Medical & Molecular Genetics

Projects

Projects per year 1992 2008 2009 2010 2011 2013 2014 2015 2032

• 4 Not started
• 30 Active
• 452 Finished

Projects per year

Search results

• Finished

  Development of an in utero approach for thassaemia gene therapy

  Antoniou, M. (Primary Investigator) & Waddington, S. (Co-Investigator)

  UK Thalassaemia Society

  1/01/2008 → 30/04/2011

  Project: Research

• Tissue-specific gene regulation via alternative poly-adulation due to internal promoter activity

  Schulz, R. (Primary Investigator)

  1/01/2008 → 31/12/2012

  Project: Research

• A genome-wide approach to the characterisation of human and murine DNA methylation mutants.

  Oakey, R. (Primary Investigator) & academic, A. (Co-Investigator)

  Wellcome Trust

  1/01/2008 → 31/05/2011

  Project: Research

• Genetics Analysis of Psoriasis: the GAP study

  Trembath, R. (Primary Investigator) & Barker, J. (Co-Investigator)

  Wellcome Trust

  1/12/2007 → 30/12/2011

  Project: Research

• Genome-wide association scan in ulcerative colitis: characterising genetic determinants of susceptibility and disease phenotype

  Mathew, C. (Primary Investigator)

  Wellcome Trust

  1/12/2007 → 15/12/2010

  Project: Research

• HLA-C as candidate gene in psoriasis

  Nestle, F. (Primary Investigator), Mak, R. (Co-Investigator), Trembath, R. (Co-Investigator) & Yanez, R. (Co-Investigator)

  MRC Medical Research Council

  1/11/2007 → 13/01/2011

  Project: Research

• A molecular genetic investigation of acne vulgaris: identification of susceptibility genes relevant to disease pathogenesis.

  Smith, C. (Primary Investigator), Barker, J. (Co-Investigator), Bataille, V. (Co-Investigator), Burden, D. (Co-Investigator), Leyton, A. (Co-Investigator), Spector, T. (Co-Investigator), Trembath, R. (Co-Investigator) & Zahradnik, D. R. (Co-Investigator)

  British Skin Foundation

  1/11/2007 → 31/03/2010

  Project: Research

• The impact of PLZF on human male factor infertility

  Guidez, F. (Primary Investigator)

  Infertility Research Trust

  1/10/2007 → 30/11/2010

  Project: Research

• Interactions of the dystrophin protein

  Roberts, R. (Primary Investigator)

  Muscular Dystrophy UK

  1/10/2007 → 30/09/2010

  Project: Research

• Role of de-ubiquitinating enzymes and ubiquition binding proteins in breast tumourigenesis.

  Morris, J. (Primary Investigator) & Solomon, E. (Primary Investigator)

  Breast Cancer Campaign

  1/10/2007 → 30/09/2010

  Project: Research

• The role of genes predisposing to epithelial inflammation in the pathogenesis of psoriasis

  Capon, F. (Primary Investigator), Barker, J. (Co-Investigator) & Trembath, R. (Co-Investigator)

  Psoriasis Association

  1/10/2007 → 31/01/2011

  Project: Research

• Breakthrough Breast Cancer Unit - 'Sarah Greene Clinical Research Fellowship'

  Parker, P. (Primary Investigator), Purushotham, A. (Primary Investigator), Tutt, A. (Primary Investigator), Gillett, C. (Co-Investigator), Morris, J. (Co-Investigator), Ng, T. (Co-Investigator), Pinder, S. (Co-Investigator), Ramirez, A.-J. (Co-Investigator) & academic, A. (Co-Investigator)

  Breakthrough Breast Cancer

  1/10/2007 → 31/08/2014

  Project: Research

• Genome-wide autozygosity mapping in a consanguineous family with a novel myotonic disorder.

  Green, P. (Primary Investigator), Roberts, R. (Primary Investigator), Gill, H. (Co-Investigator) & Longman, D. (Co-Investigator)

  Newlife Foundation

  1/09/2007 → 30/11/2009

  Project: Research

• Functional characterisation of the major susceptibility locus (PSORS1) for cutaneous inflammation in psoriasis

  Trembath, R. (Primary Investigator), Barker, J. (Co-Investigator), Hayday, A. (Co-Investigator) & Nestle, F. (Co-Investigator)

  MRC Medical Research Council

  23/07/2007 → 22/07/2012

  Project: Research

• British-German academic research collaboration programme (ARC)

  Schlitt, T. (Primary Investigator)

  British Council - Germany

  1/07/2007 → 30/06/2011

  Project: Research

• New diagnostic and treatment approaches in organ and stem cell transplantation (MRC Centre for Transplantation)

