Basic & Medical Biosciences

Research output

Research output per year 1974 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2024

• 805168 Citations
• 7125 Article
• 998 Meeting abstract
• 343 Review article
• 297 Letter
• 1103 More
  • 245 Literature review
  • 162 Editorial
  • 160 Chapter
  • 147 Conference paper
  • 118 Poster abstract
  • 106 Meeting Abstract
  • 81 Comment/debate
  • 26 Book
  • 11 Short survey
  • 10 Other contribution
  • 10 Preprint
  • 8 Book/Film/Article review
  • 6 Patent
  • 4 Abstract
  • 3 Report
  • 2 Commissioned report
  • 2 Other chapter contribution
  • 1 Conference contribution
  • 1 Working paper

Research output per year

Research output per year

Search results

• 2018

  SLOW WAVE ACTIVITY (SWA) UNDER CONDITIONS OF MICROGRAVITY: THE EFFECTS OF 7 DAYS OF WHOLE BODY UNLOADING USING A HYPERBUOYANCY (HBF) FLOATATION BED

  Gnoni, V., Higgins, S. N., Rosenzweig, J., Tsai, C-C., Hasegawa, H., Morris-Paterson, T. E., Green, D. A., Nesbitt, A. D., Ball, T., Cvetkovic, Z., Leschziner, G. D., Harridge, S. D. R. & Rosenzweig, I., 25 Sept 2018, 24th Congress of the European Sleep Research Society (ESRS) 2018. 1 p. A-0951-0030-01314

  Research output: Chapter in Book/Report/Conference proceeding › Poster abstract › peer-review

  • Sleep 100%
  • Electroencephalography 75%
  • Brain 50%
  • Neuroanatomy 25%
  • Polysomnography 25%
• 2017

  Harmonisation des registres de patients atteints d’eczéma atopique nécessitant un traitement systémique. Étude internationale de consensus: Journées Dermatologiques de Paris 2017

  Gerbens, L. A., Apfelbacher, C., Irvine, A. D., Barbarot, S., de Booij, R. J., Boyce, A. E., Deleuran, M., Eichenfield, L. F., Hof, M. H., Middelkamp-Hup, M. A., Roberts, A., Schmitt, J., Vestergaard, C., Wall, D., Weidinger, S., Williamson, P. R., Flohr, C. & Spuls, P. I., Dec 2017, In: Annales De Dermatologie et De Venereologie. 144, 12, Supplement, p. S229-S230

  Research output: Contribution to journal › Poster abstract › peer-review

• The role of domestic water hardness in the development of skin barrier dysfunction and atopic eczema: a systematic review of the literature

  Jabbar-Lopez, Z., Phongphit, V., Ung, C. Y., Chalmers, J., Danby, S., Peacock, J. & Flohr, C., Jul 2017, In: British Journal of Dermatology. 177, Supp. 1, p. 159-159

  Research output: Contribution to journal › Poster abstract › peer-review

  • Skin 100%
  • Water 100%
  • Systematic Review 100%
  • Atopic Dermatitis 100%
  • Development 100%
• 2016

  A Systems Approach to Understanding the Allosteric Mechanism of Pyruvate Kinase M2

  MacPherson, J. A., 16 Feb 2016, In: Biophysical Journal. 110, 3, Supplement 1, p. 52a

  Research output: Contribution to journal › Poster abstract › peer-review
• 2015

  Neural respiratory drive and symptoms that limit exercise in chronic obstructive pulmonary disease

  Jolley, C., Luo, Y., Steier, J., Sylvester, K., Man, W., Rafferty, G., Polkey, M. & Moxham, J., 26 Feb 2015, In: Lancet. 385, S1, p. S51-S51 1 p., 81.

  Research output: Contribution to journal › Poster abstract › peer-review

• Potential for monocyte recruitment by IgE immunotherapy for cancer in a rat model of tumour metastasis

  Josephs, D. H., Bax, H. J., Lentfer, H., Selkirk, C., Spicer, J. F. & Karagiannis, S. N., 26 Feb 2015, In: Lancet. 385 , S1, p. S53-S53 1 p.

  Research output: Contribution to journal › Poster abstract › peer-review

• Towards enabling the semantic access of phenotypic information in clinical letters

  Kudama, S., Berlanga, R., Houlden, H., Jiménez-Ruiz, E., Jonvik, H., Milward, A., Morris, H., Ryten, M., Saklatvala, J., Simpson, M. A. & Wood, N., 2015, In: CEUR Workshop Proceedings. 1546, p. 177-178 2 p.

