King's College London

Research portal

Cancer Cell Biology & Imaging

Organisational unit: Department

  1. Accepted/In press
  2. HER2-HER3 heterodimer quantification by FRET-FLIM and patient subclass analysis of the COIN colorectal trial

    Barber, P. R., Weitsman, G., Lawler, K., Barrett, J., Rowley, M., Rodriguez-Justo, M., Fisher, D., Gao, F., Tullis, I. D. C., Deng, J., Brown, L., Kaplan, R., Hochhauser, D., Adams, R., Maughan, T. S., Vojnovic, B., Coolen, A. C. C. & Ng, T., 18 Dec 2019, In : Journal of the National Cancer Institute.

    Research output: Contribution to journalArticle

  3. LPS-Induced Lung Platelet Recruitment Occurs Independently from Neutrophils, PSGL-1, and P-selectin

    Cleary, S. J., Hobbs, C., Amison, R. T., Arnold, S., O'Shaughnessy, B. G., Lefrançais, E., Mallavia, B., Looney, M. R., Page, C. P. & Pitchford, S. C., 1 Aug 2019, In : American Journal of Respiratory Cell and Molecular Biology. 61, 2, p. 232-243 12 p.

    Research output: Contribution to journalArticle

  4. Potassium channel activity controls breast cancer metastasis by affecting β-catenin signaling

    Breuer, E. K., Fukushiro-Lopes, D., Dalheim, A., Burnette, M., Zartman, J., Kaja, S., Wells, C., Campo, L., Curtis, K. J., Romero-Moreno, R., Littlepage, L. E., Niebur, G. L., Hoskins, K., Nishimura, M. I. & Gentile, S., 1 Mar 2019, In : Cell Death and Disease. 10, 3, 180.

    Research output: Contribution to journalArticle

  5. Multifocal multiphoton volumetric imaging approach for high-speed time-resolved Förster resonance energy transfer imaging in vivo

    Poland, S. P., Chan, G. K., Levitt, J. A., Krstajić, N., Erdogan, A. T., Henderson, R. K., Parsons, M. & Ameer-Beg, S. M., 15 Dec 2018, In : Optics Letters. 43, 24, p. 6057-6060 4 p.

    Research output: Contribution to journalArticle

  6. The architecture of EGFR’s basal complexes reveals autoinhibition mechanisms in dimers and oligomers

    Zanetti-Domingues, L. C., Korovesis, D., Needham, S. R., Tynan, C. J., Sagawa, S., Roberts, S. K., Kuzmanic, A., Ortiz-Zapater, E., Jain, P., Roovers, R. C., Lajevardipour, A., van Bergen en Henegouwen, P. M. P., Santis, G., Clayton, A. H. A., Clarke, D. T., Gervasio, F. L., Shan, Y., Shaw, D. E., Rolfe, D. J., Parker, P. J. & 1 others, Martin-Fernandez, M. L., 1 Dec 2018, In : Nature Communications. 9, 1, 4325.

    Research output: Contribution to journalArticle

  7. Accepted/In press

    A multifocal multiphoton volumetric imaging approach for high speed time-resolved FRET imaging in vivo

    Poland, S. P., Chan, G. K. Y., Levitt, J. A., Krstajić, N., Erdogan, A., Henderson, R., Parsons, M. & Ameer-Beg, S., 1 Nov 2018, (Accepted/In press) In : Optics Letters. 4 p.

    Research output: Contribution to journalLetter

  8. Anti-Folate Receptor alpha-directed Antibody Therapies Restrict the Growth of Triple Negative Breast Cancer

    Cheung, A., Opzoomer, J. W., Ilieva, K. M., Gazinska, P., Hoffmann, R. M., Mirza, H., Marlow, R., Francesch-Domenech, E., Fittall, M. W., Dominguez Rodriguez, D., Clifford, A., Badder, L., Patel, N., Mele, S., Pellizzari, G., Bax, H. J., Crescioli, S., Petranyi, G., Larcombe-Young, D., Josephs, D. H. & 9 others, Canevari, S., Figini, M., Pinder, S. E., Nestle, F. O., Gillett, C., Spicer, J., Grigoriadis, A., Tutt, A. & Karagiannis, S. N., 15 Oct 2018, In : Clinical Cancer Research. 24, 20, p. 5098-5111

    Research output: Contribution to journalArticle

  9. A phase I study to assess afatinib in combination with carboplatin or with carboplatin plus paclitaxel in patients with advanced solid tumors

    O’Brien, M. E. R., Sarker, D., Bhosle, J., Thillai, K., Yap, T. A., Uttenreuther-Fischer, M., Pemberton, K., Jin, X., Wiebe, S., De Bono, J. & Spicer, J., 7 Aug 2018, In : Cancer Chemotherapy and Pharmacology.

