Research output per year
Research output per year
Organisation profile
Organisation profile
The major research interest of our lab is in how the differentiated state of
adult tissues is maintained. We study this using mammalian skin as a model
system. Current projects are concerned with self-renewal and lineage selection
by human and mouse epidermal stem cells, and the role of stem cells in tumour
formation. We are particularly interested in the interplay between intrinsic and
extrinsic factors in the regulation of cell fate decisions.
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Dive into the research topics where Gene Therapy and Regenerative Medicine is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.
Collaborations and top research areas from the last five years
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Profiles
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Robin Ali
- Gene Therapy and Regenerative Medicine - Director, KCL Centre for Cell and Gene Therapy, Professor of Human Molecular Genetics
Person: Academic
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Characterisation of Bruch’s membrane formation in human fetal retina and de novo membrane synthesis by hPSC-derived retinal pigment epithelium
Lanning, E., Branch, M., Harding, P., Margari, M., Smith, S., Ali, R. & Pearson, R., 21 May 2025, (Accepted/In press) In: Investigative Ophthalmology & Visual Science.Research output: Contribution to journal › Article › peer-review
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Human cone photoreceptor transplantation stimulates remodeling and restores function in AIPL1 model of end-stage Leber congenital amaurosis
Procyk, C. A., Melati, A., Ribeiro, J., Liu, J., Branch, M. J., Delicata, J. D., Tariq, M., Kalarygrou, A. A., Kapadia, J., Khorsani, M. M., West, E. L., Smith, A. J., Gonzalez-Cordero, A., Ali, R. R. & Pearson, R. A., 8 Apr 2025, (E-pub ahead of print) In: Stem cell reports. 20, 4, 102470.Research output: Contribution to journal › Article › peer-review
Open Access -
Human cone photoreceptor transplantation stimulates retinal remodelling and restores retinal and visual function in AIPL1 mouse model of end-stage Leber Congenital Amaurosis
Procyk, C., Melati, A., Ribeiro, J., Liu, J., Branch, M., Tariq, M., Kalargyrou, A., Moshtagh Khorasani, M., West, E., Smith, S., Gonzalez-Cordero, A., Ali, R. & Pearson, R., 19 Feb 2025, (Accepted/In press) In: Stem Cell Reports.Research output: Contribution to journal › Article › peer-review
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Investigating immune cell interactions in early fibrotic lung disease using spatial transcriptomics
Hewitt, R. (Primary Investigator) & Vigilante, A. (Co-Investigator)
1/12/2024 → 30/11/2026
Project: Research
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The role of SETD1B in somatic hypermutation and germinal center physiology
Pavri, R. (Primary Investigator) & Vigilante, A. (Co-Investigator)
BBSRC Biotechnology and Biological Sciences Research Council
4/11/2024 → 3/11/2027
Project: Research
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Translating science into the clinic - new approaches and tools for predicting risk of preterm birth
Tribe, R. (Primary Investigator), Martinez Nunez, R. (Co-Investigator) & Vigilante, A. (Co-Investigator)
1/10/2024 → 30/09/2027
Project: Research
Activities
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Eczema sufferers have lower skin cancer risk
Watt, F. (Interviewee)
6 May 2014Activity: Other › Types of Public engagement and outreach - Media article or participation
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Royal Society public lecture - Stem cells and human health
Watt, F. (Speaker)
2014Activity: Other › Types of Public engagement and outreach - Public lecture/debate/seminar
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BBC Radio 4 - "Inside Science"
Watt, F. (Interviewee)
12 Sept 2013Activity: Other › Types of Public engagement and outreach - Media article or participation
Student theses
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Analysis of Stem Cell Interactions At Single Cell Resolution
Reimer, A. S. (Author), Watt, F. M. (Supervisor) & Bates, G. (Supervisor), 2015Student thesis: Doctoral Thesis › Doctor of Philosophy
File -
Beta-blockers: functional properties and signalling mechanisms in cancer cell lines
Reyes Corral, M. (Author), Ahmed, A. (Supervisor) & Dasgupta, P. (Supervisor), 1 Oct 2020Student thesis: Doctoral Thesis › Doctor of Philosophy
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Characterisation of human induced pluripotent stem cells in 3D artificial microenvironment using high content analysis
Alsehli, H. (Author), Gentleman, E. D. (Supervisor) & Danovi, D. (Supervisor), 1 Sept 2023Student thesis: Doctoral Thesis › Doctor of Philosophy
File
Prizes
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Future Leader Innovation Enterprise and Research
Danovi, D. (Recipient), Jan 2020
Prize: Other distinction
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"Most Outstanding Contribution to Public Engagement"
Watt, F. (Recipient), 20 Nov 2013
Prize: Prize (including medals and awards)
Datasets
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R scripts for the processing, analysis, and visualisation of single cell RNA sequencing data relating to the thesis titled: Combining localised bioengineering with systemic approaches to rejuvenate skeletal stem/progenitor cells for bone repair, by Joshua Reeves
Reeves, J., King's College London, 20 Sept 2024
DOI: 10.18742/27020395, https://kcl.figshare.com/articles/software/R_scripts_for_the_processing_analysis_and_visualisation_of_single_cell_RNA_sequencing_data_relating_to_the_thesis_titled_Combining_localised_bioengineering_with_systemic_approaches_to_rejuvenate_skeletal_stem_progenitor_cells_for_bone_repai/27020395
Dataset