Basic and Clinical Neuroscience

Projects

Projects per year 1950 2004 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2022 2043

• 6 Not started
• 106 Active
• 1608 Finished

Projects per year

Search results

• Active

  How long-COVID-19 affects the brain: gaining mechanistic insight “in vitro” on how brain cells are disrupted upon exposure to serum from long-COVID-19 patients with neuropsychiatric symptoms (neuro long-COVID-19)

  Borsini, A., Brant, C., Nicholson, T., Pariante, C., Pollak, T. & Srivastava, D.

  Rosetrees Trust

  1/10/2024 → 30/09/2026

  Project: Research

• Studying sex differences in synapse function using brain organoids

  Srivastava, D.

  PSYCHIATRY RESEARCH TRUST

  1/10/2024 → 30/09/2025

  Project: Research

• The Role of Amyloid Pathology in the Thalamus in the Early Stages of Alzheimer's Disease

  Delogu, A. & Giese, P.

  Alzheimer’s Research UK

  1/10/2024 → 30/09/2026

  Project: Research

• Elucidating the non-cell autonomous role of FTD/ALS-linked mutations in p62 in iPSCs-derived astrocytes

  Jimenez Sanchez, M., Mizielinska, S. & Ruepp, M.

  Alzheimer’s Research UK

  1/10/2024 → 30/09/2025

  Project: Research

• Post CCT Fellowship in Neuro-oncology for Neurologists

  Finnerty, G.

  KING'S COLLEGE HOSPITAL CHARITY

  1/09/2024 → 31/08/2025

  Project: Research

• Post CCT Fellowship in Neuro-oncology for Neurologists (Tessa Jowell)

  Finnerty, G.

  Tessa Jowell Brain Cancer Mission

  31/08/2024 → 30/08/2025

  Project: Research

• Spatial Phospho-proteomics Of Long Axons In An Open Human On-chip Motor Neuron Platform

  Hagemann, C.

  UKDRI UK Dementia Research Institute

  1/07/2024 → 30/06/2025

  Project: Research

• Identifying genetic and epigenetic drivers of oligodendrocytes in ageing and Alzheimer's disease

  Marzi, S.

  UKDRI UK Dementia Research Institute

  1/07/2024 → 30/06/2025

  Project: Research

• MNDA Non-Cli: Perturbation of chaperones regulating FG nucleoporin homeostasis in C9ORF72 ALS/FTD: Therapeutic implications for C9ORF72 ALS/FTD. (MNDA Non-Clinical Junior Fellowship Full Application)

  Ruepp, M. & Solomon, D.

  Motor Neurone Disease Association

  1/07/2024 → 30/06/2027

  Project: Research

• Dissecting the molecular determinants of TDP-43 targeting for ALS/FTD

  Mizielinska, S. & Ruepp, M.

  UKDRI UK Dementia Research Institute

  1/07/2024 → 30/06/2025

  Project: Research

• Football and MND

  Al-Chalabi, A.

  My Name'5 Doddie Foundation

  3/06/2024 → 2/06/2025

  Project: Research

• Identifying factors that regulate neuroprotective cold-shock protein RBM3

  Khuperkar, D.

  UKDRI UK Dementia Research Institute

  1/06/2024 → 31/05/2025

  Project: Research

• The role of O-GlcNAcylation as a convergent protective mechanism from ALS/FTD mutations

  James, O. G., Ule, J. & Zagalak, J.

  UKDRI UK Dementia Research Institute

  1/06/2024 → 31/05/2025

  Project: Research

• Developing a genetic screen to identify modifiers of TDP-43 misregulation in FTD

  White, M.

  Alzheimer’s Research UK

  1/05/2024 → 31/12/2024

  Project: Research

• MNDSTaR (MND: MNDSTaR: The King's-LifeArc Solution for Motor Neurone Disease Target Validation

  Al Khleifat, A., Al-Chalabi, A., Iacoangeli, A., Mitchell, J. & Smith, B.

  LifeArc

  1/05/2024 → 30/04/2026

  Project: Research

• Developing AAV Gene therapy for C9orf72 ALS/FTD

  Lee, Y.

