Peter Gorer Department of Immunobiology

Finished

Cooperative harmonization and validation of an islet-specific AIM assay

Tree, T. (Primary Investigator)

1/02/2024 → 31/01/2025

Project: Research

A multiphoton confocal microscope for deep tissue imaging in live organism

Denk, F. (Primary Investigator), Bafadhel, M. (Co-Investigator), Bannister, K. (Co-Investigator), Bradbury, E. (Co-Investigator), Cleary, S. (Co-Investigator), Ivetic, A. (Co-Investigator), Levitt, J. (Co-Investigator), Parsons, M. (Co-Investigator), Pitchford, S. (Co-Investigator), Shaw, T. (Co-Investigator), Stramer, B. (Co-Investigator) & Warnatsch, A. (Co-Investigator)

BBSRC Biotechnology and Biological Sciences Research Council

1/08/2023 → 31/07/2024

Project: Research

Engineering third generation Tregs for the treatment of sensitised kidney transplant patients

Lombardi, G. (Primary Investigator), Dorling, A. (Co-Investigator), Sanchez Fueyo, A. (Co-Investigator) & Scotta, C. (Co-Investigator)

Rosetrees Trust

1/02/2023 → 20/08/2024

Project: Research

Creating new opportunities for highly sensitised patients waiting for a kidney transplant

Lombardi, G. (Primary Investigator) & Scotta, C. (Co-Investigator)

MRC Medical Research Council

1/01/2023 → 20/08/2024

Project: Research

BHF Centre Lombardi pump-prime

Lombardi, G. (Primary Investigator)

BHF British Heart Foundation

1/01/2023 → 30/09/2024

Project: Research

CAPTAIN-15: CAncer Of The Prostate -IntraTumoural Administration Of INterleukin-15 (CAPTAIN-15) - A First-in Man Phase 1 Safety And Efficacy Trial In Prostate Cancer Patients

Galustian, C. (Primary Investigator), Cook, G. (Co-Investigator), Dasgupta, P. (Co-Investigator) & academic, A. (Co-Investigator)

Lotto LR S.R.L

1/11/2022 → 31/12/2024

Project: Research

Improvement of Robotic-assisted Radical Prostatectomy Outcomes via Automatically-segmented 3D-printed Prostate Models: a feasibility Study

Granados Martinez, A. (Primary Investigator), Dasgupta, P. (Co-Investigator) & Ourselin, S. (Co-Investigator)

Urology Foundation

1/08/2022 → 31/10/2024

Project: Research

Immunogenicity of proteasome-generated spliced peptides derived from fusion-genes in childhood acute and chronic myeloid leukaemia

Mishto, M. (Primary Investigator) & Dillon, R. (Co-Investigator)

CRUK Cancer Research UK

1/08/2022 → 31/07/2023

Project: Research

Development of an in-body cell therapy treatment using nanoparticles

Kochl, R. (Primary Investigator)

TSB Technology Strategy Board

1/06/2022 → 31/03/2024

Project: Research

Engineering regulatory T cells (Tregs) to modulate kidney injury and prevent renal fibrosis

Lombardi, G. (Primary Investigator), Peng, Q. (Co-Investigator), Safinia, N. (Co-Investigator), Sanchez Fueyo, A. (Co-Investigator) & Sharpe, C. (Co-Investigator)

KIDNEY RESEARCH UK

7/05/2022 → 31/07/2024

Project: Research

Wellcome/EPSRC Centre for Medical Engineering Extension

Ourselin, S. (Primary Investigator), Barker, G. (Co-Investigator), Barnes, A. (Co-Investigator), Barrington, S. (Co-Investigator), Bergeles, C. (Co-Investigator), Bishop, M. (Co-Investigator), Blower, P. (Co-Investigator), Booth, T. (Co-Investigator), Botnar, R. (Co-Investigator), Cardoso, J. (Co-Investigator), Carmichael, D. (Co-Investigator), Chiribiri, A. (Co-Investigator), Clough, R. (Co-Investigator), Cook, G. (Co-Investigator), Counsell, S. (Co-Investigator), Dasgupta, P. (Co-Investigator), De Vecchi, A. (Co-Investigator), De Vita, E. (Co-Investigator), Edwards, D. (Co-Investigator), Goh, V. (Co-Investigator), Hajnal, J. (Co-Investigator), Hammers, A. (Co-Investigator), Hutter, J. (Co-Investigator), Ipek, O. (Co-Investigator), King, A. (Co-Investigator), Lamata de la Orden, P. (Co-Investigator), Liu, H. (Co-Investigator), Malik, S. (Co-Investigator), Marsden, P. (Co-Investigator), Modat, M. (Co-Investigator), Niederer, S. (Co-Investigator), Razavi, R. (Co-Investigator), Reader, A. (Co-Investigator), Rhode, K. (Co-Investigator), Roujol, S. (Co-Investigator), Rutherford, M. (Co-Investigator), Shapey, J. (Co-Investigator), Sparks, R. (Co-Investigator), T. M. de Rosales, R. (Co-Investigator), Terry, S. (Co-Investigator), Tournier, J.-D. (Co-Investigator), Vercauteren, T. (Co-Investigator), Williams, S. (Co-Investigator), Xia, W. (Co-Investigator), Young, A. (Co-Investigator) & academic, A. (Co-Investigator)