  Research output: Contribution to journal › Poster abstract › peer-review

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  26 Downloads (Pure)
• 2014

  GRAVITY-LOADING COUNTERMEASURE SKINSUIT (GLCS) TOLERABILITY & PERFORMANCE IN MODELS OF WEIGHTLESSNES

  Green, D., Attias, J., Carvil, P., Fréchette, A. & Waldie, J., Sept 2014, Charite in Space: 6th International congress of MEdicine in Space and extreme Environments (ICMS).

  Research output: Chapter in Book/Report/Conference proceeding › Poster abstract › peer-review

• Neural respiratory drive and breathlessness during incremental cycle and treadmill exercise in chronic obstructive pulmonary disease

  Jolley, C., Luo, Y-M., Steier, J., Rafferty, G., Polkey, M. & Moxham, J., 26 Feb 2014, In: The Lancet. 383, p. 63-63 1 p., S63.

  Research output: Contribution to journal › Poster abstract › peer-review

  • Respiratory Drive 100%
  • Dyspnea 100%
  • Chronic Obstructive Pulmonary Disease 100%
  • Treadmill Exercise 100%
  • Obstructive Lung Disease 100%
• 2013

  Disruption Of PML Nuclear Bodies Cooperates In The Pathogenesis Of Acute Promyelocytic Leukemia

  Moravcsik, E., Joannides, M., Voisset, E., Wessel Stratford, E., Zeisig, B. B., Morris, J., Densham, R., Palgrave, C., Stamp, G., Nye, E., Hills, R. K., Salamoni, P., So, C. W. E., Kogan, S. C., Solomon, E. & Grimwade, D., 15 Nov 2013, In: Blood. 122, 21, p. 3721-3721 1 p., N/A.

  Research output: Contribution to journal › Poster abstract › peer-review

• The role of Coxsackie and adenoviral receptor in TNF alpha driven inflammation in lung epithelial cells

  Hicks, A. P., Morton, P., Parsons, M. & Santis, G., Sept 2013, In: Allergy. 68, s97, p. 224-225 2 p., 536.

  Research output: Contribution to journal › Poster abstract › peer-review
• 2012

  Antibodies of the IgG and IgE classes against the melanoma-associated antigen HMW-MAA: Investigating a new therapeutic approach.

  Karagiannis, P., Gilbert, A. E., Dodev, T., Josephs, D. H., Ali, N., Dafou, D., Ainali, C., Koers, A., Tsoka, S., Kaye, S. B., Spicer, J., J., G. H., Beavil, A., Nestle, F. O. & Karagiannis, S. N., Apr 2012, In: Cancer Research. 72, 8 Suppl. 1, 2524.

  Research output: Contribution to journal › Poster abstract › peer-review

• Development of a gene expression system for enhanced erythroid expression

  Montiel-Equihua, C. A., Zhang, L., Knight, S., Saadeh, H., Scholz, S., Carmo, M., Alonso-Ferrero, M. E., Blundell, M. P., Monkeviciute, A., Schulz, R., Collins, M., Takeuchi, Y., Schmidt, M., Fairbanks, L., Antoniou, M., Thrasher, A. J. & Gaspar, H. B., May 2012, In: Human Gene Therapy. 23, 5, p. A11-A11 1 p., P 012.

  Research output: Contribution to journal › Poster abstract › peer-review

• Interleukin-10-producing B-cell populations in melanoma

  Egbuniwe, I., Mohamad, M. -H., Karagiannis, S. N., Nestle, F. O. & Lacy, K. E., Apr 2012, In: British Journal of Dermatology. 166, 4, p. e35 1 p., P-21.

  Research output: Contribution to journal › Poster abstract
• 2010

  The GENCODE human gene set

  Searle, S., Frankish, A., Bignell, A., Aken, B., Derrien, T., Diekhans, M., Harte, R., Howald, C., Kokocinski, F., Lin, M., Tress, M., Van Baren, M., Barnes, I., Hunt, T., Carvalho-silva, D., Davidson, C., Donaldson, S., Gilbert, J., Kay, M., Lloyd, D., & 14 othersLoveland, J., Mudge, J., Snow, C., Vamathevan, J., Wilming, L., Brent, M., Gerstein, M., Guigó, R., Kellis, M., Reymond, A., Zadissa, A., Valencia, A., Harrow, J. & Hubbard, T., 11 Oct 2010, In: GENOME BIOLOGY. 11, Suppl 1, p. N/A 1 p., P36.

