David Edwards

2007

The effect of temperature on the QTc interval in the newborn infant receiving extracorporeal membrane oxygenation (ECMO)

Horan, M., Edwards, A. D., Firmin, R. K., Ablett, T., Rawson, H. & Field, D., Apr 2007, In: Early Human Development. 83, 4, p. 217-223 7 p., N/A.

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Three-tesla cardiac magnetic resonance imaging for preterm infants

Foran, A. M., Fitzpatrick, J. A., Allsop, J., Schmitz, S., Franklin, J., Pamboucas, C., O'Regan, D., Hajnal, J. V. & Edwards, A. D., Jul 2007, In: Pediatrics. 120, 1, p. 78-83 6 p.

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

2006

Abnormal cortical development after premature birth shown by altered allometric scaling of brain growth

Kapellou, O., Counsell, S. J., Kennea, N., Dyet, L., Saeed, N., Stark, J., Maalouf, E., Duggan, P., Ajayi-Obe, M., Hajnal, J., Allsop, J. M., Boardman, J., Rutherford, M. A., Cowan, F. & Edwards, A. D., 2006, In: PL o S Medicine. 3, 8, p. e265

Research output: Contribution to journal › Article › peer-review

Open Access

339 Citations (Scopus)

Abnormal deep grey matter development following preterm birth detected using deformation-based morphometry

Boardman, J. P., Counsell, S. J., Rueckert, D., Kapellou, O., Bhatia, K. K., Aljabar, P., Hajnal, J., Allsop, J. M., Rutherford, M. A. & Edwards, A. D., Aug 2006, In: NeuroImage. 32, 1, p. 70-78 9 p.

Research output: Contribution to journal › Article › peer-review

203 Citations (Scopus)

A major new initiative to improve treatment for children

Smyth, R. L. & Edwards, A. D., Mar 2006, In: Archives of Disease in Childhood. 91, 3, p. 212-213 2 p., N/A.

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

A rapid method for labelling CD4+ T cells with ultrasmall paramagnetic iron oxide nanoparticles for magnetic resonance imaging that preserves proliferative, regulatory and migratory behaviour in vitro

Garden, O. A., Reynolds, P. R., Yates, J., Larkman, D. J., Marelli-Berg, F. M., Haskard, D. O., Edwards, A. D. & George, A. J., 2006, In: Journal of Immunological Methods. 314, 1-2, p. 123-133 11 p.

Research output: Contribution to journal › Article › peer-review

31 Citations (Scopus)

Axial and radial diffusivity in preterm infants who have diffuse white matter changes on magnetic resonance imaging at term-equivalent age

Counsell, S. J., Shen, Y. J., Boardman, J. P., Larkman, D. J., Kapellou, O., Ward, P., Allsop, J. M., Cowan, F. M., Hajnal, J. V., Edwards, A. D. & Rutherford, M. A., Feb 2006, In: Pediatrics. 117, 2, p. 376-386 11 p.

Research output: Contribution to journal › Article › peer-review

224 Citations (Scopus)

Consequential apoptosis in the cerebellum following injury to the developing rat forebrain

Taylor, D. L., Joashi, U. C., Sarraf, C., Edwards, A. D. & Mehmet, H., Jul 2006, In: Brain Pathology. 16, 3, p. 195-201 7 p.

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Detection of vascular expression of E-selectin in vivo with MR imaging

Reynolds, P. R., Larkman, D. J., Haskard, D. O., Hajnal, J. V., Kennea, N. L., George, A. J. T. & Edwards, A. D., Nov 2006, In: Radiology. 241, 2, p. 469-476 8 p.

Research output: Contribution to journal › Article › peer-review

61 Citations (Scopus)

Hypothermia and perinatal asphyxia: executive summary of the National Institute of Child Health and Human Development workshop

Higgins, R. D., Raju, T. N., Perlman, J., Azzopardi, D. V., Blackmon, L. R., Clark, R. H., Edwards, A. D., Ferriero, D. M., Gluckman, P. D., Gunn, A. J., Jacobs, S. E., Eicher, D. J., Jobe, A. H., Laptook, A. R., LeBlanc, M. H., Palmer, C., Shankaran, S., Soll, R. F., Stark, A. R., Thoresen, M., & 1 othersWyatt, J., Feb 2006, In: Journal of Pediatrics. 148, 2, p. 170-175.e1 6 p.

