King's College London

Research portal

Ophthalmology

Organisational unit: Department

  1. Real-time tracking of self-reported symptoms to predict potential COVID-19

    Menni, C., Valdes, A. M., Freidin, M. B., Sudre, C. H., Nguyen, L. H., Drew, D. A., Ganesh, S., Varsavsky, T., Cardoso, M. J., El-Sayed Moustafa, J. S., Visconti, A., Hysi, P., Bowyer, R. C. E., Mangino, M., Falchi, M., Wolf, J., Ourselin, S., Chan, A. T., Steves, C. J. & Spector, T. D., 11 May 2020, In : Nature Medicine.

    Research output: Contribution to journalArticle

  2. Real-world incidence of fingolimod-associated macular oedema

    Goh, L. Y., Kirthi, V., Silber, E., Harvey, J. P. & Jackson, T. L., 28 Apr 2020, In : Multiple Sclerosis and Related Disorders. 42, p. 102125

    Research output: Contribution to journalArticle

  3. Genome-wide scan identifies novel genetic loci regulating salivary metabolite levels

    Nag, A., Kurushima, Y., Bowyer, R. C. E., Wells, P. M., Weiss, S., Pietzner, M., Kocher, T., Raffler, J., Völker, U., Mangino, M., Spector, T. D., Milburn, M. V., Kastenmüller, G., Mohney, R. P., Suhre, K., Menni, C. & Steves, C. J., 27 Mar 2020, In : Human Molecular Genetics. 29, 5, p. 864-875 12 p., ddz308.

    Research output: Contribution to journalArticle

  4. Genetic Heritability of Pigmentary Glaucoma and Associations with Other Eye Phenotypes

    Simcoe, M. J., Weisschuh, N., Wissinger, B., Hysi, P. G. & Hammond, C. J., Mar 2020, In : JAMA Ophthalmology. 138, 3, p. 294-299 6 p.

    Research output: Contribution to journalArticle

  5. Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression

    NEIGHBORHOOD Consortium & UK Biobank Eye and Vision Consortium, 1 Feb 2020, In : Nature Genetics. 52, 2, p. 160-166 7 p.

    Research output: Contribution to journalArticle

  6. Appendices 1-11

    Neffendorf, J. & Jackson, T., 1 Jan 2020, Moorfields Manual of Ophthalmology. Jackson, T. (ed.). 3 ed. JP Medical Publishers, p. 755-782

    Research output: Chapter in Book/Report/Conference proceedingChapter

  7. Comparison of Associations with Different Macular Inner Retinal Thickness Parameters in a Large Cohort: The UK Biobank

    UK Biobank Eye and Vision Consortium, Khawaja, A. P., Chua, S., Hysi, P. G., Georgoulas, S., Currant, H., Fitzgerald, T. W., Birney, E., Ko, F., Yang, Q., Reisman, C., Garway-Heath, D. F., Hammond, C. J., Khaw, P. T., Foster, P. J., Patel, P. J., Strouthidis, N., Atan, D., Aslam, T., Barman, S. A. & 31 others, Barrett, J. H., Bishop, P., Blows, P., Bunce, C., Carare, R. O., Chakravarthy, U., Chan, M., Chua, S. Y. L., Crabb, D. P., Cumberland, P. M., Day, A., Desai, P., Dhillon, B., Dick, A. D., Egan, C., Ennis, S., Foster, P., Fruttiger, M., Gallacher, J. E. J., Gibson, J., Gore, D., Guggenheim, J. A., Hardcastle, A., Harding, S. P., Hogg, R. E., Hysi, P. G., Keane, P. A., Morgan, J. E., Viswanathan, A. C., Williams, K. & Zheng, Y., 1 Jan 2020, In : Ophthalmology. 127, 1, p. 62-71 10 p.

    Research output: Contribution to journalArticle

  8. Medical Retina

    Jackson, T., Egan, C., Webster, A. & Tufail, A., 1 Jan 2020, Moorfield Manual of Ophthalmology. Jackson, T. (ed.). 3 ed. JP Medical Publishers, p. 465-584

    Research output: Chapter in Book/Report/Conference proceedingChapter

  9. Accepted/In press

    Meta-analysis of 542,934 subjects of European ancestry identifies new genes and mechanisms predisposing to refractive error and myopia

    The Consortium for Refractive Error and Myopia, The UK Eye and Vision Consortium & 23andMe Inc., 1 Jan 2020, (Accepted/In press) In : Nature Genetics.