  Research output: Contribution to journal › Poster abstract › peer-review
• 2009

  A retrospective, case cohort study of antitumour necrosis factor therapy in severe acral psoriasis

  Bhargava, K., Barker, JNWN. & Smith, CE., 2009, In: British Journal of Dermatology. 161, p. 32 - 33 2 p.

  Research output: Contribution to journal › Poster abstract

• Inpatient care for psoriasis: a retrospective study of inpatient admission data and the impact of new management modalities in psoriasis

  Jackson, K., Groves, RW., Smith, C. & Barker, JNWN., 2009, In: British Journal of Dermatology. 161, p. 28 - 29 2 p.

  Research output: Contribution to journal › Poster abstract

• In vitro responses of marcophages to E. coli challenge in Crohn's disease.

  Hudspith, B., Rayment, NB., Prescott, N., Parkes, G., Petrovska, L., Brostoff, J., Mathew, CG. & Sanderson, JD., 2009, In: Gastroenterology. 136, 5, p. A250 - A252

  Research output: Contribution to journal › Poster abstract
• 2008

  Acetyl CoA carboxylase (ACACB) Promoter SNP - 8414 C/T is associated with body fat in women and affects promoter activity.

  Lee, AKH., Kyriakou, T., Ge, D., Liu, G., Snieder, H., Spector, TD. & O'Dell, SD., 2008, In: European Journal of Human Genetics. 16, p. 288 - 288 1 p.

  Research output: Contribution to journal › Poster abstract

• Additional filaggrin polymorphisms in early-onset and persistent atopic eczema

  Brown, SJ., Sandilands, A., Zhao, Y., Liao, H., Relton, CL., Meggitt, SJ., Reynolds, NJ., Barker, JN., Trembath, RC., Cordell, HJ. & McLean, WH., 2008, In: British Journal of Dermatology. 159, p. 1241 - 1242 2 p.

  Research output: Contribution to journal › Poster abstract

• Epidermolysis bullosa simplex with mottled pigmentation: clinical and molecular confirmation in five subjects.

  Wong, T., Terron-Kwiatkowski, A., Wojnarowska, FT., Baty, DU., McLean, WHI., McGrath, JA., Martinez, AE. & Mellerio, JE., 2008, In: British Journal of Dermatology. 159, p. 27 - 27 1 p.

  Research output: Contribution to journal › Poster abstract

  1 Citation (Scopus)

• Gene expression profiling can identify novel MRD markers for AML.

  Woodward, EL., Gilkes, AF., Austin, SJ., Green, S., Daly, SB., Yin, JAL., Grimwade, D., Burnett, AK. & Mills, KI., 2008, In: British Journal of Haematology. 141, p. 43 - 44 2 p.

  Research output: Contribution to journal › Poster abstract

• Genetic and functional evidence for a role of the interleukin 23 pathway in the pathogenesis of psoriasis

  di Meglio, P., Tonel, G., Capon, F., Conrad, C., Oldham, E., Kastelein, R., Lanchbury, J., Barker, J., Trembath, R. & Nestle, F., 2008, In: British Journal of Dermatology. 158, 4, p. 890 - 890 1 p.

  Research output: Contribution to journal › Poster abstract

• Genome wide association analysis in human height of European-originated monozygotic female twins.

  Kettunen, JA., Lindqvist, I., Ripatti, S., Spector, TD., Martin, NG., Peltonen, L. & Perola, M., 2008, In: European Journal of Human Genetics. 16, p. 317 - 317 1 p.

  Research output: Contribution to journal › Poster abstract

• IgG antibasement membrane antibodies detected in patients with psoriasis

  DeGiovanni, C., Bhogal, B., Upjohn, E., Allen, M., Barker, JNWN. & Groves, RW., 2008, In: British Journal of Dermatology. 159, p. 45 - 46 2 p.

  Research output: Contribution to journal › Poster abstract

• Osteoprotegerin (OPG) gene variants and the incidence of knee osteoarthritis in the Chingford study.

  Zhang, F., Valdes, A., Hart, DJ., Uitterlinden, A., Zhai, GJ. & Spector, TD., 2008, In: Osteoarthritis and Cartilage. 16, p. S158 - S158

  Research output: Contribution to journal › Poster abstract

  2 Citations (Scopus)

• Site and gender specificity of 8 candidate genes is osteoarthritis of the hip: a study of 780 cases and 672 controls

  Valdes, AM., Doherty, M., Wheeler, M., Doherty, S. & Spector, TD., 2008, In: Osteoarthritis and Cartilage. 16, p. S155 - S155

  Research output: Contribution to journal › Poster abstract
• 2007

  A non-synonymous SNP in an autophagy-related gene is associated with Chron's disease.