    Research output: Contribution to journalArticle

  10. ALIX Regulates Tumor-Mediated Immunosuppression by Controlling EGFR Activity and PD-L1 Presentation

    Monypenny, J., Milewicz, H., Flores-Borja, F., Weitsman, G., Cheung, A., Chowdhury, R., Burgoyne, T., Arulappu, A., Lawler, K., Barber, P. R., Vicencio, J. M., Keppler, M., Wulaningsih, W., Davidson, S. M., Fraternali, F., Woodman, N., Turmaine, M., Gillett, C., Franz, D., Quezada, S. A. & 6 others, Futter, C. E., Von Kriegsheim, A., Kolch, W., Vojnovic, B., Carlton, J. G. & Ng, T., 17 Jul 2018, In : Cell Reports. 24, 3, p. 630-641 12 p.

    Research output: Contribution to journalArticle

  11. Protein kinase D displays intrinsic Tyr autophosphorylation activity: insights into mechanism and regulation

    Cobbaut, M., Derua, R., Parker, P. J., Waelkens, E., Janssens, V. & Van Lint, J., 1 Jul 2018, In : FEBS Letters. 592, 14, p. 2432-2443 12 p.

    Research output: Contribution to journalArticle

  12. Protein Kinase C-β Dictates B Cell Fate by Regulating Mitochondrial Remodeling, Metabolic Reprogramming, and Heme Biosynthesis

    Tsui, C., Martinez-Martin, N., Gaya, M., Maldonado, P., Llorian, M., Legrave, N. M., Rossi, M., MacRae, J. I., Cameron, A. J., Parker, P. J., Leitges, M., Bruckbauer, A. & Batista, F. D., 5 Jun 2018, In : Immunity.

    Research output: Contribution to journalArticle

  13. Perspectives on chimeric antigen receptor T-cell immunotherapy for solid tumors

    Kosti, P., Maher, J. & Arnold, J. N., 22 May 2018, In : Frontiers in Immunology. 9, MAY, 1104.

    Research output: Contribution to journalShort survey

  14. A new TAO kinase inhibitor reduces tau phosphorylation at sites associated with neurodegeneration in human tauopathies

    Giacomini, C., Koo, C. Y., Yankova, N., Tavares, I. A. F., Wray, S., Noble, W. J., Hanger, D. P. & Morris, J. D. H., 7 May 2018, In : Acta Neuropathologica Communications. 6, 37, p. 1-16 16 p., Acta Neuropathologica Communications 2018 6:37.

    Research output: Contribution to journalArticle

  15. Protein kinase N1 critically regulates cerebellar development and long-term function

    Nedden, S. Z., Eith, R., Schwarzer, C., Zanetti, L., Seitter, H., Fresser, F., Koschak, A., Cameron, A. J., Parker, P. J., Baier, G. & Baier-Bitterlich, G., 1 May 2018, In : The Journal of clinical investigation. 128, 5, p. 2076-2088 13 p.

    Research output: Contribution to journalArticle

  16. PAK4 pathway as a potential therapeutic target in pancreatic cancer

    Thillai, K., Sarker, D. & Wells, C., Mar 2018, In : Future Oncology. 14, 7, p. 579-582 4 p.

    Research output: Contribution to journalReview article

  17. Chondroitin sulfate proteoglycan 4 and its potential as an antibody immunotherapy target across different tumor types

    Ilieva, K. M., Cheung, A., Mele, S., Chiaruttini, G., Crescioli, S., Griffin, M., Nakamura, M., Spicer, J. F., Tsoka, S., Lacy, K. E., Tutt, A. N. J. & Karagiannis, S. N., 10 Jan 2018, In : Frontiers in Immunology. 8, JAN, p. 1911 15 p., 1911.

    Research output: Contribution to journalReview article

  18. PKCε Controls Mitotic Progression by Regulating Centrosome Migration and Mitotic Spindle Assembly

    Martini, S., Soliman, T., Gobbi, G., Mirandola, P., Carubbi, C., Masselli, E., Pozzi, G., Parker, P. J. & Vitale, M., Jan 2018, In : MOLECULAR CANCER RESEARCH. 16, 1, p. 3-15 13 p.