    Research output: Contribution to journalArticle

  10. Moorfields Manual of Ophthalmology

    Jackson, T. (ed.), 1 Jan 2020, 3 ed. New Delhi: JP Medical Publishers. 812 p.

    Research output: Book/ReportBook

  11. Surgical Retina

    Jackson, T. & Da Cruz, L., 1 Jan 2020, Moorfield Manual of Ophthalmology. Jackson, T. (ed.). 3 ed. JP Medical Publishers, p. 585-624

    Research output: Chapter in Book/Report/Conference proceedingChapter

  12. Low-frequency variation in TP53 has large effects on head circumference and intracranial volume

    UK10K Consortium, 1 Dec 2019, In : Nature Communications. 10, 1, 357.

    Research output: Contribution to journalArticle

  13. Multi-trait genome-wide association study identifies new loci associated with optic disc parameters

    International Glaucoma Genetics Consortium, NEIGHBORHOOD Consortium & UK Biobank Eye and Vision Consortium, 1 Dec 2019, In : Communications Biology. 2, 1, 435.

    Research output: Contribution to journalArticle

  14. Quantile regression analysis reveals widespread evidence for gene-environment or gene-gene interactions in myopia development

    UK Biobank Eye and Vision Consortium, Pozarickij, A., Williams, C., Hysi, P. G., Guggenheim, J. A., Aslam, T., Barman, S. A., Bishop, P., Blows, P., Bunce, C., Carare, R. O., Chakravarthy, U., Chan, M., Chua, S. Y. L., Crabb, D. P., Cumberland, P. M., Day, A., Desai, P., Dhillon, B., Dick, A. D. & 31 others, Egan, C., Ennis, S., Foster, P., Fruttiger, M., Gallacher, J. E. J., Garway-Heath, D. F., Gibson, J., Gore, D., Hammond, C. J., Hardcastle, A., Harding, S. P., Hogg, R. E., Keane, P. A., Khaw, S. P. T., Khawaja, A. P., Lascaratos, G., Lotery, A. J., Mac Gillivray, T., Mackie, S., Martin, K., McGaughey, M., McGuinness, B., McKay, G. J., McKibbin, M., Mitry, D., Moore, T., Muthy, Z. A., O'Sullivan, E., Owen, C. G., Patel, P. & Viswanathan, A. C., Dec 2019, In : Communications Biology. 2, 1, 167.

    Research output: Contribution to journalArticle

  15. Novel genetic loci affecting facial shape variation in humans

    International Visible Trait Genetics (VisiGen) Consortium, 26 Nov 2019, In : eLife. 8, e49898.

    Research output: Contribution to journalArticle

  16. Association of Genetic Variants with Primary Open-Angle Glaucoma among Individuals with African Ancestry

    Hauser, M. A., Allingham, R. R., Aung, T., Van Der Heide, C. J., Taylor, K. D., Rotter, J. I., Wang, S. H. J., Bonnemaijer, P. W. M., Williams, S. E., Abdullahi, S. M., Abu-Amero, K. K., Anderson, M. G., Akafo, S., Alhassan, M. B., Asimadu, I., Ayyagari, R., Bakayoko, S., Nyamsi, P. B., Bowden, D. W., Bromley, W. C. & 73 others, Budenz, D. L., Carmichael, T. R., Challa, P., Chen, Y. D. I., Chuka-Okosa, C. M., Cooke Bailey, J. N., Costa, V. P., Cruz, D. A., Dubiner, H., Ervin, J. F., Feldman, R. M., Flamme-Wiese, M., Gaasterland, D. E., Garnai, S. J., Girkin, C. A., Guirou, N., Guo, X., Haines, J. L., Hammond, C. J., Herndon, L., Hoffmann, T. J., Hulette, C. M., Hydara, A., Igo, R. P., Jorgenson, E., Kabwe, J., Kilangalanga, N. J., Kizor-Akaraiwe, N., Kuchtey, R. W., Lamari, H., Li, Z., Liebmann, J. M., Liu, Y., Loos, R. J. F., Melo, M. B., Moroi, S. E., Msosa, J. M., Mullins, R. F., Nadkarni, G., Napo, A., Ng, M. C. Y., Nunes, H. F., Obeng-Nyarkoh, E., Okeke, A., Okeke, S., Olaniyi, O., Olawoye, O., Oliveira, M. B., Pasquale, L. R., Perez-Grossmann, R. A., Pericak-Vance, M. A., Qin, X., Ramsay, M., Resnikoff, S., Richards, J. E., Schimiti, R. B., Sim, K. S., Sponsel, W. E., Svidnicki, P. V., Thiadens, A. A. H. J., Uche, N. J., Van Duijn, C. M., De Vasconcellos, J. P. C., Wiggs, J. L., Zangwill, L. M., Risch, N., Milea, D., Ashaye, A., Klaver, C. C. W., Weinreb, R. N., Ashley Koch, A. E., Fingert, J. H. & Khor, C. C., 5 Nov 2019, In : JAMA - Journal of the American Medical Association. 322, 17, p. 1682-1691 10 p.