  My Name'5 Doddie Foundation

  1/05/2024 → 30/04/2027

  Project: Research

• Investigating neuronal cell cycle re-entry in C9ORF72 ALS/FTD

  Mizielinska, S. & Casterton, R.

  UKDRI UK Dementia Research Institute

  1/04/2024 → 31/03/2025

  Project: Research

• Validating ALS molecular profiles from the UK biobank as a diagnostic tool

  Iacoangeli, A., Al Khleifat, A., Al-Chalabi, A., Breen, G. & Dobson, R.

  LifeArc

  18/03/2024 → 17/03/2026

  Project: Research

• Validating ALS molecular subtypes as biomarkers for patient stratification

  Iacoangeli, A., Al Khleifat, A., Al-Chalabi, A. & Breen, G.

  MND Scotland

  1/03/2024 → 31/08/2025

  Project: Research

• Vectorised U7 snRNAs as gene therapy approach for ALS/FTD

  Ruepp, M.

  UKDRI UK Dementia Research Institute

  1/02/2024 → 31/01/2027

  Project: Research

• Understanding the modifiers of dysregulated RNA metabolism in ALS/FTD

  Ule, J. & James, O. G.

  Wellcome Trust

  1/02/2024 → 31/01/2029

  Project: Research

• MDS-NMS-HD: Validation of the Movement Disorder Society Non Motor Scale in Huntington’s disease

  Valera Bermejo, J., Ray Chaudhuri, K., Williams, S. & van Wamelen, D.

  MRC Medical Research Council

  1/02/2024 → 31/01/2025

  Project: Research

• Neuronal Tau-RNA interactions in health and disease

  Ule, J.

  MRC Medical Research Council

  10/01/2024 → 9/01/2026

  Project: Research

• reference no: Context-dependent RNA regulation and its application in auto-gating therapeutics for brain disorders

  Ule, J., Andreae, L. & Blencowe, B.

  Wellcome Trust

  9/01/2024 → 8/01/2032

  Project: Research

• Alzheimer's Research UK London Network Centre Grant

  Giese, P.

  Alzheimer’s Research UK

  1/01/2024 → 31/12/2024

  Project: Research

• DRI-PRO20232: Capturing the regulatory RNA-binding proteins on Camk2a and Mapt

  Ule, J.

  UKDRI UK Dementia Research Institute

  1/12/2023 → 30/11/2024

  Project: Research

• Developing layer fMRI as a new biomarker of epilepsy in children for treatment optimisation

  Carmichael, D., Aitken, F. & Winston, J.

  GOSH Charity Great Ormond Street Hospital Children's Charity

  1/11/2023 → 30/04/2026

  Project: Research

• DRI-TAP23\3: Mutant FUS degraders as a new therapeutic modality for paediatric and juvenile ALS.

  Ruepp, M.

  UKDRI UK Dementia Research Institute

  1/11/2023 → 28/02/2025

  Project: Research

• LIP: Real-time moLecular dIagnosis of Oral Precancer

  Bergholt, M., Cook, R. & Wojewodka, G.

  EPSRC Engineering and Physical Sciences Research Council

  1/11/2023 → 30/04/2025

  Project: Research

• Development of Patient and Public Involvement for Neurotechnologies

  Valentin Huete, A.

  EPSRC Engineering and Physical Sciences Research Council

  1/11/2023 → 31/10/2024

  Project: Research

• Structural and functional studies of the VAPB-PTPIP51 ER-mitochondria tethering proteins in neurodegenerative diseases

  Miller, C., Atherton, J., Mitchell, J., Noble, W. & Vagnoni, A.

  MRC Medical Research Council

  30/10/2023 → 29/10/2026

  Project: Research

• TBC: NIHR King's College London (Mental Health and Neuroscience) Research Support Service

  Emsley, R., Byford, S., Edwards, M., Kelly, J., Lawrence, V., Norton, S. & academic, A.

  NIHR National Institute For Health & Care Research

  1/10/2023 → 30/09/2028

  Project: Research

• The Phase Separation Dependent And Independent Interactive Of TDP-43

  Hallegger, E. M. & Ruepp, M.

