Randall Centre of Cell & Molecular Biophysics

Research output

Research output per year 1974 2001 2002 2003 2004 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024

• 336341 Citations
• 2510 Article
• 157 Meeting abstract
• 97 Review article
• 87 Literature review
• 276 More
  • 69 Chapter
  • 64 Conference paper
  • 49 Editorial
  • 24 Comment/debate
  • 20 Letter
  • 13 Book
  • 9 Preprint
  • 8 Short survey
  • 6 Meeting Abstract
  • 5 Poster abstract
  • 2 Other contribution
  • 2 Patent
  • 1 Report
  • 1 Conference contribution
  • 1 Foreword/postscript
  • 1 Other chapter contribution
  • 1 Abstract

Research output per year

Research output per year

Search results

• 2021

  Dynamics of Structural Changes in Myosin-Containing Filaments of Intact Mouse EDL During Twitch and Tetanic Contractions

  Hill, C., Brunello, E., Fusi, L., Garcia Ovejero, J. & Irving, M., 12 Feb 2021, In: Biophysical Journal. 120, 3, 61A.

  Research output: Contribution to journal › Meeting abstract › peer-review

  Open Access

  • Myosin 100%
  • Mouse 100%
  • Actin 33%
  • Ray 22%
  • X Ray 22%
• 2018

  OP-6 - The human Golgi anti-apoptotic protein induces cell invasion by an H2O2-dependent mechanism

  Almeida, N., Carrara, G., Fernandes, A., Parsons, M., Smith, G. & Saraiva, N., 20 May 2018, In: Free Radical Biology and Medicine. 120, Supplement 1, p. S31

  Research output: Contribution to journal › Meeting abstract › peer-review

  • Protein 100%
  • Cell Migration 12%
  • Reduction (Chemistry) 12%
  • Protein Catabolism 12%
  • Housekeeping Gene 12%

• P-240 - Beneficial impact of a manganese(III) porphyrin in cancer cell migration

  Saraiva, N., Flóridol, A., Costa, J., Parsons, M., Batinic-Haberle, I., Miranda, J. P., Castro, M., Oliveira, N. G. & Fernandes, A. S., 20 May 2018, In: Free Radical Biology and Medicine. 120, Supplement 1, p. S117-S118

  Research output: Contribution to journal › Meeting abstract › peer-review

  • Cell Migration 100%
  • Manganese 100%
  • Cancer Cell 100%
  • Anticancer 50%
  • Clinical Trial 25%

• RNAseq reveals mechanisms of cardiomyopathy in Mlp-C58G knock-in mice: SI:Abstracts ISHR-ES Amsterdam

  Ehsan, M., Kelly, M., Hooper, C., Beglov, J., Davies, B., Fleischanderld, K., Ehler, E., Redwood, C., Watkins, H. & Gehmlich, K., 2018, In: Journal of Molecular and Cellular Cardiology. 120

  Research output: Contribution to journal › Meeting abstract

  • Protein 100%
  • Myocardial Disease 100%
  • Hypertrophic Cardiomyopathy 83%
  • Gene 66%
  • Congestive Heart Failure 33%
• 2017

  P.480 - Establishment of an international database of Titin mutations and their phenotypes – a follow up: 22nd International Congress of the World Muscle Society

  Hackman, P., Savarese, M., Bönneman, C., Ferreiro, A., Beggs, A., Gautel, M., Davis, M., Evangelista, T., Glumac, J. N., Laporte, J., Smith, J., Richard, I., Granzier, H., Schneider, R., Jungbluth, H., Foye, S., Frase, A. R. & Udd, B., 12 Sept 2017, (E-pub ahead of print) In: Neuromuscular Disorders. 27, Supplement 2, p. S239-S240

  Research output: Contribution to journal › Meeting abstract › peer-review
  11 Citations (Scopus)
• 2016

  Stress-Sensing Mobilizes Myosin Motors in the Thick Filaments of Resting Muscle

  Reconditi, M., Brunello, E., Caremani, M., Fusi, L., Linari, M., Narayanan, T., Piazzesi, G., Irving, M. & Lombardi, V., 16 Feb 2016, In: Biophysical Journal. 110, 3, Supplement 1, p. 13a

  Research output: Contribution to journal › Meeting abstract

• Structure and Function of the Levosimendan Analog I9 Covalently Bound to Cardiac Troponin C

