Cancer & Pharmaceutical Sciences

2024

35 Validation of published radiomics model to determine if CT parameters predict Programmed Death Ligand 1 expression in Non-Small Cell Lung Cancer

Manickavasagar, T., Horst, C., O'Shea, R., Hughes, D., Josephides, E., Nonaka, D., Bille, A., Eleni, K., Cook, G. & Goh, V., Apr 2024, In: Lung Cancer. 190, 107596.

Research output: Contribution to journal › Meeting abstract › peer-review

A Phase II Study Evaluating PD-L1 Expression in Non-Small Cell Lung Cancer Using [99mTc]NM-01 SPECT/CT, a Technetium-99m Radiolabeled Anti-PD-L1 Single Domain Antibody

Chand, G., Hughes, D., Meszaros, L., Ting, H. H., Moore, A., Johnson, J., Adamson, K., Bailey, D., Spicer, J., Minchom, A. & Cook, G., Jun 2024, In: Journal of Nuclear Medicine. 65 (supplement 2), 241489.

Research output: Contribution to journal › Meeting abstract › peer-review

PD-L1 imaging with [99mTc]NM-01 SPECT/CT predicts early metabolic response to pembrolizumab with or without chemotherapy in advanced non-small cell lung cancer (NSCLC): results from the PECan study.

Hughes, D., Chand, G., Moore, A. E. B., Meszaros, L. K., Johnson, J., Adamson, K., Bailey, D., Tegala, R., Edmonds, S., Ndagire, S., Gennatas, S., Georgiou, A., Ghosh, S., Eleni, K., Josephs, D., McLean, E., Ting, H. H., Spicer, J., Goh, V. & Cook, G., Jun 2024, In: Journal of Nuclear Medicine. 65 (supplement 2), 241338.

Research output: Contribution to journal › Meeting abstract › peer-review

2022

SPECT/CT using [99mTc]-labeled anti-programmed death-ligand 1 (PD-L1) single-domain antibody (NM-01) to predict response to immune checkpoint inhibition in non-small cell lung cancer: preliminary results from the PD-L1 Expression in Cancer (PECan) study.

Hughes, D., Chand, G., Meszaros, L., Adamson, K., Johnson, J., Bailey, D., Gibson, V., Edmonds, S., Georgiou, A., Karapanagiotou, E., Josephs, D., McLean, E., Ting, H. H., Spicer, J., Goh, V. & Cook, G., 1 Jun 2022, In: Journal of Nuclear Medicine. 63 (supplement 2), 2594.

Research output: Contribution to journal › Meeting abstract › peer-review

2020

Low FODMAP diet & prebiotic β-galactooligosaccharides improve irritable bowel syndrome and response to low FODMAP is predicted by urine and faecal metabolites: A randomised controlled trial

Wilson, B., Rossi, M., Kanno, T., Hough, R., Probert, C., Parkes, G., Anderson, S., Irving, P., Mason, A. J., Lomer, M. C. & Whelan, K., 2020, In: Proceedings of the Nutrition Society. 79, OCE1, E19.

Research output: Contribution to journal › Meeting abstract › peer-review

5 Citations (Scopus)

2018

A brief physiotherapist-led behaviour-change intervention to facilitate walking in older people with peripheral arterial disease: protocol for a randomised controlled trial

Galea Holmes, M., Weinman, J. A., Peacock, J. L., Eddy, S., Moderai, B., Patel, S., Fisher, G., Sackley, C. M. & Bearne, L. M., 6 Feb 2018, (Accepted/In press) Clinical Rehabilitation.

Research output: Chapter in Book/Report/Conference proceeding › Meeting abstract › peer-review

A systematic review of neo-adjuvant radiotherapy in the treatment of breast cancer: BASO ∼ The Association for Cancer Surgery Annual Scientific Conference and the NCRI Cancer Conference – 5th – 8th November 2017Abstract BookAnnual Scientific Conference and the NCRI Cancer Conference – 5th – 8th November 2017

Ahmed, M. & Douek, M., Mar 2018, In: European Journal of Surgical Oncology. 44, Supplement 1, p. S26

Research output: Contribution to journal › Meeting abstract › peer-review

Could Women with Biopsy Proven Lymph Node Positive Breast Cancer and Response to Primary Chemotherapy Avoid Axillary Lymph Node Clearance?

