Peter Gorer Department of Immunobiology

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• Why Do Vaccines Fail the Elderly?

  Martin, V. G. (Author), Dunn-Walters, D. K. (Supervisor) & John, S. (Supervisor), 2014

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Why do vaccines fail the elderly

  Martin, V. (Author), Dunn-Walters, D. K. (Supervisor) & John, S. (Supervisor), 2014

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Understanding the molecular basis for T- cell induced pro and anti-inflammatory functions of monocytes

  Dickinson, A. K. (Author), Taams, L. (Supervisor), Guermonprez, P. (Supervisor) & Geissmann, F. H. L. (Supervisor), 1 May 2019

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Understanding the impact of a common IL2RA polymorphism on immune phenotype and function in inflammatory bowel disease

  Clough, J. (Author), Irving, P. (Supervisor) & Lord, G. M. (Supervisor), 1 Aug 2024

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Understanding B Cells in Health and Systemic Lupus Erythematosus

  Velounias, R. (Author), Spencer, J. (Supervisor) & D’Cruz, D. (Supervisor), 1 Aug 2023

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Tissue-specific butyrophilin-like proteins are γδTCR selecting ligands distinct from antigens

  Zlatareva, I. (Author), Hayday, A. (Supervisor) & Arnold, J. (Supervisor), 1 Jul 2020

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The γδ T Cell receptor mediates local epithelium-t cell communication in the gut

  Melandri, D. (Author), Hayday, A. (Supervisor) & Spencer, J. (Supervisor), 1 May 2020

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The Role of Transitional B cells in Kidney Transplantation Tolerance

  Nova Lamperti, E. (Author), Lombardi, G. (Supervisor) & Hernandez Fuentes, M. P. (Supervisor), 1 Mar 2014

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The Role of the RNA Binding Proteins ZFP36L1 and ZFP36L2 in Glucocorticoid Regulation and Disease Pathobiology in Severe Asthma

  Rynne, J. (Author), Martinez Nunez, R. (Supervisor), Hawrylowicz, C. (Supervisor) & Edwards, M. (Supervisor), 1 Feb 2022

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The role of retinoic acid in the regulation of T helper welfare

  Brown, C. C. M. (Author), Lord, G. M. (Supervisor), 2018

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The role of microRNAs in T helper cell function and differentiation

  Atalar, K. B. (Author), 2012

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The role of interleukin 22 in human colonic inflammation

  Pavlidis, P. (Author), Powell, N. (Supervisor), Lombardi, G. (Supervisor) & Hayee, B. (Supervisor), 2018

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The Role of Disease-Linked Genetic Variation in the Regulation of Gene Transcription

  Soderquest, K. (Author), Lord, G. M. (Supervisor) & Trembath, R. C. (Supervisor), 2013

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The role of CD8: B-lymphocyte interactions in type 1 diabetes pathogenesis

  Hanton, E. (Author), Peakman, M. (Supervisor), Liu, Y.-F. (Supervisor) & Tree, T. (Supervisor), 1 Sept 2021

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The role of B cells in the amplification and in the regulation of transplant rejection.

  Alhabbab, R. (Author), Blair, P. A. (Supervisor), Lombardi, G. (Supervisor) & Lechler, R. I. (Supervisor), 1 Feb 2013

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The phenotypic and functional characterisation of regulatory T-cells from patiends with end stage liver disease; : Implications for adoptive cell therapy

  Safinia, N. (Author), Lombardi, G. (Supervisor) & Lechler, R. I. (Supervisor), 2014

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The pancreatic β-cell zinc response to chronic stimulation and extracellular zinc depletion 

  Lawson, R. S. (Author), Hogstrand, C. (Supervisor), Peakman, M. (Supervisor) & Maret, W. (Supervisor), 2019

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The ontogeny of inflammatory macrophages and monocyte-derived dendritic cells.

  Menezes, S. G. (Author), Guermonprez, P. (Supervisor) & Lombardi, G. (Supervisor), 2017

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The Multi-Institutional Validation and Assessment of Training Modalities in Robotic Surgery: The MARS Project

  Raison, N. (Author), Dasgupta, P. (Supervisor) & Ahmed, K. (Supervisor), 1 Apr 2021

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The in vitro transcriptional regulation of interleukin-10 versus pro-inflammatory cytokine gene expression by c-Maf and Blimp-1 in CD4⁺ T-helper cells

  Cox, L. (Author), O'Garra, A. (Supervisor) & Hawrylowicz, C. (Supervisor), 1 Mar 2020

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• The Human Colonic γδ T cell Compartment and its Regulation by Butyrophilin-like Molecules in Health and Inflammatory Bowel Disease

  Dart, R. J. C. (Author), Hayday, A. (Supervisor) & Peakman, M. (Supervisor), 1 Jul 2019

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• The Generation of MHC Class I Restricted Islet Antigen Specific Regulatory T Cells for the Treatment of Type 1 Diabetes

  Nickolay, L. E. (Author), Peakman, M. (Supervisor) & Tree, T. I. M. (Supervisor), 2015

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The effects of Low-dose IL-2 immunotherapy on immune cells in Amyotrophic Lateral Sclerosis – an incurable motor neuron disease with immune driven pathologies

  Mickunas, M. (Author), Tree, T. (Supervisor) & Peakman, M. (Supervisor), 1 Nov 2021

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The control of T cell functionality in the human neonate

  Gee, S. (Author), Gibbons, D. (Supervisor) & Lavender, P. (Supervisor), 1 Sept 2022

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• T Follicular Helper Cells in Health and Inflammatory Bowel Disease

  Thomas, J. (Author), Spencer, J. M. (Supervisor) & Sanderson, J. (Supervisor), 2013

