King's College London

Research portal

PL o S Genetics, 1553-7390

Journal

  1. Genomic imprinting: An epigenetic regulatory system

    Bartolomei, M. S., Oakey, R. J. & Wutz, A., 1 Aug 2020, In : PLoS Genetics. 16, 8, p. e1008970

    Research output: Contribution to journalEditorial

  2. Is imprinting the result of “friendly fire” by the host defense system?

    Ondičová, M., Oakey, R. J. & Walsh, C. P., Apr 2020, In : PLoS Genetics. 16, 4, e1008599.

    Research output: Contribution to journalReview article

  3. A meta-analysis of genome-wide association studies of epigenetic age acceleration

    Gibson, J., Russ, T. C., Clarke, T-K., Howard, D. M., Hillary, R., Lewis, K., Walker, R. M., Bermingham, M. L., Morris, S. W., Cambell, A., Hayward, C., Murray, A. D., Porteous, D. J., Horvath, S., Lu, A. T., McIntosh, A., Whalley, H. & Marioni, R., 18 Nov 2019, In : PLoS Genetics. 15, 11

    Research output: Contribution to journalArticle

  4. Genomic insights into neonicotinoid sensitivity in the solitary bee Osmia bicornis

    Beadle, K., Singh, K. S., Troczka, B. J., Randall, E., Zaworra, M., Zimmer, C. T., Hayward, A., Reid, R., Kor, L., Kohler, M., Buer, B., Nelson, D. R., Williamson, M. S., Davies, T. G. E., Field, L. M., Nauen, R. & Bass, C., Feb 2019, In : PLoS Genetics. 15, 2, e1007903.

    Research output: Contribution to journalArticle

  5. Genome-wide association study in Turkish and Iranian populations identify rare familial Mediterranean fever gene (MEFV) polymorphisms associated with ankylosing spondylitis

    Li, Z., Akar, S., Yarkan, H., Lee, S. K., Çetin, P., Can, G., Kenar, G., Çapa, F., Pamuk, O. N., Pehlivan, Y., Cremin, K., De Guzman, E., Harris, J., Wheeler, L., Jamshidi, A., Vojdanian, M., Farhadi, E., Ahmadzadeh, N., Yüce, Z., Dalkılıç, E. & 11 others, Solmaz, D., Akın, B., Dönmez, S., Sarı, I., Leo, P. J., Kenna, T. J., Önen, F., Mahmoudi, M., Brown, M. A., Akkoc, N. & Masters, S. L. (ed.), 2019, In : PLoS Genetics. 15, 4, e1008038.

    Research output: Contribution to journalArticle

  6. Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria

    the 23andMe Research Team, 1 Dec 2018, In : PLoS Genetics. 14, 12, e1007813.

    Research output: Contribution to journalArticle

  7. Dissection of Nidogen function in Drosophila reveals tissue-specific mechanisms of basement membrane assembly

    Dai, J., Estrada, B., Jacobs, S., Sánchez-Sánchez, B. J., Tang, J., Ma, M., Magadán-Corpas, P., Pastor-Pareja, J. C. & Martín-Bermudo, M. D., 27 Sep 2018, In : PLoS Genetics. 14, 9, p. e1007483

    Research output: Contribution to journalArticle

  8. Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain

    Suri, P., Palmer, M. R., Tsepilov, Y. A., Freidin, M. B., Boer, C. G., Yau, M. S., Evans, D. S., Gelemanovic, A., Bartz, T. M., Nethander, M., Arbeeva, L., Karssen, L., Neogi, T., Campbell, A., Mellstrom, D., Ohlsson, C., Marshall, L. M., Orwoll, E., Uitterlinden, A., Rotter, J. I. & 17 others, Lauc, G., Psaty, B. M., Karlsson, M. K., Lane, N. E., Jarvik, G. P., Polasek, O., Hochberg, M., Jordan, J. M., Van Meurs, J. B. J., Jackson, R., Nielson, C. M., Mitchell, B. D., Smith, B. H., Hayward, C., Smith, N. L., Aulchenko, Y. S. & Williams, F. M. K., Sep 2018, In : PLoS Genetics. 14, 9, p. e1007601

    Research output: Contribution to journalArticle

  9. Analysis of motor dysfunction in Down Syndrome reveals motor neuron degeneration

    Watson-Scales, S., Kalmar, B., Lana-Elola, E., Gibbins, D., La Russa, F., Wiseman, F., Williamson, M., Saccon, R., Slender, A., Olerinyova, A., Mahmood, R., Nye, E., Cater, H., Wells, S., Yu, Y. E., Bennett, D. L. H., Greensmith, L., Fisher, E. M. C. & Tybulewicz, V. L. J., 10 May 2018, In : PLoS Genetics. 14, 5, e1007383.

    Research output: Contribution to journalArticle

  10. Genomic locus modulating corneal thickness in the mouse identifies POU6F2 as a potential risk of developing glaucoma

    International Glaucoma Genetics Consortium & NEIGHBORHOOD Consortium, 1 Jan 2018, In : PLoS Genetics. 14, 1, e1007145.

    Research output: Contribution to journalArticle

  11. Non-muscle myosin IIB (Myh10) is required for epicardial function and coronary vessel formation during mammalian development

    Ridge, L. A., Mitchell, K., Al-Anbaki, A., Shaikh Qureshi, W. M., Stephen, L. A., Tenin, G., Lu, Y., Lupu, I. E., Clowes, C., Robertson, A., Barnes, E., Wright, J. A., Keavney, B., Ehler, E., Lovell, S. C., Kadler, K. E. & Hentges, K. E., 30 Oct 2017, In : PL o S Genetics. 13, 10, e1007068.