Research output: Contribution to journal › Article › peer-review

163 Citations (Scopus)

Medicines for children

Smyth, R. L. & Edwards, A. D., 2006, In: The Lancet. 368, p. 645-646 2 p.

Research output: Contribution to journal › Article › peer-review

Natural history of brain lesions in extremely preterm infants studied with serial magnetic resonance imaging from birth and neurodevelopmental assessment

Dyet, L. E., Kennea, N., Counsell, S. J., Maalouf, E. F., Ajayi-Obe, M., Duggan, P. J., Harrison, M., Allsop, J. M., Hajnal, J., Herlihy, A. H., Edwards, B., Laroche, S., Cowan, F. M., Rutherford, M. A. & Edwards, A. D., 2006, In: Pediatrics. 118, 2, p. 536-548 13 p.

Research output: Contribution to journal › Article › peer-review

421 Citations (Scopus)

Perinatal infections, prematurity and brain injury

Edwards, A. D. & Tan, S., Apr 2006, In: Current Opinion in Pediatrics. 18, 2, p. 119-124 6 p.

Research output: Contribution to journal › Article › peer-review

60 Citations (Scopus)

Reduced fractional anisotropy on diffusion tensor magnetic resonance imaging after hypoxic-ischaemic encephalopathy

Ward, P., Counsell, S., Allsop, J., Cowan, F., Shen, Y., Edwards, D. & Rutherford, M., Apr 2006, In: Pediatrics. 117, 4, p. 619-30 12 p.

Research output: Contribution to journal › Article › peer-review

Smaller cerebellar volumes in very preterm infants at term-equivalent age are associated with the presence of supratentorial lesions

Srinivasan, L., Allsop, J., Counsell, S. J., Boardman, J. P., Edwards, A. D. & Rutherford, M., 2006, In: AJNR Am J Neuroradiol. 27, 3, p. 573-579 7 p., N/A.

Research output: Contribution to journal › Article › peer-review

125 Citations (Scopus)

Sustainable use of continuous positive airway pressure in extremely preterm infants during the first week after delivery

Booth, C., Premkumar, M. H., Yannoulis, A., Thomson, M., Harrison, M. & Edwards, A. D., 2006, In: Archives of Disease in Childhood Fetal and Neonatal Edition. 91, 6, p. F398-402 5 p.

Research output: Contribution to journal › Article › peer-review

39 Citations (Scopus)

Therapeutic hypothermia following perinatal asphyxia

Edwards, A. D. & Azzopardi, D. V., Mar 2006, In: Archives of Disease in Childhood Fetal and Neonatal Edition. 91, 2, p. F127-F131 5 p.

Research output: Contribution to journal › Article › peer-review

91 Citations (Scopus)

2005

Bacteria and inflammatory cells in fetal membranes do not always cause preterm labor

Steel, J. H., Malatos, S., Kennea, N., Edwards, A. D., Miles, L., Duggan, P., Reynolds, P. R., Feldman, R. G. & Sullivan, M. H., Mar 2005, In: Pediatric Research. 57, 3, p. 404-411 8 p., N/A.

Research output: Contribution to journal › Article › peer-review

Open Access

284 Citations (Scopus)

Hypothermia and amiloride preserve energetics in a neonatal brain slice model

Robertson, N. J., Bhakoo, K., Puri, B. K., Edwards, A. D. & Cox, I. J., Aug 2005, In: Pediatric Research. 58, 2, p. 288-296 9 p.

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Maternal origin of inflammatory leukocytes in preterm fetal membranes, shown by fluorescence in situ hybridisation

Steel, J. H., O'Donoghue, K., Kennea, N. L., Sullivan, M. H. & Edwards, A. D., Sept 2005, In: Placenta. 26, 8-9, p. 672-677 6 p.

Research output: Contribution to journal › Article › peer-review

63 Citations (Scopus)

Mild hypothermia and the distribution of cerebral lesions in neonates with hypoxic-ischemic encephalopathy

Rutherford, M. A., Azzopardi, D., Whitelaw, A., Cowan, F., Renowden, S., Edwards, A. D. & Thoresen, M., 1 Oct 2005, In: Pediatrics. 116, 4, p. 1001-1006 6 p.