    Research output: Contribution to journalArticle

  17. Genome-wide association analysis of 95 549 individuals identifies novel loci and genes influencing optic disc morphology

    Han, X., Qassim, A., An, J., Marshall, H., Zhou, T., Ong, J. S., Hassall, M. M., Hysi, P. G., Foster, P. J., Khaw, P. T., Mackey, D. A., Gharahkhani, P., Khawaja, A. P., Hewitt, A. W., Craig, J. E. & MacGregor, S., 1 Nov 2019, In : Human Molecular Genetics. 28, 21, p. 3680-3690 11 p.

    Research output: Contribution to journalArticle

  18. Associations with Corneal Hysteresis in a Population Cohort: Results from 96 010 UK Biobank Participants

    UKBiobank Eye and Vision Consortium, Nov 2019, In : Ophthalmology. 126, 11, p. 1500-1510 11 p.

    Research output: Contribution to journalArticle

  19. Genetic correlations between diabetes and glaucoma: an analysis of continuous and dichotomous phenotypes

    UK Biobank, International Glaucoma Genetics Consortium, NEIGHBORHOOD Consortium, 1 Oct 2019, In : American Journal of Ophthalmology. 206, p. 245-255 11 p.

    Research output: Contribution to journalArticle

  20. Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility

    International Multiple Sclerosis Genetics Consortium & ANZgene, IIBDGC, WTCCC2, 27 Sep 2019, In : Science. 365, 6460, eaav7188.

    Research output: Contribution to journalArticle

  21. Genetic Variants Associated with Corneal Biomechanical Properties and Potentially Conferring Susceptibility to Keratoconus in a Genome-Wide Association Study

    Khawaja, A. P., Rojas Lopez, K. E., Hardcastle, A. J., Hammond, C. J., Liskova, P., Davidson, A. E., Gore, D. M., Hafford Tear, N. J., Pontikos, N., Hayat, S., Wareham, N., Khaw, K. T., Tuft, S. J., Foster, P. J. & Hysi, P. G., 1 Sep 2019, In : JAMA Ophthalmology. 137, 9, p. 1005-1012 8 p.

    Research output: Contribution to journalArticle

  22. The European Eye Epidemiology spectral-domain optical coherence tomography classification of macular diseases for epidemiological studies

    the European Eye Epidemiology (E3) consortium, Jun 2019, In : Acta Ophthalmologica. 97, 4, p. 364-371 8 p.

    Research output: Contribution to journalArticle

  23. High myopia and its risks

    Williams, K. & Hammond, C., 1 May 2019, In : Community Eye Health Journal. 32, 105, p. 5-6 2 p.

    Research output: Contribution to journalArticle

  24. Cohort profile: Design and methods in the eye and vision consortium of UK Biobank

    UK Biobank Eye and Vision Consortium, 1 Feb 2019, In : BMJ Open. 9, 2, e025077.

    Research output: Contribution to journalReview article

  25. Development of Targeted siRNA Nanocomplexes to Prevent Fibrosis in Experimental Glaucoma Filtration Surgery

    Fernando, O., Tagalakis, A. D., Awwad, S., Brocchini, S., Khaw, P. T., Hart, S. L. & Yu-Wai-Man, C., 5 Dec 2018, In : Molecular Therapy. 26, 12, p. 2812-2822 11 p.

    Research output: Contribution to journalArticle

  26. In vitro and in vivo delivery of a sustained release nanocarrier-based formulation of an MRTF/SRF inhibitor in conjunctival fibrosis

    Tagalakis, A. D., Madaan, S., Larsen, S. D., Neubig, R. R., Khaw, P. T., Rodrigues, I., Goyal, S., Lim, K. S. & Yu-Wai-Man, C., 27 Nov 2018, In : Journal of Nanobiotechnology. 16, 1, 97.

