Search results

• Active

  Targeting Haem Oxygenase-1 to Enable Effective Immunotherapy for Osteosarcoma Pulmonary Metastasis

  Grigoriadis, A. (Primary Investigator) & Arnold, J. (Co-Investigator)

  Sarcoma UK

  1/06/2024 → 30/11/2025

  Project: Research

• Drug repurposing targeting Haem oxygenase-1 (HO-1) for prevention of osteosarcoma growth and metastasis

  Grigoriadis, A. (Primary Investigator)

  Hannah's Willberry Wonder Pony Charity

  1/10/2022 → 30/09/2025

  Project: Research

• Drug Repurposing Targeting Immunomodulatory Haem Oxygenase-1 (HO-1) For Prevention Of Osteosarcoma Growth And Metastasis

  Grigoriadis, A. (Primary Investigator) & Arnold, J. (Co-Investigator)

  Little Princess Trust

  1/10/2021 → 31/03/2025

  Project: Research

• Finished

  Targeting Intracellular Vesicular Trafficking Using A Novel V-Atpase Inhibitor To Ameliorate Pathogenicity Of SARS-Cov-2 And Related Viral Pathogens

  Grigoriadis, A. (Primary Investigator), Long, P. (Co-Investigator) & Malim, M. (Co-Investigator)

  BSAC British Society for Antimicrobial Chemotherapy

  1/11/2020 → 31/01/2023

  Project: Research

• Haem oxygenase-1 (HO-1), a novel druggable target for prevention of osteosarcoma growth and metastasis

  Grigoriadis, A. (Primary Investigator)

  Bone Cancer Research Trust

  1/07/2019 → 7/06/2023

  Project: Research

• Disease modelling of the rare genetic bone disorder, Hajdu-Cheney Syndrome, using pluripotent cells and drug repurposing

  Grigoriadis, A. (Primary Investigator)

  Newlife Foundation

  1/07/2019 → 28/02/2023

  Project: Research

• Targeting FGFR and mTOR Signalling in Osteosarcoma Pathogenesis and Metastasis

  Grigoriadis, A. (Primary Investigator)

  Bone Cancer Research Trust

  1/07/2017 → 30/06/2018

  Project: Research

• SOSTDC1-dependent repair of calvarial bone defects using adipose-derived stem cells

  Liu, K. (Primary Investigator), Grigoriadis, A. (Co-Investigator) & Senarath-Yapa, K. (Co-Investigator)

  1/08/2016 → 31/07/2019

  Project: Research

• The effect of Menatetrenone (MK4), a form of vitamin K2 with direct bone-specific actions, on bone metabolism and vascular calcification (VC) in pre-dialysis chronic kidney disease (CKD)

  Fogelman, I. (Primary Investigator) & Grigoriadis, A. (Co-Investigator)

  1/01/2016 → 31/12/2020

  Project: Research

• Transcriptional control of osteochondrogenic differentiation by the MEF2-TBP complex

  Liu, K. (Primary Investigator), Dionne, M. (Co-Investigator) & Grigoriadis, A. (Co-Investigator)

  1/09/2015 → 31/08/2018

  Project: Research

• Management of osteoporosis and metabolic bone disease using a marine natural product

  Long, P. (Primary Investigator), Grigoriadis, A. (Co-Investigator), Hampson, G. (Co-Investigator) & Spina, D. (Co-Investigator)

  5/01/2015 → 4/01/2016

  Project: Research

• Target validation of a marine natural product for the treatment of osteoporosis

  Long, P. (Primary Investigator) & Grigoriadis, A. (Co-Investigator)

  1/09/2014 → 31/08/2015

  Project: Research

• Embryonic stem cell-based therapy for osteoarthritis

  Gentleman, E. (Primary Investigator) & Grigoriadis, A. (Primary Investigator)

  1/10/2013 → 30/09/2014

  Project: Research

• Embryonic stem cell-based therapy for osteoarthritis

  Grigoriadis, A. (Primary Investigator)

  1/01/2013 → 31/12/2013

  Project: Research

• Enhanced prediction of invasive potential of DCIS of the breast (budget for years 1-2 of 3)

  Pinder, S. (Primary Investigator), Brown, J. (Co-Investigator), Grigoriadis, A. (Co-Investigator) & Grigoriadis, A. (Co-Investigator)

  Breast Cancer Research Trust

  1/10/2012 → 30/09/2015

  Project: Research

• Embryonic stem cell-based therapy for osteiarthritis in murine models

  Grigoriadis, A. (Primary Investigator)

  1/08/2012 → 31/07/2015

  Project: Research

• PREDICT-OS

  Grigoriadis, A. (Primary Investigator) & Umpleby, A. (Co-Investigator)

  1/11/2011 → 31/10/2014

  Project: Research

• Binding immunoglobulin protein (BiP): a novel inhibitor of bone destruction by induction of regulatory T cells

  Corrigall, V. (Primary Investigator), Grigoriadis, A. (Primary Investigator) & Panayi, G. (Primary Investigator)

  1/06/2011 → 31/05/2014

  Project: Research

• PREDICT-OS

  Grigoriadis, A. (Primary Investigator)

  1/04/2011 → 31/03/2015

  Project: Research

• Binding immunoglobulin protein (BiP) is a novel negative regulator of osteoclast (OC) differentiation and function

  Corrigall, V. (Primary Investigator), Grigoriadis, A. (Primary Investigator), Panayi, G. (Primary Investigator), Hampson, G. (Co-Investigator) & Henderson, B. (Co-Investigator)

  1/01/2010 → 31/12/2012

  Project: Research

• Binding immunooglobin protein (BiP) is a novel negative regulator of osteoclast differentiation and function

