Basic & Medical Biosciences

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• X-ray and NMR spectroscopy applied to the structural analysis of S. pneumoniae ParC and Human Cardiac MLP protein

  Author: Laponogov, I., 2007

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Xeroderma pigmentosum: A disease model for clinical, cellular and molecular consequences of ultraviolet radiation-induced damage

  Author: Sethi, M. K., 2017

  Supervisor: Young, A. R. (Supervisor) & Fassihi, H. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Validation of the IL-36 receptor as a potential therapeutic target in pustular and plaque psoriasis

  Author: Mahil, S. K., 1 Dec 2017

  Supervisor: Capon, F. (Supervisor) & Barker, J. N. W. N. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Validation of HDAC6 and SIRT2 Tubulin Deacetylases as therapeutic targets for Huntington’s Disease.

  Author: Bobrowska, A., 1 May 2012

  Supervisor: Bates, G. (Supervisor) & Antoniou, M. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• UVA-induced oxidative stress and DNA damage in human skin cells and photoprotection by antioxidant compounds

  Author: Delinassios, G., 2012

  Supervisor: Young, A. P. (Supervisor) & Cooke, M. (External person) (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Using human induced pluripotent stem cells to identify genetic variants that influence cellular differentiation

  Author: Vickers, A., 1 Sept 2021

  Supervisor: Watt, F. (Supervisor) & Lieberam, I. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Uses of atomistic simulations and free energy calculations to probe ligand binding and diffusion into proteins

  Author: Jorgensen, C. D., 1 Dec 2018

  Supervisor: Lorenz, C. (Supervisor) & Fraternali, F. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Understanding the roles of lipids in the Golgi membranes

  Author: Mukhwana, N., 1 Jun 2022

  Supervisor: Eggert, U. S. (Supervisor) & Carlton, J. G. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Understanding the functional implications of differential integrin expression in cardiomyocytes

  Author: Hawkes, W., 1 Jun 2020

  Supervisor: Iskratsch, T. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Understanding the dynamics of biological networks through minimal switches and timekeepers

  Author: Hernansaiz Ballesteros, R. D., 2018

  Supervisor: Csikasz-Nagy, A. (Supervisor) & Cardelli, L. (External person) (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Tumour microenvironment reprogramming suppresses breast cancer

  Author: Perdrix Rosell, A., 1 Jul 2020

  Supervisor: Malanchi, I. (External person) (Supervisor) & Sanz Moreno, V. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Transcriptional programs controlling actomyosin contractility in melanoma

  Author: Cantelli, G., 2016

  Supervisor: Sanz Moreno, V. M. (Supervisor) & Ridley, A. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Towards hES cell-based therapy of Epidermolysis Bullosa

  Author: Petrova, A., 2012

  Supervisor: McGrath, J. A. (Supervisor) & Ilic, D. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The Use of Epidermal Growth Factor Receptor Activity Biosensing to Understand Cancer Gene Network Sensitivity and to Monitor Intratumoural Heterogeneity.

  Author: Cheung, A. & Cheung, A., 2013

  Supervisor: Ng, T. T. (Supervisor) & Gillett, C. E. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The structure and regulation of the actin cytoskeleton during B cell antigen internalisation

  Author: Roper, S. I., 1 May 2019

  Supervisor: Cox, S. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• The role of WASP-Interacting Protein (WIP) in regulating the assembly and function of podosomes 

  Author: Vijayakumar, V., 2013

  Supervisor: Jones, G. E. (Supervisor) & Wells, C. M. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• The role of the ESCRT-III component CHMP4C in preserving genomic integrity

  Author: Kuzeva, D., 1 Jul 2022

  Supervisor: Martin Serrano, J. (Supervisor) & Ng, T. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The role of phosphoinositide 3-kinases and Rac GTPases in vascular inflammation

  Author: Chaudhry, H., 1 Sept 2022

  Supervisor: Brain, S. (Supervisor) & Ridley, A. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The role of lupus susceptibility MHC haplotypes and interferon-alpha in gene regulation

  Author: Salgado Teixeira Duarte, C., 2017

  Supervisor: Fernando, M. M. A. (Supervisor) & Vyse, T. J. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The Role of Lamellipodin in Breast Cancer Progression

  Author: Perera, K. U. L., 2015

  Supervisor: Krause, M. J. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• The role of interleukin-36 in skin and systemic inflammation

  Author: Catapano, M., 17 Jul 2019

  Supervisor: Capon, F. (Supervisor), Ciccarelli, F. (Supervisor), Barker, J. (Supervisor) & Smith, C. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The role of human CD23 in lgE homeostasis & allergic disease

  Author: Cooper, A., 1 Feb 2013

  Supervisor: Sutton, B. J. (Supervisor) & Gould, H. J. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The role of DNA sequence signals in the epigenetic reprogramming of CpG islands during oogenesis and early embryogenesis

  Author: Saadeh, H., 2014

  Supervisor: Schulz, R. S. D. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The role of deubiquitinase USP7 in the regulation of pancreatic pro-endocrine factor NGN3

  Author: Manea, T., 1 Sept 2022

  Supervisor: Sancho, R. (Supervisor) & Spagnoli, F. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The role of abnormal neutrophil activation in psoriasis

  Author: Vergnano, M., 1 Mar 2020

  Supervisor: Capon, F. (Supervisor) & Smith, C. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The process of endocytosis of CD23.

