SCMMS Southbank

Projects

Projects per year 2020 2021 2022 2023 2024 2032

• 24 Finished
• 46 Active

Projects per year

Search results

• Active

  Developing a Personalized Drug Screening Platform for Diabetic Microangiopathy

  Zampetaki, A. (Primary Investigator), Giacca, M. (Co-Investigator), Jackson, T. (Co-Investigator), Modarai, B. (Co-Investigator) & Theofilatos, K. (Co-Investigator)

  DIABETES UK

  1/05/2025 → 30/04/2028

  Project: Research

• Family study of early hypertension in children and young people at risk of autosomal dominant polycystic kidney disease

  academic, A. (Primary Investigator), Chowienczyk, P. (Co-Investigator) & Pushparajah, K. (Co-Investigator)

  KIDNEY RESEARCH UK

  1/04/2025 → 31/03/2028

  Project: Research

• The effects of implanting aortic stent grafts on aortic stiffness and cardiac function

  Abdelhalim, M. (Primary Investigator)

  Academy of Medical Sciences

  18/03/2025 → 17/03/2027

  Project: Research

• Arterial stiffening and hypertension in children and young adults

  academic, A. (Primary Investigator), Chowienczyk, P. (Co-Investigator) & Pushparajah, K. (Co-Investigator)

  BHF British Heart Foundation

  1/02/2025 → 31/10/2028

  Project: Research

• The pro-angio/arteriogenic monocyte: A key prognostic indicator and therapeutic target in patients with limb ischaemia

  Modarai, B. (Primary Investigator) & Douiri, A. (Co-Investigator)

  BHF British Heart Foundation

  1/02/2025 → 31/01/2030

  Project: Research

• Nogo-B in the aldosterone sensitive distal nephron: novel role on Na+/water balance and blood pressure regulation.

  Gnudi, L. (Primary Investigator)

  BHF British Heart Foundation

  18/11/2024 → 17/11/2027

  Project: Research

• Elucidating the pathophysiological link between coronary microvascular dysfunction and heart failure with preserved ejection fraction

  Perera, D. (Primary Investigator), Chiribiri, A. (Co-Investigator) & Rahman, H. (Co-Investigator)

  BHF British Heart Foundation

  1/11/2024 → 31/10/2027

  Project: Research

• Deciphering Mechanisms of CDK19-induced Transcriptional Reprogramming in PH (PG/23/11522: Re-submission)

  Rudyk, O. (Primary Investigator)

  BHF British Heart Foundation

  1/10/2024 → 30/09/2027

  Project: Research

• Manipulation of the endogenous monocyte/macrophage niche using mesenchymal stem cell-derived extracellular vesicles to revascularise the ischaemic leg

  Patel, A. (Primary Investigator)

  BHF British Heart Foundation

  1/10/2024 → 30/09/2027

  Project: Research

• REvascularisation for heart failure with PReserved ejection fraction and Ischaemia: EValuation of Efficacy and mechanistic Description - REPRIEVED-Phase II Trial

  Ryan, M. (Primary Investigator), Chiribiri, A. (Co-Investigator), Perera, D. (Co-Investigator) & Sanders, J. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/09/2024 → 31/08/2029

  Project: Research

• Defining a new mechanism of blood pressure regulation and its role during sepsis

  Burgoyne, J. (Primary Investigator)

  MRC Medical Research Council

  1/06/2024 → 31/05/2027

  Project: Research

• Studying the role of XRCC4 oxidation in vascular aging

  Burgoyne, J. (Primary Investigator)

  BHF British Heart Foundation

  1/05/2024 → 31/05/2027

  Project: Research

• SHIFT-DCM - Decoding oxidative stress mechanisms in dilated cardiomyopathy: Shifting progressive impairment to cardioprotection

  Burgoyne, J. (Primary Investigator) & Giacca, M. (Co-Investigator)

  BHF British Heart Foundation

  1/05/2024 → 30/04/2028

  Project: Research

• Support for final product development and regulatory submission of an ultrasensitive point of care troponin test

  Marber, M. (Primary Investigator) & Marber, M. (Primary Investigator)

  NIHR National Institute For Health & Care Research

  1/05/2024 → 31/07/2026

  Project: Research

• The role of anti-inflammatory treatments in the prevention of post thrombotic fibrosis

  Smith, A. (Primary Investigator)

  BHF British Heart Foundation

  24/04/2024 → 23/04/2027

  Project: Research

• Importance of zinc in nitric oxide and NRF2-regulated redox signalling in human brain microvascular endothelial cells under physiological shear stress and oxygen levels