  UKDRI UK Dementia Research Institute

  1/10/2023 → 31/12/2024

  Project: Research

• FULL submission - Dissecting FUS’ cytoplasmic toxic gain-of-function(s) in ALS

  Ruepp, M.

  Motor Neurone Disease Association

  1/10/2023 → 30/09/2026

  Project: Research

• NIHR Pre-doctoral Fellowship Round 5 Triparna Roy

  Iacoangeli, A. & Al-Chalabi, A.

  NIHR National Institute For Health & Care Research

  1/09/2023 → 28/02/2025

  Project: Research

• NIHR Pre-doctoral Fellowship Round 5 Dharti Vasant Kumar

  Iacoangeli, A. & Al-Chalabi, A.

  NIHR National Institute For Health & Care Research

  1/09/2023 → 28/02/2025

  Project: Research

• The CADET Trial (via UCL)

  Valentin Huete, A. & Stavropoulos, I.

  GOSH Charity Great Ormond Street Hospital Children's Charity

  1/09/2023 → 31/08/2026

  Project: Research

• mTOR Pathway Diseases node

  Bateman, J. & Pal, D.

  MRC Medical Research Council

  3/07/2023 → 2/07/2028

  Project: Research

• AI-PROGNOSIS: Artificial intelligence-based Parkinson’s disease risk assessment and prognosis

  Ray Chaudhuri, K.

  TSB Technology Strategy Board

  1/07/2023 → 30/06/2027

  Project: Research

• MAGIC: MAGIC: Next-generation models and genetic therapies for rare neuromuscular diseases

  Zammit, P. & Serio, A.

  TSB Technology Strategy Board

  1/06/2023 → 31/05/2027

  Project: Research

• Testing the in vivo efficacy of subpial delivery of AAV expressing microRNA targeting human ATXN2 as a potential therapy for sporadic MND

  Shaw, C., Brock, O. & Perera, A.

  My Name'5 Doddie Foundation

  1/04/2023 → 31/03/2025

  Project: Research

• AGEing and NuTrition Sensing (AGENT)

  Thuret, S.

  BBSRC Biotechnology and Biological Sciences Research Council

  1/04/2023 → 31/03/2025

  Project: Research

• UK DRI QQ2: UK Dementia Research Institute Centre Award QQ2

  Ule, J., Marzi, S., Mizielinska, S., Ruepp, M. & Shaw, C.

  UKDRI UK Dementia Research Institute

  1/04/2023 → 31/03/2028

  Project: Research

• Disrupted presynaptic proteostasis: a convergent pathomechanism for synaptopathy in frontotemporal dementia and amyotrophic lateral sclerosis.

  Shaw, C.

  Alzheimer’s Research UK

  1/04/2023 → 31/03/2027

  Project: Research

• Novel optogenetic approaches to study mitochondrial biology and neuronal ageing

  Vagnoni, A.

  Leverhulme Trust

  30/03/2023 → 29/03/2026

  Project: Research

• TDP-PATH: Molecular mechanisms of disease onset in TDP43 proteinopathies

  Hirth, F.

  Motor Neurone Disease Association

  1/02/2023 → 31/01/2026

  Project: Research

• Developing AAV gene therapy for Motor Neuron Disease

  Lee, Y. & Shaw, C.

  Motor Neurone Disease Association

  1/02/2023 → 31/01/2026

  Project: Research

• Validating new promising drug targets in Amyotrophic Lateral Sclerosis

  Iacoangeli, A., Al Khleifat, A., Al-Chalabi, A., Mitchell, J., Smith, B. & Sreedharan, J.

  Alzheimer’s Research UK

  1/01/2023 → 1/01/2025

  Project: Research

• Developing a wireless intracranial neuromonitoring device for drug-resistant epilepsyy

  Valentin Huete, A. & Stavropoulos, I.

  NIHR National Institute For Health & Care Research

  1/01/2023 → 31/12/2025

  Project: Research

• NIHR Maudsley BioResource for Mental Health (22-24)

  Breen, G., Al-Chalabi, A., Eley, T., Himmerich, H., Iacoangeli, A., Nicholson, T., Onwumere, J. & Wong, C.

  NIHR National Institute For Health & Care Research

  1/12/2022 → 31/03/2025

  Project: Research