    Research output: Contribution to journalArticle

  19. Carboplatin in BRCA1/2-mutated and triple-negative breast cancer BRCAness subgroups: the TNT Trial

    Tutt, A., Tovey, H., Cheang, M. C. U., Kernaghan, S., Kilburn, L., Gazinska, P., Owen, J., Abraham, J., Barrett, S., Barrett-Lee, P., Brown, R., Chan, S., Dowsett, M., Flanagan, J. M., Fox, L., Grigoriadis, A., Gutin, A., Harper-Wynne, C., Hatton, M. Q., Hoadley, K. A. & 19 others, Parikh, J., Parker, P., Perou, C. M., Roylance, R., Shah, V., Shaw, A., Smith, I. E., Timms, K. M., Wardley, A. M., Wilson, G., Gillett, C., Lanchbury, J. S., Ashworth, A., Rahman, N., Harries, M., Ellis, P., Pinder, S. E., Bliss, J. M. & TNT Trialists, 2018, In : Nature Medicine. 24, p. 628–637

    Research output: Contribution to journalArticle

  20. Live Cell Imaging: Tracking Cell Movement

    De Piano, M., Jones, G. E. & Wells, C. M., 2018, Standard and Super-Resolution Bioimaging Data Analysis: A Primer. Wheeler, A. & Henriques, R. (eds.). UK: John Wiley & Sons, Ltd, p. 173-200

    Research output: Chapter in Book/Report/Conference proceedingChapter

  21. In vivo imaging of pro- and antitumoral cellular components of the tumor microenvironment

    Helfen, A., Roth, J., Ng, T. & Eisenblaetter, M., 7 Dec 2017, In : Journal of Nuclear Medicine. 59, 2, p. 183-188 6 p.

    Research output: Contribution to journalArticle

  22. Mutational landscape of lymph node metastasis exomes in breast cancers

    Guo, Q., Lawyer, K., Gillett, C., Pai, T., Quist, J., Nowinski, S., Simpson, M., Ng, T. & Grigoriadis, A., Nov 2017, In : European Journal of Surgical Oncology. 43, 11, p. 2228 1 p.

    Research output: Contribution to journalArticle

  23. Gene expression modules in primary breast cancers as risk factors for organotropic patterns of first metastatic spread: a case-control study

    Lawler, K., Papouli, E., Naceur-Lombardelli, C., Mera, A., Ougham, K., Tutt, A., Kimbung, S., Hedenfalk, I., Zhan, J., Zhang, H., Buus, R., Dowsett, M., Ng, T., Pinder, S. E., Parker, P. J. J., Holmberg, L. H., Gillett, C. E., Grigoriadis, A. & Purushotham, A. D., 13 Oct 2017, In : Breast Cancer Research. 19, 15 p.

    Research output: Contribution to journalArticle

  24. Time resolved amplified FRET identifies protein kinase B activation state as a marker for poor prognosis in clear cell renal cell carcinoma

    Miles, J., Applebee, C. J., Leboucher, P., Lopez-Fernandez, S., Lee, D-J., Guarch, R., Ward, S., Parker, P. J., López, J. I. & Larijani, B., 13 Oct 2017, In : BBA Clinical. p. 97-102

    Research output: Contribution to journalArticle

  25. Glycerol-3-phosphate acyltransferase 1 promotes tumor cell migration and poor survival in ovarian carcinoma

    Marchan, R., Büttner, B., Lambert, J., Edlund, K., Glaeser, I., Blaszkewicz, M., Leonhardt, G., Marienhoff, L., Kaszta, D., Anft, M., Watzl, C., Madjar, K., Grinberg, M., Rempel, E., Hergenröder, R., Selinski, S., Rahnenführer, J., Lesjak, M. S., Stewart, J. D., Cadenas, C. & 1 others, Hengstler, J. G., 1 Sep 2017, In : Cancer Research. 77, 17, p. 4589-4601 13 p.

    Research output: Contribution to journalArticle

  26. Information-adaptive clinical trials with selective recruitment and binary outcomes

    Barrett, J. E., 15 Aug 2017, In : Statistics in Medicine. 36, 18, p. 2803-2813 11 p.

    Research output: Contribution to journalArticle

  27. Engineering Pak1 Allosteric Switches

    Dagliyan, O., Karginov, A. V., Yagishita, S., Gale, M. E., Wang, H., Dermardirossian, C., Wells, C. M., Dokholyan, N. V., Kasai, H. & Hahn, K. M., 21 Jul 2017, In : ACS synthetic biology. 6, 7, p. 1257-1262 6 p.

    Research output: Contribution to journalLetter

  28. Visualization of tumor-immune interaction: Target-specific imaging of S100A8/A9 reveals pre-metastatic niche establishment

    Eisenblaetter, M., Flores-Borja, F., Lee, J. J., Wefers, C., Smith, H., Hueting, R., Cooper, M. S., Blower, P. J., Patel, D., Rodriguez-Justo, M., Milewicz, H., Vogl, T., Roth, J., Tutt, A., Schaeffter, T. & Ng, T., 15 Jun 2017, In : Theranostics. 7, 9, p. 2392-2401 10 p.