  Sacks, S. (Primary Investigator), De Bari, C. (Co-Investigator), Hayday, A. (Co-Investigator), Lechler, R. (Co-Investigator), Nestle, F. (Co-Investigator), Razavi, R. (Co-Investigator), Sharpe, P. (Co-Investigator) & Solomon, E. (Co-Investigator)

  MRC Medical Research Council

  1/04/2007 → 31/12/2012

  Project: Research

• NIHR Biomedical Research Centre

  Afzali, B. (Primary Investigator), Antoniou, M. (Primary Investigator), Barker, J. (Primary Investigator), Barratt, B. (Primary Investigator), Beighton, D. (Primary Investigator), Bevan, S. (Primary Investigator), Blower, P. (Primary Investigator), Burchell, J. (Primary Investigator), Cason, J. (Primary Investigator), Chappell, L. (Primary Investigator), Cope, A. (Primary Investigator), Corrigan, C. (Primary Investigator), Cunninghame Graham, D. (Primary Investigator), Dontu, G. (Primary Investigator), Edgeworth, J. (Primary Investigator), Farzaneh, F. (Primary Investigator), Gee, T. (Primary Investigator), Gould, H. (Primary Investigator), Green, P. (Primary Investigator), Greenough, A. (Primary Investigator), Grigoriadis, A. (Primary Investigator), Hayday, A. (Primary Investigator), Higginson, I. (Primary Investigator), Kalra, L. (Primary Investigator), Karagiannis, S. (Primary Investigator), Kelly, F. (Primary Investigator), Kemper, C. (Primary Investigator), Lau-Walker, M. (Primary Investigator), Lavender, P. (Primary Investigator), Lee, T. (Primary Investigator), Lempp, H. (Primary Investigator), Lewis, C. (Primary Investigator), Lombardi, G. (Primary Investigator), Lord, G. (Primary Investigator), Marber, M. (Primary Investigator), Mason, J. (Primary Investigator), Mathew, C. (Primary Investigator), McGrath, J. (Primary Investigator), Metcalfe, A. (Primary Investigator), Molokhia, M. (Primary Investigator), Mullen, G. (Primary Investigator), Nagel, E. (Primary Investigator), Neil, S. (Primary Investigator), Nestle, F. (Primary Investigator), Oakey, R. (Primary Investigator), Parker, P. (Primary Investigator), Peakman, M. (Primary Investigator), Perera, D. (Primary Investigator), Purushotham, A. (Primary Investigator), Rasekh Ahmadi, K. (Primary Investigator), Rashid, T. (Primary Investigator), Razavi, R. (Primary Investigator), Ridley, A. (Primary Investigator), Robson, M. (Primary Investigator), Sacks, S. (Primary Investigator), Sanchez Fueyo, A. (Primary Investigator), Santis, G. (Primary Investigator), Sanz Moreno, V. (Primary Investigator), Sawyer, E. (Primary Investigator), Schaeffter, T. (Primary Investigator), Shah, A. (Primary Investigator), Sharpe, P. (Primary Investigator), Simpson, M. (Primary Investigator), Smith, R. (Primary Investigator), Sorinola, I. (Primary Investigator), Spector, T. (Primary Investigator), Spicer, J. (Primary Investigator), Taams, L. (Primary Investigator), Tavassoli, M. (Primary Investigator), Taylor, D. (Primary Investigator), Tree, T. (Primary Investigator), Trembath, R. (Primary Investigator), Tribe, R. (Primary Investigator), Tutt, A. (Primary Investigator), Waltham, M. (Primary Investigator), Watt, F. (Primary Investigator), Webb, A. (Primary Investigator), Wells, C. (Primary Investigator), Whelan, K. (Primary Investigator), Whitaker, J. (Primary Investigator), Whittlesea, C. (Primary Investigator), Williamson, C. (Primary Investigator), Wolfe, C. (Primary Investigator), Yu, V. (Primary Investigator), academic, A. (Primary Investigator), Hughes, S. (Co-Investigator), Montana, G. (Co-Investigator), Rhode, K. (Co-Investigator), Schnabel, J. (Co-Investigator) & Tziotzios, C. (Co-Investigator)

  NIHR National Institute For Health & Care Research, DHSC Department of Health and Social Care

  1/04/2007 → 31/03/2017

  Project: Research

  • T-Helper Cell 100%
  • Inflammatory Arthritis 66%
  • Interleukin 17 66%
  • T Cell 44%
  • Interleukin 10 41%