  Elizabeth Pineda-Sanabria, S., Robertson, I. M., Sun, Y-B., Irving, M. & Sykes, B. D., 16 Feb 2016, In: Biophysical Journal. 110, 3, Supplement 1, p. 123a

  Research output: Contribution to journal › Meeting abstract
• 2014

  Engineered IgE antibodies recognising tumour associated antigens: a paradigm for activating immune effector functions against cancer

  Karagiannis, S. N., Josephs, D. H., Bax, H., Karagiannis, P., Saul, L., Dodev, T., Blower, P., Beavil, A., Gould, H. & Spicer, J., Nov 2014, International Journal of Molecular Medicine. Supplement 1 ed. Athens, Greece: SPANDIDOS PUBL LTD, POB 18179, ATHENS, 116 10, GREECE, Vol. 34. p. S86-S86 425

  Research output: Chapter in Book/Report/Conference proceeding › Meeting abstract
• 2013

  Detection and quantitation of total and allergen specific IgE in the bronchial mucosa of atopic and non-atopic asthmatics

  Pillai, P., Fang, C., Chan, C., Shamji, M., Harper, C., Ohm-Laursen, L., Durham, S., Menzies-Gow, A., Rajakulasingam, R., Sun, Y., Corrigan, C. & Gould, H., Dec 2013, In: Clinical and Experimental Allergy. 43, 12, p. 1441-1441 1 p., P.20.

  Research output: Contribution to journal › Meeting abstract › peer-review

  Open Access

  • Immunoglobulin E 100%
  • Homogenate 50%
  • Serum (Blood) 10%

• Immunotherapy of solid tumors with IgE antibodies: Paradigm of a novel concept towards clinical application

  Karagiannis, S. N., Josephs, D. H., Karagiannis, P., Saul, L., Gilbert, A. E., Dodev, T., Koers, A., Blower, P. J., Beavil, A. J. & Nestle, F. O., 2013, In: Cancer Research. 73, 1 Supplement, p. B46-B46

  Research output: Contribution to journal › Meeting abstract › peer-review

• Novel Labeling Schemes for Single-Molecule Localization Microscopy

  Ries, J., Schoen, I., Platonova, E., Kaplan, C. & Ewers, H., 29 Jan 2013, In: Biophysical Journal. 104, 2, p. 8A-9A 2 p.

  Research output: Contribution to journal › Meeting abstract › peer-review
• 2012

  A novel complement-mediated pathway for human T(H)2 induction via direct epithelial cell/T cell crosstalk

  Fara, A. F., Yamamoto, H., Morton, P., Parsons, M., Koehl, J. & Kemper, C., Nov 2012, In: Immunobiology. 217, 11, p. 1219-1220 2 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

  • Lung 100%
  • Toll-Like Receptor 50%
  • T-Helper Cell 24%
  • Mouse Model 24%
  • Molecule 24%

• A Simple, Versatile Method for GFP-Based Single Molecule Localization Microscopy

  Ries, J., Kaplan, C., Platonova, E., Eghlidi, H. M. & Ewers, H., 31 Jan 2012, In: Biophysical Journal. 102, p. 419A-419A 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Discovering antibodies for immunotherapy of solid tumours: from the lab bench toward; clinical application

  Karagiannis, S., Josephs, D. H., Karagiannis, P., Sau, L., Gilbert, A. E., Dodev, T., Koers, A., Blower, P. J., Beavil, A. J., Spicer, J. F., Nestle, F. O. & Gould, H. J., 2012, In: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 30, p. S11-S11 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Identification of Jagged1 as a novel ligand for CD46: An interaction required for normal induction and regulation of human TH1 responses

  Le Friec, G., Sheppard, D., Karsten, C. M., Whiteman, P., Shamoun, S., Laing, A., Waddington, S. N., McDonnell, J. M., Fremeaux-Bacchi, V., Couzi, L., Koehl, J., Baker, A., Handford, P. A., Lea, S. M. & Kemper, C., Nov 2012, In: Immunobiology. 217, 11, p. 1176-1176 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

  • Notch 100%
  • T-Helper Cell 66%
  • Complement Regulator 33%
  • Common Variable Immunodeficiency 33%
  • Graft-Versus-Host Disease 33%

• IgE antibodies targeting a major melanoma antigen are more effective than IgG antibodies for tumour protection in a humanized melanoma model

  Karagiannis, P., Gilbert, A. E., Dodev, T., Josephs, D. H., Ali, N., Dafou, D., Ainali, C., Koers, A., Saul, L., Tsoka, S., Spicer, J., Gould, H. J., Beavil, A., Nestle, F. O. & Karagiannis, S. N., Apr 2012, In: British Journal of Dermatology. 166, 4, p. e20 1 p., o-14.