    Research output: Contribution to journalArticle

  12. Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons

    Li, H., Reksten, T. R., Ice, J. A., Kelly, J. A., Adrianto, I., Rasmussen, A., Wang, S., He, B., Grundahl, K. M., Glenn, S. B., Miceli-Richard, C., Bowman, S., Lester, S., Eriksson, P., Eloranta, M. L., Brun, J. G., Gøransson, L. G., Harboe, E., Guthridge, J. M., Kaufman, K. M. & 44 others, Kvarnström, M., Cunninghame Graham, D. S., Patel, K., Adler, A. J., Farris, A. D., Brennan, M. T., Chodosh, J., Gopalakrishnan, R., Weisman, M. H., Venuturupalli, S., Wallace, D. J., Hefner, K. S., Houston, G. D., Huang, A. J. W., Hughes, P. J., Lewis, D. M., Radfar, L., Vista, E. S., Edgar, C. E., Rohrer, M. D., Stone, D. U., Vyse, T. J., Harley, J. B., Gaffney, P. M., James, J. A., Turner, S., Alevizos, I., Anaya, J. M., Rhodus, N. L., Segal, B. M., Montgomery, C. G., Scofield, R. H., Kovats, S., Mariette, X., Rönnblom, L., Witte, T., Rischmueller, M., Wahren-Herlenius, M., Omdal, R., Jonsson, R., Ng, W. F., Nordmark, G., Lessard, C. J. & Sivils, K. L., 22 Jun 2017, In : PL o S Genetics. 13, 6, e1006820.

    Research output: Contribution to journalArticle

  13. Alternative exon definition events control the choice between nuclear retention and cytoplasmic export of U11/U12-65K mRNA

    Verbeeren, J., Verma, B., Niemelä, E. H., Yap, K., Makeyev, E. V. & Frilander, M. J., 26 May 2017, In : PL o S Genetics. 13, 5, e1006824.

    Research output: Contribution to journalArticle

  14. Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults

    CHARGE Consortium, EPIC-InterAct Consortium, PAGE Consortium, Graff, M., Scott, R. A., Justice, A. E., Young, K. L., Feitosa, M. F., Barata, L., Winkler, T. W., Chu, A. Y., Mahajan, A., Hadley, D., Xue, L., Workalemahu, T., Heard-Costa, N. L., den Hoed, M., Ahluwalia, T. S., Qi, Q., Ngwa, J. S. & 33 others, Renström, F., Quaye, L., Eicher, J. D., Hayes, J. E., Cornelis, M., Kutalik, Z., Lim, E., Luan, J., Huffman, J. E., Zhang, W., Zhao, W., Griffin, P. J., Haller, T., Ahmad, S., Marques-Vidal, P. M., Bien, S., Yengo, L., Teumer, A., Smith, A. V., Kumari, M., Harder, M. N., Justesen, J. M., Kleber, M. E., Hollensted, M., Lohman, K., Rivera, N. V., Whitfield, J. B., Zhao, J. H., Stringham, H. M., Lyytikäinen, L. P., Huppertz, C., Willemsen, G. & Peyrot, W. J., 27 Apr 2017, In : PLoS Genetics. 13, 4, e1006528.

    Research output: Contribution to journalArticle

  15. Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer's disease: Keap1 as a therapeutic target for Alzheimer's Disease

    Kerr, F., Sofola-Adesakin, O., Ivanov, D., Gatliff, J., Gomez Perez-Nievas, B., Bertrand, H., Martinez, P., Callard, R., Snoeren, I., Cocheme, H., Adcott, J., Khericha, M., Castillo-Quan, J., Noble, W., Wells, G., Thornton, J. & Partridge, L., Mar 2017, In : PL o S Genetics. 13, 3, p. 1-30 30 p., e1006593.

    Research output: Contribution to journalArticle

  16. Genetic variants alter T-bet binding and gene expression in mucosal inflammatory disease

    Soderquest, K., Hertweck, A., Giambartolomei, C., Henderson, S., Mohamed, R., Goldberg, R., Perucha, E., Franke, L., Herrero, J., Plagnol, V., Jenner, R. G. & Lord, G. M., 10 Feb 2017, In : PL o S Genetics. 13, 2, e1006587.

    Research output: Contribution to journalArticle

  17. Defining the genetic susceptibility to cervical neoplasia—A genome-wide association study

    Leo, P. J., Madeleine, M. M., Wang, S., Schwartz, S. M., Newell, F., Pettersson-Kymmer, U., Hemminki, K., Hallmans, G., Tiews, S., Steinberg, W., Rader, J. S., Castro, F., Safaeian, M., Franco, E. L., Coutlée, F., Ohlsson, C., Cortes, A., Marshall, M., Mukhopadhyay, P., Cremin, K. & 11 others, Johnson, L. G., Garland, S., Tabrizi, S. N., Wentzensen, N., Sitas, F., Little, J., Cruickshank, M., Frazer, I. H., Hildesheim, A., Brown, M. A. & Plagnol, V., 2017, In : PLoS Genetics. 13, 8

    Research output: Contribution to journalArticle

  18. Craniofacial Ciliopathies and the Interpretation of Hedgehog Signal Transduction

    Liu, K., 29 Dec 2016, In : PL o S Genetics. 12, 12, 4 p., e1006460.

