Medical & Molecular Genetics

Projects

Projects per year 1992 2008 2009 2010 2011 2013 2014 2015 2018 2032

• 3 Not started
• 29 Active
• 454 Finished

Projects per year

Search results

• Finished

  Epigenetics of B lymphocytes in systemic lupus erythematosus

  Vyse, T. (Primary Investigator), Bell, J. (Co-Investigator), Cope, A. (Co-Investigator) & Cunninghame Graham, D. (Co-Investigator)

  1/09/2014 → 31/08/2015

  Project: Research

• How does the genome achieve transcriptome diversity? (PROVISIONAL TITLE)

  Oakey, R. (Primary Investigator) & Schulz, R. (Co-Investigator)

  1/09/2014 → 31/08/2017

  Project: Research

• Integrating systems biology data into complex disease genetics studies

  Morris, D. (Primary Investigator)

  1/09/2014 → 31/08/2017

  Project: Research

• Molecular genetic analysis of frontal fibrosing alopecia

  McGrath, J. (Primary Investigator), Simpson, M. (Co-Investigator) & Watt, F. (Co-Investigator)

  6/08/2014 → 5/08/2017

  Project: Research

• Molecular Genetic Analysis of Frontal Fibrosing Alopecia

  Barker, J. (Primary Investigator), Simpson, M. (Co-Investigator) & Watt, F. (Co-Investigator)

  6/08/2014 → 5/08/2017

  Project: Research

• Regulation of Keratinocyte innate immune genes by psoriasis susceptibility alleles

  Barker, J. (Primary Investigator), Capon, F. (Co-Investigator), Mahil, S. (Co-Investigator) & Trembath, R. (Co-Investigator)

  MRC Medical Research Council

  1/07/2014 → 30/06/2017

  Project: Research

• To develop and apply statistical models for systems biology in complex disease.

  Morris, D. (Primary Investigator)

  1/07/2014 → 30/06/2015

  Project: Research

• Targeting the innate immune system in Huntington's disease

  Bates, G. (Primary Investigator)

  MRC Medical Research Council

  1/07/2014 → 31/08/2018

  Project: Research

• Analysis of Systems Biology data in complex disease genetics

  Morris, D. (Primary Investigator)

  1/06/2014 → 30/05/2017

  Project: Research

• A systems biology approach to studying skeletal muscle ageing

  Timmons, J. (Primary Investigator)

  MRC Medical Research Council

  1/05/2014 → 30/06/2016

  Project: Research

• USING COMPUTATION, METABOLOMICS AND NEXT GENERATION SEQUENCING TO STUDY THE METABOLISM OF THE FAILING HEART

  Edwards, L. (Primary Investigator), Clark, J. (Co-Investigator), Shattock, M. (Co-Investigator) & Weale, M. (Co-Investigator)

  1/05/2014 → 30/04/2017

  Project: Research

• Ancestry and biological Informative Markers for stratification of Hypertension: the AIM HY study

  Chowienczyk, P. (Primary Investigator), Brown, M. (Co-Investigator), Chaturvedi, N. (Co-Investigator), Cruickshank, K. (Co-Investigator), Delaney, B. (Co-Investigator), Heagerty, A. (Co-Investigator), Hughes, A. (Co-Investigator), Lewis, C. (Co-Investigator), Mander, A. (Co-Investigator), Mant, J. (Co-Investigator), Martini, G. (Co-Investigator), McKevitt, C. (Co-Investigator), Parkin, D. (Co-Investigator), Prevost, T. (Co-Investigator), Spector, T. (Co-Investigator), Valdes, A. (Co-Investigator), Weale, M. (Co-Investigator), Wilkinson, I. (Co-Investigator) & Wolfe, C. (Co-Investigator)

  MRC Medical Research Council

  14/04/2014 → 31/12/2023

  Project: Research

• Psoriasis Stratification to Optimise Relevant Therapy (PSORT)

  Barker, J. (Primary Investigator), Capon, F. (Co-Investigator), Nestle, F. (Co-Investigator), Simpson, M. (Co-Investigator), Smith, C. (Co-Investigator) & Di Meglio, P. (Co-Investigator)

  MRC Medical Research Council

  7/04/2014 → 31/05/2021

  Project: Research

  • Psoriasis 100%
  • Therapeutic Procedure 100%

• The Brazilian Bipolar Family Study : A 5 year follow-up study and molecular characterisation of phenotypes and mutations

  Breen, G. (Primary Investigator), McGuffin, P. (Co-Investigator) & Weale, M. (Co-Investigator)