    Research output: Contribution to journalArticle

  27. Repeatability of the macular pigment spatial profile: A comparison of objective versus subjective classification

    Ctori, I., Mahroo, O. A., Williams, K. M., Hammond, C. J. & Huntjens, B., Nov 2018, In : Acta Ophthalmologica. 96, 7, p. e797-e803

    Research output: Contribution to journalArticle

  28. Increased High Density Lipoprotein-levels associated with Age-related Macular degeneration. Evidence from the EYE-RISK and E3 Consortia

    Colijn, J. M., Hollander, A. I. D., Demirkan, A., Cougnard-Grégoire, A., Verzijden, T., Kersten, E., Meester, M. A., Merle, B. M. J., Papageorgiou, G., Ahmad, S., Mulder, M. T., Costa, M. A., Benlian, P., Bertelsen, G., Bron, A., Claes, B., Creuzot-Garcher, C., Erke, M. G., Fauser, S., Foster, P. J. & 13 others, Hammond, C. J., Hense, H. W., Hoyng, C. B., Khawaja, A. P., Korobelnik, J., Piermarocchi, S., Segato, T., Silva, R., Souied, E. H., Williams, K. M., van Duijn, C. M., Delcourt, C. & Klaver, C. C. W., 10 Oct 2018, In : Ophthalmology.

    Research output: Contribution to journalArticle

  29. Genome-wide association study of primary open-angle glaucoma in continental and admixed African populations

    GIGA Study Group, Oct 2018, In : Human Genetics. 137, 10, p. 847-862 16 p.

    Research output: Contribution to journalArticle

  30. The Decreasing Prevalence of Nonrefractive Visual Impairment in Older Europeans: A Meta-analysis of Published and Unpublished Data

    European Eye Epidemiology Consortium, Aug 2018, In : Ophthalmology. 125, 8, p. 1149-1159 11 p.

    Research output: Contribution to journalArticle

  31. Genome-wide analyses identify 68 new loci associated with intraocular pressure and improve risk prediction for primary open-angle glaucoma

    NEIGHBORHOOD Consortium, Khawaja, A. P., Cooke Bailey, J. N., Wareham, N. J., Scott, R. A., Simcoe, M., Igo, R. P., Song, Y. E., Wojciechowski, R., Cheng, C. Y., Khaw, P. T., Pasquale, L. R., Haines, J. L., Foster, P. J., Wiggs, J. L., Hammond, C. J. & Hysi, P. G., 21 May 2018, In : Nature Genetics. 50, 6, p. 778–782 5 p., EMSSID # 76895.

    Research output: Contribution to journalLetter

  32. Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases

    Blue Mountains Eye Study—GWAS group, Iglesias, A. I., Mishra, A., Vitart, V., Bykhovskaya, Y., Höhn, R., Springelkamp, H., Cuellar-Partida, G., Gharahkhani, P., Bailey, J. N. C., Willoughby, C. E., Li, X., Yazar, S., Nag, A., Khawaja, A. P., Polašek, O., Siscovick, D., Mitchell, P., Tham, Y. C., Haines, J. L. & 31 others, Kearns, L. S., Hayward, C., Shi, Y., van Leeuwen, E. M., Taylor, K. D., Bonnemaijer, P., Rotter, J. I., Martin, N. G., Zeller, T., Mills, R. A., Staffieri, S. E., Jonas, J. B., Schmidtmann, I., Boutin, T., Kang, J. H., Lucas, S. E. M., Wong, T. Y., Beutel, M. E., Wilson, J. F., Uitterlinden, A. G., Vithana, E. N., Foster, P. J., Hysi, P. G., Hewitt, A. W., Khor, C. C., Pasquale, L. R., Montgomery, G. W., Klaver, C. C. W., Aung, T., Pfeiffer, N. & Hammond, C. J., 14 May 2018, In : Nature Communications. 9, 1, p. 1864

    Research output: Contribution to journalArticle

  33. Systemic and Ocular Determinants of Peripapillary Retinal Nerve Fiber Layer Thickness Measurements in the European Eye Epidemiology (E3) Population

    European Eye Epidemiology (E3) Consortium, Mauschitz, M. M., Bonnemaijer, P. W. M., Diers, K., Rauscher, F. G., Elze, T., Engel, C., Loeffler, M., Colijn, J. M., Ikram, M. A., Vingerling, J. R., Williams, K. M., Hammond, C. J., Creuzot-Garcher, C., Bron, A. M., Silva, R., Nunes, S., Delcourt, C., Cougnard-Grégoire, A., Holz, F. & 3 others, Klaver, C., Breteler, M. M. B. & Finger, R. P., 30 Apr 2018, In : Ophthalmology.

