Wolfson Centre for Age Related Diseases

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• Ubiquitin proteasome system impairment and its relationships to cognitive and non-cognitive symptoms, pathology and synaptic dysfunction, in the Lewy body dementias.

  Author: Alghamdi, A. A., 2015

  Supervisor: Hortobagyi, T. (Supervisor) & Francis, P. T. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• TRP channel control of pain and analgesia

  Author: Semizoglou, E., 1 Aug 2021

  Supervisor: Andersson, D. (Supervisor) & Bevan, S. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• The use of AAV vectors for transgene expression in primary afferent neurons in vitro and in vivo, and their utility in investigation of primary afferent anatomy and physiology

  Author: Khovanov, N., 1 Jan 2019

  Supervisor: McMahon, S. B. (Supervisor) & Bennett, D. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The Unfolded Protein Response : A potential link between heterozygous mutations in GBA1 and Lewy body dementia?

  Author: Clarke, E. J., 2018

  Supervisor: Broadstock, M. (Supervisor) & Francis, P. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The role of retinoic acid in adult neurogenesis

  Author: Evans, P. J., 2016

  Supervisor: Corcoran, J. P. T. (Supervisor) & Doherty, P. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The role of peroxisome defects in hearing impairment

  Author: Kochaj, R. M., 1 Sept 2019

  Supervisor: Steel, K. (Supervisor) & McNaughton, P. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• The role of Neuropeptide Y and peptide YY in the gender-specific gastrointestinal, feeding and corticosterone responses to stress

  Author: Forbes, S. C. & Cox, H. M., 2014

  Supervisor: Cox, H. M. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• The role of mitochondrial dysfunction and oxidative stress in paclitaxel-induced painful peripheral neuropathy

  Author: Griffiths, L. A., 2014

  Supervisor: Flatters, S. J. L. (Supervisor) & Bevan, S. J. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• The Role of GPR84 in Chronic Pain Mechanisms

  Author: Nicol, L., 2014

  Supervisor: Malcangio, M. A. M. (Supervisor) & McMahon, S. B. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The Role of Fascin and Drebrin in Neuroblast Migration in the Postnatal Brain

  Author: Sonego, M., 2014

  Supervisor: Lalli, G. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The Regenerative Role of Retinoids in Emphysematous Postnatal Mouse Lungs

  Author: Annan, A., 2014

  Supervisor: Doherty, P. (Supervisor) & Tear, G. J. C. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Therapeutic potential of targeting group III metabotropic glutamate receptors as a disease modifying strategy in the treatment of Parkinson’s disease

  Author: Betts, M., Jun 2012

  Supervisor: Duty, S. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• The involvement of HCN2 ion channels in opioid-induced hyperalgesia and tolerance

  Author: Han, X., 1 Jul 2023

  Supervisor: McNaughton, P. (Supervisor) & Bannister, K. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• The Identification Of A Novel Mechanism By Which Vincristine Sulphate Causes Painful Peripheral Neuropathy

  Author: Old, L. & Old, E., 2013

  Supervisor: Malcangio, M. A. M. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Targeting Chondroitin Sulfate Proteoglycans to promote repair and functional recovery following spinal cord injury

  Author: Burnside, E. R., 2017

  Supervisor: Bradbury, E. J. (Supervisor) & Burrone, J. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Studies of plasticity after neuronal injury

  Author: Bosch, K., Apr 2013

  Supervisor: McMahon, S. B. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Sleep disturbance in people with dementia living in care homes: development of a night-time care programme, NightCAP

  Author: Nunez, K., 1 May 2019

  Supervisor: Corbett, A. (Supervisor), Ballard, C. (Supervisor) & Francis, P. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Sleep, Biological Rhythms & Headache

  Author: Nesbitt, A., 1 Nov 2020

  Supervisor: Goadsby, P. (Supervisor), Rosenzweig, I. (Supervisor) & Dijk, D. (External person) (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Sensory Transduction in Enteroendocrine Cells

  Author: Bircher, J., 1 Apr 2013

  Supervisor: Bevan, S. J. (Supervisor) & Cox, H. M. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Roles of TRPM8 and TRPM3 in sensory transduction

  Author: Quallo, T. E., 2015

  Supervisor: Bevan, S. J. (Supervisor) & Flatters, S. J. L. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Regulation of DAG Lipase Activity – Implications for ‘On-Demand’ Endocannabinoid Signalling

  Author: Markwick, R. L. L., 2015

  Supervisor: Williams, G. (Supervisor) & Doherty, P. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Quality of life and care needs of people with Alzheimer’s disease

  Author: Khan, Z., 1 Sept 2021

  Supervisor: Ballard, C. (Supervisor) & Francis, P. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Pharmacological characterisation of selective Y4 and dual Y2/Y4 receptor agonists: novel targets for putative anti-obesity therapies

  Author: Jolly, N. & Cox, H. M., 2014

  Supervisor: Cox, H. M. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Pharmacological characterisation of selective Y4 and dual Y2/Y4 receptor agonists: novel targets for putative anti-obesity therapies

  Author: Jolly, S., 1 Nov 2013

  Supervisor: Cox, H. M. (Supervisor) & Brain, S. D. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• New therapeutic targets for neuronal ceroid lipofuscinosis (Batten disease)

  Author: Repschlaeger, C., 1 May 2020

  Supervisor: Cooper, J. (Supervisor), Bradbury, E. (Supervisor) & Thuret, S. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Neurotrophin-3 as a promoter of spinal cord plasticity in a distal middle cerebral artery occlusion model of stroke

  Author: Wayman, C., 1 Mar 2017

  Supervisor: Moon, L. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Neuroprotective Effects of FGF20 on Dopamine Neurones

  Author: Boshoff, E., 1 May 2012

  Supervisor: Duty, S. (Supervisor) & Williams, R. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Neuronal and ionic mechanisms of oxaliplatin-induced hypersensitivities and paraesthesias

  Author: Saleque, N., 1 Nov 2021

  Supervisor: Andersson, D. (Supervisor) & Bevan, S. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Neural Repair and Robotics: The In-cage automation of a test for dexterity after stroke.