  1/04/2014 → 31/03/2017

  Project: Research

• Linking DNA methylation to disease severity in sickle cell anaemia

  Oakey, R. (Primary Investigator) & Thein, S. L. (Co-Investigator)

  1/04/2014 → 31/03/2015

  Project: Research

• The shared genetic landscape of autoinflammatory disorders: a window into the molecular mechanisms regulating IL-1 production

  Capon, F. (Primary Investigator)

  1/03/2014 → 28/02/2018

  Project: Research

• Functional Genomics of SLE

  Vyse, T. (Primary Investigator)

  1/03/2014 → 28/02/2019

  Project: Research

• Functional Genomics in SLE: A Transancestral Approach

  Vyse, T. (Primary Investigator), Cunninghame Graham, D. (Co-Investigator) & Morris, D. (Co-Investigator)

  MRC Medical Research Council

  13/01/2014 → 12/04/2015

  Project: Research

• Genetics, School Environments and Cognitive Development

  Plomin, R. (Primary Investigator) & Simpson, M. (Co-Investigator)

  12/01/2014 → 30/11/2019

  Project: Research

• Statistical Analyss of complex disease sub-phenotype data in genetic association studies

  Morris, D. (Primary Investigator)

  6/01/2014 → 5/01/2017

  Project: Research

• IL-1 signalling antagonists in the treatment of severe pustular psoriasis

  Capon, F. (Primary Investigator), Barker, J. (Co-Investigator) & academic, A. (Co-Investigator)

  3/01/2014 → 2/01/2015

  Project: Research

• Molecular mechanisms of cardiovasculogenesis: genetic and functional analysis in congenital limb, scalp and cardiac defects

  Southgate, L. (Primary Investigator)

  1/01/2014 → 31/12/2017

  Project: Research

• Targeted DNA sequencing in Indian and European samples contributes to casual allele identification for lupus

  Vyse, T. (Primary Investigator) & Cunninghame Graham, D. (Co-Investigator)

  Arthritis Research UK

  1/01/2014 → 11/01/2017

  Project: Research

• A high throughput next generation sequencing strategy for accurate typing of classical and non-classical HLA genes

  Fernando, M. M. (Primary Investigator) & Simpson, M. (Co-Investigator)

  1/01/2014 → 31/12/2016

  Project: Research

• Epigenetic control of RNA processing

  Oakey, R. (Primary Investigator) & Schulz, R. (Primary Investigator)

  1/01/2014 → 31/12/2016

  Project: Research

• The prevention and treatment of the complications of transplantation by stratification of risk

  Lord, G. (Primary Investigator), Hernandez Fuentes, M. (Co-Investigator) & Weale, M. (Co-Investigator)

  1/01/2014 → 31/12/2017

  Project: Research

• Understanding the genetics of healthy skeletal muscle, the gatekeeper at the nexus between human health and disease

  Edwards, L. (Primary Investigator), Harridge, S. (Primary Investigator) & Weale, M. (Co-Investigator)

  1/01/2014 → 31/12/2016

  Project: Research

• The Genetic Basis of Keloids

  McGrath, J. (Primary Investigator) & Simpson, M. (Co-Investigator)

  Rosetrees Trust

  1/12/2013 → 30/11/2015

  Project: Research

• The role of ubiquitination in Systemic Lupus Erythematosus [F2]

  academic, A. (Primary Investigator) & Vyse, T. (Co-Investigator)

  Isaac Schapera Research Trust

  1/12/2013 → 3/04/2014

  Project: Research

• Defining molecular mechanisms underlying the pathogenesis of APL and therapy-related leukaemias

  Grimwade, D. (Primary Investigator) & Solomon, E. (Primary Investigator)

  Blood Cancer UK

  1/12/2013 → 30/11/2018

  Project: Research

• Profiling metabolic complications associated with anti-retroviral treatment

  Huthoff, H. (Primary Investigator), Cason, J. (Co-Investigator), Edwards, L. (Co-Investigator), Post, F. (Co-Investigator) & Schulz, R. (Co-Investigator)

  KHP King's Health Partners

  1/11/2013 → 30/06/2015

  Project: Research

• Uncovering mechanisms underlying the transdifferentiation of human muscle fibroblasts into adipocytes

  Harridge, S. (Primary Investigator), Edwards, L. (Co-Investigator), Ellison, G. (Co-Investigator), Weale, M. (Co-Investigator), Agley, C. (Co-Investigator) & academic, A. (Co-Investigator)

