Research output per year
Research output per year
Research output
- 1 - 50 out of 2,511 results
Search results
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2024
Accelarated immune ageing is associated with COVID-19 disease severity
on behalf of the PHOSP-COVID Study collaborative group & ISARIC4C Investigators, 11 Jan 2024, (E-pub ahead of print) In: Immunity and Ageing. 21, 1, 6.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Acinar-ductal cell rearrangement drives branching morphogenesis of the murine pancreas in an IGF/PI3K-dependent manner
Darrigrand, J-F., Salowka, A., Torres-Cano, A., Tapia-Rojo, R., Zhu, T., Garcia-Manyes, S. & Spagnoli, F. M., 5 Feb 2024, In: Developmental Cell. 59, 3, p. 326-338.E5Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Age-specific and compartment-dependent changes in mitochondrial homeostasis and cytoplasmic viscosity in mouse peripheral neurons
Sleigh, J. N., Mattedi, F., Richter, S., Annuario, E., Ng, K., Steinmark, I. E., Ivanova, I., Darabán, I. L., Joshi, P. P., Rhymes, E. R., Awale, S., Yahioglu, G., Mitchell, J. C., Suhling, K., Schiavo, G. & Vagnoni, A., 17 Jun 2024, (E-pub ahead of print) In: AGING CELL.Research output: Contribution to journal › Article › peer-review
Open Access -
A palmitoyl transferase chemical–genetic system to map ZDHHC-specific S-acylation
Ocasio, C. A., Baggelaar, M. P., Sipthorp, J., Losada de la Lastra, A., Tavares, M., Volarić, J., Soudy, C., Storck, E. M., Houghton, J. W., Palma-Duran, S. A., MacRae, J. I., Tomić, G., Carr, L., Downward, J., Eggert, U. S. & Tate, E. W., 8 Jan 2024, (E-pub ahead of print) In: Nature Biotechnology.Research output: Contribution to journal › Article › peer-review
Open Access8 Citations (Scopus) -
Bronchoconstriction damages airway epithelia by crowding-induced excess cell extrusion
Bagley, D., Russell, T., Ortiz-Zapater, E., Stinson, S., Fox, K., Redd, P., Joseph, M., Deering-Rice, C., Reilly, C., Parsons, M., Brightling, C. & Rosenblatt, J., 4 Apr 2024, In: Science. 384, 6691, p. 66-73 8 p., 6691.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)69 Downloads (Pure) -
Cell adhesion and migration in disease: translational and therapeutic opportunities
Anderson, K., Calle-Patino, Y., Ivetic, A., Parsons, M., Valderrama, F., Wells, C. & Anton, I., 2024, In: Cell Adhesion and Migration. 18, 1, p. 1-3 3 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)11 Downloads (Pure) -
Cellular Imaging and Time-Domain FLIM Studies of Meso-Tetraphenylporphine Disulfonate as a Photosensitising Agent in 2D and 3D Models
Balukova, A., Bokea, K., Barber, P. R., Ameer-Beg, S. M., MacRobert, A. J. & Yaghini, E., 11 Apr 2024, In: International Journal of Molecular Sciences. 25, 8, 4222.Research output: Contribution to journal › Article › peer-review
Open Access -
Characterisation and correction of polarisation effects in fluorescently labelled fibres
Aggarwal, N., Marsh, R., Marcotti, S., Shaw, T., Stramer, B., Cox, S. & Culley, S., 29 Apr 2024, In: Journal of Microscopy.Research output: Contribution to journal › Article › peer-review
Open Access -
Derivation and simulation of a computational model of active cell populations: How overlap avoidance, deformability, cell-cell junctions and cytoskeletal forces affect alignment
Leech, V., Kenny, F., Marcotti, S., Shaw, T., Stramer, B. & Manhart, A., 29 Jul 2024, In: PLoS Computational Biology. 20, 7 JULY, e1011879.Research output: Contribution to journal › Article › peer-review
Open Access -
Development of a specific and potent IGF2BP1 inhibitor: A promising therapeutic agent for IGF2BP1-expressing cancers
Singh, A., Singh, V., Wallis, N., Abis, G., Oberman, F., Wood, T., Dhamdhere, M., Gershon, T., Ramos, A., K. Yisraeli, J., S. Spiegelman, V. & K. Sharma, A., 5 Jan 2024, In: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 263, 115940.Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus) -
