Centre for Affective Disorders

Research output

Research output per year 1987 2013 2015 2016 2017 2018 2019 2020 2021 2022 2023 2025

• 114823 Citations
• 1354 Article
• 180 Meeting abstract
• 160 Review article
• 64 Editorial
• 229 More
  • 49 Letter
  • 45 Literature review
  • 43 Chapter
  • 33 Comment/debate
  • 19 Conference paper
  • 11 Poster abstract
  • 11 Other contribution
  • 6 Meeting Abstract
  • 4 Book
  • 4 Book/Film/Article review
  • 2 Report
  • 1 Short survey
  • 1 Preprint

Research output per year

Research output per year

Search results

• 2016

  Is chronic fatigue syndrome an inflammatory disorder?

  Strawbridge, R., Sartor, M.-L., Young, A. H. & J Cleare, A., Jun 2016, In: Journal of Psychosomatic Research. 85, p. 82 1 p.

  Research output: Contribution to journal › Literature review › peer-review

  Open Access

  File
  252 Downloads (Pure)
• 2014

  HPA axis and aging in depression: Systematic review and meta-analysis

  Murri, M. B., Pariante, C., Mondelli, V., Masotti, M., Atti, A. R., Mellacqua, Z., Antonioli, M., Ghio, L., Menchetti, M., Zanetidou, S., Innamorati, M. & Amore, M., Mar 2014, In: Psychoneuroendocrinology. 41, N/A, p. 46-62 17 p., N/A.

  Research output: Contribution to journal › Literature review › peer-review

  • Aging 100%
  • Meta-Analysis 100%
  • Systematic Review 100%
  • Cortisol 66%
  • Corticotropin-Releasing Hormone 33%
  265 Citations (Scopus)

• Modulation of Adult Hippocampal Neurogenesis by Early-Life Environmental Challenges Triggering Immune Activation

  Musaelyan, K., Egeland, M., Fernandes, C., Pariante, C. M., Zunszain, P. A. & Thuret, S., 2014, In: Neural Plasticity. 10 p., 194396.

  Research output: Contribution to journal › Literature review › peer-review

  Open Access

  • Psychiatric Disorder 100%
  • Infant 50%
  • Schizophrenia 50%
  • Behavior (Neuroscience) 50%
  • Hippocampus 50%
  39 Citations (Scopus)
• 2013

  Conceptualising and measuring the well-being of people with psychosis: Systematic review and narrative synthesis

  Schrank, B., Bird, V., Tylee, A., Coggins, T., Rashid, T. & Slade, M., Sept 2013, In: Social Science & Medicine. 92, p. 9-21 13 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Narrative 100%
  • Systematic Review 100%
  • Conceptual Framework 15%
  • Mental Illness 7%
  • Inclusion 7%
  56 Citations (Scopus)

  2 Downloads (Pure)

• Depression pathogenesis and treatment: what can we learn from blood mRNA expression?

  Hepgul, N., Cattaneo, A., Zunszain, P. A. & Pariante, C. M., 5 Feb 2013, In: BMC Medicine. 11, 1, 13 p., 28.

  Research output: Contribution to journal › Literature review › peer-review

  Open Access

  File

  • Major Depressive Disorder 100%
  • Antidepressant 50%
  • Glucocorticoid Receptor 50%
  • Neuroplasticity 50%
  • Inflammation 50%
  106 Citations (Scopus)

  279 Downloads (Pure)

• From objectivity to subjectivity: conceptualization and measurement of well-being in mental health

  Schrank, B., Riches, S., Coggins, T., Tylee, A. & Slade, M., Oct 2013, In: Cognitive Neuropsychiatry. 3, 5, p. 525-534 10 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Mental Health 100%
  • Mental Illness 14%
  • Positive Psychology 14%
  • Subjective Well-Being 14%
  25 Citations (Scopus)

  238 Downloads (Pure)

• Pituitary gland volume in patients with schizophrenia, subjects at ultra high-risk of developing psychosis and healthy controls: A systematic review and meta-analysis

  Nordholm, D., Krogh, J., Mondelli, V., Dazzan, P., Pariante, C. & Nordentoft, M., Nov 2013, In: Psychoneuroendocrinology. 38, 11, p. 2394-2404 11 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Pituitary Gland 100%
  • Schizotypal Disorder 12%
  59 Citations (Scopus)

• The role of immune genes in the association between depression and inflammation: A review of recent clinical studies

  Bufalino, C., Hepgul, N., Aguglia, E. & Pariante, C. M., Jul 2013, In: Brain Behavior and Immunity. 31, N/A, p. 31-47 17 p., N/A.

