Afshan Malik

Afshan Malik

Dr

  • Reader of Diabetes & Mitochondrial Biology, SCMMS Guys
    • 1799
      Citations

    Personal profile

    Research interests

    I am a molecular biologist,  I trained in microbial genetics during my PhD and then moved to human genetics during my postdoctoral training, throughout my work was focused on cloning/characterization of disease genes.

    The major goal of my current research is to understand how diabetes causes damage in the body and to develop methods for direct detection in patients in order to provide assays for detection/ prevention of organ damage. I use various in-vitro, and in-vivo model systems as well as clinical samples in combination with molecular and cellular experimental approaches.  I have active projects within my group on diabetic nephropathy, diabetic retinopathy, and Alzheimer’s disease using patient samples, in-vitro and in-vivo experimental models. My research in the last decade has led me towards trying to understand the role of mitochondrial dysfunction in acquired diseases, and the assays I have developed are now being utilized for other projects, such as neonatal brain injury, fatty liver disease and dementia.

    Research interests (short)

    Mitochondria, diabetes and diabetic complications, diabetic nephropathy, mitochondrial DNA

    Expertise related to UN Sustainable Development Goals

    In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

    • SDG 3 - Good Health and Well-being

    Education/Academic qualification

    Doctor of Philosophy, Genetic Studies with Pseudomonan syringae pathovar pisi, University of London

    Award Date: 1 Jan 1987

    Bachelor of Science, UCL University College London

    Award Date: 1 Jan 1982

    Keywords

    • QP Physiology
    • Molecular Biology
    • mitochondrial DNA
    • qPCR
    • mRNA
    • diabetic kidney disease
    • mitochondrial DNA copy number

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