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Pharmaceutical Sciences Clinical Academic Group

Organisational unit: Clinical Academic Group

Organisation profile

 

The Pharmaceutical Sciences Clinical Academic Group (PSCAG), part of King’s Health Partners, comprises three of the UK’s leading trust pharmacy departments, Guy’s and St Thomas’ NHS Foundation Trust (GSTFT), King’s College Hospital Foundation Trust (KCHFT) and the South London and Maudsley NHS Foundation Trust (SLaMFT), the Institute of Pharmaceutical Science (IPS) at King’s College London and the Quintiles Drug Research Unit at Guy’s.  Of the 1600 people in PSCAG, there are many pharmacists (most of whom are qualified at least to Master’s level) and significant numbers of scientists, medical doctors, pharmacy technicians, pharmacy/pharmacology students (undergraduate and postgraduate) and administrative and support staff.

Guy’s and St Thomas’ NHS Foundation Trust

The pharmacy department at GSTFT provides dispensing services from Guy’s and St Thomas’ and a full clinical pharmacy service to wards and departments.  In addition to meeting the pharmaceutical care needs of the 750,000 patients who use Guy’s and St Thomas’ each year, the pharmacy is also home to two ‘regional’ pharmacy specialties, Medicines Information and Pharmacy Quality Assurance.  It also incorporates a sterile manufacturing unit, and a non-sterile, licensed manufacturing unit.  Dispensing is automated on the St Thomas’ site and e-Prescribing is being evaluated on three wards.  A clinical trials supplies unit is closely linked to the manufacturing departments.  The specialist pharmacists supporting the South East London Cancer Network are also based within the Guy’s and St Thomas’ pharmacy.

King’s College Hospital Foundation Trust

The pharmacy department at KCHFT provides dispensing services from King’s College Hospital and a full clinical pharmacy service based on the clinical specialist model to the 950 inpatient beds and associated outpatient clinics of the hospital.  It incorporates a licensed sterile manufacturing unit and a clinical trials supplies unit (maintaining 150 medicines trials).  E-prescribing is well established.  Medicines Information is provided from Guy’s.  King’s College Hospital pharmacy is a UK leader in innovative methods of assuring patient safety in respect to medicines.

South London and Maudsley NHS Foundation Trust

The pharmacy department at SLaMFT provides dispensing services from three hospitals (Maudsley, Lambeth and Bethlem Royal) and a clinical pharmacy service to 1000 in-patients and 3000 community patients.  The Medicines Information centre at the Maudsley is the national centre for information on psychotropics.  The South London and Maudsley pharmacy produces the Maudsley Prescribing Guidelines which is the standard text for prescribing advise in most countries.  E-prescribing is under development with a pilot planned.

Institute of Pharmaceutical Science

Staff in the IPS at King’s College London have considerable research strengths in drug delivery and formulation science, pharmacology and clinical pharmacology, analytical science and medicinal chemistry (including molecular modelling). Research centres around the following themes: clinical practice and medication use; drug delivery (e.g. dermal, transdermal, pulmonary, gastrointestinal); synthetic chemistry (drug discovery); chemical biology; pharmaceutical biophysics; and pharmacology and therapeutics (lung biology, pulmonary pharmacology, blood brain barrier).  Staff within Institute also provide substantial teaching to undergraduate programmes as well as to postgraduate taught programmes. They also supervise a range of PhD projects.

Quintiles Drug Research Unit

The Quintiles Drug Research Unit at Guy’s carries out commercially sponsored Phase I/II studies of investigational drugs, including first-in-man studies.  Quintiles GDRU is a global company with offices in over 50 countries and headquarters in North Carolina, USA.  Quintiles GDRU has over 20 years experience in translational medicine and has performed ‘first in human’ studies with over 400 new small molecules and biologics.  The unit is recognised internationally for its expertise in preclinical and regulatory strategy combined with innovative Phase 1 study design.  Since its inception, Quintiles GDRU has established a collaboration with senior clinical and academic staff from King’s College London and Guy’s and St Thomas’ NHS Foundation Trust, in order to obtain specialist advice and practical, expert input covering many therapeutic areas.  This has involved consultants in allergy, anaesthetics, cardiology, dermatology, immunology, respiratory medicine, gastroenterology, haematology, microbiology, nephrology, neurology, psychiatry, rheumatology and urology.

Pharmaceutical Sciences Clinical Academic Group

The PSCAG is led by Professor David Taylor, who is Professor of Psycho-pharmacology at King’s College London and Director of Pharmacy and Pathology at SLaM.  The aim of the PSCAG is to integrate the work of staff across all partner organisations to improve practice, research and education. In particular, it is a key strategic objective to assure translation of research findings into practice as quickly as possible.

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