  Research output: Contribution to journal › Meeting abstract › peer-review
  14 Citations (Scopus)

• Novel regulation of cardiac protein kinase D1 activation and histone deacetylase phosphorylation by four-and-a-half LIM-only (FHL) proteins

  Stathopoulou, K., Cuello, F., Ehler, E., Haworth, R. S. & Avkiran, M., 2012, In: Cardiovascular Research. 93, p. S59 - S60

  Research output: Contribution to journal › Meeting abstract

• Phosphoregulation of the titin-cap protein telethonin in cardiac myocytes

  Candasamy, A. J., Haworth, R. S., Boguslavsky, A., Cuello, F., Shattock, M. J., Mayr, M., Gautel, M. & Avkiran, M., 2012, In: Cardiovascular Research. 93, S1, p. S17 - S17

  Research output: Contribution to journal › Meeting abstract

• Reduced tumor load and metastasis in vivo by targeting a metalloprotease-disintegrin, ADAM8, in highly invasive adenocarcinomas

  Schlomann, U., Ferdous, T., Golfi, P., Koller, G., Parsons, M., Hoefling, S., Hagemann, T., Bossard, M., Nimsky, C. & Bartsch, J. W., Apr 2012, In: Faseb Journal. 26, p. - 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Role of Ret in satellite cell myogenesis and facioscapulohumeral muscular dystrophy

  Moyle, L., Knight, R., Knopp, P. & Zammit, P., 2012, In: Neuromuscular Disorders. 22, p. S15 - S15

  Research output: Contribution to journal › Meeting abstract

• Targeted deletion of Dicer alters the cardiac mitochondrial and myofilament subproteome

  Abonnenc, M., Martins, P. D. C., Srivastava, S., Didangelos, A., Yin, X., Gautel, M., De Windt, L. & Mayr, M., 2012, In: Cardiovascular Research. 93, p. S81 - S81

  Research output: Contribution to journal › Meeting abstract

• The intercalated disc - a truly special type of cell-cell contact in dilated cardiomyopathy

  Hirschy, A. & Ehler, E., May 2012, In: Cell and Tissue Research. 348, 2, p. 340-341 2 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• The novel Jagged/1CD46 interaction: a prime target for immune modulation by viruses?

  Lea, S. M., Sheppard, D., Whiteman, P., le Friec, G., Waddington, S. N., Smith, R., Melchionna, T., Kemper, C., McDonnell, J., Handford, P. A. & McDonnell, J., Sept 2012, In: Immunology. 137, p. 7-8 2 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• The novel Jagged1/CD46 interaction: A prime target for immune modulation by viruses?

  Sheppard, D., Whiteman, P., Le Friec, G., Waddington, S. N., Smith, R., Melchionna, T., Kemper, C., McDonnell, J. M., Handford, P. A. & Lea, S. M., Nov 2012, In: Immunobiology. 217, 11, p. 1210-1211 2 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

  • C3b 100%
  • Measles 66%
  • Complement Regulator 33%
  • Viral Disease 33%
  • Surface Plasmon Resonance 33%

• The transcription factor Erg regulates expression of HDAC6 and multiple pathways involved in endothelial cell migration and angiogenesis

  Birdsey, G. M., Dryden, N. H., Shah, A. V., Hannah, R., Parsons, M., Mason, J. C., Zvelebil, M., Gottgens, B., Ridley, A. J. & Randi, A. M., 2012, In: VASCULAR PHARMACOLOGY. 56, 5-6, p. 348-349 2 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

  • Cell Migration 100%
  • HDAC6 100%
  • Tubulin 57%
  • Acetylation 42%
  • Gene 28%
• 2011

  Application of a new strategy to identify regulators of a signalling pathway in human immune cells

  Milewicz, H., Carlin, L., Fernandes, L., Matthews, D. R., Perani, M., Levitt, J., Keppler, M. D., Coolen, T., Barber, P. R., Vojnovic, B., Suhling, K., Fraternali, F., Ameer-Beg, S., Parker, P. J., Thomas, N. S. B. & Ng, T., 2011, In: British Journal of Haematology. 153, p. 19 - 19 1 p.