  Author: Gadiagellan, D., 2018

  Supervisor: Moon, L. D. (Supervisor) & Nanayakkara, T. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Molecular regulation of neuroblast migration in the postnatal brain and intracellular trafficking of Diacylglycerol lipase

  Author: Zhou, Y., 2015

  Supervisor: Doherty, P. (Supervisor) & Lalli, G. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Molecular regulation of neuroblast migration in the postnatal brain

  Author: Gajendra, S., 1 Jan 2013

  Supervisor: Doherty, P. (Supervisor) & Lalli, G. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Machine learning, robotics and neuroplasticity

  Author: Kakanos, S., 1 Jul 2020

  Supervisor: Moon, L. (Supervisor) & Gadiagellan, D. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Isolation of sensory neurons in vitro and generation of a conditional inducible transgenic mouse line against nerve growth factor (NGF) receptors to investigate the role of NGF in pain.

  Author: Kelleher, J. H., 2017

  Supervisor: Raouf, R. K. (Supervisor) & McMahon, S. B. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Investigations of mode of action of single pulse Transcranial Magnetic Stimulation (sTMS) in animal models and effectiveness in migraine patients

  Author: Lloyd, J., 1 Sept 2021

  Supervisor: Antreou, A. (Supervisor) & McMahon, S. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Investigation of neuroinflammation in pain in Parkinson’s disease

  Author: Lama, J., 1 Jun 2023

  Supervisor: Duty, S. (Supervisor), Ray Chaudhuri, K. (Supervisor) & Üçeyler, N. (External person) (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Investigation into mitochondrial DNA, mitochondrial function and nerve activity in oxaliplatin-induced peripheral neuropathy

  Author: Trecarichi, A., 2021

  Supervisor: Flatters, S. (Supervisor), Bevan, S. (Supervisor) & Hamilton-Whitaker, N. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Investigating Unkempt in mTOR signalling and mammalian neurogenesis

  Author: Vinsland, E., 1 Apr 2019

  Supervisor: Bateman, J. (Supervisor), Lalli, G. (Supervisor) & Basson, A. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Investigating the role of phosphorylation in the regulation of Diacylglycerol Lipase α/β activity

  Author: Singh, P., 2013

  Supervisor: Doherty, P. (Supervisor) & Williams, G. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Investigating the novel neurogenic mTOR pathway component Unkempt in Drosophila

  Author: Maierbrugger, K. T., 1 Jul 2019

  Supervisor: Bateman, J. (Supervisor), Lalli, G. (Supervisor) & Sousa-Nunes, R. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Investigating the elemental composition of peripheral sensory nerves and their function in paclitaxel-induced peripheral neuropathy

  Author: Ferguson, C., 1 Apr 2021

  Supervisor: Flatters, S. (Supervisor), McMahon, S. (Supervisor) & Fleck, R. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Investigating the Contribution of the Inflammasome to Persistent Pain States

  Author: Ellis, A., 1 Jul 2013

  Supervisor: Bennett, D. L. H. (Supervisor) & McMahon, S. B. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Investigating synaptic dysfunction in people with Down’s syndrome and Alzheimer’s disease

  Author: Alwesmi, M., 1 Feb 2020

  Supervisor: Francis, P. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

• Investigating pain in Parkinson’s disease and unravelling the underlying mechanisms

  Author: Buhidma, Y. B., 1 Oct 2022

  Supervisor: Duty, S. (Supervisor) & Malcangio, M. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Investigating Nutrient-Sensing Pathways in Ageing Human Neural Stem Cells and Age-Related Cognitive Decline

  Author: De Lucia, C., 1 Apr 2019

  Supervisor: Thuret, S. (Supervisor), Dobson, R. (Supervisor), Proitsi, P. (Supervisor) & Maruszak, A. E. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Investigating neuronal mitochondrial DNA loss in Drosophila melanogaster

  Author: Cagin, U., 1 Apr 2013

  Supervisor: Bateman, J. M. (Supervisor) & Ballard, C. G. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Investigating mitochondrial dysfunction in the nervous system

  Author: Gatt, A. P., 2015

  Supervisor: Bateman, J. M. (Supervisor) & Ballard, C. G. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Investigating Mechanisms of Pain in Alzheimer’s Disease

  Author: Aman, Y., 2018

  Supervisor: Malcangio, M. A. M. (Supervisor) & Ballard, C. G. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Investigating mechanisms of odontogenic pain: the role of odontoblasts, trigeminal ganglion neurons, and their interaction

  Author: Gaurilcikaite, E., 1 Apr 2019

  Supervisor: Grant, A. (Supervisor) & McMahon, S. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Investigating histone deacetylase four in sensory neurons

  Author: Crow, M., 2014

  Supervisor: McMahon, S. B. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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• Investigating group III metabotropic glutamate receptors as novel therapeutic targets in Parkinson’s disease and Levodopa-induced dyskinesia

  Author: Finlay, C. J., 2014

  Supervisor: Duty, S. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy

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