Germanou, S., Ruhe Chowdhury, M. H., Thillai, K., Lucey, A., Michalarea, V., Mera, A., Karapanagiotou, E., Sandri, I. & Mansi, J., Jun 2018, In: Clinical Oncology. 30, 6, p. e43-e44

Research output: Contribution to journal › Meeting abstract › peer-review

Development and validation of the non-technical skills for urological surgeons (NoTSUS) ureteroscopy scenario curriculum

Aydin, A., Brunckhorst, O., Raison, N., Brewin, J., Mcilhenny, C., Al-jabir, A., Aya, H., Dar, F., Iqbal, M., Lovegrove, C., Shabbir, M., Brouwers, T., Palou Redorta, J., Khan, M., Dasgupta, P. & Ahmed, K., 1 Mar 2018, In: EUROPEAN UROLOGY SUPPLEMENTS. 17, 2, p. e674-e675

Research output: Contribution to journal › Meeting abstract › peer-review

F228. EFFECTIVENESS OF PALIPERIDONE PALMITATE VS OTHER LONG-ACTING INJECTABLE (LAI) ANTIPSYCHOTICS – AN ELECTRONIC CASE REGISTER STUDY

Patel, R., Chesney, E., Taylor, M. J., Taylor, D. M. & McGuire, P., 1 Apr 2018, In: Schizophrenia Bulletin. 44, suppl_1, p. S310-S311 2 p.

Research output: Contribution to journal › Meeting abstract › peer-review

Open Access

Feasibility and acceptability of a brief physiotherapist-led behaviour-change intervention to facilitate walking in older people with intermittent claudication.

Galea Holmes, M., Weinman, J. A. & Bearne, L. M., 6 Feb 2018, (Accepted/In press) Clinical Rehabilitation.

Research output: Chapter in Book/Report/Conference proceeding › Meeting abstract › peer-review

Giant juvenile fibroadenoma in a 12-year-old girl treated with breast conserving surgery: Largest reported case in the UK: Association of Surgeons in Training 2018 Conference

Stringfellow, T. & Douek, M., 2018, In: International Journal Of Surgery. 55, p. S17

Research output: Contribution to journal › Meeting abstract › peer-review

2017

Cancer Clinical Practice Guidelines: Evaluation of ESMO, NICE and SIGN diversity

Pallari, E., Fox, A. & Lewison, G. R. G., 14 Sept 2017, In: Annals of Oncology.

Research output: Contribution to journal › Meeting abstract › peer-review

Control of the sympathetic nervous system by TRPV1 in the regulation of body temperature

Alawi, K., Aubdool, A., Liang, L., Wilde, E., Vepa, A., Psefteli, P.-M., Brain, S. & Keeble, J., 27 Oct 2017, In: Neuropeptides. 65, p. 131-132 2 p.

Research output: Contribution to journal › Meeting abstract › peer-review

DISCOVERY AND VALIDATION OF MULTIMODAL BIOMARKER SIGNATURES RELATING TO ALZHEIMER'S DISEASE PATHOLOGY AND PROGRESSION: 2017 Abstract Supplement