    Research output: Contribution to journalComment/debate

  19. Tbx5 Buffers Inherent Left/Right Asymmetry Ensuring Symmetric Forelimb Formation

    Sulaiman, F. A., Nishimoto, S., Murphy, G. R. F., Kucharska, A., Butterfield, N. C., Newbury-Ecob, R. & Logan, M. P. O., 19 Dec 2016, In : PL o S Genetics. 12, 12, p. e1006521

    Research output: Contribution to journalArticle

  20. No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication Study

    Johnson, E. C., Bjelland, D. W., Howrigan, D. P., Abdellaoui, A., Breen, G., Borglum, A., Cichon, S., Degenhardt, F., Forstner, A. J., Frank, J., Genovese, G., Heilmann-Heimbach, S., Herms, S., Hoffman, P., Maier, W., Mattheisen, M., Morris, D., Mowry, B., Müller-Mhysok, B., Neale, B. & 297 others, Nenadic, I., Nöthen, M. M., O’Dushlaine, C., Rietschel, M., Ruderfer, D. M., Rujescu, D., Schulze, T. G., Simonson, M. A., Stahl, E., Strohmaier, J., Witt, S. H., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M., Alexander, M., Amin, F., Bacanu, S. A., Begemann, M., Belliveau, R. A., Bene, J., Bergen, S. E., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Byerley, W., Cahn, W., Cai, G., Campion, D., Cantor, R. M., Carr, V. J., Carrera, N., Catts, S. V., Chambert, K. D., Chan, R. C. K., Chen, R. Y. L., Chen, E. Y. H., Cheng, W., Cheung, E. F. C., Chong, S. A., Robert Cloninger, C., Cohen, D., Cohen, N., Cormican, P., Craddock, N., Crowley, J. J., Curtis, D., Davidson, M., Davis, K. L., Del Favero, J., Demontis, D., Dikeos, D., Dinan, T., Djurovic, S., Donohoe, G., Drapeau, E., Duan, J., Dudbridge, F., Durmishi, N., Eichhammer, P., Eriksson, J., Escott-Price, V., Essioux, L., Fanous, A. H., Farrell, M. S., Franke, L., Freedman, R., Freimer, N. B., Friedl, M., Friedman, J. I., Fromer, M., Georgieva, L., Giegling, I., Giusti-Rodríguez, P., Godard, S., Goldstein, J. I., Golimbet, V., Gopal, S., Gratten, J., de Haan, L., Hammer, C., Hamshere, M. L., Hansen, M., Hansen, T., Haroutunian, V., Hartmann, A. M., Henskens, F. A., Hirschhorn, J. N., Hoffmann, P., Hofman, A., Hollegaard, M. V., Hougaard, D. M., Ikeda, M., Joa, I., Julià, A., Kahn, R. S., Kalaydjieva, L., Karachanak-Yankova, S., Karjalainen, J., Kavanagh, D., Kennedy, J. L., Khrunin, A., Kim, Y., Klovins, J., Knowles, J. A., Konte, B., Kucinskas, V., Kucinskiene, Z. A., Kuzelova-Ptackova, H., Kähler, A. K., Laurent, C., Chee Keong, J. L., Hong Lee, S., Legge, S. E., Lerer, B., Li, M., Li, T., Liang, K. Y., Lieberman, J., Limborska, S., Loughland, C. M., Lubinski, J., Lönnqvist, J., Macek, M., Magnusson, P. K. E., Maher, B. S., Mallet, J., Marsal, S., Mattingsdal, M., McCarley, R. W., McDonald, C., McIntosh, A. M., Meier, S., Meijer, C. J., Melegh, B., Melle, I., Mesholam-Gately, R. I., Metspalu, A., Michie, P. T., Milani, L., Milanova, V., Mokrab, Y., Morris, D. W., Mors, O., Murphy, K. C., Murray, R. M., Myin-Germeys, I., Müller-Myhsok, B., Nelis, M., Nertney, D. A., Nestadt, G., Nicodemus, K. K., Nikitina-Zake, L., Nisenbaum, L., Nordin, A., O'Callaghan, E., O'Dushlaine, C., Anthony O'Neill, F., Oh, S. Y., Olincy, A., Olsen, L., Van Os, J., Pantelis, C., Papadimitriou, G. N., Papiol, S., Parkhomenko, E., Pato, M. T., Paunio, T., Pejovic-Milovancevic, M., Perkins, D. O., Pietiläinen, O., Pimm, J., Pocklington, A. J., Powell, J., Price, A., Pulver, A. E., Purcell, S. M., Quested, D., Rasmussen, H. B., Reichenberg, A., Reimers, M. A., Richards, A. L., Roffman, J. L., Roussos, P., Salomaa, V., Sanders, A. R., Schall, U., Schubert, C. R., Schwab, S. G., Scolnick, E. M., Scott, R. J., Seidman, L. J., Shi, J., Sigurdsson, E., Silagadze, T., Silverman, J. M., Sim, K., Slominsky, P., Smoller, J. W., So, H. C., Spencer, C. C. A., Stahl, E. A., Stefansson, H., Steinberg, S., Stogmann, E., Straub, R. E., Strengman, E., Scott Stroup, T., Subramaniam, M., Suvisaari, J., Svrakic, D. M., Szatkiewicz, J. P., Söderman, E., Thirumalai, S., Toncheva, D., Tosato, S., Veijola, J., Waddington, J., Walsh, D., Wang, D., Wang, Q., Webb, B. T., Weiser, M., Wildenauer, D. B., Williams, N. M., Williams, S., Wolen, A. R., Wong, E. H. M., Wormley, B. K., Xi, H. S., Zai, C. C., Zheng, X., Zimprich, F., Wray, N. R., Stefansson, K., Visscher, P. M., Adolfsson, R., Andreassen, O. A., Blackwood, D. H. R., Bramon, E., Buxbaum, J. D., Børglum, A. D., Darvasi, A., Domenici, E., Ehrenreich, H., Esko, T., Gejman, P. V., Gill, M., Gurling, H., Hultman, C. M., Iwata, N., Jablensky, A. V., Jönsson, E. G., Kendler, K. S., Kirov, G., Knight, J., Lencz, T., Levinson, D. F., Li, Q. S., Liu, J., Malhotra, A. K., McCarroll, S. A., McQuillin, A., Moran, J. L., Mortensen, P. B., Mowry, B. J., Nöthen, M. M., Ophoff, R. A., Owen, M. J., Palotie, A., Pato, C. N., Petryshen, T. L., Posthuma, D., Riley, B. P., Sham, P. C., Sklar, P., Clair, D. S., Weinberger, D. R., Wendland, J. R., Werge, T., Daly, M. J., O'Donovan, M. C., Sullivan, P. F. & Keller, M. C., 28 Oct 2016, In : PL o S Genetics. 12, 10, e1006343.

