Projects per year
Search results
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Finished
Characterising disease mechanisms and tailoring therapies for coronary microvascular dysfunction
Sinha, A. (Primary Investigator), Perera, D. (Co-Investigator) & Webb, A. (Co-Investigator)
1/10/2020 → 30/09/2023
Project: Research
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Establishing invasive physiological thresholds for ischaemia in left main coronary artery disease
Perera, D. (Primary Investigator)
1/04/2020 → 5/11/2022
Project: Research
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Patterns of Multiple Long-Term Vascular Conditions in Lambeth and Southwark
Douiri, A. (Primary Investigator), Wolfe, C. (Co-Investigator), Redwood, S. (Co-Investigator), Stewart, R. (Co-Investigator), McKevitt, C. (Co-Investigator), Curcin, V. (Co-Investigator) & Marshall, I. (Co-Investigator)
1/04/2020 → 30/09/2021
Project: Research
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Studying transforming growth factor-beta-activated kinase (TAK1) thiol-dependent activation and its role in heart failure
Burgoyne, J. (Primary Investigator)
1/02/2020 → 31/01/2023
Project: Research
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A randomised, double-blind, placebo-controlled, cross-over trial of zibotentan in microvascular angina (PRIZE)
Perera, D. (Primary Investigator) & Chiribiri, A. (Co-Investigator)
1/06/2019 → 30/09/2022
Project: Research
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Using protein-protein inhibitors to target p38α during myocardial ischemia
De Nicola, G. (Primary Investigator) & Marber, M. (Co-Investigator)
19/05/2019 → 18/03/2020
Project: Research
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Real-time virtual fractional flow reserve assessment via deep learning
Lee, J. (Primary Investigator), Redwood, S. (Co-Investigator), Patterson, T. (Co-Investigator) & King, A. (Co-Investigator)
1/05/2019 → 30/04/2022
Project: Research
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BHF Research Excellence Award
Shah, A. (Primary Investigator), Botnar, R. (Co-Investigator), Chowienczyk, P. (Co-Investigator), Eaton, P. (Co-Investigator), Garcia-Manyes, S. (Co-Investigator), Gautel, M. (Co-Investigator), Giacca, M. (Co-Investigator), Irving, M. (Co-Investigator), Lamata de la Orden, P. (Co-Investigator), Marber, M. (Co-Investigator), Mayr, M. (Co-Investigator), Otsu, K. (Co-Investigator), Ourselin, S. (Co-Investigator), Parsons, M. (Co-Investigator), Razavi, R. (Co-Investigator), Schnabel, J. (Co-Investigator), Shanahan, C. (Co-Investigator), Xu, Q. (Co-Investigator) & Phinikaridou, A. (Co-Investigator)
1/04/2019 → 31/03/2024
Project: Research
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The biological variability of cardiac myosin-binding protein C (cMyC) and its ability to assist in the early triage of patients with suspected acute myocardial infarction
Marber, M. (Primary Investigator)
1/02/2019 → 31/01/2021
Project: Research
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Microvascular Inflammation in heart failure with preserved ejection fraction (HFpEF)
Redwood, S. (Primary Investigator), Marber, M. (Co-Investigator) & Allen, C. (Co-Investigator)
1/01/2019 → 31/12/2021
Project: Research
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Thiol-disulfide redox switches in protein kinases and their role in cardiovascular health and disease
Eaton, P. (Primary Investigator), Francois, A. (Co-Investigator) & Prysyazhna, O. (Co-Investigator)
1/05/2018 → 30/04/2023
Project: Research
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Evaluation of a novel physiological biomarker of hibernation in ischaemic left ventricular dysfunction
Perera, D. (Primary Investigator) & Ryan, M. (Co-Investigator)
1/03/2018 → 28/02/2021
Project: Research
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Furthering our understanding of PKGIα in cardiovascular health and disease
Eaton, P. (Primary Investigator), Prysyazhna, O. (Co-Investigator), Cho, H. (Co-Investigator) & Francois, A. (Co-Investigator)
1/03/2018 → 28/02/2023
Project: Research
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Myeloperoxidase inhibition: a novel approach to treating coronary heart disease
Ferro, A. (Primary Investigator), Barrington, S. (Co-Investigator), Douiri, A. (Co-Investigator) & Redwood, S. (Co-Investigator)
1/01/2018 → 31/12/2020
Project: Research
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Mechanical Unloading and Delayed Reperfusion Promotes Myocardial Recovery after Acute Myocardial Infarction
Perera, D. (Primary Investigator)