Westwood, S., Hye, A., Lleó, A., Nevado-Holgado, A. J., Baird, A. L., Wallin, A., Leslie, A., Jimenez, B., Liu, B. Y., Legido-Quigley, C., Dima, D., Ruvolo, D., Holmes, E., D'Hondt, E., Westman, E., Barkhof, F., Frisoni, G. B., Zetterberg, H., Bos, I. & Pearce, J. & 27 others, Streffer, J., Molinuevo, J. L., Popp, J., Bertram, L., Whiley, L., Maslen, L., Gomez-Romero, M., David, M., Lewis, M., Kurbatova, N., Ashton, N. J., Voyle, N., Kowalczyk, O., Martinez-Lage, P., Proitsi, P., Scheltens, P., Visser, P. J., Dobson, R. J., Vandenberghe, R., Engelborghs, S., Vos, S. J. B., Snowden, S. G., Athersuch, T., Ashby, T., Kimhofer, T., Verachtert, W. & Lovestone, S., Jul 2017, In: Alzheimer's & Dementia. 13, 7, Supplement, p. P174-P175

Research output: Contribution to journal › Meeting abstract › peer-review

OA 02.01 Randomized Phase II Study of Anetumab Ravtansine or Vinorelbine in Patients with Metastatic Pleural Mesothelioma: IASLC 18th World Conference on Lung CancerIASLC 18th World Conference on Lung Cancer

Kindler, H. L., Novello, S., Fennell, D., Blumenschein, G., Bearz, A., Ceresoli, G., Aerts, J., Spicer, J., Taylor, P., Greystoke, A., Nackaerts, K., Calabro, L., Burgers, S., Jennens, R., Sporchia, A., Walter, A., Siegel, J., Childs, B., Elbi, C. & Hassan, R., Nov 2017, In: Journal Of Thoracic Oncology. 12, 11, Supplement 2, p. S1746

Research output: Contribution to journal › Meeting abstract › peer-review

42 Citations (Scopus)

Oligomerization of the Epidermal Growth Factor Receptor Organizes Kinase-Active Dimers into Competent Signaling Platforms

Needham, S. R., Zanetti-Domigues, L. C., Arkhipov, A., Mysore, V. P., Korovesis, D., Roberts, S. K., Tynan, C. J., Rolfe, D. J., Hirsch, M., Lajevardipour, A., Clayton, A. H. A., Parker, P. J., Shan, Y., Shaw, D. E. & Martin-Fernandez, M. L., 3 Feb 2017, In: Biophysical Journal. 112, 3, Supplement 1, p. 26a-27a

Research output: Contribution to journal › Meeting abstract › peer-review

Outcomes of Patients with Pre-Existing Invasive Fungal Disease Undergoing Allogeneic Haematopoietic Stem Cell Transplantation — 5 Years Single Centre Experience

Mehra, V., Barnwell, E., Boczek, U., Widya, S., Raj, K., De Lavallade, H., McLornan, D., Potter, V., Rice, C., Lim, C., Kenyon, M., Bisquera, A., Marsh, J., Ceesay, M. M., Pagliuca, A. & Mufti, G., 7 Dec 2017, In: Blood. 130, Suppl 1, p. 3216 1 p.

Research output: Contribution to journal › Meeting abstract › peer-review

P 011 - Mycosporine-like amino acid activation of the Keap1-Nrf2 pathway: Abstracts of the OCC World Congress and Annual SFRR-E Conference 2017 Metabolic Stress and Redox Regulation Berlin, Germany 21-23 June 2017

Gacesa, R., Barlow, D., Dunlap, W., Georgakopoulos, N., Wells, G. & Long, P., 1 Jul 2017, In: Free Radical Biology and Medicine. 108, Supplement 1, p. S21

Research output: Contribution to journal › Meeting abstract › peer-review

Preclinical modeling of myelodysplastic syndromes

Mian, S., Rouault-pierre, K., Goulard, M., Fenaux, P., Dosquet, C., Mufti, G. & Bonnet, D., 1 Sept 2017, In: Experimental Hematology. 53, p. S78

Research output: Contribution to journal › Meeting abstract › peer-review

Serum inflammatory markers in relation to prostate cancer severity and death

Crawley, D., Williams, R., Garmo, H., Holmberg, L., Stattin, P., Malmstrom, H., Lambe, M., Hammar, N., Walldius, G., Robinson, D., Jungner, I. & Van Hemelrijck, M., Nov 2017, In: European Journal of Surgical Oncology. 43, 11, p. 2223-2224 2 p.