    Research output: Contribution to journalArticle

  34. Automated quantification of retinal vessel morphometry in the UK biobank cohort

    on behalf of the UK Biobank Eye and Vision Consortium, 8 Mar 2018, Proceedings of the 7th International Conference on Image Processing Theory, Tools and Applications, IPTA 2017. Institute of Electrical and Electronics Engineers Inc., p. 1-6 6 p. (Proceedings of the 7th International Conference on Image Processing Theory, Tools and Applications, IPTA 2017; vol. 2018-January).

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  35. Intravitreal gas for symptomatic vitreomacular adhesion: a synthesis of the literature

    Neffendorf, J. E., Simpson, A. R. H., Steel, D. H. W., Desai, R., McHugh, D. A., Pringle, E. & Jackson, T. L., 31 Aug 2017, In : Acta Ophthalmologica.

    Research output: Contribution to journalArticle

  36. Phenotypic and genotypic correlation between myopia and intelligence

    Williams, K. M., Hysi, P. G., Yonova-Doing, E., Mahroo, O. A., Snieder, H. & Hammond, C. J., 6 Apr 2017, In : Scientific Reports. 7, p. 45977

    Research output: Contribution to journalArticle

  37. New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics

    Springelkamp, H., Iglesias, A. I., Mishra, A., Höhn, R., Wojciechowski, R., Khawaja, A. P., Nag, A., Wang, Y. X., Wang, J. J., Cuellar-Partida, G., Gibson, J., Cooke Bailey, J. N., Vithana, E. N., Gharahkhani, P., Boutin, T., Ramdas, W. D., Zeller, T., Luben, R. N., Yonova-Doing, E., Viswanathan, A. C. & 64 others, Yazar, S., Cree, A. J., Haines, J. L., Koh, J. Y., Souzeau, E., Wilson, J. F., Amin, N., Müller, C., Venturini, C., Kearns, L. S., Hee Kang, J., Consortium, N., Tham, Y. C., Zhou, T., van Leeuwen, E. M., Nickels, S., Sanfilippo, P., Liao, J., Linde, H. V. D., Zhao, W., van Koolwijk, L. M. E., Zheng, L., Rivadeneira, F., Baskaran, M., van der Lee, S. J., Perera, S., de Jong, P. T. V. M., Oostra, B. A., Uitterlinden, A. G., Fan, Q., Hofman, A., Shyong Tai, E., Vingerling, J. R., Sim, X., Wolfs, R. C. W., Teo, Y. Y., Lemij, H. G., Khor, C. C., Willemsen, R., Lackner, K. J., Aung, T., Jansonius, N. M., Montgomery, G., Wild, P. S., Young, T. L., Burdon, K. P., Hysi, P. G., Pasquale, L. R., Wong, T. Y., Klaver, C. C. W., Hewitt, A. W., Jonas, J. B., Mitchell, P., Lotery, A. J., Foster, P. J., Vitart, V., Pfeiffer, N., Craig, J. E., Mackey, D. A., Hammond, C. J., Wiggs, J. L., Cheng, C-Y., van Duijn, C. M. & MacGregor, S., 10 Jan 2017, In : Human Molecular Genetics. 26, 2, p. 438-453

    Research output: Contribution to journalArticle

  38. StereoTactic radiotherapy for wet Age-Related macular degeneration (STAR): Study protocol for a randomised controlled clinical trial

    Neffendorf, J. E., Desai, R., Wang, Y., Kelly, J., Murphy, C., Reeves, B. C., Chakravarthy, U., Wordsworth, S., Lewis, C., Peacock, J., Uddin, S., O'Sullivan, J. M. & Jackson, T. L., 24 Nov 2016, In : Trials. 17, 1, 560.

    Research output: Contribution to journalArticle

  39. Genetic and Dietary Factors Influencing the Progression of Nuclear Cataract

    Yonova-Doing, E., Forkin, Z. A., Hysi, P., Williams, K. M., Spector, T. D., Gilbert, C. & Hammond, C. J., Jun 2016, In : Ophthalmology. 123, 6

    Research output: Contribution to journalArticle

  40. Epimacular Brachytherapy for Previously Treated Neovascular Age-Related Macular Degeneration (MERLOT): A Phase 3 Randomized Controlled Trial

    Jackson, T. L., Desai, R., Simpson, A., Neffendorf, J. E., Petrarca, R., Smith, K., Wittes, J., Lewis, C., Membrey, L., Haynes, R., Costen, M., Steel, D. H. W., Muldrew, A. & Chakravarthy, U., 13 Apr 2016, In : Ophthalmology.

    Research output: Contribution to journalArticle

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