  Prescott, NJ., Fisher, SA., Franke, A., Onnie, CM., Hampe, J., Todhunter, CE., Soars, D., Sanderson, J., Forbes, A., Mansfield, J., Lewis, CM., Schreiber, S. & Mathew, CG., 2007, In: Gut. 56, p. A118 - A119

  Research output: Contribution to journal › Poster abstract

• Delineating relative roles for IFNgamma versus IL-23 in psoriasis using human skin reconstructs.

  Qin, IZ., Xin, H., Nestle, FO. & Nickoloff, BJ., 2007, In: Journal of Investigative Dermatology. 127, p. S78 - S78

  Research output: Contribution to journal › Poster abstract

• Effects of biologic therapies on the severity of skin symptoms and quality of life in patients with plaque-type psoriasis: a meta-analysis.

  Reich, K., Sinclair, R., Roberts, G., Griffiths, CEM., Tabberer, M. & Barker, JN., 2007, In: Journal of Investigative Dermatology. 127, p. S29 - S29 170.

  Research output: Contribution to journal › Poster abstract

• Fetal skeletal muscle capillary density is reduced by both early and late gestation maternal undernutrition in sheep

  Rowlerson, A., 2007, In: Proceedings of Physiological Society. PC2.

  Research output: Contribution to journal › Poster abstract

• Functional evidence for a role of interleukin-23 in the pathogenesis of psoriasis.

  Tonel, G., Conrad, C., Qin, JZ., Xin, H., Di Meglio, P., Oldham, E., Kastelein, R., Nickoloff, BJ. & Nestle, FO., 2007, In: Journal of Investigative Dermatology. 127, p. S70 - S70

  Research output: Contribution to journal › Poster abstract

• Gene therapy for beta-thalassemia: studies on human cells.

  Roselli, EA., Cesari, R., Miccio, A., Tiboni, F., Corbella, P., Rossi, C., Biral, E., Marktel, S., Antoniou, M., Andreani, M., Lucarelli, G. & Ferrari, G., 2007, In: Molecular Therapy. 15, p. S249 - S249 651.

  Research output: Contribution to journal › Poster abstract

• Heterozygous nonsense mutation affecting all six isoforms of the p63 gene underlying AEC syndrome.

  Clements, SE., Tan, TY., Ozoemena, L. & McGrath, JA., 2007, In: Journal of Investigative Dermatology. 127, p. S84 - S84

  Research output: Contribution to journal › Poster abstract

• HLA-G 14BP insertion-deletion polymorphism influences response to methotrexate in inflammatory bowel disease.

  Baburajan, B., Prescott, N., Herrlinger, K., Cummings, F., Arenas, M., Smith, M., Tremelling, M., Ansari, A., Parkes, M., Jewell, D., Mathew, C., Marinaki, A. & Sanderson, J., 2007, In: Gut. 56, p. A107 - A107

  Research output: Contribution to journal › Poster abstract

• Identification of the molecular signatures in cutaneous squamous cell carcinoma excised from patients with recessive dystrophic epidermolysis bullosa by using integrated genomic techniques.

  Mao, X., Pourreyron, C., Purdie, K., Holder, MV., Baksh, N., Wong, T., Fassihi, H., Volz, A., Hart, IR., Harwood, C., Proby, CM., Bruckner-Tuderman, L., Kelsell, DP., McGrath, JA., Leigh, IM. & South, AP., 2007, In: British Journal of Dermatology. 156, 5, p. 1110 - 1110 1 p.

  Research output: Contribution to journal › Poster abstract

• Increased expression of collagenase-3, matrilysin-1 and gelatinase B in epidermolysis bullosa-associated cutaneous squamous cell carcinomas.

  Kivisaari, AK., McGrath, J., Bauer, JW., Sawamura, D., Sato-Matsumura, KC., Shimizu, H. & Kahari, V., 2007, In: Journal of Investigative Dermatology. 127, p. S20 - S20

  Research output: Contribution to journal › Poster abstract

• In situ hybridisation for human defensins, lysozyme, SPLA2 and TNFalpha in Crohn's disease and controls.

  Todhunter, CE., Lala, S., Mathew, C., Mansfield, JC. & Keshav, S., 2007, In: Gut. 56, p. A121 - A121

  Research output: Contribution to journal › Poster abstract

• Integration-deficient lentiviral vectors mediate efficient gene transfer to nervous system and muscle.

  Yanez-Munoz, RJ., Foster, E., Yip, P., McMahon, SB., Waddington, S. & Antoniou, M., 2007, In: Molecular Therapy. 15, p. S378 - S378 989.