    Research output: Contribution to journalArticle

  29. Stratifying cancer therapies by molecular interactions and imaging

    Galazi, M., Weitsman, G., Monypenny, J., Coban, O., Milewicz, H., Gomez, V., Ciccarelli, F. & Ng, T., 23 May 2017, Mechanisms of Molecular Carcinogenesis. Springer International Publishing Switzerland, Vol. 2. p. 315-358 44 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  30. PAK5 mediates cell: cell adhesion integrity via interaction with E-cadherin in bladder cancer cells

    Ismail, A. F., Oskay Halacli, S., Babteen, N., De Piano, M., Martin, T. A., Jiang, W. G., Shamim Khan, M., Dasgupta, P. & Wells, C. M., 1 Apr 2017, In : Biochemical Journal. 474, 8, p. 1333-1346

    Research output: Contribution to journalArticle

  31. Fluorescence Lifetime Imaging

    Suhling, K., Hirvonen, L., Levitt, J., Chung, P-H., Tregidgo, C., Rusakov, D. A., Zheng, K., Ameer-Beg, S., Poland, S., Pereira Coelho, S. C., Henderson, R. & Krstajic, N., 29 Mar 2017, Handbook of Photonics for Biomedical Engineering. Springer Netherlands, p. 353-405 53 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  32. Functional in vivo imaging using fluorescence lifetime light-sheet microscopy

    Mitchell, C. A., Poland, S. P., Seyforth, J., Nedbal, J., Gelot, T., Huq, T., Holst, G., Knight, R. D. & Ameer-Beg, S. M., 23 Mar 2017, In : Optics Letters. 42, 7, p. 1269-1272 4 p.

    Research output: Contribution to journalArticle

  33. Differential role for PAK1 and PAK4 during the invadopodia lifecycle

    Nicholas, N., Pipili, A., Lesjak, M. S. & Wells, C. M., 17 Mar 2017, In : Small GTPases. p. 1-7 7 p.

    Research output: Contribution to journalArticle

  34. RORγt+ innate lymphoid cells promote lymph node metastasis of breast cancers

    Irshad, S., Flores-Borja, F., Lawler, K., Monypenny, J., Evans, R., Male, V., Gordon, P., Cheung, A., Gazinska, P., Noor, F., Wong, F., Grigoriadis, A., Fruhwirth, G. O., Barber, P. R., Woodman, N., Patel, D., Rodriguez-Justo, M., Owen, J., Martin, S. G., Sarah, E. P. & 13 others, Cheryl, E. G., Poland, S. P., Ameer-Beg, S., McCaughan, F., Carlin, L. M., Hasan, U., Withers, D. R., Lane, P., Vojnovic, B., Quezada, S. A., Ellis, P., Tutt, A. N. J. & Ng, T., 1 Mar 2017, In : Cancer Research. 77, 5, p. 1083-1096 14 p.

    Research output: Contribution to journalArticle

  35. Anti-folate receptor-α IgE but not IgG recruits macrophages to attack tumors via TNFa/MCP-1 signaling

    Josephs, D. H., Bax, H. J., Dodev, T., Georgouli, M., Nakamura, M., Pellizzari, G., Saul, L., Karagiannis, P., Cheung, A., Herraiz, C., Ilieva, K. M., Correa, I., Fittall, M., Crescioli, S., Gazinska, P., Woodman, N., Mele, S., Chiaruttini, G., Gilbert, A. E., Koers, A. & 21 others, Bracher, M., Selkirk, C., Lentfer, H., Barton, C., Lever, E., Muirhead, G., Tsoka, S., Canevari, S., Figini, M., Montes, A., Downes, N., Dombrowicz, D., Corrigan, C. J., Beavil, A. J., Nestle, F. O., Jones, P. S., Gould, H. J., Sanz-Moreno, V., Blower, P. J., Spicer, J. F. & Karagiannis, S. N., Mar 2017, In : Cancer Research. 77, 5, p. 1127-1141 15 p.

    Research output: Contribution to journalArticle

  36. PAK4 interacts with p85 alpha: Implications for pancreatic cancer cell migration

    King, H., Thillai, K., Whale, A., Arumugam, P., Eldaly, H., Kocher, H. M. & Wells, C. M., 16 Feb 2017, In : Scientific Reports. 7, 42575.

    Research output: Contribution to journalArticle

Previous 1 2 3 4 5 6 7 8 Next

View graph of relations

Search within the list

Refine results

Language

Language

Publication year

Publication year

Full text

Full text

Meeting and poster abstracts

Meeting and poster abstracts

© 2018 King's College London | Strand | London WC2R 2LS | England | United Kingdom | Tel +44 (0)20 7836 5454