Research output: Contribution to journal › Article › peer-review

189 Citations (Scopus)

Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomised trial

Gluckman, P. D., Wyatt, J. S., Azzopardi, D., Ballard, R., Edwards, A. D., Ferriero, D. M., Polin, R. A., Robertson, C. M., Thoresen, M., Whitelaw, A. & Gunn, A. J., 2005, In: The Lancet. 365, p. 663-670 8 p.

Research output: Contribution to journal › Article › peer-review

Universal DNA primers amplify bacterial DNA from human fetal membranes and link Fusobacterium nucleatum with prolonged preterm membrane rupture

Cahill, R. J., Tan, S., Dougan, G., O'Gaora, P., Pickard, D., Kennea, N., Sullivan, M. H., Feldman, R. G. & Edwards, A. D., Oct 2005, In: MOLECULAR HUMAN REPRODUCTION. 11, 10, p. 761-766 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

47 Citations (Scopus)

Xenon and hypothermia combine to provide neuroprotection from neonatal asphyxia

Ma, D., Hossain, M., Chow, A., Arshad, M., Battson, R. M., Sanders, R. D., Mehmet, H., Edwards, A. D., Franks, N. P. & Maze, M., Aug 2005, In: Annals of Neurology. 58, 2, p. 182-193 12 p.

Research output: Contribution to journal › Article › peer-review

250 Citations (Scopus)

2004

Diffusion weighted magnetic resonance imaging in term perinatal brain injury: a comparison with ste of lesion and time from birth

Rutherford, M., Counsell, S., Allsop, J., Boardman, J., Kapellou, O., Larkman, D., Hajnal, J., Edwards, D. & Cowan, F., Oct 2004, In: Pediatrics. 114, 4, p. 1004-1014 11 p.

Research output: Contribution to journal › Article › peer-review

218 Citations (Scopus)

Increased lung water and tissue damage in bronchopulmonary dysplasia

Adams, E. W., Harrison, M. C., Counsell, S. J., Allsop, J. M., Kennea, N. L., Hajnal, J. V., Thornton, A. S., Duggan, P. & Edwards, A. D., Oct 2004, In: Journal of Pediatrics. 145, 4, p. 503-507 5 p.

Research output: Contribution to journal › Article › peer-review

35 Citations (Scopus)

Increased osmolality of breast milk with therapeutic additives

Srinivasan, L., Bokiniec, R., King, C., Weaver, G. & Edwards, A. D., Nov 2004, In: Archives of Disease in Childhood Fetal and Neonatal Edition. 89, 6, p. F514-F517 4 p.

Research output: Contribution to journal › Article › peer-review

37 Citations (Scopus)

MR imaging quantification of cerebellar growth following hypoxic-ischemic injury to the neonatal brain

Le Strange, E., Saeed, N., Cowan, F. M., Edwards, A. D. & Rutherford, M. A., 2004, In: AJNR Am J Neuroradiol. 25, p. 463-468 6 p.

Research output: Contribution to journal › Article › peer-review

53 Citations (Scopus)

The role of intrauterine bacteria in brain injury

Sullivan, M. H., Steel, J., Kennea, N., Feldman, R. G. & Edwards, A. D., Feb 2004, In: Acta Paediatrica Supplement. 93, 444, p. 4-5 2 p.

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

2003

An evaluation of deformation-based morphometry applied to the developing human brain and detection of volumetric changes associated with preterm birth

Boardman, J. P., Bhatia, K., Counsell, S., Allsop, J., Kapellou, O., Rutherford, M. A., Edwards, A. D., Hajnal, J. V. & Rueckert, D., 2003, Medical Image Computing and Computer-Assisted Intervention - MICCAI 2003: Proceedings of the 6th International Conference. Ellis, R. E. & Peters, T. M. (eds.). N/A ed. Berlin and New York: Springer Berlin Heidelberg, Vol. N/A. p. 697-704 8 p. (Lecture Notes in Computer Science; vol. 2878).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

15 Citations (Scopus)

Diffusion-weighted imaging of the brain in preterm infants with focal and diffuse white matter abnormality

Counsell, S. J., Allsop, J. M., Harrison, M. C., Larkman, D. J., Kennea, N. L., Kapellou, O., Cowan, F. M., Hajnal, J. V., Edwards, A. D. & Rutherford, M. A., 1 Jul 2003, In: Pediatrics. 112, 1, p. 1-7 7 p.