Research output: Contribution to journal › Meeting abstract › peer-review

Stenting Across the Inguinal Ligament in Post Thrombotic Syndrome Using Nitinol Venous Stents: One-year Patency Outcomes

Saha, P., Gwozdz, A. M., El-Sayed, T., Karunanithy, N., Breen, K., Hunt, B. J., Cohen, A. T., McDonald, V., Smith, A. & Black, S., 26 Oct 2017, (E-pub ahead of print) In: European Journal of Vascular and Endovascular Surgery. 54, 5, p. 664 1 p.

Research output: Contribution to journal › Meeting abstract › peer-review

Transport of TRPV1 ligands through the blood-brain barrier

McNickle, L., Brown, R., Keeble, J., Sekhar, G. & Thomas, S., 27 Oct 2017, (E-pub ahead of print) In: Neuropeptides. 65, p. 132 1 p.

Research output: Contribution to journal › Meeting abstract › peer-review

2016

483 Alternative activation of cutaneous B cells and IgG antibody subclass polarisation in melanoma: ESDR 2016 Annual Meeting Abstract SupplementEuropean Society for Dermatological Research (ESDR) Annual Meeting

Saul, L., Karagiannis, P., Ilieva, K. M., Correa, I., Geh, J., Healy, C., Spicer, J. F., Nestle, F. O., Lacy, K. E. & Karagiannis, S. N., Sept 2016, In: Journal of Investigative Dermatology. 136, 9, Supplement 2, S243.

Research output: Contribution to journal › Meeting abstract

A MODULE-BASED REGULATORY PROGRAM ANALYSIS IDENTIFIES ASSOCIATION BETWEEN EXO1 AND MAP-KINASE INACTIVATION IN TRIPLE NEGATIVE BREAST CANCERS

Quist, J. S., Mirza, H. B., Cheang, M., Telli, M., Tutt, A. N. J. & Grigoriadis, A., 2016, (Accepted/In press) In: NCRI Conference.

Research output: Contribution to journal › Meeting abstract › peer-review

Copy Number Aberration-induced Gene Breakage Analysis Identifies Recurrent FOXP1 Fusions in Breast Cancer

Mohd Noor, A. B., Maguire, S., Mirza, H. B., Quist, J. S., Watkins, J., Gillett, C. E., Tutt, A. N. J., Natrajan, R. & Grigoriadis, A., 2016, In: NCRI Conference.

Research output: Contribution to journal › Meeting abstract › peer-review

Exploring full-blown psychotic experiences in ‘non-need for care’ populations: Findings from the UNIQUE Study: Abstracts of the 24rd European Congress of Psychiatry

Peters, E., Ward, T., Jackson, M., Morgan, C., Mc Guire, P., Woodruff, P. & Garety, P., Mar 2016, In: European Psychiatry. 33, Supplement, p. S48

Research output: Contribution to journal › Meeting abstract › peer-review

Histological Classification of Pancreatic Neuroendocrine Tumors: Optimizing the Ki67 Range for Grade of Tumors

Mills, L., Ramage, J. K., Prachalias, A., Srinivasan, P., Menon, K., Quaglia, A., Vivian, G., Heaton, N., Sarker, D., Ross, P. & Srirajaskanthan, R., Mar 2016, In: Pancreas. 45, 3, p. 479-479

Research output: Contribution to journal › Meeting abstract › peer-review

Pre-Emptive Donor Lymphocyte Infusion Corrects Deficiencies in the T-Cell Repertoire after Allogeneic Haematopoietic Stem Cell Transplantation with Lymphocyte-Depletion for Acute Myeloid Leukaemia and Myelodysplastic Syndromes: Abstracts from the 2016 BMT Tandem Meetings