  Research output: Contribution to journal › Literature review › peer-review

  • Inflammation 100%
  • Innate Immune System 25%
  • Interleukin-1 25%
  • Enzymes 16%
  • Antidepressant Therapy 16%
  194 Citations (Scopus)

• Vitamin D and psychosis: Mini meta-analysis

  Murri, M. B., Respino, M., Masotti, M., Innamorati, M., Mondelli, V., Pariante, C. & Amore, M., Oct 2013, In: Schizophrenia Research. 150, 1, p. 235-239 5 p., N/A.

  Research output: Contribution to journal › Literature review › peer-review

  • Schizophrenia 100%
  • Psychotic Disorder 100%
  • Meta-Analysis 100%
  • Major Depression 50%
  • Major Depressive Disorder 14%
  93 Citations (Scopus)
• 2012

  Alterations of the amplitude of low-frequency fluctuations in treatment-resistant and treatment-response depression: A resting-state fMRI study

  Guo, W.-B., Liu, F., Xue, Z.-M., Xu, X.-J., Wu, R.-R., Ma, C.-Q., Wooderson, S. C., Tan, C.-L., Sun, X.-L., Chen, J.-D., Liu, Z.-N., Xiao, C.-Q., Chen, H.-F. & Zhao, J.-P., 27 Apr 2012, In: Progress in Neuro-Psychopharmacology & Biological Psychiatry. 37, 1, p. 153 - 160 8 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Treatment-Resistant Depression 100%
  • Brain 42%
  • Cerebellum 28%
  • Visual Memory 28%
  • Brain Network 28%
  157 Citations (Scopus)

• Clinicians' attitudes to depression in Europe: a pooled analysis of Depression Attitude Questionnaire findings

  Haddad, M., Menchetti, M., Walters, P., Norton, J., Tylee, A. & Mann, A., 2012, In: Family Practice. 29, 2, p. 121 - 130 10 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Nurse 100%
  • Occupation (Patient Social Context) 100%
  • Health Practitioner 50%
  • Data Base 50%
  • Primary Medical Care 50%
  27 Citations (Scopus)

• Grey matter differences in bipolar disorder: a meta-analysis of voxel-based morphometry studies

  Selvaraj, S., Arnone, D., Job, D., Stanfield, A., Farrow, T. F. D., Nugent, A. C., Scherk, H., Gruber, O., Chen, X., Sachdev, P. S., Dickstein, D. P., Malhi, G. S., Ha, T. H., Ha, K., Phillips, M. L. & McIntosh, A. M., Mar 2012, In: Bipolar Disorders. 14, 2, p. 135 - 145 11 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Bipolar Disorder 100%
  • Meta-Analysis 100%
  • Gray Matter 100%
  • Brain 33%
  • Temporal Lobe 33%
  219 Citations (Scopus)

• Hypothalamic-pituitary-adrenal axis dysfunction in chronic fatigue syndrome

  Papadopoulos, A. S. & Cleare, A. J., Jan 2012, In: Nature Reviews Endocrinology. 8, 1, p. 22 - 32 11 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Etiology 100%
  • Cognitive Behavioral Therapy 100%
  • Negative Feedback 100%
  • Woman 62%
  • Therapeutic Procedure 62%
  197 Citations (Scopus)

• Stress abnormalities in individuals at risk for psychosis: A review of studies in subjects with familial risk or with "at risk" mental state

  Aiello, G., Horowitz, M., Hepgul, N., Pariante, C. M. & Mondelli, V., Oct 2012, In: Psychoneuroendocrinology. 37, 10, p. 1600-1613 14 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Mental State 100%
  • Vulnerability 66%
  • Adrenocorticotropic Hormone 9%
  128 Citations (Scopus)

• Symptomatic treatment of interferon-α-induced depression in hepatitis C: a systematic review

  Baraldi, S., Hepgul, N., Mondelli, V., Pariante, C. M. & Mondelli, V., Aug 2012, In: Journal of Clinical Psychopharmacology. 32, 4, p. 531-543 13 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Interferon 100%
  • Case Report 50%
  • Antidepressant 16%
  • Amisulpride 16%
  • Anorexia 16%
  50 Citations (Scopus)

• Tiagabine for acute affective episodes in bipolar disorder

  Vasudev, A., Macritchie, K., Rao, S. K., Geddes, J. & Young, A., 12 Dec 2012, In: Cochrane Database of Systematic Reviews. N/A, 12, p. N/A 16 p., CD004694.

