Chemistry

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• Towards understanding how post-translational modifications influence the decision making process of p53

  Davies, J. (Author), Muller, M. (Supervisor) & Brogan, A. (Supervisor), 1 Oct 2024

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Towards nanoparticle rational design: a multi-scale simulation investigation of the molecular mechanisms underpinning polymer based drug-delivery vehicles

  Lopez-Rios De Castro, R. (Author), Lorenz, C. (Supervisor) & Ulmschneider, M. B. (Supervisor), 1 Apr 2024

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Towards [FeFe]-H₂ase biomimics for H₂ oxidation

  Orton, G. (Author), Hogarth, G. (Supervisor), 1 Mar 2020

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Toward High Throughput Screening of Assembly-Optimised Ferritin Nanocage Libraries Applied to Nanotechnology

  Cornell, T. A. (Author), Orner, B. P. (Supervisor) & Sutton, B. J. (Supervisor), 2015

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The Synthesis and Characterisation of Novel Peptidomimetic Foldamers

  Stendall, R. (Author), Cobb, A. (Supervisor) & Muller, M. (Supervisor), 1 May 2023

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The roles of the co-chaperone SGTA/Sgt2, the BAG6 complex and E3 Ubiquitin Ligase RNF126 in cytosolic quality control

  Krysztofinska, E. M. (Author), McDonnell, J. M. (Supervisor) & Isaacson, R. L. (Supervisor), 2018

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Thermoelectrochemistry: potential application of gelled electrolytes, gold nanoparticles and novel redox systems

  Alzahrani, H. (Author), Aldous, L. (Supervisor), 1 Feb 2020

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The Rich Conformational Landscape of Musks and their Precursors Revealed by Broadband Rotational Spectroscopy

  Burevschi, E. (Author), Sanz, M. (Supervisor), 1 Aug 2021

  Student thesis: Doctoral Thesis › Doctor of Science

• The rich conformational landscape of musks and their precursors revealed by broadband rotational spectroscopy

  Burevschi, C. (Author), Sanz, M. (Supervisor), 1 Aug 2021

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• The droplet interface bilayer as a platform for a compartmentalized microreactor

  Allen-Benton, M. (Author), Booth, P. (Supervisor), 1 Jan 2021

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The Construction of α,δ-Foldamer into a 13/11 Helix and its Application in Organocatalysis

  Lin, Q. (Author), Cobb, A. (Supervisor) & Muller, M. (Supervisor), 1 Nov 2024

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Sugar Conjugates of 3-Hydroxy-4-pyridinones : Synthesis and Investigations into their Potential for Drug Delivery to the Brain.

  Fuchs, F. C. (Author), Hider, R. C. (Supervisor) & Wagner, G. K. (Supervisor), 2015

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• STUDY OF THE RELATIVE DOMAIN STABILITY OF A TWO-DOMAIN E.COLI MFS TRANSPORTER GLPT

  Kedzierski, M. K. (Author), Booth, P. (Supervisor) & Borysik, A. (Supervisor), 2018

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Structural and Functional Consequences of a Protein Backbone Modification

  Zhang, T. (Author), Muller, M. (Supervisor) & Isaacson, R. (Supervisor), 1 Sept 2022

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Single Molecule Interferometric Imaging of Molecular Assembly

  Guo, Y. (Author), Wallace, M. (Supervisor), 1 May 2024

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Single-Molecule Imaging of Botulinum Neurotoxin/A(0) Translocation

  Carniello, J. (Author), Wallace, M. (Supervisor) & Isaacson, R. (Supervisor), 1 Jun 2024

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Simulation-guided design of membrane active peptide-based therapeutics for biomedical applications

  Chen, C. (Author), Ulmschneider, M. (Supervisor), 1 Jul 2020

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Rotational studies of terpene clusters of atmospheric and biological relevance

  Murugachandran, S. I. (Author), Sanz, M. (Supervisor), 1 Mar 2023

  Student thesis: Doctoral Thesis › Doctor of Science

• ROLE OF KINETIC MECHANISMS IN DRUG DESIGN

  Badaoui, M. (Author), 1 Dec 2021

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Probing the dynamics of antibodies and membrane proteins by structural mass spectrometry

  Hansen, K. (Author), Politis, A. (Supervisor) & Sutton, B. (Supervisor), 1 Oct 2021

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• p53 as a molecular time bomb: a biochemical approach to dissect its regulation by posttranslational modifications

  Gerecht, K. (Author), Muller, M. (Supervisor) & Eggert, U. (Supervisor), 1 Mar 2021

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Organocatalytic access to γ-amino acids as building blocks for the synthesis of foldamers

  Fanelli, R. (Author), Cobb, A. (Supervisor), 1 Feb 2020

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Novel organocatalytic conjugate additions: towards the synthesis of biologically relevant targets

  Bryant, L. A. (Author), Cobb, A. (Supervisor) & Barry, S. M. (Supervisor), 1 Jul 2019

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Novel Dithiocarbamates for Applications in Materials Science

  Chandra Sarker, J. (Author), Hogarth, G. (Supervisor) & Ma, M. (Supervisor), 1 Jul 2022

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Molecular simulations of membrane binding and transport mechanisms with application to realistic vasculatures

  Troendle, E. (Author), Ulmschneider, M. (Supervisor), Isaacson, R. (Supervisor) & Rosta, E. (Supervisor), 1 Feb 2022

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Molecular and systems level models of the effects of protein aggregation on the cell cycle