Barber, L. D., Al Rakhayes, M., Golding, J., Feliu, J., Perez-Abellan, P., Floro, L., Clay, J., Pagliuca, A., Farzaneh, F., Krishnamurthy, P., Potter, V. & Mufti, G. J., 18 Mar 2016, (E-pub ahead of print) In: BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. 22, 3, Supplement, p. S150

Research output: Contribution to journal › Meeting abstract › peer-review

Psychological determinants of medication adherence in stroke survivors: a systematic review of observational studies

Crayton, E. F., Fahey, M. P., Ashworth, M., Besser, S. J., Weinman, J. A. & Wright, A. J., 2016, In: European Health Psychologist. 18 Supp, 1 p.

Research output: Contribution to journal › Meeting abstract › peer-review

2015

A physiotherapist-led behaviour-change intervention targeting walking in people with intermittent claudication: a feasibility and acceptability study.

Galea Holmes, M., Weinman, J. A. & Bearne, L. M., 15 Oct 2015, Physiotherapy UK, 16–17 October 2015, Liverpool, UK.

Research output: Chapter in Book/Report/Conference proceeding › Meeting abstract › peer-review

Attractor reconstruction of blood pressure waveforms: a non-biased approach to the early diagnosis of shock

Nandi, M., Mistry, H., Charlton, P., Christie, M. I. & Aston, P., Sept 2015, Congress of the European Shock Society in conjunction with: : 14th International Conference on Complex Acute Illness.

Research output: Chapter in Book/Report/Conference proceeding › Meeting abstract

Novel Iron Chelating Probes for the Specific Monitoring of Mitochondrial Iron Levels

Abbate, V., Reelfs, O. S., Pourzand, C. & Hider, R. C., Oct 2015, In: Journal of World Mitochondria Society. 1, 1, p. 92-92

Research output: Contribution to journal › Meeting abstract › peer-review

Novel Mitochondria-Targeted Peptide Iron Chelators for Iron Sensing and Protection Against Oxidative Stress-Indiced Mitochondrial Damage

Abbate, V., Reelfs, O. S., Pourzand, C. & Hider, R. C., Oct 2015, In: Journal of World Mitochondria Society. 1, 1, p. 65-65

Research output: Contribution to journal › Meeting abstract › peer-review

Pancreatic Neuroendocrine Incidentalomas: When Is Surgery in the Patient's Best Interests?

Mills, L., Ramage, J., Prachalias, A., Srinivasan, P., Menon, K., Quaglia, A., Vivian, G., Heaton, N., Sarker, D., Ross, P., Basuroy, R. & Srirajaskanthan, R., 2015, In: Neuroendocrinology. 102, 1-2, p. 143-143

Research output: Contribution to journal › Meeting abstract › peer-review

Patients Prescribed Warfarin with Poor Time in Therapeutic Range (TTR) Have Different Beliefs about Their Illness and Anticoagulation Therapy Compared to Those with a Good TTR - Early Results from the Switching Study

Abdou, J. K., Patel, J. P., Vadher, B., Brown, A., Roberts, L., Patel, R. K., Arya, R. & Auyeung, W. Y. V., 3 Dec 2015, In: Blood. 126, 23, p. 2331 1 p.

Research output: Contribution to journal › Meeting abstract

THE MANAGEMENT OF INCIDENTALLY DIAGNOSED PANCREATIC NEUROENDOCRINE LESIONS: A NEW TOOL TO EVALUATE RISK OF MALIGNANCY

Mills, L., Ramage, J., Prachalias, A., Srinivasan, P., Menon, K., Quaglia, A., Heaton, N., Sarker, D., Ross, P., Basuroy, R. & Srirajaskanthan, R., Jun 2015, In: Gut. 64, p. A306-A306

Research output: Contribution to journal › Meeting abstract › peer-review

5 Citations (Scopus)

2014

Abstract 1630: C8-linked pyrrolobenzodiazepine (pbd)-benzofused conjugates with low-picomolar in vitro cytotoxicity

Mantaj, J., Jackson, P., Pepper, C., Thurston, D. & Rahman, K., 1 Oct 2014, Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 1 p. 1630. (Cancer Research; vol. 74, no. S19).