DrugSynthMC: An Atom-Based Generation of Drug-like Molecules with Monte Carlo Search
Roucairol, M., Georgiou, A., Cazenave, T., Prischi, F. & Pardo, O. E., 9 Sept 2024, (E-pub ahead of print) In: JOURNAL OF CHEMICAL INFORMATION AND MODELING.Research output: Contribution to journal › Article › peer-review
Open Access -
Energy Landscapes and Structural Ensembles of Glucagon-like Peptide-1 Monomers
Keith, A. D., Brichtová, E. P., Barber, J. G., Wales, D. J., Jackson, S. E. & Röder, K., 13 Jun 2024, In: The journal of physical chemistry. B. 128, 23, p. 5601-5611 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Excitatory and inhibitory synapses show a tight subcellular correlation that weakens over development
Horton, S., Mastrolia, V., Jackson, R. E., Kemlo, S., Pereira Machado, P. M., Carbajal, M. A., Hindges, R., Fleck, R. A., Aguiar, P., Neves, G. & Burrone, J., 23 Jul 2024, In: Cell Reports. 43, 7, 114361.Research output: Contribution to journal › Article › peer-review
Open Access -
FRET Sensor-Modified Synthetic Hydrogels for Real-Time Monitoring of Cell-Derived Matrix Metalloproteinase Activity using Fluorescence Lifetime Imaging
Yan, Z., Kavanagh, T., da Silva Harrabi, R., Lust, S., Tang, C., Beavil, R., Mueller, M. M., Beavil, A., Ameer-Beg, S., M. P. da Silva, R. & Gentleman, E., 22 May 2024, In: Advanced Functional Materials. 34, 21, 2309711.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)35 Downloads (Pure) -
Injectable PEG Hydrogels with Tissue‐Like Viscoelasticity Formed through Reversible Alendronate–Calcium Phosphate Crosslinking for Cell–Material Interactions
Yu, H., Yan, Z., Dreiss, C. A., Gaitano, G. G., Jarvis, J. A., Gentleman, E., Da silva, R. M. P. & Grigoriadis, A. E., 1 Sept 2024, In: Advanced Healthcare Materials. 13, 22, 2400472.Research output: Contribution to journal › Article › peer-review
Open Access -
Integrating Porous Silicon Nanoneedles within Medical Devices for Nucleic Acid Nanoinjection
Wang, C., Gu, C., Popp, C., Vashisth, P., Mustfa, S. A., Martella, D. A., Spiteri, C., McLennan, S., Sun, N., Riddle, M., Eide, C. R., Parsons, M., Tolar, J., McGrath, J. A. & Chiappini, C., 11 Jun 2024, In: ACS Nano. 18, 23, p. 14938-14953 16 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Investigating the role connective tissue fibroblasts play in the altered muscle anatomy associated with the limb abnormality, Radial Dysplasia
Murphy, G. R. F., Feneck, E., Paget, J., Sivakumar, B., Smith, G. & Logan, M. P. O., Aug 2024, In: Journal of Anatomy. 245, 2, p. 217-230 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Muscle fibre size and myonuclear positioning in trained and aged humans
Battey, E., Levy, Y., Pollock, R., Pugh, J., Close, G. L., Kalakoutis, M., Lazarus, N. R., Harridge, S., Ochala, J. & Stroud, M., 5 Feb 2024, (Accepted/In press) In: Experimental Physiology.Research output: Contribution to journal › Article › peer-review
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N4BP1 functions as a dimerization-dependent linear ubiquitin reader which regulates TNF signalling
Kliza, K. W., Song, W., Pinzuti, I., Schaubeck, S., Kunzelmann, S., Kuntin, D., Fornili, A., Pandini, A., Hofmann, K., Garnett, J. A., Stieglitz, B. & Husnjak, K., 20 Apr 2024, In: Cell Death Discovery. 10, 1, 183.Research output: Contribution to journal › Article › peer-review
Open Access -
Nesprin-2 is a novel scaffold protein for telethonin and FHL-2 in the cardiomyocyte sarcomere
Li, C., Warren, D. T., Zhou, C., De Silva, S., Wilson, D., Garcia Maya, M., Wheeler, M., Meinke, P., Sawyer, G., Ehler, E., Wehnert, M., Rao, L., Zhang, Q. & Shanahan, C., May 2024, In: Journal of Biological Chemistry. 300, 5, 107254.Research output: Contribution to journal › Article › peer-review
Open Access -
Schizosaccharomyces versatilis represents a distinct evolutionary lineage of fission yeast