  Author: Karagiannis, S., 1995

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The musical language of Elliott Carter : analysis of selected works from the transitional period (1945-55).

  Author: King, S. J. T., 1998

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The Molecular Biology of Sickle Cell Anaemia

  Author: Shannon, M. F., 2018

  Supervisor: Oakey, R. (Supervisor) & Thein, S. L. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The Molecular Basis of the Frank-Starling Relationship

  Author: Zhang, X., 2016

  Supervisor: Irving, M. (Supervisor) & Sun, Y. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• THE INVOLVEMENT OF P38GAMMA MAPK IN PATHOLOGICAL CARDIAC HYPERTROPHY

  Author: Clark, J. & Loonat, A. A., 1 Apr 2016

  Supervisor: Marber, M. S. (Supervisor) & Clark, J. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Medicine

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• The impact of cannabis use and polygenic risk scores on symptom dimension profiles at psychosis onset

  Author: Quattrone, D., 1 Sept 2020

  Supervisor: Di Forti, M. (Supervisor), Murray, R. (Supervisor), Lewis, C. (Supervisor) & Reininghaus, U. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The genetics of oesophageal cancer in South African populations

  Author: Bye, H., Nov 2013

  Supervisor: Mathew, C. G. P. (Supervisor) & Lewis, C. M. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• THE GENETIC BASIS OF PUSTULAR PSORIASIS AND ITS OVERLAP WITH PSORIASIS VULGARIS

  Author: Berki, D. M., 2016

  Supervisor: Capon, F. (Supervisor), Trembath, R. C. (Supervisor) & Barker, J. N. W. N. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The Evolution of Immunoglobulin E

  Author: Doré, K. A., 2015

  Supervisor: Sutton, B. J. (Supervisor) & Beavil, A. J. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The epigenetics and role of Dopa Decarboxylase in heart development

  Author: Prickett, A., 2013

  Supervisor: Oakey, R. J. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The epigenetic regulation of cerebellar granule cell development

  Author: Riegman, K., 1 Feb 2020

  Supervisor: Basson, A. (Supervisor) & Osborne, C. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• The Epidermal Growth Factor Receptor Regulates Cell Autonomous Pro-inflammatory Signalling in Keratinocytes

  Author: Hayday, T., 1 Apr 2020

  Supervisor: Parsons, M. (Supervisor) & McGrath, J. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The Effects of Ageing and Obesity on the Contractile Properties of Isolated Locomotory and Respiratory Skeletal Muscles

  Author: Hill, C., 4 Apr 2019

  Supervisor: Tallis, J. (External person) (Supervisor), James, R. S. (External person) (Supervisor) & Cox, V. M. (External person) (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• The effect of water hardness on atopic eczema and skin barrier function

  Author: Jabbar-Lopez, Z., 1 Aug 2023

  Supervisor: Flohr, C. (Supervisor) & Peacock, J. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The Effect of Transcranial Direct Current Stimulation on Discourse Production in Post-Stroke Chronic Aphasia

  Author: Matar, S., 1 Apr 2022

  Supervisor: Pavlou, M. (Supervisor) & Sorinola, I. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The effect of hydroxyurea treatment on DNA methylation and gene expression in essential thrombocythaemia and polycythaemia vera: a cross-species study

  Author: Contreras Castillo, S., 1 Apr 2020

  Supervisor: Oakey, R. (Supervisor) & Schulz, R. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The effect of axial body loading – via the "SkinSuit" – on human movement. 

  Author: Attias, J., 2018

  Supervisor: Green, D. (Supervisor) & Russomano, T. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The development of gene therapy for recessive dystrophic epidermolysis bullosa

  Author: Abdul Wahab, A. O., 2017

  Supervisor: McGrath, J. A. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• The Development and Function of Cerebellar Nucleo-Olivary Neurons

  Author: Prekop, H., 2018

  Supervisor: Wingate, R. (Supervisor), Logan, M. (Supervisor) & Delogu, A. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The development and evaluation of a structured conditioning programme on physiological performance under conditions of high +Gz

  Author: Slungaard, E., 1 Dec 2018

  Supervisor: Harridge, S. D. R. (Supervisor) & Newham, D. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The Cks1/Cks2 Axis In Mll1-Dependent Wnt Signalling And Mixed Lineage Leukaemia

  Author: Grey, W. G., 2015

  Supervisor: Solomon, E. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• The characterisation of cellular and tissue chronic inflammation in recessive dystrophic epidermolysis bullosa

  Author: Proudfoot, L. E., 2015

  Supervisor: McGrath, J. A. (Supervisor) & Nestle, F. O. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The Application of Surface Electromyographic Biofeedback in Dysphagia Rehabilitation in Acute Stroke

  Author: Archer, S., 2014

  Supervisor: Newham, D. J. (Supervisor) & Smith, C. (External person) (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Targeting of B-cell malignancy using novel parallel chimeric antigen receptor (pCAR) engineered T-cells

  Author: Halim, L., 1 Jul 2021

  Supervisor: Maher, J. (Supervisor) & Dillon, R. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Tailoring protein nanomechanics through chemical reactivity with single bond resolution

  Author: Beedle, A. E. M., 2018

  Supervisor: Garcia-Manyes, S. (Supervisor) & Richards, D. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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