Research output: Chapter in Book/Report/Conference proceeding › Meeting abstract › peer-review

A Meta-Analysis of the Harms Associated with the Novel Oral Anticoagulants (NOACs) for Stroke Prevention in Atrial Fibrillation (AF) and the Treatment of Venous Thromboembolism (VTE) in the Elderly

Sharma, M., Cornelius, V. R., Patel, J. P., Davies, J. G. & Molokhia, M., Oct 2014, In: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 23, S1, p. 225-226 2 p., 428.

Research output: Contribution to journal › Meeting abstract › peer-review

Aryl hydrocarbon receptor ligands benzo[a]pyrene, ellipticine and Sudan I are potent inducers of cytochrome b5 in rats

Mrizova, I., Moserova, M., Dracinska, H., Arlt, V. M., Frei, E. & Stiborova, M., 10 Sept 2014, In: Toxicology Letters. 229, Supplement, p. S151-S151 1 p.

Research output: Contribution to journal › Meeting abstract › peer-review

Comprehending the inexplicable: qualitative accounts of black Caribbean and white british people severely affected by multiple sclerosis

Koffman, J., Goddard, C., Silber, E., Burman, R., Shaw, P., Barnes, F., Speck, P. & Higginson, I., Mar 2014, In: BMJ Supportive & Palliative Care. 4 , Suppl 1, p. A20 1 p., P 013.

Research output: Contribution to journal › Meeting abstract › peer-review

crp and granulocyte-to-lymphocyte ratio as predictors of breast cancer death in american non-institutionalized women.

Wulaningsih, W., Holmberg, L. & Van Hemelrijck, M., May 2014, In: Annals of Oncology. 25, Suppl 1, p. i9 1 p., 24P.

Research output: Contribution to journal › Meeting abstract › peer-review

Open Access

53 Citations (Scopus)

Dicoumarol inhibits NAD(P)H:quinone oxidoreductase-mediated formation of aristolochic acid-DNA adducts in vitro whereas increases their generation in rats in vivo

Barta, F., Levova, K., Frei, E., Arlt, V. M., Schmeiser, H. H. & Stiborova, M., 10 Sept 2014, In: Toxicology Letters. 229, p. S146-S146 1 p.

Research output: Contribution to journal › Meeting abstract › peer-review

Differential effects of ambient diesel carcinogens on inflammation and DNA damage response in cells relevant for lung toxicity

Longhin, E., Ovrevik, J., Gualtieri, M., Totlandsdal, A., Mollerup, S., Ask, K., Arlt, V. M., Schwarze, P. E., Camatini, M. & Holme, J. A., 10 Sept 2014, In: Toxicology Letters. 229, Supplement, p. S25-S25 1 p.

Research output: Contribution to journal › Meeting abstract › peer-review

17 Citations (Scopus)

Do behaviour-change techniques increase walking in patients with intermittent claudication? A systematic review

Galea Holmes, M., Weinman, J., White, C. & Bearne, L., 2014, British Psychological Society Division of Health Psychology Annual Conference.

Research output: Chapter in Book/Report/Conference proceeding › Meeting abstract › peer-review

Engineered IgE antibodies recognising tumour associated antigens: a paradigm for activating immune effector functions against cancer

Karagiannis, S. N., Josephs, D. H., Bax, H., Karagiannis, P., Saul, L., Dodev, T., Blower, P., Beavil, A., Gould, H. & Spicer, J., Nov 2014, International Journal of Molecular Medicine. Supplement 1 ed. Athens, Greece: SPANDIDOS PUBL LTD, POB 18179, ATHENS, 116 10, GREECE, Vol. 34. p. S86-S86 425

Research output: Chapter in Book/Report/Conference proceeding › Meeting abstract

Cancer & Pharmaceutical Sciences

Research output

Search results