  Mann, G. (Primary Investigator), Chapple, S. (Co-Investigator) & Morrell, A. (Co-Investigator)

  BHF British Heart Foundation

  1/04/2024 → 31/03/2027

  Project: Research

• A Novel AI-derived Measure Of Early Systolic Function To Guide Management Of Heart Failure

  Gu, H. (Primary Investigator), Chowienczyk, P. (Co-Investigator), Douiri, A. (Co-Investigator), Perera, D. (Co-Investigator) & academic, A. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/04/2024 → 31/03/2029

  Project: Research

• Nrf2 targeting to improve transgenerational islet function

  Chapple, S. (Primary Investigator), Bowe, J. (Co-Investigator) & Malik, A. (Co-Investigator)

  DIABETES UK

  1/04/2024 → 31/03/2027

  Project: Research

• Patient-derived organoids under physiological oxygen: an improved pre-clinical model for hypoxia induced lung cancer metastasis

  Mann, G. (Primary Investigator)

  Royal Society

  31/03/2024 → 30/03/2026

  Project: Research

• Implementation of Comprehensive Geriatric Assessment based perioperative medicine services to improve clinical outcomes for older patients undergoing elective and emergency surgery with cost effectiveness POPS-Sup

  Byford, S. (Primary Investigator), Healey, A. (Co-Investigator) & Modarai, B. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/02/2024 → 30/04/2027

  Project: Research

• PLUTO - Effect of ethnicity on cardio-renal markers and function in type 1 diabetes Type 1 study CTIMP

  Karalliedde, J. (Primary Investigator), Ayis, S. (Co-Investigator) & Chiribiri, A. (Co-Investigator)

  Breakthrough T1D

  1/01/2024 → 31/12/2025

  Project: Research

• VITAL: VIrtual Twins as tools for personalised clinicAL care

  Alastruey, J. (Primary Investigator) & Chowienczyk, P. (Co-Investigator)

  TSB Technology Strategy Board

  1/01/2024 → 31/12/2028

  Project: Research

• Real-time modelling of spinal cord blood flow using artificial intelligence generated Digital Twins for personalised prediction and risk management of paraplegia following aortic surgery

  Modarai, B. (Primary Investigator), Cardoso, J. (Co-Investigator) & Lamata de la Orden, P. (Co-Investigator)

  BHF British Heart Foundation

  1/12/2023 → 30/11/2026

  Project: Research

• A magnetic resonance imaging strategy for accessment of oxygenation and perfusion after revascularisation of the ischaemic limb

  Modarai, B. (Primary Investigator), Botnar, R. (Co-Investigator), Chiribiri, A. (Co-Investigator), Douiri, A. (Co-Investigator), Patel, A. (Co-Investigator) & Smith, A. (Co-Investigator)

  BHF British Heart Foundation

  11/10/2023 → 10/10/2025

  Project: Research

• Midlife Aging in the Dunedin Study Phase 52

  Moffitt, T. (Primary Investigator), Aarsland, D. (Co-Investigator), Caspi, A. (Co-Investigator) & Siow, R. (Co-Investigator)

  MRC Medical Research Council

  1/10/2023 → 30/09/2028

  Project: Research

• A multicentre randomised trial of surgical versus percutaneous treatment of ischaemicheart failure in the United Kingdom, with embedded internal pilot and health economic analysis (BCIS-4)

  Perera, D. (Primary Investigator) & Ryan, M. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/10/2023 → 28/02/2032

  Project: Research

• BHF Centre Burgoyne PhD Studentship 2023

  Burgoyne, J. (Primary Investigator)

  BHF British Heart Foundation

  1/10/2023 → 30/09/2026

  Project: Research

• Novel functions of LC3: A new mechanism for targeting proteins for degradation that is dysregulated during the development of heart failure

  Burgoyne, J. (Primary Investigator)

  BHF British Heart Foundation

  1/08/2023 → 14/08/2026

  Project: Research

• Recovering locomotion after acute ischemic spinal cord injury

  Warren, P. (Primary Investigator), Bradbury, E. (Co-Investigator) & Modarai, B. (Co-Investigator)

  Brain Research UK

  1/07/2023 → 30/06/2026

  Project: Research

• Molecular mechanisms of neurovascular dysfunction in Brain Ageing

  Siow, R. (Primary Investigator)

  Stavanger University Hospital

  1/07/2023 → 30/06/2026

  Project: Research

• Optical coherence tomography with magnetic resonance angiography to assess STEMI non-culprit risk (OCT-RISK)