• The development of new c-myc-ERTAM conditional immortalising technologies of primary human somatic stem cells employing homologous recombination and lentiviral vectors

  Antoniou, M. (Primary Investigator)

  AEA Technology plc, ReNeuron Ltd

  1/04/2007 → 31/01/2010

  Project: Research

• Investigation of genetic susceptibility to inflammatory bowel disease

  Mathew, C. (Primary Investigator) & Lewis, C. (Co-Investigator)

  Wellcome Trust

  1/03/2007 → 29/02/2012

  Project: Research

• Validation of diagnostic tests for BRCA1-mediated cancer predisposition

  Morris, J. (Primary Investigator), Solomon, E. (Primary Investigator) & Gillett, C. (Co-Investigator)

  Guy's & St Thomas' Charity

  1/03/2007 → 28/02/2010

  Project: Research

• Identification of desmoglein 3(DSG3) mutations in patients with pemphigus vulgaris

  Capon, F. (Primary Investigator)

  British Skin Foundation

  1/01/2007 → 31/12/2007

  Project: Research

• Role of NBR1 in bone remodelling

  Solomon, E. (Primary Investigator) & Whitehouse, C. (Primary Investigator)

  Arthritis Research UK

  1/01/2007 → 31/07/2012

  Project: Research

• Autozygosity mapping and identification of recessive disease genes in consanguineous families

  Trembath, R. (Primary Investigator)

  Wellcome Trust

  1/11/2006 → 31/10/2009

  Project: Research

• RCUK Fellowship

  Lumsden, A. (Primary Investigator), Malim, M. (Primary Investigator), Roueche, C. (Primary Investigator), Shah, A. (Primary Investigator), Solomon, E. (Primary Investigator), Trapp, M. (Primary Investigator) & academic, A. (Primary Investigator)

  EPSRC Engineering and Physical Sciences Research Council, Research Councils UK

  1/10/2006 → 30/09/2012

  Project: Research

• Molecular Genetics Mechanisms in Idiopathic Pulmonary Arterial Hypertension.

  Trembath, R. (Primary Investigator)

  BHF British Heart Foundation

  1/10/2006 → 30/09/2009

  Project: Research

• King's Experimental Cancer Centre

  Parker, P. (Primary Investigator), Purushotham, A. (Primary Investigator), Blower, P. (Co-Investigator), Burchell, J. (Co-Investigator), Diebold, S. (Co-Investigator), Ellis, P. (Co-Investigator), Farzaneh, F. (Co-Investigator), Gillett, C. (Co-Investigator), Grimwade, D. (Co-Investigator), Harries, M. (Co-Investigator), Hayday, A. (Co-Investigator), Lewis, C. (Co-Investigator), Marsden, P. (Co-Investigator), Mufti, G. (Co-Investigator), Møller, H. (Co-Investigator), Nestle, F. (Co-Investigator), Ng, T. (Co-Investigator), O'Doherty, M. (Co-Investigator), Sawyer, E. (Co-Investigator), Schey, S. (Co-Investigator), Solomon, E. (Co-Investigator), Spencer, J. (Co-Investigator), Taylor-Papadimitriou, J. (Co-Investigator), Tutt, A. (Co-Investigator) & Whittaker, S. (Co-Investigator)

  CRUK Cancer Research UK

  1/08/2006 → 31/03/2012

  Project: Research

• Twins UK Genetic Epidemiology Resource

  Spector, T. (Primary Investigator), Carter, N. (Co-Investigator), Hammond, C. (Co-Investigator), Sham, P. (Co-Investigator) & Solomon, E. (Co-Investigator)

  Wellcome Trust

  1/08/2006 → 30/09/2011

  Project: Research

• Defining the role of PML and the nuclear bodies in haematopoiesis and the pathogenesis of acute promyelocytic leukaemia

  Grimwade, D. (Primary Investigator) & Solomon, E. (Co-Investigator)

  Blood Cancer UK

  1/08/2006 → 31/03/2012

  Project: Research

• Molecular mechanisms of BMPR-II dysfunction underlying primary pulmonary hypertension.

  Trembath, R. (Primary Investigator)

  BHF British Heart Foundation

  1/07/2006 → 30/06/2008

  Project: Research

• BRCA gene variants in breast cancer

  Morris, J. (Primary Investigator) & Solomon, E. (Primary Investigator)

  Breast Cancer Campaign

  1/06/2006 → 31/12/2011

  Project: Research

• Platelet-derived growth factor inhibition in idiopathic and familial pulmonary arterial hypertension

  Trembath, R. (Primary Investigator)

  MRC Medical Research Council

  1/05/2006 → 30/04/2009

  Project: Research

• National Autozygosity Mapping Resource (NAMR)

  Trembath, R. (Primary Investigator)

  Wellcome Trust

  1/03/2006 → 30/04/2007

  Project: Research

• The Molecular genetics of Pulmonary Arterial Hypertension.