Etherington, G. J., Gil, E. G., Haerty, W., Oliferenko, S. & Nieduszynski, C. A., Mar 2024, In: Yeast. 41, 3, p. 95-107 13 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Single-molecule magnetic tweezers to probe the equilibrium dynamics of individual proteins at physiologically relevant forces and timescales
Tapia Rojo, R., Mora Hortal, M. & Garcia-Manyes, S., 11 Mar 2024, In: Nature Protocols. 19, 6, p. 1779–1806 28 p., 19.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Slac2-b Coordinates Extracellular Vesicle Secretion to Regulate Keratinocyte Adhesion and Migration
Bare, Y., Chan, G. K., Hayday, T., McGrath, J. A. & Parsons, M., 30 Sept 2024, In: Journal of Investigative Dermatology. 141, 3, p. 523-532.e2Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)173 Downloads (Pure) -
Sox9 Accelerates Vascular Aging by Regulating Extracellular Matrix Composition and Stiffness
Faleeva, M., Ahmad, S., Theofilatos, K., Lynham, S., Watson, G., Whitehead, M., Marhuenda, E., Iskratsch, T., Cox, S. & Shanahan, C. M., 2 Feb 2024, In: Circulation Research. 134, 3, p. 307-324 18 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Citations (Scopus) -
Structural anisotropy results in mechano-directional transport of proteins across nuclear pores
Panagaki, F., Tapia-Rojo, R., Zhu, T., Milmoe, N., Paracuellos, P., Board, S., Mora, M., Walker, J., Rostkova, E., Stannard, A., Infante, E. & Garcia-Manyes, S., 13 May 2024, In: Nature Physics. 20, 7, p. 1180-1193 14 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Synthesis and Biophysical Characterization of Fingolimod Derivatives as Cardiac Troponin Antagonists
Kondacs, L., Parijat, P., Cobb, A. J. A. & Kampourakis, T., 14 Mar 2024, In: Acs Medicinal Chemistry Letters. 15, 3, p. 413-417 5 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Telomere-to-telomere Schizosaccharomyces japonicus genome assembly reveals hitherto unknown genome features
Etherington, G. J., Wu, P. S., Oliferenko, S., Uhlmann, F. & Nieduszynski, C. A., Mar 2024, In: Yeast. 41, 3, p. 73-86 14 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
The Legionella collagen-like protein employs a distinct binding mechanism for the recognition of host glycosaminoglycans
Rehman, S., Antonovic, A. K., McIntire, I. E., Zheng, H., Cleaver, L., Baczynska, M., Adams, C. O., Portlock, T., Richardson, K., Shaw, R., Oregioni, A., Mastroianni, G., Whittaker, S. B. M., Kelly, G., Lorenz, C. D., Fornili, A., Cianciotto, N. P. & Garnett, J. A., Dec 2024, In: Nat Commun. 15, 1, 4912.Research output: Contribution to journal › Article › peer-review
Open Access -
The MondoA-dependent TXNIP/GDF15 1 axis predicts oxaliplatin response in colorectal adenocarcinomas. Oxaliplatin-induced immunogenicity through the regulation of the TXNIP/GDF15 axis
Deng, J., Pan, T., Wang, D., Hong, Y., Liu, Z., Zhou, X., An, Z., Li, L., Alfano, G., Li, G., Dolcetti, L., Evans, R., Vicencio Bustamante, J., Vlckova, P., Chen, Y., Monypenny of Pitmilly, J., Araujo De Carvalho Gomes, C., Weitsman, G., Ng, K., McCarthy, C., & 11 others, 3 Jul 2024, (Accepted/In press) In: EMBO Molecular Medicine.Research output: Contribution to journal › Article › peer-review
Open Access -
The RNA binding proteins LARP4A and LARP4B promote sarcoma and carcinoma growth and metastasis
Grigoriadis, A., Conte, M. R., Coleman, J., Tattersall, L., Yianni, V., Knight, L., Yu, H., Hallett, S., Johnson, P., Caetano, A., Cosstick, C., Ridley, A. & Gartland, A., 19 Apr 2024, In: iScience. 27, 4, 109288.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Transcriptomic gene signatures measure satellite cell activity in muscular dystrophies
Engquist, E., Greco, A., Joosten, L. A., van Engelen, B. G. M., Banerji, C. & Zammit, P., 21 Jun 2024, In: iScience. 27, 6, 109947.Research output: Contribution to journal › Article › peer-review
Open Access -
2023