Research output: Contribution to journal › Article › peer-review

344 Citations (Scopus)

JF relaxation values in the developing preterm brain

Counsell, S. J., Kennea, N. L., Herlihy, A. H., Allsop, J. M., Harrison, M. C., Cowan, F. M., Hajnal, J. V., Edwards, B., Edwards, A. D. & Rutherford, M. A., 2003, In: AJNR Am J Neuroradiol. 24, p. 1654-1660 7 p.

Research output: Contribution to journal › Article › peer-review

Magnetic resonance imaging of preterm brain injury

Counsell, S. J., Rutherford, M. A., Cowan, F. M. & Edwards, A. D., 2003, In: Archives of Disease in Childhood Fetal and Neonatal Edition. 88, p. F269-74

Research output: Contribution to journal › Article › peer-review

137 Citations (Scopus)

Pilot investigation of hypothermia in neonates receiving extracorporeal membrane oxygenation

Ichiba, S., Killer, H. M., Firmin, R. K., Kotecha, S., Edwards, A. D. & Field, D., Mar 2003, In: Archives of Disease in Childhood Fetal and Neonatal Edition. 88, 2, p. F128-F133 6 p.

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

T2 relaxation values in the developing preterm brain

Counsell, S. J., Kennea, N. L., Herlihy, A. H., Allsop, J. M., Harrison, M. C., Cowan, F. M., Hajnal, J. V., Edwards, B., Edwards, A. D. & Rutherford, M. A., Sept 2003, In: American Journal of Neuroradiology. 24, 8, p. 1654-1660 7 p.

Research output: Contribution to journal › Article › peer-review

49 Citations (Scopus)

2002

Brain alkaline intracellular pH after neonatal encephalopathy

Robertson, N. J., Cowan, F. M., Cox, I. J. & Edwards, A. D., Dec 2002, In: Annals of Neurology. 52, 6, p. 732-742 11 p., N/A.

Research output: Contribution to journal › Article › peer-review

73 Citations (Scopus)

Improved neuroprotection with hypothermia delayed by 6 hours following cerebral hypoxia-ischemia in the 14-day-old rat

Taylor, D. L., Mehmet, H., Cady, E. B. & Edwards, A. D., 2002, In: Pediatric Research. 51, p. 13-19 7 p.

Research output: Contribution to journal › Article › peer-review

74 Citations (Scopus)

Magnetic resonance imaging of lung water content and distribution in term and preterm infants

Adams, E. W., Counsell, S. J., Hajnal, J. V., Cox, P. N., Kennea, N. L., Thornton, A. S., Bryan, A. C. & Edwards, A. D., 1 Aug 2002, In: American Journal of Respiratory and Critical Care Medicine. 166, 3, p. 397-402 6 p., N/A.

Research output: Contribution to journal › Article › peer-review

41 Citations (Scopus)

MR imaging assessment of myelination in the very preterm brain

Counsell, S. J., Maalouf, E. F., Fletcher, A. M., Duggan, P., Battin, M., Lewis, H. J., Herlihy, A. H., Edwards, A. D., Bydder, G. M. & Rutherford, M. A., 2002, In: AJNR Am J Neuroradiol. 23, p. 872-881 10 p.

Research output: Contribution to journal › Article › peer-review

146 Citations (Scopus)

2001

Comparison of findings on cranial ultrasound and magnetic resonance imaging in preterm infants

Maalouf, E. F., Duggan, P. J., Counsell, S. J., Rutherford, M. A., Cowan, F., Azzopardi, D. & Edwards, A. D., 2001, In: Pediatrics. 107, p. 719-727 9 p.

Research output: Contribution to journal › Article › peer-review

328 Citations (Scopus)

Early Increases in Brain myo-Inositol Measured by Proton Magnetic Resonance Spectroscopy in Term Infants with Neonatal Encephalopathy

Robertson, N. J., Lewis, R. H., Cowan, F. M., Allsop, J. M., Counsell, S. J., Edwards, A. D. & Cox, I. J., 2001, In: Pediatric Research. 50, p. 692-700 9 p.