  Perera, D. (Primary Investigator) & Botnar, R. (Co-Investigator)

  BHF British Heart Foundation

  1/04/2023 → 31/03/2026

  Project: Research

• Improving diagnosis and outcomes of Coronary Microvascular Dysfunction by applying a network approach across the UK

  Rahman, H. (Primary Investigator)

  Academy of Medical Sciences

  6/03/2023 → 5/03/2026

  Project: Research

• Evaluation Of First-phase Ejection Fraction To Guide Cardiac Resynchronization Therapy

  Chowienczyk, P. (Primary Investigator), Gu, H. (Co-Investigator) & academic, A. (Co-Investigator)

  BHF British Heart Foundation

  3/01/2023 → 23/11/2026

  Project: Research

• Functional Outcomes In Severe Symptomatic Aortic Stenosis After Transcatheter Valve Implantation

  Redwood, S. (Primary Investigator)

  BHF British Heart Foundation

  1/11/2022 → 31/10/2025

  Project: Research

• Cardiac myosin-binding protein C (cMyC) fragmentation patterns in different types of myocardial infarction

  Marber, M. (Primary Investigator), Marber, M. (Primary Investigator) & Mayr, M. (Co-Investigator)

  BHF British Heart Foundation

  5/10/2022 → 11/11/2025

  Project: Research

• Targeting heart failure with preserved ejection fraction by polyphenol-dependent oxidation of PKG1a

  Burgoyne, J. (Primary Investigator)

  BHF British Heart Foundation

  1/10/2022 → 30/09/2025

  Project: Research

• Systo-diastolic coupling as a therapeutic target for heart failure with preserved ejection fraction

  Chowienczyk, P. (Primary Investigator), Douiri, A. (Co-Investigator) & Shah, A. (Co-Investigator)

  MRC Medical Research Council

  1/10/2022 → 30/09/2025

  Project: Research

• Understanding how sNogo-B protects blood vessels in diabetic kidney disease.

  Gnudi, L. (Primary Investigator)

  DIABETES UK

  1/09/2022 → 31/08/2026

  Project: Research

• HY CYP: Haemodynamic determinants of hYpertension in Children and Young People and role of the sympathetic nervous system: HY CYP

  Chowienczyk, P. (Primary Investigator) & Haseler, E. (Co-Investigator)

  MRC Medical Research Council

  1/09/2022 → 30/06/2026

  Project: Research

• Children of UPBEAT; a study of Cardiovascular Function in 9-10yr old children of Obese Women who Participated in an Antenatal Lifestyle Intervention

  Taylor, P. (Primary Investigator), Chowienczyk, P. (Co-Investigator), Gu, H. (Co-Investigator), Poston, L. (Co-Investigator) & Santosh, P. (Co-Investigator)

  BHF British Heart Foundation

  1/06/2022 → 31/03/2026

  Project: Research

• A multidisciplinary cross site collaboration to optimise outcomes of patients requiring advanced mechanical circulatory support: adjunctive left ventricular unloading with veno-arterial ECMO’

  Perera, D. (Primary Investigator) & academic, A. (Co-Investigator)

  KHP King's Health Partners

  1/03/2022 → 31/08/2025

  Project: Research

• The antiarrhythmic properties and mechanism of action of an ischaemia-activated prodrug of diltiazem

  Curtis, M. (Primary Investigator) & Eykyn, T. (Co-Investigator)

  BHF British Heart Foundation

  1/02/2022 → 31/07/2025

  Project: Research

• Genome-wide CRISPR Knock-out Screen to Identify Genes Essential for Senescent Cell Survival

  Burgoyne, J. (Primary Investigator)

  Norn Group

  1/01/2022 → 31/12/2027

  Project: Research

• Bp response Assessment BY Pregnancy ANtihypertensive Drug treAtment: (Mechanism of Action of Health Intervention): BABY PANDA study

  Chappell, L. (Primary Investigator), Ashworth, D. (Co-Investigator) & Webb, A. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/10/2021 → 30/09/2025

  Project: Research

• New approaches to Mitigate LV injury with VA-ECMO in AMI

  Perera, D. (Primary Investigator)

  NIH National Institutes of Health

  1/08/2021 → 31/07/2025

  Project: Research

• Controlled trial of High-risk percutaneous coronary Intervention with Percutaneous left ventricular unloading (CHIP)

  Perera, D. (Primary Investigator) & Ryan, M. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/10/2020 → 30/09/2026

  Project: Research