  Research output: Contribution to journal › Poster abstract

• Is telomere length in peripheral blood lymphocytes correlated with cancer susceptibility or radiosensitivity?

  Hodgson, SV., Barwell, JG., Pangon, L., Kesterton, I., Georgiou, A., Gilchrist, R., Kato, B., Ball, J., Berg, J., Docherty, Z., Aviv, A., Gardner, J., Camplejohn, R. & Spector, TD., 17 Dec 2007, In: European Journal of Human Genetics. 15, 12, p. 149 - 149 1 p., P0516.

  Research output: Contribution to journal › Poster abstract

  38 Citations (Scopus)

• Lentiviral-transduced HSC lead to long-term correction of beta-thalassemia by in vivo selection or erythroid progenitors.

  Miccio, A., Cesari, R., Rossi, C., Tiboni, F., Sanvito, F., Ponzoni, M., Routledge, S., Antoniou, M. & Ferrari, G., 2007, In: Molecular Therapy. 15, p. S96 - S96 250.

  Research output: Contribution to journal › Poster abstract

• MTHFR polymorphisms are of pharmacogenetic value in azathioprine treatment in inflammatory bowel disease.

  Ansari, AR., Arenas, M., Marinaki, A., Duley, J., Greenfield, S., Lewis, C. & Sanderson, J., 2007, In: Gut. 56, p. A105 - A105

  Research output: Contribution to journal › Poster abstract

• Serotonin transporter gene (5-HTT): association analysis with temporal lobe epilepsy.

  Manna, I., Labate, A., Gambardella, A., Forabosco, P., La Russa, A., Le Piane, E., Di Palma, G., Aguglia, U. & Quattrone, A., 21 Jun 2007, In: European Journal of Human Genetics. 15, 1, p. 276 - 276 1 p.

  Research output: Contribution to journal › Poster abstract

  33 Citations (Scopus)

• Sustained increase in COL7A1 gene expression in recessive dystrophic epidermolysis bullosa: evidence for a paracrine effect three months following a single intradermal injection of allogenic fibroblasts.

  Wong, T., Gammon, L., Liu, L., Navsaria, H. & McGrath, JA., 2007, In: Journal of Investigative Dermatology. 127, p. S86 - S86

  Research output: Contribution to journal › Poster abstract

• The pharmacogenetics of folate and purine metabolic pathways in methotrexate therapy of inflammatory bowel disease.

  Baburajan, B., Arenas, M., Prescott, N., Herrlinger, K., Cummings, F., Tremelling, M., Parkes, M., Hewell, D., Mathew, C., Marinaki, A. & Sanderson, J., 2007, In: Gut. 56, p. A106 - A106

  Research output: Contribution to journal › Poster abstract

• The pharmacogenetics of methotrexate therapy in inflammatory bowel disease.

  Baburajan, B., Prescott, N., Arenas, M., Soon, SY., Ansari, A., Herrlinger, K., Cummings, F., Tremelling, M., Parkes, M., Jewell, DP., Mathew, C., Marinaki, AM. & Sanderson, JD., 2007, In: Gastroenterology. 134, 4, p. A-173 - A-173

  Research output: Contribution to journal › Poster abstract

• Variable patterns of kindlin-1 skin immunolabelling resulting from KIND1 gene mutations in Kindler syndrome.

  Lai-Cheong, JE. & McGrath, JA., 2007, In: Journal of Investigative Dermatology. 127, p. S84 - S84

  Research output: Contribution to journal › Poster abstract
• 2006

  A genome-wide scan and HCRTR2 candidate gene analysis in a European cluster headache cohort.

  Baumber, L., Sjostrand, C., Leone, M., Harty, H., Bussone, G., Hillert, J., Trembath, RC. & Russell, MB., Jun 2006, In: Cephalalgia. 26, 11, p. 1363 - 1364 2 p.

  Research output: Contribution to journal › Poster abstract

  61 Citations (Scopus)

• Association of CARD15 variants with clinical subtypes of Crohn's disease: a study of 630 cases.

  Onnie, C., Fisher, S., Forbes, A., Sanderson, J., Lewis, C. & Mathew, C., 2006, In: Gastroenterology. 130, 4, p. A592 - A592

  Research output: Contribution to journal › Poster abstract

• Blockade of VLA-2, (alpha2beta1 integrin) inhibits psoriasis in a T-cell-independent manner

  Tonel, G., Curdin, C., Nestle, F. O. & Gardner, H., 2006, In: British Journal of Dermatology. 154, 1, p. U36 - U36

  Research output: Contribution to journal › Poster abstract