Activation of skeletal muscle is controlled by a dual-filament mechano-sensing mechanism
Brunello, E., Marcucci, L., Irving, M. & Fusi, L., 30 May 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 22, e2302837120.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)49 Downloads (Pure) -
Affinity-enhanced RNA-binding domains as tools to understand RNA recognition
Chaves-Arquero, B., Collins, K. M., Abis, G., Kelly, G., Christodolou, E., Taylor, I. A. & Ramos, A., 26 Jun 2023, In: Cell Reports Methods . 3, 6, 100508.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
A gene regulatory network for neural induction
Trevers, K. E., Lu, H. C., Yang, Y., Thiery, A. P., Strobl, A. C., Anderson, C., Pálinkášová, B., de Oliveira, N. M. M., de Almeida, I. M., Khan, M. A. F., Moncaut, N., Luscombe, N. M., Dale, L., Streit, A. & Stern, C. D., Mar 2023, In: eLife. 12, e73189.Research output: Contribution to journal › Article › peer-review
Open Access8 Citations (Scopus) -
Age-specific and compartment-dependent changes in mitochondrial homeostasis and cytoplasmic viscosity in mouse peripheral neurons
Sleigh, J. N., Mattedi, F., Richter, S., Annuario, E., Ng, K., Steinmark, E., Ivanova, I., Daraban, I., Joshi, P., Rhymes, E. R., Awale, S., Yahioglu, G., Mitchell, J., Suhling, K., Schiavo, G. & Vagnoni, A., 20 May 2023, (Accepted/In press) In: AGING CELL.Research output: Contribution to journal › Article › peer-review
Open AccessFile23 Downloads (Pure) -
Allosteric activation of vinculin by talin
Franz, F., Tapia Rojo, R., Winograd-Katz, S., Boujemaa-Paterski, R., li, W., Unger, T., albeck, S., aponte-santamaria, C., Garcia-Manyes, S., Medalia, O., geiger, B. & grater, F., 18 Jul 2023, In: Nature Communications. 14, 4311, 4311 .Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)46 Downloads (Pure) -
A method for reproducible high-resolution imaging of 3D cancer cell spheroids
Phillips, T., Caprettini, V., Aggarwal, N., Marcotti, S., Tetley, R., Mao, Y., Shaw, T., Chiappini, C., Parsons, M. & Cox, S., Jul 2023, In: Journal of Microscopy. 291, 1, p. 30-42 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)77 Downloads (Pure) -
AMPK is a mechano-metabolic sensor linking cell adhesion and mitochondrial dynamics to Myosin-dependent cell migration
Crosas-Molist, E., Graziani, V., Maiques, O., Pandya, P., Monger, J., Samain, R., George, S. L., Malik, S., Salise, J., Morales, V., Le Guennec, A., Atkinson, R. A., Marti, R. M., Matias-Guiu, X., Charras, G., Conte, M. R., Elosegui-Artola, A., Holt, M. & Sanz-Moreno, V., 22 May 2023, In: Nature Communications. 14, 1, p. 2740Research output: Contribution to journal › Article › peer-review
Open Access -
AMPK is a mechano-metabolic sensor linking cell adhesion and mitochondrial dynamics to Myosin-dependent cell migration
Crosas-Molist, E., Graziani, V., Maiques, O., Pandya, P., Monger, J., Samain, R., George, S. L., Malik, S., Salise, J., Morales, V., Le Guennec, A., Atkinson, R. A., Marti, R. M., Matias-Guiu, X., Charras, G., Conte, M. R., Elosegui-Artola, A., Holt, M. & Sanz-Moreno, V., Dec 2023, In: Nature Communications. 14, 1, 2740.Research output: Contribution to journal › Article › peer-review
Open Access15 Citations (Scopus) -
Antibody conjugates for targeted delivery of toll-like receptor 9 agonist to the tumor tissue
Corogeanu, D., Zaki, K., Beavil, A., Arnold, J. & Diebold, S. S., 13 Mar 2023, In: PLoS One. 18, 3 March, e0282831.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
Anti-cancer pro-inflammatory effects of an IgE antibody targeting the melanoma-associated antigen chondroitin sulfate proteoglycan 4
Chauhan, J., Grandits, M., Palhares, L. C. G. F., Mele, S., Nakamura, M., López-Abente, J., Crescioli, S., Laddach, R., Romero-Clavijo, P., Cheung, A., Stavraka, C., Chenoweth, A. M., Sow, H. S., Chiaruttini, G., Gilbert, A. E., Dodev, T., Koers, A., Pellizzari, G., Ilieva, K. M., Man, F., & 20 others, 25 Apr 2023, In: Nature Communications. 14, 1, p. 2192Research output: Contribution to journal › Article › peer-review