  Research output: Contribution to journal › Literature review › peer-review

  • Tiagabine 100%
  • Randomized Controlled Trial 57%
  • Seizure 28%
  • Anxiety 14%
  • Neuroticism 14%
  7 Citations (Scopus)
• 2011

  Glucocorticoids, cytokines and brain abnormalities in depression

  Zunszain, P. A., Anacker, C., Cattaneo, A., Carvalho, L. A. & Pariante, C. M., 29 Apr 2011, In: Progress in Neuro-Psychopharmacology & Biological Psychiatry. 35, 3, p. 722 - 729 8 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Brain Abnormalities 100%
  • Major Depressive Disorder 44%
  • Inflammation 22%
  • Neurodegenerative Disorder 11%
  • Brain 11%
  453 Citations (Scopus)

• Meta-analysis and meta-regression of hypothalamic-pituitary-adrenal axis activity in functional somatic disorders

  Tak, L. M., Cleare, A. J., Ormel, J., Manoharan, A., Kok, I. C., Wessely, S. & Rosmalen, J. G. M., May 2011, In: Biological Psychology. 87, 2, p. 183 - 194 12 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Meta-Analysis 100%
  • Hypothalamic-Pituitary-Adrenal Axis 100%
  • Somatic Disorder 100%
  • Meta-Regression 100%
  • Association 42%
  180 Citations (Scopus)

• Oxcarbazepine for acute affective episodes in bipolar disorder

  Vasudev, A., Macritchie, K., Vasudev, K., Watson, S., Geddes, J. & Young, A., 2011, In: Cochrane Database of Systematic Reviews. N/A, 12, p. N/A 42 p., CD004857.

  Research output: Contribution to journal › Literature review › peer-review

  • Oxcarbazepine 100%
  • Mood Stabilizer 23%
  • Randomized Controlled Trial 15%
  • Tolerability 7%
  • Sodium Valproate 7%
  32 Citations (Scopus)

• Tiagabine in the maintenance treatment of bipolar disorder

  Vasudev, A., Macritchie, K., Rao, S. N. K., Geddes, J. & Young, A., 2011, In: Cochrane Database of Systematic Reviews. N/A, 12, p. N/A 19 p., 005173.

  Research output: Contribution to journal › Literature review › peer-review

  • Tiagabine 100%
  • Randomized Controlled Trial 27%
  • Mood Stabilizer 18%
  • Case Report 9%
  2 Citations (Scopus)
• 2010

  Toxoplasmosis as a cause for behaviour disorders - overview of evidence and mechanisms

  Fekadu, A., Shibre, T. & Cleare, A. J., 2010, In: Folia Parasitologica. 57, 2, p. 105 - 113 9 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Schizophrenia 100%
  • Human 66%
  • Animal 33%
  • Rodent 33%
  • Behavioral Effect 33%
  117 Citations (Scopus)
• 2009

  Magnetic resonance imaging studies in bipolar disorder and schizophrenia: meta-analysis

  Arnone, D., Cavanagh, J., Gerber, D., Lawrie, S. M., Ebmeier, K. P. & McIntosh, A. M., Sept 2009, In: British Journal of Psychiatry. 195, 3, p. 194-201 8 p., N/A.

  Research output: Contribution to journal › Literature review › peer-review

  • Magnetic Resonance Imaging 100%
  • Bipolar Disorder 100%
  • Brain 37%
  • Brain Areas 12%
  • Lateral Ventricle 12%
  353 Citations (Scopus)

• Randomised controlled trial to determine the clinical effectiveness and cost-effectiveness of selective serotonin reuptake inhibitors plus supportive care, versus supportive care alone, for mild to moderate depression with somatic symptoms in primary care: the THREAD (THREshold for AntiDepressant response) study

  Kendrick, T., Chatwin, J., Dowrick, C., Tylee, A., Morriss, R., Peveler, R., Leese, M., McCrone, P., Harris, T., Moore, M., Byng, R., Brown, G., Barthel, S., Mander, H., Ring, A., Kelly, V., Wallace, V., Gabbay, M., Craig, T. & Mann, A., Apr 2009, In: Health Technology Assessment. 13, 22, p. 1-159 159 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Randomized Controlled Trial 100%
  • Depression 100%
  • Primary Health Care 100%
  • Cost-Effectiveness Analysis 100%
  • Somatics 100%
  66 Citations (Scopus)

• The role of dopamine in bipolar disorder

  Cousins, D. A., Butts, K. & Young, A., Dec 2009, In: Bipolar Disorders. 11, 8, p. 787-806 20 p., N/A.