  Trembath, R. (Primary Investigator)

  BHF British Heart Foundation

  1/02/2006 → 30/06/2008

  Project: Research

• Non-invasive methods for DNA sample collection in inflammatory bowel disease patients.

  Prescott, N. (Primary Investigator) & Ragoussis, I. (Primary Investigator)

  Friends of Guy's Hospital

  1/01/2006 → 31/12/2006

  Project: Research

• PULMONARY HYPERTENSION: Functional Genomics and Therapy of Lung Vascular Remodelling - 'PULMOTENSION'

  Trembath, R. (Primary Investigator)

  EC European Commission

  1/01/2006 → 31/12/2009

  Project: Research

• Insights to novel therapeutic strategies for a nuclear inclusion disease caused by polyalanine expansion - PolyALA

  Antoniou, M. (Primary Investigator)

  EC European Commission

  1/01/2006 → 30/06/2009

  Project: Research

• Gene duplication and mutation detection in Haemophilia A.

  Green, P. (Primary Investigator)

  Friends of Guy's & St.Thomas' Hospital

  1/12/2005 → 30/11/2006

  Project: Research

• Identifying genes for bipolar associated disorder

  Oakey, R. (Primary Investigator)

  Friends of Guy's Hospital

  1/11/2005 → 31/10/2006

  Project: Research

• Bioinformatics analysis of microarray data and epigenetics

  Oakey, R. (Primary Investigator) & Schulz, R. (Primary Investigator)

  EMBO European Molecular Biology Organisation

  1/10/2005 → 30/09/2007

  Project: Research

• Genetic Role Investigation Of The NF-kB Pathway in Susceptibility To Inflammatory Bowel Disease

  Mathew, C. (Primary Investigator)

  Crohn's and Colitis UK

  1/05/2005 → 30/04/2007

  Project: Research

• Modelling Complex Genetic Disease

  Lewis, C. (Primary Investigator), Whittaker, S. (Primary Investigator), Mathew, C. (Co-Investigator) & Steer, S. (Co-Investigator)

  Wellcome Trust

  1/04/2005 → 31/03/2008

  Project: Research

• Evaluation Of Real time Quantitative Approach In Acute Promyelocytic Leukaemia

  Grimwade, D. (Primary Investigator)

  Blood Cancer UK

  1/02/2005 → 30/06/2010

  Project: Research

• Development of plasmid and lentiviral muscle gene therapy vectors incorporating the human desmin locus control region.

  Antoniou, M. (Primary Investigator)

  AFM Association Française contre les Myopathies

  1/10/2004 → 30/09/2005

  Project: Research

• Determination underlying the formation of reciprocal chromosomal translocations in leukaemia

  Grimwade, D. (Primary Investigator) & Solomon, E. (Primary Investigator)

  Blood Cancer UK

  1/10/2004 → 30/09/2009

  Project: Research

• Salary for Janet Ball

  Solomon, E. (Primary Investigator)

  St George's, University of London

  1/06/2004 → 31/05/2005

  Project: Research

• Mouse to Arabidopsis Transkingdom approaches to discovery of imprinted genes and analysis of genomic context

  Oakey, R. (Primary Investigator)

  BBSRC Biotechnology and Biological Sciences Research Council

  1/04/2004 → 31/03/2007

  Project: Research

• Identifying Imprinted Genes Using Microarrays and Bioinformatics

  Oakey, R. (Primary Investigator)

  Wellcome Trust

  1/04/2004 → 4/11/2007

  Project: Research

• Predicting drug response: Investigations into the pharmacogenetic basis of the safety and efficacy of systemic therapies used in the treatment of moderate to severe psoriasis

  Smith, C. (Primary Investigator) & Solomon, E. (Primary Investigator)

  National Psoriasis Foundation

  1/04/2004 → 31/03/2006

  Project: Research

• Dissecting the pathogenesis of acute promyelocytic leukaemia

  Grimwade, D. (Primary Investigator) & Solomon, E. (Primary Investigator)

  Blood Cancer UK

  1/01/2004 → 31/12/2006

  Project: Research

• European Leukemianet (NoE)

  Grimwade, D. (Primary Investigator) & Mufti, G. (Primary Investigator)

  EC European Commission

  1/01/2004 → 28/02/2011

  Project: Research