Wellcome Trust

28/04/2022 → 27/10/2024

Project: Research

CD204: PILOT STUDY - Targeting macrophage scavenger receptor CD204 in solid tumours

Mukhopadhyay, S. (Primary Investigator)

CRUK Cancer Research UK

1/03/2022 → 31/05/2023

Project: Research

Optimization of the potency, specificity and survival properties of engineered regulatory T cells to treat inflammatory liver diseases

Sanchez Fueyo, A. (Primary Investigator), Fruhwirth, G. (Co-Investigator), Lombardi, G. (Co-Investigator) & Safinia, N. (Co-Investigator)

Rosetrees Trust

1/12/2021 → 30/11/2024

Project: Research

Aspergillus and chronic lung allograft dysfunction: an immunophenotyping approach to optimise therapies

Hayday, A. (Primary Investigator)

MRC Medical Research Council

1/11/2021 → 31/10/2024

Project: Research

Generation of Liver-Immune Double Chimeric Humanised Mouse Models: A Platform for Simultaneous Assessment of Function and Immunogenicity of Liver-Specific Cellular Therapies

Lombardi, G. (Primary Investigator)

MRC Medical Research Council

1/10/2021 → 20/02/2023

Project: Research

Imaging Mass cytometry to delineate cutaneous immune cell populations

Spencer, J. (Primary Investigator)

GSTT Guy's and St Thomas' NHS Foundation Trust

20/08/2021 → 19/08/2022

Project: Research

Evaluation of potency of CAR-T cells produced by ImmTune’s in vivo gene delivery technology (NanoCART)

Kochl, R. (Primary Investigator)

Research England

1/08/2021 → 31/05/2022

Project: Research

Development of a multimodal image guided surgical tool for prostate cancer.

Stasiuk, G. (Primary Investigator), Cook, G. (Co-Investigator), Dasgupta, P. (Co-Investigator), Goh, V. (Co-Investigator), Ourselin, S. (Co-Investigator) & Prezzi, D. (Co-Investigator)

MRC Medical Research Council

1/06/2021 → 31/05/2022

Project: Research

CARDINNATE: Variation in innate immune activation and cardiovascular disease risk as drivers of COVID19 outcome in South Asians in UK and India

Hayday, A. (Primary Investigator), Neil, S. (Co-Investigator) & Shah, A. (Co-Investigator)

MRC Medical Research Council

7/05/2021 → 31/12/2024

Project: Research

Simultaneous quantification and localization of mRNA and proteins at (sub)cellular resolution in cancer samples treated with immunotherapy

Ciccarelli, F. (Primary Investigator), Kordasti, S. (Co-Investigator) & Spencer, J. (Co-Investigator)

CRUK Cancer Research UK

1/04/2021 → 31/03/2022

Project: Research

Project to measure the impact of mAbs

Sacks, S. (Primary Investigator) & Douiri, A. (Co-Investigator)

MRC Medical Research Council

1/04/2021 → 31/07/2022

Project: Research

Regulation of macrophage activation

Mukhopadhyay, S. (Primary Investigator)

Royal Society

31/03/2021 → 28/02/2022

Project: Research

Targeting the Complement system - alveolar epithelial response to COVID-19 with Mirococept

Sacks, S. (Primary Investigator), Klavinskis, L. (Co-Investigator) & Polycarpou, A. (Co-Investigator)

BSAC British Society for Antimicrobial Chemotherapy

4/01/2021 → 3/01/2024

Project: Research

UKRI CoA: Checkpoint for B cell survival in human gut

Spencer, J. (Primary Investigator)

EPSRC Engineering and Physical Sciences Research Council

1/01/2021 → 30/06/2021

Project: Research

CAR-Treg therapy in metabolic and inflammatory disorders: Targeting the Nrf2/HO-1 pathway

Safinia, N. (Primary Investigator) & Lombardi, G. (Co-Investigator)

MRC Medical Research Council

1/11/2020 → 12/07/2022

Project: Research

CD1d AS A NOVEL REGULATOR OF INNATE IMMUNITY

Barral, P. (Primary Investigator)

BBSRC Biotechnology and Biological Sciences Research Council

1/10/2020 → 30/09/2023

Project: Research

Regulatory T cells in Highly Sensitised Renal Patients to Improve Outcomes after HLA-Ab Incompatible Transplantation

Dorling, A. (Primary Investigator), Bunce, C. (Co-Investigator), Lombardi, G. (Co-Investigator), Sanchez Fueyo, A. (Co-Investigator) & Robinson, E. (Co-Investigator)

MRC Medical Research Council

30/09/2020 → 29/05/2024

Project: Research

Trusted Autonomous Systems Hub

Moreau, L. (Primary Investigator), Borgo, R. (Co-Investigator), Ventre, C. (Co-Investigator), Chockler, H. (Co-Investigator), Viganò, L. (Co-Investigator), Devlin, K. (Co-Investigator), Kleinman, M. (Co-Investigator), Aplin, T. (Co-Investigator), Luff, P. (Co-Investigator), Samiolo, R. (Co-Investigator) & Dasgupta, P. (Co-Investigator)