NIH National Institutes of Health
1/12/2017 → 30/11/2018
Project: Research
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Assessment of myocardial and coronary physiology during cardiac catheterisation - a novel biomarker to guide revascularisation in ischaemic heart failure
Perera, D. (Primary Investigator) & academic, A. (Co-Investigator)
4/10/2017 → 4/10/2020
Project: Research
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Trans-coronary mapping during cardiac catheterisation - a novel biomarker to guide revascularisation in ischaemic heart failure
Perera, D. (Primary Investigator) & academic, A. (Co-Investigator)
4/10/2017 → 3/10/2020
Project: Research
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Trans-coronary mapping during cardiac catheterisation - a novel biomarker to guide revascularisation in ischaemic heartfailure
Perera, D. (Primary Investigator) & academic, A. (Co-Investigator)
4/10/2017 → 3/10/2020
Project: Research
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Assessment of coronary and myocardial physiology during cardiac catheterisation - a novel biomarker to guide revascularisation in ischaemic heart failure
Perera, D. (Primary Investigator) & academic, A. (Co-Investigator)
4/10/2017 → 4/10/2020
Project: Research
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The Virtual Rat Heart Bioassay
Niederer, S. (Primary Investigator), Curtis, M. (Co-Investigator) & Shattock, M. (Co-Investigator)
2/10/2017 → 1/10/2020
Project: Research
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Studying novel modes of autophagy regulation and their roles in heart failure
Burgoyne, J. (Primary Investigator)
1/10/2017 → 20/07/2021
Project: Research
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The Na/K ATPase in cardiovascular health and disease
Shattock, M. (Primary Investigator)
1/10/2017 → 30/09/2022
Project: Research
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The Na/K ATPase in cardiovascular health and disease
Shattock, M. (Primary Investigator), Aksentijevic, D. (Co-Investigator), Basalay, M. (Co-Investigator) & Tokar, S. (Co-Investigator)
1/10/2017 → 30/06/2022
Project: Research
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Non-invasive Differentiation of Microvascular Disease from CAD by Perfusion CMR: Validation Against Invasive Indices of Microvascular Function.
Chiribiri, A. (Primary Investigator), Ismail, T. (Co-Investigator), Marber, M. (Co-Investigator) & Redwood, S. (Co-Investigator)
1/09/2017 → 31/08/2020
Project: Research
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An investigation of the potential therapeutic effects of Sulforadex in Noonan syndrome
Eaton, P. (Primary Investigator) & Cho, H. (Co-Investigator)
1/09/2017 → 31/08/2020
Project: Research
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Cardiac Myosin-Binding Protein C (cMyC) in myocardial infarction
Marber, M. (Primary Investigator)
1/08/2017 → 31/07/2020
Project: Research
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Oxidative Signalling and DNA Hypomethylation: Endogenous Regulation of Tumour Epigenetics
Eaton, P. (Primary Investigator) & Switzer, C. (Co-Investigator)
1/07/2017 → 30/06/2022
Project: Research
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PKG-activating drugs as a novel therapy for hypertension
Eaton, P. (Primary Investigator) & Cho, H. (Co-Investigator)
1/07/2017 → 30/09/2018
Project: Research
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A novel mode for regulating autophagy and its role in age-related cardiovascular disease
Burgoyne, J. (Primary Investigator)
1/07/2017 → 30/06/2020
Project: Research
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Left main coronary Evaluation by Fractional flow reserve To guide Medical therapy AndINtervention (LEFT MAIN)
Perera, D. (Primary Investigator) & Pennington, M. (Co-Investigator)
1/07/2017 → 30/06/2022
Project: Research
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Furthering our understanding of the redox regulation of Protein Kinase A in the cardiovascular system
Eaton, P. (Primary Investigator) & Prysyazhna, O. (Co-Investigator)
1/07/2017 → 30/09/2020
Project: Research
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Activation of soluble Epoxide Hydrolase by intra-protein disulfide formation - role in regulating cardiovascular function in health and disease
Charles, B. (Primary Investigator) & Eaton, P. (Co-Investigator)
1/07/2017 → 30/06/2022
Project: Research
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Investigation of TLR4-Protein Kinase Cε Signalling in the Inhibition of Cardiac Myofibroblasts.