  Research output: Contribution to journal › Literature review › peer-review

  • Dopamine 100%
  • Bipolar Disorder 100%
  • Dopaminergic 37%
  • Dopaminergic System 25%
  • Dopamine Receptor 12%
  247 Citations (Scopus)

• What happens to patients with treatment-resistant depression? A systematic review of medium to long term outcome studies

  Fekadu, A., Wooderson, S., Markopoulo, K., Donaldson, C., Papadopoulos, A. & Cleare, A. J., Jul 2009, In: Journal of Affective Disorders. 116, 1-2, p. 4 - 11 8 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Long-Term Outcome 100%
  • Systematic Review 100%
  • Treatment-Resistant Depression 100%
  • Antidepressant 12%
  • Statistical Analysis 10%
  235 Citations (Scopus)

• Withdrawing Benzodiazepines in Primary Care

  Lader, M., Tylee, A. & Donoghue, J., 2009, In: CNS Drugs. 23, 1, p. 19 - 34 16 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Primary Health Care 100%
  • Patient 60%
  • Adverse Event 60%
  • Adverse Effect 60%
  • Therapeutic Procedure 40%
  208 Citations (Scopus)
• 2008

  Adjunctive aripiprazole imporves symptoms in antidepressant refractory major depressive disorder

  Cleare, A., 2008, In: Evidence-Based Mental Health. 11, 4, p. 111 1 p.

  Research output: Contribution to journal › Literature review › peer-review

  4 Citations (Scopus)

• Evidence-based guidelines for treating depressive disorders with antidepressants: A revision of the 2000 British Association for Psychopharmacology guidelines

  Anderson, I. M., Ferrier, I. N., Baldwin, R. C., Cowen, P. J., Howard, L., Lewis, G., Matthews, K., Allister-Williams, R. H., Peveler, R. C., Scott, J. & Tylee, A., Jun 2008, In: Journal of Psychopharmacology. 22, 4, p. 343-396 54 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Therapeutic Procedure 100%
  • Association 100%
  • Antidepressant 100%
  • Depression 100%
  • Drug Choice 33%
  437 Citations (Scopus)

• In vitro modulation of the glucocorticoid receptor by antidepressants

  Carvalho, L. A. & Pariante, C. M., 2008, In: Stress: The International Journal on the Biology of Stress. 11, 6, p. 411 - 424 14 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Antidepressant 100%
  • Glucocorticoid Receptor 100%
  • Glucocorticoid 25%
  • Patient 16%
  • Major Depressive Disorder 8%
  65 Citations (Scopus)

• Meta-analysis of magnetic resonance imaging studies of the corpus callosum in bipolar disorder

  Arnone, D., McIntosh, A. M., Chandra, P. & Ebmeier, K. P., Nov 2008, In: Acta Psychiatrica Scandinavica. 118, 5, p. 357-362 6 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Magnetic Resonance Imaging 100%
  • Meta-Analysis 100%
  • Corpus Callosum 100%
  • Bipolar Disorder 100%
  • Pathophysiology 40%
  87 Citations (Scopus)

• The HPA axis in major depression: classical theories and new developments

  Pariante, C. M. & Lightman, S. L., Sept 2008, In: Trends in Neurosciences. 31, 9, p. 464 - 468 5 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Major Depressive Disorder 100%
  • Psychiatry 50%
  1493 Citations (Scopus)

• The role of multi-drug resistance p-glycoprotein in glucocorticoid function: Studies in animals and relevance in humans

  Pariante, C. M., 7 Apr 2008, In: European Journal of Pharmacology. 583, 2-3, p. 263 - 271 9 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Animal 100%
  • Human 100%
  • Brain 40%
  • Therapeutic Effect 20%
  • Neuron 20%
  52 Citations (Scopus)
• 2007

  The armamentarium of treatments for bipolar disorder: a review of the literature

  Cousins, D. A. & Young, A. H., Jun 2007, In: International Journal of Neuropsychopharmacology . 10, 3, p. 411-431 21 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Atypical Antipsychotics 100%
  • Mood Stabilizer 100%
  • Atypical Antipsychotic 100%
  • Antipsychotic 33%
  • Tolerability 33%
  29 Citations (Scopus)
• 2004

  Do antidepressants regulate how cortisol affects the brain?

  Pariante, C. M., Thomas, S. A., Lovestone, S., Makoff, A. & Kerwin, R. W., May 2004, In: Psychoneuroendocrinology. 29, 4, p. 423 - 447 25 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Antidepressant 100%
  • Brain 100%
  • Cortisol 100%
  • Glucocorticoid 50%
  • Steroids 50%
  182 Citations (Scopus)

• Glucocorticoid receptor function in vitro in patients with major depression

  Pariante, C. M., Dec 2004, In: Stress: The International Journal on the Biology of Stress. 7, 4, p. 209 - 219 11 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Glucocorticoid Receptor 100%
  • Major Depressive Disorder 100%
  • Antidepressant 22%
  • Brain 22%
  • Glucocorticoid 11%
  132 Citations (Scopus)
• 2003

  Glucocorticoids and glucocorticoid receptors: mediators of fatigue?