  Research output: Contribution to journal › Meeting abstract

• Chemical approach to understanding cell division

  Eggert, U., 27 Mar 2011, In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 241, p. - 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Co-regulation of mutual target genes by Ntla and Tbx16 in zebrafish mesoderm development

  Jahangiri, L. & Wardle, F., 2011, In: Developmental Biology. 356, 1, p. 261 - 261 1 p.

  Research output: Contribution to journal › Meeting abstract

• Cortical clustering of cell polarity regulators.

  Dodgson, J., Chessel, A., Vaggi, F., Cox, S., Rosten, E., Yamamoto, M., Geymonat, M., Dong, Y., Ahringer, J., Albrecht, D., Sato, M., Csikasz-Nagy, A. & Salas, R. C., 2011, In: Molecular Biology of the Cell. 22, p. - 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Dominant Vinculin Binding Angle in Podosomes Revealed by High Resolution Optical Microscopy

  Cox, S., Walde, M., Monypenny, J., Heintzmann, R. & Jones, G. E., 2 Feb 2011, In: Biophysical Journal. 100, 3, p. 616-616 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• ErbB3 binding protein-1 (Ebp1) contributes to the control of proliferation and differentiation in adult muscle satellite cells

  Figeac, N. & Zammit, P. S., 2011, In: Neuromuscular Disorders. 21, p. S12 - S12

  Research output: Contribution to journal › Meeting abstract

• Establishing the role of BPAG1-e in hemidesmosomal integrity and keratinocyte cell biology

  Michael, M., Fong, K., Lai-Cheong, J. E., Dopping-Hepenstal, P. J., Liu, L., Groves, R. W., Mellerio, J. E., Parsons, M. & McGrath, J. A., 2011, In: British Journal of Dermatology. 164, 4, p. 913 - 913 1 p.

  Research output: Contribution to journal › Meeting abstract

• Generation of a high affinity Phl p 7-specific IgG4 antibody

  James, L., Bowen, H., Goldstone, A., Durham, S. R. & Gould, H., Dec 2011, In: Clinical and Experimental Allergy. 41, 12, p. 1832-1832 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• IgE immunotherapy of solid tumours: a novel model targeting folate receptor alpha (FR alpha)-positive carcinomas with MOv18 IgE

  Josephs, D., Rudman, S., Karagiannis, P., Gilbert, A. E., Gould, H. J., Nestle, F. O., Spicer, J. & Karagiannis, S., 2011, In: British Journal of Dermatology. 164, 4, p. 909 - 910 2 p.

  Research output: Contribution to journal › Meeting abstract

• Investigating anti-HMW-MAA IgG and anti-HMW-MAA IgE antibodies: a new approach in immunotherapy of melanoma

  Karagiannis, P., Gilbert, A. E., Dodev, T., Josephs, D. H., Koers, A., Ali, N., Gould, H. J., Nestle, F. O. & Karagiannis, S. N., 2011, In: British Journal of Dermatology. 164, 4, p. 922-922 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Multimodal imaging of drug delivery using liposomes functionalised with MRI, PET and SPECT contrast agents to target sites of pathological interest

  Mitchell, N., Kalber, T., Cooper, M., Cheung, A., Fruhwirth, G., Blower, P., Ng, T., Lythgoe, M., Hailes, H. C. & Tabor, A. B., 2011, In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 242

  Research output: Contribution to journal › Meeting abstract

• Onset of pro-invasive squamous cell carcinoma microenvironment is associated with ROCK and JAK1 signaling which controls acto-myosin contractility in stroma fibroblasts

  Gaggioli, C., Sanz Moreno, V., Albrengues, J., Marshall, C. & Meneguzzi, G., Sept 2011, In: Journal of Investigative Dermatology. 131, p. S21-S21 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Reduced expression of several actin-associated focal adhesion proteins in Kindler syndrome keratinocytes harbouring FERMT1 mutations

  Begum, R., Lai-Cheong, J. E., Parsons, M. & McGrath, J. A., 2011, In: British Journal of Dermatology. 164, 4, p. 927 - 928 2 p.

