Research output per year
Research output per year
Personal profile
Research interests
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Complex disease genetics and precision medicine
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Big data application and AI in clinical trials and drug discovery
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Development of proteomic-based biomarkers for Neurodegeneration
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Structural variation analysis in genomics
Education/Academic qualification
Neuroscience , Master in Science, Development of proteomic-based biomarkers for Alzheimer disease, Institute of Psychiatry, Psychology and Neuroscience (IoPPN)
Clinical Neuroscience , Doctor of Philosophy, Understanding Disease Trajectory in Amyotrophic Lateral Sclerosis, King's College London
Medicine, Bachelor of Medicine and Bachelor of Surgery, Misr University for Science and Technology
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 9 Industry, Innovation, and Infrastructure -
SDG 10 Reduced Inequalities -
SDG 16 Peace, Justice and Strong Institutions
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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CYP2D6 variants in amyotrophic lateral sclerosis: an association study of risk and survival
Project MinE ALS Sequencing Consortium, 20 May 2026, (E-pub ahead of print) In: Brain : a journal of neurology. awag178.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Downloads (Pure) -
Telomere length analysis in amyotrophic lateral sclerosis using large-scale whole genome sequence data
Al Khleifat, A., Iacoangeli, A., Jones, A., van Vugt, J., Shatunov, A., Moisse, M., Shatunov, A., Zwamborn, R. A. J., van der Spek, R., Cooper-Knock, J., Topp, S., van Rheenen, W., Kenna, B. J., van Eijk, K. R., Kenna, K. P., Byrne, R. P., López Alonso, V., Opie-Martin, S., Vural, A. & González, Y. & 25 others, , 15 Nov 2022, In: Frontiers in Cellular Neuroscience.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)149 Downloads (Pure) -
Structural variation analysis of 6,500 whole genome sequences in amyotrophic lateral sclerosis
Al Khleifat, A., Iacoangeli, A., Van Vugt, J. J. F. A., Bowles, H., Zwamborn, R. A. J., Moisse, M., Zwamborn, R. A. J., Cooper-Knock, J., Shatunov, A., Jones, A., van Rheenen, W., Opie-Martin, S., Fogh, I., Topp, S., Smith, B., Dobson, R., Shaw, C., Chiò, A., Panades, M. P. & Mora, J. S. & 10 others, , 19 Oct 2021, In: NPJ Genomic medicine.Research output: Contribution to journal › Article › peer-review
File236 Downloads (Pure) -
Stage at which riluzole treatment prolongs survival in patients with amyotrophic lateral sclerosis: a retrospective analysis of data from a dose-ranging study
Fang, T., Al Khleifat, A., Meurgey, J.-H., Jones, A., Leigh, P. N., Bensimon, G. & Al-Chalabi, A., 1 May 2018, In: Lancet Neurology. 17, 5, p. 416-422 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile229 Citations (Scopus)360 Downloads (Pure) -
VariantSurvival: A tool to identify genotype-treatment response
Krannich, T., Sarrias, M., Ben Aribi, H., Shokrof, M., Iacoangeli, A., J Sedlazeck, F., Al-Chalabi, A., Busby, B. & Al Khleifat, A., 11 Oct 2023, In: Frontiers in Bioinformatics. 3, 1277923.Research output: Contribution to journal › Article › peer-review
Open AccessFile38 Downloads (Pure)
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Sex-Specific Target Discovery in ALS: A Data-Driven Precision Medicine Approach
Al Khleifat, A. (Primary Investigator) & Iacoangeli, A. (Co-Investigator)
NESTA National Endowment for Science, Technology and the Arts
1/04/2026 → 31/12/2026
Project: Research
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Validating ALS Molecular Subtypes For Diagnostics And Disease Stratification
Iacoangeli, A. (Primary Investigator), Al Khleifat, A. (Co-Investigator) & Al-Chalabi, A. (Co-Investigator)
1/01/2025 → 28/02/2027
Project: Research
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Integration of epigenetic profile in MND clinical trials design
Al-Chalabi, A. (Primary Investigator) & Al Khleifat, A. (Co-Investigator)
1/04/2022 → 31/10/2026
Project: Research
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Advancing Understanding and Treatment of Motor Neurone Disease through Biomarker Development: UK MND RI and King’s MND Biobank Integration Project
Al Khleifat, A. (Primary Investigator) & Al-Chalabi, A. (Co-Investigator)
MNDA Motor Neurone Disease Association
1/03/2025 → 31/05/2026
Project: Research
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MNDSTaR (MND: MNDSTaR: The King's-LifeArc Solution for Motor Neurone Disease Target Validation
Al Khleifat, A. (Primary Investigator), Al-Chalabi, A. (Co-Investigator), Iacoangeli, A. (Co-Investigator), Mitchell, J. (Co-Investigator) & Smith, B. (Co-Investigator)
1/05/2024 → 31/07/2026
Project: Research
Prizes
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ALS Association Milton Safenowitz Research Fellowship
Al Khleifat, A. (Recipient), 31 Jan 2022
Prize: Fellowship awarded competitively
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ENCALS Young Investigator Award
Al Khleifat, A. (Recipient), 3 Jun 2022
Prize: Prize (including medals and awards)
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King's College London Recognition Awards: 2021/2022 Academic Year
Al Khleifat, A. (Recipient), 14 Feb 2022
Prize: Prize (including medals and awards)
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Motor Neurone Disease Association Lady Edith Wolfson Fellowship
Al Khleifat, A. (Recipient), 31 Jan 2022
Prize: Fellowship awarded competitively