Heads, R. (Primary Investigator)
5/06/2017 → 4/06/2020
Project: Research
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Targeting the repair and regeneration of the damaged and aged heart
Ellison, G. (Primary Investigator), Oakey, R. (Co-Investigator) & Shattock, M. (Co-Investigator)
1/05/2017 → 30/04/2022
Project: Research
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NIHR Biomedical Research Centre. Funding for Financial Years 2017/18, 2018/19
Wolfe, C. (Primary Investigator), Parsons, M. (Primary Investigator), Gould, H. (Primary Investigator), Corrigan, C. (Primary Investigator), Greenough, A. (Primary Investigator), Peakman, M. (Primary Investigator), Vyse, T. (Primary Investigator), Antoniou, M. (Primary Investigator), Oakey, R. (Primary Investigator), McGrath, J. (Primary Investigator), Karagiannis, S. (Primary Investigator), Barker, J. (Primary Investigator), Flohr, C. (Primary Investigator), Tziotzios, C. (Primary Investigator), Whittaker, S. (Primary Investigator), Spector, T. (Primary Investigator), Watt, F. (Primary Investigator), Hayday, A. (Primary Investigator), Spencer, J. (Primary Investigator), Cope, A. (Primary Investigator), Malim, M. (Primary Investigator), Martin Serrano, J. (Primary Investigator), Edgeworth, J. (Primary Investigator), Cason, J. (Primary Investigator), Lord, G. (Primary Investigator), Dorling, A. (Primary Investigator), Sacks, S. (Primary Investigator), Sanchez Fueyo, A. (Primary Investigator), Lombardi, G. (Primary Investigator), Ostermann, M. (Primary Investigator), Shah, A. (Primary Investigator), Marber, M. (Primary Investigator), Mayr, M. (Primary Investigator), Chowienczyk, P. (Primary Investigator), Wells, C. (Primary Investigator), Grigoriadis, A. (Primary Investigator), Sawyer, E. (Primary Investigator), Maher, J. (Primary Investigator), Tribe, R. (Primary Investigator), Ilic, D. (Primary Investigator), Poston, L. (Primary Investigator), Rutherford, M. (Primary Investigator), Gee, T. (Primary Investigator), Blower, P. (Primary Investigator), Edwards, D. (Primary Investigator), Sharpe, P. (Primary Investigator), Streit, A. (Primary Investigator), Naglik, J. (Primary Investigator), Tavassoli, M. (Primary Investigator) & McNaughton, P. (Primary Investigator)
NIHR National Institute For Health & Care Research
1/04/2017 → 31/03/2022
Project: Research
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Autonomic conflict and sudden cardiac death
Shattock, M. (Primary Investigator) & Winter, J. (Co-Investigator)
1/04/2017 → 30/03/2020
Project: Research
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To what extent can PKD-induced phosphorylation of cardiac myofibrils correct the dysfunction of myofibril contraction in the failing human heart
Kentish, J. (Primary Investigator), Avkiran, M. (Co-Investigator) & Sun, Y.-B. (Co-Investigator)
1/03/2017 → 28/02/2019
Project: Research
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Studying transforming growth factor-beta-activated kinase (TAK1) thiol-dependent activation and its role in heart failure
Burgoyne, J. (Primary Investigator)
1/02/2017 → 1/02/2020
Project: Research
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Biological consequences of S-Nitrosylation
Eaton, P. (Primary Investigator) & Switzer, C. (Co-Investigator)
7/01/2017 → 30/06/2020
Project: Research
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MICA: Identification of novel Sulforaphane molecular targets in human basal-like breast cancer
Eaton, P. (Primary Investigator) & Switzer, C. (Co-Investigator)
1/01/2017 → 31/12/2020
Project: Research
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Prediction of functional recovery after CABG using combined high-resolution quantitative assessment of myocardial ischaemia and scar
Chiribiri, A. (Primary Investigator) & Perera, D. (Co-Investigator)
1/01/2017 → 31/12/2019
Project: Research
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Autonomic conflict and sudden cardiac death
Shattock, M. (Primary Investigator) & Winter, J. (Co-Investigator)
1/01/2017 → 31/12/2019
Project: Research
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Development of new hypoxia-avid PET agents for the imaging of chronic cardiovascular disease
Southworth, R. (Primary Investigator), Blower, P. (Co-Investigator), Clark, J. (Co-Investigator) & Eykyn, T. (Co-Investigator)
1/01/2017 → 31/12/2019
Project: Research
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Developing inhibitors of the p38a-TAB1 protein interaction
De Nicola, G. (Primary Investigator) & Marber, M. (Co-Investigator)
1/01/2017 → 30/06/2018
Project: Research
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A Randomised tRial of Expedited transfer to a cardiac arrest centre for non-ST elevation out of hospital cardiac arrest. The ARREST trial. ISRCTN 96585404.
Redwood, S. (Primary Investigator), McCrone, P. (Co-Investigator), Mosweu, I. (Co-Investigator), Patterson, T. (Co-Investigator) & Perera, D. (Co-Investigator)
1/01/2017 → 30/04/2023
Project: Research
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King’s NMR Facility for structural biology, metabolic profiling and drug discovery
Conte, M. (Primary Investigator), Avkiran, M. (Co-Investigator), Blower, P. (Co-Investigator), Dodding, M. (Co-Investigator), Eaton, P. (Co-Investigator), Gautel, M. (Co-Investigator), Irving, M. (Co-Investigator), Malim, M. (Co-Investigator), Marber, M. (Co-Investigator), Mayr, M. (Co-Investigator), McDonnell, J. (Co-Investigator), Otsu, K. (Co-Investigator), Pastore, A. (Co-Investigator), Pfuhl, M. (Co-Investigator), Poston, L. (Co-Investigator), Shah, A. (Co-Investigator), Shanahan, C. (Co-Investigator), Shattock, M. (Co-Investigator) & Williamson, C. (Co-Investigator)
BHF British Heart Foundation, Wellcome Trust
1/01/2017 → 31/12/2021
Project: Research