent, E. A., Ward, R. J., Tonkin, C. J. & Buckland-Wright, C., Dec 2006, In: Osteoarthritis and Cartilage. 14, 12, p. 1302 - 1305 4 p.

    Research output: Contribution to journalArticlepeer-review

  35. Design and conduct of clinical trials in patients with osteoarthritis of the hand: recommendations from a task force of the Osteoarthritis Research Society International.

    Maheu, E., Altman, R. D., Bloch, D. A., Doherty, M., Hochberg, M., Mannoni, A., Punzi, L., Spector, T., Verbruggen, G., Carr, A., Cicuttini, F., Dreiser, R. L., Haraoui, B. P., Hart, D., Pelletier, J. P., Ramonda, R. & Rovati, L., Apr 2006, In: Osteoarthritis and Cartilage. 14, 4, p. 303 - 322 20 p.

    Research output: Contribution to journalArticlepeer-review

  36. Comparison of fixed flexion, fluoroscopic semi-flexed and MTP radiographic methods for obtaining the minimum medial joint space width of the knee in longitudinal osteoarthritis trials.

    Cline, G. A., Meyer, J. M., Stevens, R., Buckland-Wright, J., Peterfy, C. & Beary, J. F., 2006, In: Osteoarthritis and Cartilage. 14, SUPPL. 1, p. 32 - 36 5 p.

    Research output: Contribution to journalArticlepeer-review

  37. Cancellous bone changes in hip osteoarthritis: a short-term longitudinal study using fractal signature analysis

    Papaloucas, C. D., Ward, R. J., Tonkin, C. J. & Buckland-Wright, C., Nov 2005, In: Osteoarthritis and Cartilage. 13, 11, p. 998 - 1003 6 p.

    Research output: Contribution to journalArticlepeer-review

  38. Relationships between tibial rim alignment and joint space width measurement reproducibility in non-fluoroscopic radiographs of osteoarthritic knees

    Ward, R. J., Buckland-Wright, J. C. & Wolfe, F., Nov 2005, In: Osteoarthritis and Cartilage. 13, 11, p. 945 - 952 8 p.

    Research output: Contribution to journalArticlepeer-review

  39. Haplotypes of the low-density lipoprotein receptor-related protein 5 (LRP5) gene: Are they a risk factor in osteoarthritis?

    Smith, A. J. P., Gidley, J., Sandy, J. R., Perry, M. J., Elson, C. J., Kirwan, J. R., Spector, T. D., Doherty, M., Bidwell, J. L. & Mansell, J. P., Jul 2005, In: Osteoarthritis and Cartilage. 13, 7, p. 608 - 613 6 p.

    Research output: Contribution to journalArticlepeer-review

  40. Tibial cancellous bone changes in patients with knee osteoarthritis. A short-term longitudinal study using Fractal Signature Analysis

    Messent, E. A., Ward, R. J., Tonkin, C. J. & Buckland-Wright, C., Jun 2005, In: Osteoarthritis and Cartilage. 13, 6, p. 463 - 470 8 p.

    Research output: Contribution to journalArticlepeer-review

  41. Measurement of structural progression in osteoarthritis of the hip: the Barcelona consensus group.

    Altman, RD., Bloch, DA., Dougados, M., Hochberg, M., Lohmander, S., Pavelka, K., Spector, TD. & Vignon, E., Jul 2004, In: Osteoarthritis and Cartilage. 12, 7, p. 515 - 524 10 p.

    Research output: Contribution to journalArticlepeer-review

  42. Hemochromatosis HFE mutations in osteoarthritis of the hand and knee

    Ross, J. M., Surdulescu, G., Hart, D. J., Ryan, D. & Spector, T. D., 2004, In: Osteoarthritis and Cartilage. 12, p. S58 - S58

    Research output: Contribution to journalMeeting abstract

  43. Predictors of structural progression in knee osteoarthritis over 24 months

    Bingham, C., Cline, G., Adami, S., Buckland-Wright, C., Cohen, S., Conaghan, P., Dougados, M., Strand, V., Wenderoth, D., Beary, J. & Meyer, J., 2004, In: Osteoarthritis and Cartilage. 12, p. S136 - S136

    Research output: Contribution to journalMeeting abstract

  44. Risk factors for osteoarthritis: genetics

    Spector, T. D. & MacGregor, A. J., 2004, In: Osteoarthritis and Cartilage. 12 , SUPLL., p. S39 - S44

    Research output: Contribution to journalArticlepeer-review

  45. Subchondral bone changes in hand and knee osteoarthritis detected by radiography

    Buckland-Wright, C., 2004, In: Osteoarthritis and Cartilage. 12, SUPLL., p. S10 - S19

    Research output: Contribution to journalArticlepeer-review

  46. Kellgren & Lawrence grade 1 osteophytes in the knee - doubtful or definite?

    Hart, D. J. & Spector, T. D., 1 Feb 2003, In: Osteoarthritis and Cartilage. 11, 2, p. 149 - 150 2 p.

    Research output: Contribution to journalArticlepeer-review

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