    Research output: Contribution to journalArticle

  21. Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis

    Castaño-Betancourt, M. C., Evans, D. S., Ramos, Y. F. M., Boer, C. G., Metrustry, S., Liu, Y., den Hollander, W., van Rooij, J., Kraus, V. B., Yau, M. S., Mitchell, B. D., Muir, K., Hofman, A., Doherty, M., Doherty, S., Zhang, W., Kraaij, R., Rivadeneira, F., Barrett-Connor, E., Maciewicz, R. A. & 17 others, Arden, N., Nelissen, R. G. H. H., Kloppenburg, M., Jordan, J. M., Nevitt, M. C., Slagboom, E. P., Hart, D. J., Lafeber, F., Styrkarsdottir, U., Zeggini, E., Evangelou, E., Spector, T. D., Uitterlinden, A. G., Lane, N. E., Meulenbelt, I., Valdes, A. M. & van Meurs, J. B. J., 4 Oct 2016, In : PL o S Genetics. 12, 10, e1006260.

    Research output: Contribution to journalArticle

  22. Reverse Chemical Genetics: Comprehensive Fitness Profiling Reveals the Spectrum of Drug Target Interactions

    Wong, L. H., Sinha, S., Bergeron, J. R., Mellor, J. C., Giaever, G., Flaherty, P. & Nislow, C., Sep 2016, In : PLoS Genetics. 12, 9, p. e1006275

    Research output: Contribution to journalArticle

  23. Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

    Winkler, T. W., Justice, A. E., Graff, M., Barata, L., Feitosa, M. F., Chu, S., Czajkowski, J., Esko, T., Fall, T., Kilpeläinen, T. O., Lu, Y., Mägi, R., Mihailov, E., Pers, T. H., Rüeger, S., Teumer, A., Ehret, G. B., Ferreira, T., Heard-Costa, N. L., Karjalainen, J. & 31 others, Lagou, V., Mahajan, A., Neinast, M. D., Prokopenko, I., Simino, J., Teslovich, T. M., Jansen, R., Westra, H-J., White, C. C., Absher, D., Ahluwalia, T. S., Ahmad, S., Albrecht, E., Alves, A. C., Bragg-Gresham, J. L., de Craen, A. J. M., Bis, J. C., Lehne, B., Wilson, J. F., Wong, A., Zhao, J. H., Hysi, P. G., Kyriakou, T., Liu, Y-P., Menni, C., Bennett, D. A., Bornstein, S. R., Chambers, J. C., James, A. L., Spector, T. D. & arcOGEN Consortium, Jun 2016, In : PL o S Genetics. 12, 6, p. e1006166

    Research output: Contribution to journalArticle

  24. Bat Accelerated Regions Identify a Bat Forelimb Specific Enhancer in the HoxD Locus

    Booker, B. M., Friedrich, T., Mason, M. K., VanderMeer, J. E., Zhao, J., Eckalbar, W. L., Logan, M., Illing, N., Pollard, K. S. & Ahituv, N., Mar 2016, In : PL o S Genetics. 12, 3, p. e1005738

    Research output: Contribution to journalArticle

  25. The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

    CHARGE Consortium, DIAGRAM Consortium, GLGC Consortium, Global-BPGen Consortium, ICBP Consortium, MAGIC Consortium & arcOGEN Consortium, 1 Oct 2015, In : PL o S Genetics. 11, 10, p. e1005378

    Research output: Contribution to journalArticle

  26. APLP2 Regulates Refractive Error and Myopia Development in Mice and Humans

    Tkatchenko, A. V., Tkatchenko, T. V., Guggenheim, J. A., Verhoeven, V. J. M., Hysi, P. G., Wojciechowski, R., Singh, P. K., Kumar, A., Thinakaran, G. & Williams, C., 27 Aug 2015, In : PL o S Genetics. 11, 8, e1005432.

    Research output: Contribution to journalArticle

  27. A Novel Locus Harbouring a Functional CD164 Nonsense Mutation Identified in a Large Danish Family with Nonsyndromic Hearing Impairment

    Nyegaard, M., Rendtorff, N. D., Nielsen, M. S., Corydon, T. J., Demontis, D., Starnawska, A., Hedemand, A., Buniello, A., Niola, F., Overgaard, M. T., Leal, S. M., Ahmad, W., Wikman, F. P., Petersen, K. B., Crüger, D. G., Oostrik, J., Kremer, H., Tommerup, N., Frödin, M., Steel, K. P. & 2 others, Tranebjærg, L. & Børglum, A. D., 1 Jul 2015, In : PL o S Genetics. 11, 7, e1005386.

    Research output: Contribution to journalArticle

  28. Aurora-A-Dependent Control of TACC3 Influences the Rate of Mitotic Spindle Assembly

    Burgess, S. G., Peset, I., Joseph, N., Cavazza, T., Vernos, I., Pfuhl, M., Gergely, F. & Bayliss, R., 1 Jul 2015, In : PL o S Genetics. 11, 7, e1005345.