  BBSRC Biotechnology and Biological Sciences Research Council, GSK GlaxoSmithKline Research & Development Ltd

  1/11/2013 → 31/08/2017

  Project: Research

• SLE pathogenesis: the molecular basis for multiple association signals in IKZF2

  Cunninghame Graham, D. (Primary Investigator)

  Arthritis Research UK

  1/10/2013 → 30/09/2016

  Project: Research

• Examination of genome-wide, long-range interactions of promoters in MLL leukaemias

  Grimwade, D. (Primary Investigator) & Osborne, C. (Primary Investigator)

  Blood Cancer UK

  1/10/2013 → 31/03/2017

  Project: Research

• Examination of genome-wide, long-range interactions of promoters in AML

  Osborne, C. (Primary Investigator) & Grimwade, D. (Co-Investigator)

  1/10/2013 → 30/09/2016

  Project: Research

• A study of the predictors of extreme response to TNF4 therapy in patients with rheumatoid arthritis

  Cope, A. (Primary Investigator), Al-sarraj, S. (Co-Investigator), Galloway, J. (Co-Investigator) & Simpson, M. (Co-Investigator)

  1/10/2013 → 30/09/2016

  Project: Research

• Wood as an archive of epigenetic modifications of the genome over time

  Schulz, R. (Primary Investigator)

  1/10/2013 → 30/09/2014

  Project: Research

• Regulation of keratinocyte innate immune genes by psoriasis susceptibility alleles

  Barker, J. (Primary Investigator), Capon, F. (Co-Investigator), Mahil, S. (Co-Investigator) & Trembath, R. (Co-Investigator)

  1/10/2013 → 30/09/2016

  Project: Research

• Prospecting epigenetic markers for growth and neurological disorders in assisted reproduction

  Oakey, R. (Primary Investigator) & Josifova, D. (Co-Investigator)

  1/10/2013 → 30/09/2014

  Project: Research

• A feasibility study to explore the influence of genetic background on nephrotic syndrome and treatment response using whole exome sequencing and genotype phenotype correlation

  Koziell, A. (Primary Investigator), Lord, G. (Co-Investigator) & Simpson, M. (Co-Investigator)

  1/09/2013 → 31/08/2014

  Project: Research

• The genetic basis of keloids

  McGrath, J. (Primary Investigator) & Simpson, M. (Co-Investigator)

  1/09/2013 → 31/08/2015

  Project: Research

• Evidence for Pharmaceutical Harm: Philosophical Investigations

  Weale, M. (Primary Investigator)

  1/09/2013 → 31/08/2015

  Project: Research

• IL-1 signalling antagonists in the treatment of severe pustular psoriasis

  Capon, F. (Primary Investigator), Barker, J. (Co-Investigator) & academic, A. (Co-Investigator)

  1/09/2013 → 31/08/2014

  Project: Research

• Deep sequencing of tumour and plasma DNA for monitoring squamous cell cancer

  Mathew, C. (Primary Investigator), Gossage, J. (Co-Investigator), Lagergren, J. (Co-Investigator), McGurk, M. (Co-Investigator), Odell, E. (Co-Investigator) & Simpson, M. (Co-Investigator)

  KHP King's Health Partners

  1/07/2013 → 31/12/2014

  Project: Research

• MC IEF Barbara Furnrohr

  Vyse, T. (Primary Investigator)

  1/06/2013 → 31/05/2015

  Project: Research

• Delineating the endocardial epigenome

  Oakey, R. (Primary Investigator)

  BHF British Heart Foundation

  1/06/2013 → 31/10/2015

  Project: Research

• Complement receptor 3 variation and the immunogenetics of the human cellular innate immune system in systemic lupus erythematosus

  Rhodes, B. (Primary Investigator) & Vyse, T. (Co-Investigator)

  1/04/2013 → 31/03/2017

  Project: Research

• Determining the molecular basis of currently uncharacterised forms of Epidermolysis Bullosa (EB)

  McGrath, J. (Primary Investigator) & Simpson, M. (Co-Investigator)

  1/04/2013 → 31/03/2014

  Project: Research

• Cyclin dependent kinase interacting protein in controlling neuronal plasticity

  Yu, V. (Primary Investigator)

  21/03/2013 → 20/03/2017

  Project: Research

• Creation of the UK-India SLE ImmunoGenetics Network

  Vyse, T. (Primary Investigator) & Cunninghame Graham, D. (Co-Investigator)

  7/03/2013 → 31/03/2016

  Project: Research