  Corrigall, V. (Primary Investigator), Grigoriadis, A. (Co-Investigator), Hampson, G. (Co-Investigator), Henderson, B. (Co-Investigator) & Panayi, G. (Co-Investigator)

  1/10/2009 → 30/09/2012

  Project: Research

• FGF Receptor signalling in the pathogenesis of human osteosarcoma

  Grigoriadis, A. (Primary Investigator), Buxton, P. (Co-Investigator), Flanagan, A. (Co-Investigator) & Wietek, D. S. (Co-Investigator)

  1/05/2009 → 30/04/2012

  Project: Research

• Growth factor receptor signalling pathways in the treatment, diagnosis and pathogenesis of human osteosarcoma

  Grigoriadis, A. (Primary Investigator) & Weekes, D. (Co-Investigator)

  Guy's & St Thomas' Charity

  1/03/2009 → 31/05/2012

  Project: Research

• The role of FGFR signalling in the pathogenesis of human skeletal malignancies

  Grigoriadis, A. (Primary Investigator), Athanasou, N. (Co-Investigator), Buxton, P. (Co-Investigator) & Flanagan, A. (Co-Investigator)

  1/10/2008 → 30/09/2010

  Project: Research

• Targeting FGF receptor signalling for the treatment of osteosarcoma

  Grigoriadis, A. (Primary Investigator) & Weekes, D. (Co-Investigator)

  Bone Cancer Research Trust

  1/08/2008 → 31/10/2009

  Project: Research

• Targeting FGF receptor signalling in osteosarcoma

  Grigoriadis, A. (Primary Investigator)

  1/08/2008 → 31/07/2009

  Project: Research

• BiP: A Negative Regulator of Bone Remodelling Targeting the Osteoclast

  Corrigall, V. (Primary Investigator), Grigoriadis, A. (Primary Investigator) & Panayi, G. (Primary Investigator)

  1/03/2008 → 30/11/2008

  Project: Research

• Interactions between FGF receptor signalling and c-Fos/AP-1 in the pathogenesis of human bone and cartilage tumours.

  Grigoriadis, A. (Primary Investigator)

  1/03/2008 → 28/02/2011

  Project: Research

• The role of FGFR signalling in the pathogenesis of human skeletal malignancies

  Grigoriadis, A. (Primary Investigator)

  1/02/2008 → 31/01/2011

  Project: Research

• Identifying a novel role for deregulated fibroblast growth factor receptor signalling in the growth control of human osteosarcoma cell

  Grigoriadis, A. (Primary Investigator) & Weekes, D. (Co-Investigator)

  Bone Cancer Research Trust

  1/07/2007 → 30/09/2008

  Project: Research

• A multi-user confocal laser scanning microscope for live and 3D imaging of craniofacial cellular dynamics

  Green, J. (Primary Investigator), Depew, M. (Co-Investigator), Dietrich, S. (Co-Investigator), Francis-West, P. (Co-Investigator), Grigoriadis, A. (Co-Investigator), Liu, K. (Co-Investigator), Rice, D. (Co-Investigator), Sharpe, P. (Co-Investigator), Sheppard, C. (Co-Investigator), Streit, A. (Co-Investigator), Thomas, B. (Co-Investigator), Thomas, H. (Co-Investigator), Tucker, A. (Co-Investigator) & academic, A. (Co-Investigator)

  BBSRC Biotechnology and Biological Sciences Research Council

  1/01/2007 → 31/12/2007

  Project: Research

• Molecular Mechanisms of Bone Formation and Anabolism - ANABONOS

  Grigoriadis, A. (Primary Investigator)

  EC European Commission

  1/03/2004 → 28/02/2007

  Project: Research

• The Role of RHO Family GTPASES in Osteoblast Differentiation and Bone Formation

  Grigoriadis, A. (Primary Investigator)

  BBSRC Biotechnology and Biological Sciences Research Council

  1/04/2003 → 31/03/2006

  Project: Research

• Functional analysis of the AP-1 complex: using animal and cellular models to examine its roles in development, cancer and diseases

  Grigoriadis, A. (Primary Investigator)

  EC European Commission

  1/01/2003 → 31/12/2005

  Project: Research

• The Regulation of Osteoclast Differentiation and Bone Resorption by Pasteurella Multocida Toxin (PMT)

  Grigoriadis, A. (Primary Investigator)

  Arthritis Research UK

  1/12/2001 → 30/11/2004

  Project: Research

• Interaction between PTH/PTHrP signalling and the c-Fos/AP-1 transcription factor in growth plate development and cartilage differentiation

  Grigoriadis, A. (Primary Investigator)

  Wellcome Trust

  1/01/2000 → 31/12/2002

  Project: Research

• The role of the c-Fos/AP-1 transcription factor in the development and eruption of the murine dentition.

  Grigoriadis, A. (Primary Investigator) & Foxworthy, M. (Co-Investigator)

  Wellcome Trust

  1/04/1999 → 31/03/2002

  Project: Research

• Growth control of osteoblasts in development and bone disease.

  Grigoriadis, A. (Primary Investigator)

  Arthritis Research UK

  1/01/1999 → 31/12/2001

  Project: Research

• Cell cycle gene expression in cartilage cells

  Grigoriadis, A. (Primary Investigator)

  Special Trustees of Guys & St Thomas' Hospital

  1/10/1998 → 30/09/2001

  Project: Research

• C-Fos and bone development

  Grigoriadis, A. (Primary Investigator)

  Royal Society

  1/04/1996 → 31/03/1997

  Project: Research