    Research output: Contribution to journalArticle

  29. Exome Sequencing in an Admixed Isolated Population Indicates NFXL1 Variants Confer a Risk for Specific Language Impairment

    Villanueva, P., Nudel, R., Hoischen, A., Fernández, M. A., Simpson, N. H., Gilissen, C., Reader, R. H., Jara, L., Echeverry, M. M., Francks, C., Baird, G., Conti-Ramsden, G., O’Hare, A., Bolton, P. F., Hennessy, E. R., Palomino, H., Carvajal-Carmona, L., Veltman, J. A., Cazier, J. B., De Barbieri, Z. & 14 others, Fisher, S. E., Newbury, D. F., Slonims, V., Clark, A., Watson, J., Simonoff, E., Pickles, A., Everitt, A., Seckl, J., Cowie, H., Cohen, W., Nasir, J., Bishop, D. V. M. & Simkin, Z., 17 Mar 2015, In : PL o S Genetics. 11, 3, e1004925.

    Research output: Contribution to journalArticle

  30. HDAC4-Myogenin Axis As an Important Marker of HD-Related Skeletal Muscle Atrophy

    Mielcarek, M., Toczek, M., Smeets, C. J. L. M., Franklin, S. A., Bondulich, M. K., Jolinon, N., Muller, T., Ahmed, M., Dick, J. R. T., Piotrowska, I., Greensmith, L., Smolenski, R. T. & Bates, G., 6 Mar 2015, In : PL o S Genetics. 11, 3, e1005021.

    Research output: Contribution to journalArticle

  31. An Integrative Multi-scale Analysis of the Dynamic DNA Methylation Landscape in Aging

    Yuan, T., Jiao, Y., de Jong, S., Ophoff, R. A., Beck, S. & Teschendorff, A. E., 18 Feb 2015, In : PL o S Genetics. 11, 2, 21 p., e1004996.

    Research output: Contribution to journalArticle

  32. Pooled Sequencing of 531 Genes in Inflammatory Bowel Disease Identifies an Associated Rare Variant in BTNL2 and Implicates Other Immune Related Genes

    Prescott, N. J., Lehne, B., Stone, K., Lee, J. C., Taylor, K., Knight, J., Papouli, E., Mirza, M. M., Simpson, M. A., Spain, S. L., Lu, G., Fraternali, F., Bumpstead, S. J., Gray, E., Amar, A., Bye, H., Green, P., Chung-Faye, G., Hayee, BH., Pollok, R. & 10 others, Satsangi, J., Parkes, M., Barrett, J. C., Mansfield, J. C., Sanderson, J., Lewis, C. M., Weale, M. E., Schlitt, T., Mathew, C. G. & UK IBD Genetics Consortium, 11 Feb 2015, In : PL o S Genetics. 11, 2, 19 p., e1004955.

    Research output: Contribution to journalArticle

  33. Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus

    Mahajan, A., Sim, X., Ng, H. J., Manning, A., Rivas, M. A., Highland, H. M., Locke, A. E., Grarup, N., Im, H. K., Cingolani, P., Flannick, J., Fontanillas, P., Fuchsberger, C., Gaulton, K. J., Teslovich, T. M., Rayner, N. W., Robertson, N. R., Beer, N. L., Rundle, J. K., Bork-Jensen, J. & 243 others, Ladenvall, C., Blancher, C., Buck, D., Buck, G., Burtt, N. P., Gabriel, S., Gjesing, A. P., Groves, C. J., Hollensted, M., Huyghe, J. R., Jackson, A. U., Jun, G., Justesen, J. M., Mangino, M., Murphy, J., Neville, M., Onofrio, R., Small, K. S., Stringham, H. M., Syvänen, A. C., Trakalo, J., Abecasis, G., Bell, G. I., Blangero, J., Cox, N. J., Duggirala, R., Hanis, C. L., Seielstad, M., Wilson, J. G., Christensen, C., Brandslund, I., Rauramaa, R., Surdulescu, G. L., Doney, A. S. F., Lannfelt, L., Linneberg, A., Isomaa, B., Tuomi, T., Jørgensen, M. E., Jørgensen, T., Kuusisto, J., Uusitupa, M., Salomaa, V., Spector, T. D., Morris, A. D., Palmer, C. N. A., Collins, F. S., Mohlke, K. L., Bergman, R. N., Ingelsson, E., Lind, L., Tuomilehto, J., Hansen, T., Watanabe, R. M., Prokopenko, I., Dupuis, J., Karpe, F., Groop, L., Laakso, M., Pedersen, O., Florez, J. C., Morris, A. P., Altshuler, D., Meigs, J. B., Boehnke, M., McCarthy, M. I., Lindgren, C. M., Gloyn, A. L., Abboud, H. E., Afzal, U., Aguilar, D., Arya, R., Atzmon, G., Aung, T., Banks, E., Barroso, I., Barzilai, N., Below, J. E., Bharadwaj, D., Blackwell, T. W., Bonnycastle, L. L., Bowden, D., Carey, J., Carneiro, M. O., Chambers, J. C., Chan, E., Chan, J., Chandak, G. R., Chen, P., Chen, Y., Chen, H., Cheng, C. Y., Chia, K. S., Cho, Y. S., Correa, A., Curran, J. E., Daly, M. J., Day-Williams, A. G., DeFronzo, R. A., DePristo, M., Donnelly, P. J., Ebrahim, S. B., Elliott, P., Esko, T., Fadista, J., Farjoun, Y., Farmer, A. J., Farook, V. S., Fennell, T., Ferreira, T., Fingerlin, T., Forsén, T., Fowler, S. P., Franks, P. W., Frayling, T. M., Freedman, B. I., Froguel, P., Gamazon, E. R., Gieger, C., Glaser, B., Go, M. J., Goldstein, J. I., Grallert, H., Grant, G., Green, T., Griswold, M., Hale, D. E., Han, B. G., Hartl, C., Hattersley, A. T., Hicks, P. J., Hodgkiss, D., Horikoshi, M., Hrabé de Angelis, M., Hu, C., Hu, F. B., Huh, I., Kamran Ikram, M., Illig, T., Jablonski, K. A., Jenkinson, C. P., Jia, W., Kang, H. M., Khor, C. C., Kim, Y., Kim, Y. J., Kim, B. J., Kinnunen, L., Kooner, J. S., Kravic, J., Kriebel, J., Kumar, A., Kumar, S., Kuulasmaa, T., Kwon, M. S., Langenberg, C., Lauritzen, T., Lee, S., Lee, J., Lee, J., Lee, J. Y., Lehman, D. M., Lehne, B., Levy, J. C., Li, J., Liang, L., Lim, W. Y., Lin, K. H., Liu, J., Loh, M., Ma, R. C. W., Ma, C., Mägi, R., Maguire, J., Maxwell, T. J., McVean, G., Meisinger, C., Meitinger, T., Melander, O., Metspalu, A., Mihailov, E., Milani, L., Moutsianas, L., Müller-Nurasyid, M., K. Musani, S., Nagai, Y., Narisu, N., Neale, B. M., Ng, M. C. Y., Nilsson, P., O'Rahilly, S. P., Orho-Melander, M., Owen, K. R., Palmer, N. D., Park, T., Pasko, D., Pearson, R. D., Perry, J. R. B., Peters, A., Pollin, T. I., Poplin, R., Prabhakaran, D., Puppala, S., Purcell, S., Qi, L., Qi, Q., Roden, M., Rolandsson, O., Rosengren, A. H., Sandhu, M., Schwarzmayr, T., Scott, L. J., Scott, R. A., Scott, J., Scott, W. R., Sehmi, J., Shakir, K., Sladek, R., Smith, J. D., Stancáková, A., Strauch, K., Strom, T. M., Swift, A., Tai, E. S., Tajes, J. F., Tan, S. T., Tandon, N., Taylor, H. A., Teo, Y. Y., Thameem, F., Thorand, B., van de Bunt, M., Varga, T. V., Walker, M., Wareham, N. J., Welch, R. P., Wieland, T., Wilson, G., Wong, T. Y., Wood, A. R., Yoon, J., Zeggini, E. & Zhang, W., 27 Jan 2015, In : PL o S Genetics. 11, 1, e1004876.