  Research output: Contribution to journal › Meeting abstract

• Resistin-like Molecule-beta (relm-beta) Influences Airways Epithelial Remodelling By Inducing Mucin And Transforming Growth Factor-beta 2 Gene Expression

  Fang, C., Meng, Q., Wu, H. F., Zhang, G. Z., Zhang, X. W., Song, Y., Lee, T. H., Corrigan, C. J. & Ying, S., Feb 2011, In: Journal of Allergy and Clinical Immunology. 127, 2, p. AB269-AB269 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• SHARPIN is an endogenous inhibitor of beta1-integrin activation

  Rantala, J., Pouwels, J., Pellinen, T., Veltel, S., Laasola, P., Potter, C., Duffy, T., Sundberg, J., Kallioniemi, O., Askari, J., Humphries, M., Parsons, M., Salmi, M. & Ivaska, J., 2011, In: Molecular Biology of the Cell. 22, p. - 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• The host muscle environment has got a profound effect on satellite cell function

  Boldrin, L., Zammit, P. S., Muntoni, F. & Morgan, J. E., 2011, In: Neuromuscular Disorders. 21, p. S12 - S12

  Research output: Contribution to journal › Meeting abstract
• 2010

  Characterization of antibody responses in malignant melanoma

  Karagiannis, P., Beddowes, E., Gilbert, A. E., Abu-Nab, Z., Fear, D., Gould, H. J., Lacy, K., Nestle, F. O. & Karagiannis, S., 2010, In: British Journal of Dermatology. 162, 4, p. 935 - 935 1 p.

  Research output: Contribution to journal › Meeting abstract

• Dynamics of sub-synaptic vesicles and surface microclusters at the T cell immunological synapse

  Purbhoo, M. A., Liu, H., Oddos, S., Owen, D., Neil, M. A. A., Pageon, S. V., French, P. M. W., Rudd, C. E. & Davis, D. M., Dec 2010, In: Immunology. 131, p. 175-175 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• FUNCTIONAL IMAGING: PROTEIN AND PROTEIN INTERACTIONS AS A POTENTIAL COMPANION OF DIAGNOSTIC TOOLS

  Ng, T., Kelleher, M. T., Patel, G., Lawler, K. & Coolen, A., 2010, In: Annals of Oncology. 21, p. 23 - 23 1 p.

  Research output: Contribution to journal › Meeting abstract

  2499 Citations (Scopus)

• Hoxa9 Suppresses Cellular Senescence and Sustains the Development of Leukemic Stem Cells Induced by Fusion Proteins In the Absence of Bmi1

  Smith, L. L., Yeung, J., Zeisig, B. B., Huijbers, I., Popov, N., Barnes, J., Wilson, A. J., Lugthart, S., Delwel, R., Gil, J., van Lohuizen, M. & So, C. W. E., 2010, In: Blood. 116, 21, p. 667 - 667 1 p.

  Research output: Contribution to journal › Meeting abstract

• IgE immunotherapy of solid tumours: a novel model targeting folate receptor alpha-positive carcinomas with MOv18 IgE

  Josephs, D., Rudman, S., Karagiannis, P., Cambrook, H., Gilbert, A. E., Gould, H. J., Nestle, F. O., Spicer, J. & Karagiannis, S., 2010, In: British Journal of Dermatology. 162, 4, p. 946 - 947 2 p.

  Research output: Contribution to journal › Meeting abstract

• In vitro characterisation of an imaging ligand for detection of C3d deposition in vivo

  Badar, A., De Freitas, S., Yahya, M. N., McDonnell, J. M., Thakor, D., Smith, R. A. G., Sacks, S. H. & Mullen, G. E. D., 2010, In: Molecular Immunology. 47, 13, p. 2204 - 2204 1 p.

  Research output: Contribution to journal › Meeting abstract

• Mice lacking lamin A/C have disorganised myotendinous junctions and perturbed satellite cell function

  Gnocchi, V., Scharner, J., Sun, Y. -B., Ellis, J. & Zammit, P., 2010, In: Neuromuscular Disorders. 20, p. S15 - S15

  Research output: Contribution to journal › Meeting abstract

• Nasal RAG1-and RAG2-Expressing Cells May Suggest the Nose As A Tertiary Lymphoid Organ

  Nouri-Aria, K. T., Wu, H., Gevaert, P., Takhar, P., Bachert, C., Durham, S. R. & Gould, H. J., 2010, In: Journal of Allergy and Clinical Immunology. 125, 2, p. AB204 - AB204

  Research output: Contribution to journal › Meeting abstract

• New regulators of the BRCA1 response to genotoxic stress

  Morris, J. R., Boutell, C., Keppler, M., Densham, R., Weekes, D., Alamshah, A., Butler, L., Galanty, Y., Pangon, L., Kiuchi, T., Ng, T. & Solomon, E., 2010, In: Breast Cancer Research. 12, p. S2 - S2 O3.

  Research output: Contribution to journal › Meeting abstract