  Jenkins, K. J. (Author), Csikasz-Nagy, A. (Supervisor) & Rosta, E. (Supervisor), 1 Jun 2019

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Mitochondria targeting metallopharmaceuticals for eradicating cancer stem cells

  Laws, K. (Author), Suntharalingam, R. (Supervisor), 1 May 2020

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Microsolvation and Aggregation of Polycyclic Aromatic Hydrocarbons: Structures and Interactions

  Saxena, S. (Author), Eykyn, T. R. (Supervisor) & Sanz Gonzalez, M. E. (Supervisor), 1 Dec 2022

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Microsolvation and Aggregation of Polycyclic Aromatic Hydrocarbons: Structures and Interactions

  Saxena, S. (Author), Sanz, M. (Supervisor), 1 Dec 2022

  Student thesis: Doctoral Thesis › Doctor of Science

• Irreversible Markov chain Monte Carlo samplers using the lifting framework and skewed detailed balance condition: algorithms and applications in computational statistical physics

  Faizi, F. (Author), Deligiannidis, G. (Supervisor) & Rosta, E. (Supervisor), 1 Aug 2021

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Investigation into the complex formation, biological action and biosynthesis of the natural products pyrrolomycins

  Planchat Calle, M. (Author), Barry, S. (Supervisor), 1 Jul 2020

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Investigating the molecular mechanism of the XylE sugar transporter

  Jia, R. (Author), Politis, A. (Supervisor), Booth, P. (Supervisor) & Reading, E. (Supervisor), 1 Feb 2023

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Investigating the elemental composition of peripheral sensory nerves and their function in paclitaxel-induced peripheral neuropathy

  Ferguson, C. (Author), Flatters, S. (Supervisor), McMahon, S. (Supervisor) & Fleck, R. (Supervisor), 1 Apr 2021

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Investigating and exploiting the late stage functionalisation of nonribosomal peptide antibiotics

  Perez Ortiz, G. (Author), Barry, S. (Supervisor) & Isaacson, R. (Supervisor), 1 Sept 2020

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Intein mediated engineering of cancer-selective toxic proteins

  Wyatt, J. (Author), Tavassoli, M. (Supervisor) & Muller, M. (Supervisor), 1 May 2022

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Insights into the structure, dynamics and interactions of large protein complexes using structural mass spectrometry

  Ahdash, Z. (Author), Politis, A. (Supervisor) & Conte, M. (Supervisor), 1 May 2020

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Explorations into Establishing a Rational Basis for Development of Emergent Function in Complex Chemical Systems

  Cross, E. (Author), Surman, A. (Supervisor), 1 Nov 2024

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Experimental and computational dissection of serine hydroxymethyltransferases within Mycobaterium tuberculosis

  Groom, D. (Author), academic, A. (Supervisor) & Ulmschneider, M. B. (Supervisor), 1 Apr 2023

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Examining the role of structural dynamics in the assembly and function of the multidrug efflux pump AcrAB-TolC

  Russell Lewis, B. (Author), Reading, E. (Supervisor) & Booth, P. J. (Supervisor), 1 Apr 2024

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Encapsulation of cancer stem cell potent metal complexes into polymeric nanoparticle for delivery

  Eskandari, A. (Author), Suntharalingam, R. (Supervisor), 1 May 2020

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Enantioselective, organocatalytic synthesis of carbocyclic structures pertaining to steroids

  Townsend, D. (Author), Cobb, A. (Supervisor), 1 Sept 2020

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Dynamics of macromolecular complexes through computational modelling and structural mass spectrometry

  Lau, A. M. C. (Author), Politis, A. (Supervisor), 1 Dec 2019

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Dissecting the PTM network of p53: a chemical approach to engineer the N-terminus of p53 using protein semi-synthesis

  Margiola, S. (Author), Muller, M. (Supervisor), 1 Mar 2022

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Development of Uncharged Galactosyltransferase Inhibitors: Chemical Tools for Applications in Cells

  Jiang, J. (Author), Wagner, G. K. (Supervisor) & Page, C. P. (Supervisor), 2017

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Development of hydrogen/deuterium exchange mass spectrometry simulations to enable accurate protein structure and complex selection

  Harris, M. (Author), Borysik, A. (Supervisor) & Isaacson, R. (Supervisor), 1 Jul 2021

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Development of carbohydrate-based inhibitors and probes for the interrogation of the bacterial proteome

  Metier, C. (Author), Barry, S. (Supervisor) & Wagner, G. (Supervisor), 1 Jan 2020

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Development of a Matrix Metalloproteinase-sensitive Förster Resonance Energy Transfer Sensor to monitor enzyme activity in 3D hydrogels in situ

  Yan, Z. (Author), Gentleman, E. (Supervisor), da Silva, R. (Supervisor) & Muller, M. (Supervisor), 1 Dec 2022

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Developing novel methods for co-translational studies of membrane protein folding

  Pellowe, G. (Author), Booth, P. (Supervisor), 1 Mar 2021

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Design and Analysis of Signal Processing Circuits for Molecular Communication

  Bi, D. (Author), Deng, Y. (Supervisor) & Salehi Reyhani, A. (Supervisor), 1 Aug 2022

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Conformational Flexibility and Chirality Recognition of Odorants elucidated by Broadband Rotational Spectroscopy

  Loru, D. (Author), Sanz, M. (Supervisor), 1 Feb 2018

  Student thesis: Doctoral Thesis › Doctor of Science