    Research output: Contribution to journalArticle

  34. hnRNP K coordinates transcriptional silencing by SETDB1 in embryonic stem cells

    Thompson, P. J., Dulberg, V., Moon, K., Foster, L. J., Chen, C., Karimi, M. M., Lorincz, M. C. & Barsh, G. S. (ed.), Jan 2015, In : PLoS Genetics. 11, 1, p. e1004933

    Research output: Contribution to journalArticle

  35. Spinster Homolog 2 (Spns2) Deficiency Causes Early Onset Progressive Hearing Loss

    Chen, J., Ingham, N., Kelly, J., Jadeja, S., Goulding, D., Pass, J., Mahajan, V. B., Tsang, S. H., Nijnik, A., Jackson, I. J., White, J. K., Forge, A., Jagger, D. & Steel, K. P., 1 Oct 2014, In : PLoS Genetics. 10, 10

    Research output: Contribution to journalArticle

  36. Global genetic variations predict brain response to faces

    Dickie, E. W., Tahmasebi, A., French, L., Kovacevic, N., Banaschewski, T., Barker, G. J., Bokde, A., Büchel, C., Conrod, P., Flor, H., Garavan, H., Gallinat, J., Gowland, P., Heinz, A., Ittermann, B., Lawrence, C., Mann, K., Martinot, J-L., Nees, F., Nichols, T. & 10 others, Lathrop, M., Loth, E., Pausova, Z., Rietschel, M., Smolka, M. N., Ströhle, A., Toro, R., Schumann, G., Paus, T. & IMAGEN Consortium, 14 Aug 2014, In : PL o S Genetics. 10, 8, p. e1004523

    Research output: Contribution to journalArticle

  37. Dysfunction of the CNS-Heart Axis in Mouse Models of Huntington's Disease

    Mielcarek, M., Inuabasi, L., Bondulich, M. K., Muller, T., Osborne, G. F., Franklin, S. A., Smith, D. L., Neueder, A., Rosinski, J., Rattray, I., Protti, A. & Bates, G. P., 7 Aug 2014, In : PL o S Genetics. 10, 8, 19 p., e1004550.

    Research output: Contribution to journalArticle

  38. Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index

    Hoggart, C. J., Venturini, G., Mangino, M., Gomez, F., Ascari, G., Zhao, J. H., Teumer, A., Winkler, T. W., Tšernikova, N., Luan, J., Mihailov, E., Ehret, G. B., Zhang, W., Lamparter, D., Esko, T., Macé, A., Rüeger, S., Bochud, P-Y., Barcella, M., Dauvilliers, Y. & 31 others, Benyamin, B., Evans, D. M., Hayward, C., Lopez, M. F., Franke, L., Russo, A., Heid, I. M., Salvi, E., Vendantam, S., Arking, D. E., Boerwinkle, E., Chambers, J. C., Fiorito, G., Grallert, H., Guarrera, S., Homuth, G., Huffman, J. E., Porteous, D., Moradpour, D., Iranzo, A., Hebebrand, J., Kemp, J. P., Lammers, G. J., Aubert, V., Heim, M. H., Martin, N. G., Montgomery, G. W., Spector, T. D., Yuan, W., Bell, J. T. & Generation Scotland Consortium, 1 Jul 2014, In : PL o S Genetics. 10, 7, 12 p., e1004508.