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Study of the reactivity of a monoclonal antibody that recognises human marginal zone B cells and a subset of germinal centre cells in tissue sections

  Alyafei, S. A. M. M. (Author), Spencer, J. (Supervisor), 2018

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Role of BCL11A in germinal centre B cell biology and differentiation

  Gabrysiak, M. (Author), Calado, D. (Supervisor) & Devereux, S. (Supervisor), 1 Feb 2020

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Processing and presentation of hybrid polypeptides in type 1 diabetes

  Harbige, J. (Author), Peakman, M. (Supervisor), Tree, T. (Supervisor) & Mishto, M. (Supervisor), 1 Sept 2020

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Next-generation CAR-Tregs for their clinical translation in the induction of tolerance in transplantation and autoimmune disease

  Saleem, A. (Author), Fruhwirth, G. (Supervisor) & Lombardi, G. (Supervisor), 1 Oct 2023

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• MYC/MIZ1 complex formation is essential in development of aggressive Germinal Center-derived lymphomas

  Gunawan, A. (Author), Calado, D. (Supervisor) & Spencer, J. (Supervisor), 1 Sept 2022

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Molecular mechanisms that drive functional imbalance of circulating CD4+ T cell subsets in granulomatosis with polyangiitis patients

  Kim, S. (Author), John, S. (Supervisor) & D'Cruz, D. (Supervisor), 1 May 2020

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Modulation of the murine lymphatic system to decipher its role in the allo-immune response

  Meader, L. (Author), Lombardi, G. (Supervisor) & Wong, W. (Supervisor), 2018

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Mental Wellbeing in Prostate Cancer Treatment and Survivorship: Outcome Definition, Prognostic Factors, and Prognostic Model Development

  Brunckhorst, O. (Author), Ahmed, K. (Supervisor), Dasgupta, P. (Supervisor) & Stewart, R. J. (Supervisor), 1 Mar 2024

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Mechanisms of action of peptide immunotherapy for Type 1 diabetes: characterising T cells induced or modified by proinsulin.

  Liu, Y.-F. (Author), Peakman, M. (Supervisor) & Powrie, J. (Supervisor), 1 Feb 2018

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Mechanisms of action of peptide immunotherapy for Type 1 diabetes: Characterising T-cells induced or modified by proinsulin C19-A3

  Liu, Y.-F. (Author), Peakman, M. (Supervisor), 2018

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• LPS responses of primary myeloid cells in vitro and in vivo in peritoneal cavity cells and their modulation by type I IFN

  Alvarez Martinez, M. (Author), O'Garra, A. (Supervisor) & Hawrylowicz, C. (Supervisor), 1 Sept 2023

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Low Dose Intradermal Allergen Immunotherapy in Treatment of Seasonal Allergic Rhinitis

  Slovick, A. (Author), Till, S. (Supervisor), Durham, S. (Supervisor) & Hopkins, C. (Supervisor), 1 Jun 2023

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Jak-stat pathway in the control of mycobacterial infections

  Pean, C. (Author), Dionne, M. S. (Supervisor) & Hayday, A. C. (Supervisor), 1 Dec 2013

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• In vivo imaging of regulatory T cell mediated transplant tolerance

  Sharif-Paghaleh, E. (Author), Lombardi, G. (Supervisor) & Mullen, G. E. D. (Supervisor), 2012

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Investigation of the functional reactivation of memory B cells in allergy and disease

  Moore, T. (Author), Spencer, J. M. (Supervisor) & Fear, D. J. (Supervisor), 1 Nov 2022

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Investigating the role of the protein tyrosine phosphatase non-receptor type 22 (PTPN22) in Fcγ receptor signalling in myeloid cells

  Clarke, F. (Author), Cope, A. (Supervisor) & Guermonprez, P. (Supervisor), 1 Aug 2019

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Investigating the Role of Defined Microbes in Modulating Skin Immune Responses

  Suen, V. M. (Author), Lombardi, G. (Supervisor) & Nestle, F. (Supervisor), 2018

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Investigating the impact of ovarian carcinoma ascites on Toll-like receptor mediated dendritic cell activation

  Brencicova, E. (Author), Diebold, S. S. (Supervisor) & Taams, L. S. (Supervisor), 2013

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Investigating the expression and function of IL-17A+ and IL-17F+ CD4+ T cells in human health and inflammatory arthritis

  Burns, L. A. (Author), Taams, L. (Supervisor), 1 Jun 2019

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Investigating non-classical functions of CD1d: regulation of TLR function and lipid homeostasis

  Brailey, P. (Author), Barral, P. (Supervisor), 1 Oct 2021

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Investigating molecular crosstalk between PLCγ1 and STAT3 in Cutaneous T-Cell Lymphoma

  Campbell, V. (Author), Mitchell, T. (Supervisor) & John, S. (Supervisor), 1 Jan 2025

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Investigating immune responses in HORMAD1-positive tumours

  Chen, L. (Author), Grigoriadis, A. (Supervisor) & Hayday, A. (Supervisor), 1 Jul 2020

  Student thesis: Master's Thesis › Master of Philosophy

• Investigating BET proteins as a therapeutic target in keloid scarring

  Bell, R. E. (Author), Shaw, T. J. (Supervisor) & Dionne, M. S. (Supervisor), 2018

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Interaction between Wnt and Androgen Receptor (AR) signalling pathways in prostate cancer

  Khan, R. A. (Author), Ahmed, A. (Supervisor) & Dasgupta, P. (Supervisor), 1 May 2022

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Inflammatory cytokines compromise programmed cell death-1 (PD-1)-mediated T cell suppression in inflammatory arthritis through up-regulation of soluble PD-1.

  Bommarito, D. (Author), Corrigall, V. M. (Supervisor) & Taams, L. S. (Supervisor), 2018

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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