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Anti-cancer Pro-inflammatory Effects of an IgE Antibody Targeting the Melanoma-associated Antigen Chondroitin Sulfate Proteoglycan 4
Chauhan, J., Grandits, M., Gusmao Ferreira, L. C., Mele, S., Nakamura, M., Lopez-Abente Muroz, J., Crescioli, S., Laddach, R., Romero Clavijo, P., Cheung, A., Stavraka, C., Chenoweth, A., Sow, H. S., Chiaruttini, G., Gilbert, A., Dodev, T., Koers, A., Pellizzari, G., Ilieva, K., Man, F., & 20 others, 25 Apr 2023, In: Nature Communications. 14, 1, 2192.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)113 Downloads (Pure) -
Autocrine IL-6 drives cell and extracellular matrix anisotropy in scar fibroblasts
Kenny, F., Marcotti, S., Belo De Freitas, D., Drudi, E., Leech, V., Bell, R., Easton, J., Díaz-de-la-Loza, M-C., Fleck, R., Allison, L., Philippeos, C., Manhart, A., Shaw, T. & Stramer, B., Nov 2023, In: Matrix Biology. 123, p. 1-16 16 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Citations (Scopus) -
B7-H3 associates with IMPDH2 and regulates cancer cell survival
Alhamad, S., Elmasry, Y., Uwagboe, I., Chekmeneva, E., Sands, C., Cooper, B. W., Camuzeaux, S., Salam, A. & Parsons, M., 7 Jul 2023, In: Cancers. 15, 13, 3530.Research output: Contribution to journal › Article › peer-review
Open Access -
B cell profiles, antibody repertoire and reactivity reveal dysregulated responses with autoimmune features in melanoma
Crescioli, S., Correa, I., Ng, J., Willsmore, Z. N., Laddach, R., Chenoweth, A., Chauhan, J., Di Meo, A., Stewart, A., Kalliolia, E., Alberts, E., Adams, R., Harris, R. J., Mele, S., Pellizzari, G., Black, A. B. M., Bax, H. J., Cheung, A., Nakamura, M., Hoffmann, R. M., & 23 others, 8 Jun 2023, In: Nature Communications. 14, 1, 3378.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
Bridging Imaging Users to Imaging Analysis - A community survey
Sivagurunathan, S., Marcotti, S., Nelson, C. J., Jones, M. L., Barry, D. J., Slater, T. J. A., Eliceiri, K. W. & Cimini, B. A., 5 Jun 2023, In: bioRxiv.Research output: Contribution to journal › Article
Open Access -
Bridging imaging users to imaging analysis – A community survey
Sivagurunathan, S., Marcotti, S., Nelson, C. J., Jones, M. L., Barry, D. J., Slater, T. J. A., Eliceiri, K. W. & Cimini, B. A., 13 Sept 2023, In: Journal of Microscopy.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
CD73 controls Myosin II–driven invasion, metastasis, and immunosuppression in amoeboid pancreatic cancer cells
Samain, R., Maiques, O., Monger, J., Lam, H., Candido, J., George, S., Ferrari, N., Kohihammer, L., Lunetto, S., Varela, A., Orgaz, J. L., Vilardell, F., Olsina, J. J., Matias-Guiu, X., Sarker, D., Biddle, A., Balkwill, F. R., Eyles, J., Wilkinson, R. W., Kocher, H. M., & 3 others, 2023, In: Science Advances. 9, 42, adi0244.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
Cell-cell metabolite exchange creates a pro-survival metabolic environment that extends lifespan
Correia-Melo, C., Kamrad, S., Tengölics, R., Messner, C. B., Trebulle, P., Townsend, S. J., Jayasree Varma, S., Freiwald, A., Heineike, B. M., Campbell, K., Herrera-Dominguez, L., Kaur Aulakh, S., Szyrwiel, L., Yu, J. S. L., Zelezniak, A., Demichev, V., Mülleder, M., Papp, B., Alam, M. T. & Ralser, M., 5 Jan 2023, In: Cell. 186, 1, p. 63-79.e21Research output: Contribution to journal › Article › peer-review
Open Access19 Citations (Scopus) -
Comorbidities of Keloid and Hypertrophic Scars Among Participants in UK Biobank: Comorbidities of excessive scarring
Ung, C. Y., Warwick, A. N., Onoufriadis, A., Barker, J., Parsons, M., McGrath, J., Shaw, T. & Dand, N., 4 Jan 2023, In: JAMA dermatology. 159, 2, p. 172-181 10 p.Research output: Contribution to journal › Article › peer-review
15 Citations (Scopus)