    Research output: Contribution to journalArticle

  39. A Novel MMP12 Locus Is Associated with Large Artery Atherosclerotic Stroke Using a Genome-Wide Age-at-Onset Informed Approach

    Traylor, M., Mäkelä, K-M., Kilarski, L. L., Holliday, E. G., Devan, W. J., Nalls, M. A., Wiggins, K. L., Zhao, W., Cheng, Y-C., Achterberg, S., Malik, R., Sudlow, C., Bevan, S., Raitoharju, E., METASTROKE, International Stroke Genetics Consortium, Wellcome Trust Case Consortium 2 (WTCCC2), Oksala, N., Thijs, V., Lemmens, R., Lindgren, A., Slowik, A. & 19 others, Maguire, J. M., Walters, M., Algra, A., Sharma, P., Attia, J. R., Boncoraglio, G. B., Rothwell, P. M., de Bakker, P. I. W., Bis, J. C., Saleheen, D., Kittner, S. J., Mitchell, B. D., Rosand, J., Meschia, J. F., Levi, C., Dichgans, M., Lehtimäki, T., Lewis, C. M. & Markus, H. S., Jul 2014, In : PL o S Genetics. 10, 7, p. 1-11 11 p., e1004469.

    Research output: Contribution to journalArticle

  40. Phenotypic Dissection of Bone Mineral Density Reveals Skeletal Site Specificity and Facilitates the Identification of Novel Loci in the Genetic Regulation of Bone Mass Attainment

    Kemp, J. P., Medina-Gomez, C., Estrada, K., St Pourcain, B., Heppe, D. H. M., Warrington, N. M., Oei, L., Ring, S. M., Kruithof, C. J., Timpson, N. J., Wolber, L. E., Reppe, S., Gautvik, K., Grundberg, E., Ge, B., van der Eerden, B., van de Peppel, J., Hibbs, M. A., Ackert-Bicknell, C. L., Choi, K. & 13 others, Koller, D. L., Econs, M. J., Williams, F. M. K., Foroud, T., Zillikens, M. C., Ohlsson, C., Hofman, A., Uitterlinden, A. G., Smith, G. D., Jaddoe, V. W. V., Tobias, J. H., Rivadeneira, F. & Evans, D. M., 19 Jun 2014, In : PL o S Genetics. 10, 6, 18 p., e1004423.

    Research output: Contribution to journalArticle

  41. Biased, non-equivalent gene-proximal and -distal binding motifs of orphan nuclear receptor TR4 in primary human erythroid cells

    Shi, L., Sierant, M. C., Gurdziel, K., Zhu, F., Cui, S., Kolodziej, K. E., Strouboulis, J., Guan, Y., Tanabe, O., Lim, K-C. & Engel, J. D., 8 May 2014, In : PLoS Genetics. 10, 5, p. e1004339

    Research output: Contribution to journalArticle

  42. Whole Exome Re-Sequencing Implicates CCDC38 and Cilia Structure and Function in Resistance to Smoking Related Airflow Obstruction

    Wain, L. V., Sayers, I., Artigas, M. S., Portelli, M. A., Zeggini, E., Obeidat, M., Sin, D. D., Bosse, Y., Nickle, D., Brandsma, C-A., Malarstig, A., Vangjeli, C., Jelinsky, S. A., John, S., Kilty, I., McKeever, T., Shrine, N. R. G., Cook, J. P., Patel, S., Spector, T. D. & 3 others, Hollox, E. J., Hall, I. P. & Tobin, M. D., May 2014, In : PL o S Genetics. 10, 5, 14 p., e1004314.

    Research output: Contribution to journalArticle

  43. Genetic Predisposition to In Situ and Invasive Lobular Carcinoma of the Breast

    Sawyer, E., Roylance, R., Petridis, C., Brook, M. N., Nowinski, S., Papouli, E., Fletcher, O., Pinder, S., Hanby, A., Kohut, K., Gorman, P., Caneppele, M., Peto, J., Dos Santos Silva, I., Johnson, N., Swann, R., Dwek, M., Perkins, K., Gillett, C., Houlston, R. & 134 others, Ross, G., De Ieso, P., Southey, M. C., Hopper, J. L., Provenzano, E., Apicella, C., Wesseling, J., Cornelissen, S., Keeman, R., Fasching, P. A., Jud, S. M., Ekici, A. B., Beckmann, M. W., Kerin, M. J., Marme, F., Schneeweiss, A., Sohn, C., Burwinkel, B., Gu??nel, P., Truong, T., Laurent-puig, P., Kerbrat, P., Bojesen, S. E., Nordestgaard, B. G., Nielsen, S. F., Flyger, H., Milne, R. L., Perez, J. I. A., Men??ndez, P., Benitez, J., Brenner, H., Dieffenbach, A. K., Arndt, V., Stegmaier, C., Meindl, A., Lichtner, P., Schmutzler, R. K., Lochmann, M., Brauch, H., Fischer, H., Ko, Y., Nevanlinna, H., Muranen, T. A., Aittom??ki, K., Blomqvist, C., Bogdanova, N. V., D??rk, T., Lindblom, A., Margolin, S., Mannermaa, A., Kataja, V., Kosma, V., Hartikainen, J. M., Chenevix-trench, G., Investigators, K., Lambrechts, D., Weltens, C., Van Limbergen, E., Hatse, S., Chang-claude, J., Rudolph, A., Seibold, P., Flesch-janys, D., Radice, P., Peterlongo, P., Bonanni, B., Volorio, S., Giles, G. G., Severi, G., Baglietto, L., Mclean, C. A., Haiman, C. A., Henderson, B. E., Schumacher, F., Le Marchand, L., Simard, J., Goldberg, M. S., Labr??che, F., Dumont, M., Kristensen, V., Winqvist, R., Pylk??s, K., Jukkola-vuorinen, A., Kauppila, S., Andrulis, I. L., Knight, J. A., Glendon, G., Mulligan, A. M., Devillee, P., Tollenaar, R. A. E. M., Seynaeve, C. M., Kriege, M., Figueroa, J., Chanock, S. J., Sherman, M. E., Hooning, M. J., Hollestelle, A., Van Den Ouweland, A. M. W., Van Deurzen, C. H. M., Li, J., Czene, K., Humphreys, K., Cox, A., Cross, S. S., Reed, M. W. R., Shah, M., Jakubowska, A., Lubinski, J., Jaworska-bieniek, K., Durda, K., Swerdlow, A., Ashworth, A., Orr, N., Schoemaker, M., Couch, F. J., Hallberg, E., Gonz??lez-neira, A., Pita, G., Alonso, M. R., Tessier, D. C., Vincent, D., Bacot, F., Bolla, M. K., Wang, Q., Dennis, J., Michailidou, K., Dunning, A. M., Hall, P., Easton, D., Pharoah, P., Schmidt, M. K., Tomlinson, I., Garcia-closas, M. & Gibson, G. (ed.), 17 Apr 2014, In : PL o S Genetics. 10, 4, 14 p., e1004285.