  Cleare, A. J., Dec 2003, In: Acta Neuropsychiatrica. 15, 6, p. 341 - 353 13 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Mediator 100%
  • Fatigue 100%
  • Glucocorticoid 100%
  • Glucocorticoid Receptor 100%
  • Hydrocortisone 40%
  3 Citations (Scopus)

• Molecular mechanisms of glucocorticoid receptor sensitivity and relevance to affective disorders

  Juruena, M., Cleare, A. J., Bauer, M. E. & Pariante, C. M., Dec 2003, In: Acta Neuropsychiatrica. 15, 6, p. 354 - 367 14 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Glucocorticoid 100%
  • Brain 66%
  • Receptor Expression 66%
  • Cortisol 33%
  • Major Depressive Disorder 33%
  50 Citations (Scopus)

• The neuroendocrinology of chronic fatigue syndrome

  Cleare, A. J., 1 Apr 2003, In: Endocrine Reviews. 24, 2, p. 236 - 252 17 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Neuroendocrinology 100%
  • Patient 22%
  • Hydrocortisone 22%
  • Cortisol 22%
  • Drug Therapy 11%
  274 Citations (Scopus)
• 2002

  Fatigue, depression and chronic hepatitis C infection

  Wessely, S. & Pariante, C., 2002, In: Psychological Medicine. 32, 1, p. 1 - 10 10 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Infection 100%
  • Fatigue 100%
  • Chronic Hepatitis C 100%
  • Association 50%
  • Liver Disease 25%
  71 Citations (Scopus)

• Recovery from infectious mononucleosis: a case for more than symptomatic therapy? A systematic review

  Candy, B., Chalder, T., Cleare, A. J., Wessely, S., White, P. D. & Hotopf, M., 1 Oct 2002, In: British Journal of General Practice. 52, 483, p. 844 - 851 8 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Therapeutic Procedure 100%
  • Systematic Review 100%
  • Infectious Mononucleosis 100%
  • Health 44%
  • Disease 33%
  58 Citations (Scopus)
• 2001

  A systematic review of controlled trials of the effectiveness and cost-effectiveness of brief psychological treatments for depression

  Churchill, R., Hunot, V., Corney, R., Knapp, M., McGuire, P., Tylee, A. & Wessely, S., 2001, In: Health Technology Assessment. 5, 35, p. 1 - 173 173 p.

  Research output: Contribution to journal › Literature review › peer-review

  252 Citations (Scopus)

• Glial cell abnormalities in major psychiatric disorders: The evidence and implications

  Cotter, D. R., Pariante, C. M. & Everall, I. P., 15 Jul 2001, In: Brain Research Bulletin. 55, 5, p. 585 - 595 11 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Glial Cells 100%
  • Neuron 33%
  • Cerebral Cortex 16%
  • Glia 16%
  • Synapse 16%
  390 Citations (Scopus)

• Glucocorticoid receptors in major depression: Relevance to pathophysiology and treatment

  Pariante, C. M. & Miller, A. H., 1 Mar 2001, In: Biological psychiatry. 49, 5, p. 391 - 404 14 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Glucocorticoid Receptor 100%
  • Major Depressive Disorder 100%
  • Antidepressant 23%
  • Glucocorticoid 15%
  • Dexamethasone 15%
  1005 Citations (Scopus)

• The neuroendocrinology of chronic fatigue syndrome and fibromyalgia

  Parker, A. J. R., Wessely, S. & Cleare, A. J., 2001, In: Psychological Medicine. 31, 8, p. 1331 - 1345 15 p.

  Research output: Contribution to journal › Literature review › peer-review

  • Neuroendocrinology 100%
  • Cortisol 66%
  • Neurotransmitter 33%
  • Growth Hormone Treatment 16%
  173 Citations (Scopus)
• 2000

  Extracts from "clinical evidence" - Chronic fatigue syndrome

  Reid, S., Chalder, T., Cleare, A., Hotopf, M. & Wessely, S., 2000, In: BMJ, British Medical Journal (Clinical Research Ed.). 320, 7230, p. 292 - 296 5 p.

  Research output: Contribution to journal › Literature review › peer-review

  131 Citations (Scopus)