Research output: Contribution to journal › Article › peer-review

65 Citations (Scopus)

Human CD4(+)CD25(+) cells: a naturally occurring population of regulatory T cells

Ng, W. F., Duggan, P. J., Ponchel, F., Matarese, G., Lombardi, G., Edwards, A. D., Isaacs, J. D. & Lechler, R. I., 2001, In: Blood. 98, 9, p. 2736-2744 9 p.

Research output: Contribution to journal › Article › peer-review

541 Citations (Scopus)

Immunoreactive epidermal growth factor receptors are present in gastrointestinal epithelial cells of preterm infants with necrotising enterocolitis

Fagbemi, A. O., Wright, N., Lakhoo, K. & Edwards, A. D., 2001, In: Early Human Development. 65, p. 1-9 9 p.

Research output: Contribution to journal › Article › peer-review

33 Citations (Scopus)

Intrauterine T-cell activation and increased proinflammatory cytokine concentrations in preterm infants with cerebral lesions

Duggan, P. J., Maalouf, E. F., Watts, T. L., Sullivan, M. H., Counsell, S. J., Allsop, J., Al-Nakib, L., Rutherford, M. A., Battin, M., Roberts, I. & Edwards, A. D., 2001, In: The Lancet. 358, p. 1699-1700 2 p.

Research output: Contribution to journal › Article › peer-review

210 Citations (Scopus)

Monitoring of deep brain temperature in infants using multi-frequency microwave radiometry and thermal modelling

Han, J. W., Van Leeuwen, G. M., Mizushina, S., Van de Kamer, J. B., Maruyama, K., Sugiura, T., Azzopardi, D. V. & Edwards, A. D., 2001, In: Physics in Medicine and Biology. 46, p. 1885-1903 19 p.

Research output: Contribution to journal › Article › peer-review

108 Citations (Scopus)

Placental inflammation and brain injury in preterm infants

Duggan, P. J. & Edwards, A. D., 2001, In: Developmental Medicine and Child Neurology Supplement. 43, s86, p. 16-17 2 p.

Research output: Contribution to journal › Article › peer-review

Prothrombotic disorders and abnormal neurodevelopmental outcome in infants with neonatal cerebral infarction

Mercuri, E., Cowan, F., Gupte, G., Manning, R., Laffan, M., Rutherford, M., Edwards, A. D., Dubowitz, L. & Roberts, I., 2001, In: Pediatrics. 107, p. 1400-1404 5 p.

Research output: Contribution to journal › Article › peer-review

156 Citations (Scopus)

2000

Branched chain amino acids induce apoptosis in neural cells without mitochondrial membrane depolarization or cytochrome c release: implications for neurological impairment associated with maple syrup urine disease

Jouvet, P., Rustin, P., Taylor, D. L., Pocock, J. M., Felderhoff-Mueser, U., Mazarakis, N. D., Sarraf, C., Joashi, U., Kozma, M., Greenwood, K., Edwards, A. D. & Mehmet, H., May 2000, In: Molecular biology of the cell. 11, 5, p. 1919-1932 14 p.

Research output: Contribution to journal › Article › peer-review

107 Citations (Scopus)

Characterization of cerebral white matter damage in preterm infants using 1H and 31P magnetic resonance spectroscopy

Robertson, N. J., Kuint, J., Counsell, T. J., Rutherford, T. A., Coutts, A., Cox, I. J. & Edwards, A. D., Oct 2000, In: Journal of Cerebral Blood Flow and Metabolism. 20, 10, p. 1446-1456 11 p., N/A.

Research output: Contribution to journal › Article › peer-review

Open Access

56 Citations (Scopus)

Fas/CD95/APO-1 can function as a death receptor for neuronal cells in vitro and in vivo and is upregulated following cerebral hypoxic-ischemic injury to the developing rat brain

Felderhoff-Mueser, U., Taylor, D. L., Greenwood, K., Kozma, M., Stibenz, D., Joashi, U. C., Edwards, A. D. & Mehmet, H., Jan 2000, In: Brain Pathology. 10, 1, p. 17-29 13 p.

Research output: Contribution to journal › Article › peer-review

130 Citations (Scopus)

David Edwards

Research output

Search results