    Research output: Contribution to journalArticle

  44. A combination of activation and repression by a colinear Hox code controls forelimb-restricted expression of Tbx5 and reveals Hox protein specificity

    Nishimoto, S., Minguillon, C., Wood, S. & Logan, M. P. O., 20 Mar 2014, In : PL o S Genetics. 10, 3, p. N/A 13 p., e1004245.

    Research output: Contribution to journalArticle

  45. An insulin-to-insulin regulatory network orchestrates phenotypic specificity in development and physiology

    Fernandes de Abreu, D., Caballero Reyes, A., Fardel, P., Stroustrup, N., Chen, Z., Lee, K., Keyes, W. D., Nash, Z. M., López-Moyado, I. F., Vaggi, F., Cornils, A., Regenass, M., Neagu, A., Ostojic, I., Liu, M., Cho, Y., Sifoglu, D., Shen, Y., Fontana, W., Lu, H. & 8 others, Csikasz-Nagy, A., Murphy, C. T., Antebi, A., Blanc, E., Apfeld, J., Zhang, Y., Alcedo, J. & Ch'ng, Q., Mar 2014, In : PL o S Genetics. 10, 3, p. 1-15 e1004225.

    Research output: Contribution to journalArticle

  46. The rate of nonallelic homologous recombination in males is highly variable, correlated between monozygotic twins and independent of age

    MacArthur, J. A. L., Spector, T. D., Lindsay, S. J., Mangino, M., Gill, R., Small, K. S. & Hurles, M. E., Mar 2014, In : PL o S Genetics. 10, 3, p. e1004195

    Research output: Contribution to journalArticle

  47. Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease

    Medici, M., Porcu, E., Pistis, G., Teumer, A., Brown, S. J., Jensen, R. A., Rawal, R., Roef, G. L., Plantinga, T. S., Vermeulen, S. H., Lahti, J., Simmonds, M. J., Husemoen, L. L. N., Freathy, R. M., Shields, B. M., Pietzner, D., Nagy, R., Broer, L., Chaker, L., Korevaar, T. I. M. & 98 others, Plia, M. G., Sala, C., Völker, U., Richards, J. B., Sweep, F. C., Gieger, C., Corre, T., Kajantie, E., Thuesen, B., Taes, Y. E., Visser, W. E., Hattersley, A. T., Kratzsch, J., Hamilton, A., Li, W., Homuth, G., Lobina, M., Mariotti, S., Soranzo, N., Cocca, M., Nauck, M., Spielhagen, C., Ross, A., Arnold, A., van de Bunt, M., Liyanarachchi, S., Heier, M., Grabe, H. J., Masciullo, C., Galesloot, T. E., Lim, E. M., Reischl, E., Leedman, P. J., Lai, S., Delitala, A., Bremner, A. P., Philips, D. I. W., Beilby, J. P., Mulas, A., Vocale, M., Abecasis, G., Forsen, T., James, A., Widen, E., Hui, J., Prokisch, H., Rietzschel, E. E., Palotie, A., Feddema, P., Fletcher, S. J., Schramm, K., Rotter, J. I., Kluttig, A., Radke, D., Traglia, M., Surdulescu, G. L., He, H., Franklyn, J. A., Tiller, D., Vaidya, B., de Meyer, T., Jørgensen, T., Eriksson, J. G., O'Leary, P. C., Wichmann, E., Hermus, A. R., Psaty, B. M., Ittermann, T., Hofman, A., Bosi, E., Schlessinger, D., Wallaschofski, H., Pirastu, N., Aulchenko, Y. S., de la Chapelle, A., Netea-Maier, R. T., Gough, S. C. L., Meyer Zu Schwabedissen, H., Frayling, T. M., Kaufman, J-M., Linneberg, A., Räikkönen, K., Smit, J. W. A., Kiemeney, L. A., Rivadeneira, F., Uitterlinden, A. G., Walsh, J. P., Meisinger, C., den Heijer, M., Visser, T. J., Spector, T. D., Wilson, S. G., Völzke, H., Cappola, A., Toniolo, D., Sanna, S., Naitza, S. & Peeters, R. P., Feb 2014, In : PL o S Genetics. 10, 2, p. e1004123

    Research output: Contribution to journalArticle

  48. Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response

    Banerjee, I., Zhang, J., Moore-Morris, T., Pfeiffer, E., Buchholz, K. S., Liu, A., Ouyang, K., Stroud, M. J., Gerace, L., Evans, S. M., McCulloch, A. & Chen, J., Feb 2014, In : PL o S Genetics. 10, 2, e1004114.

    Research output: Contribution to journalArticle

Previous 1 2 3 Next

View graph of relations

© 2018 King's College London | Strand | London WC2R 2LS | England | United Kingdom | Tel +44 (0)20 7836 5454