King's College London

• A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration

  Solomon, D. A., Stepto, A., Au, W. H., Adachi, Y., Diaper, D. C., Hall, R., Rekhi, A., Boudi, A., Tziortzouda, P., Lee, Y. B., Smith, B., Bridi, J. C., Spinelli, G., Dearlove, J., Humphrey, D. M., Gallo, J. M., Troakes, C., Fanto, M., Soller, M., Rogelj, B., & 4 othersParsons, R. B., Shaw, C. E., Hortobágyi, T. & Hirth, F., 1 Oct 2018, In: Brain. 141, 10, p. 2908-2924 17 p.

  Research output: Contribution to journal › Article › peer-review

• C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity

  Lee, Y-B., Baskaran, P., Gomez-Deza, J., Chen, H-J., Nishimura, A. L., Smith, B. N., Troakes, C., Adachi, Y., Stepto, A., Petrucelli, L., Gallo, J-M., Hirth, F., Rogelj, B., Guthrie, S. & Shaw, C. E., 15 Dec 2017, In: Human Molecular Genetics. 26, 24, p. 4765-4777 13 p.

  Research output: Contribution to journal › Article › peer-review

• Modelling C9ORF72 hexanucleotide repeat expansion in amyotrophic lateral sclerosis and frontotemporal dementia

  Stepto, A., Gallo, J-M., Shaw, C. E. & Hirth, F., Mar 2014, In: Acta Neuropathologica. 127, 3, p. 377-389 13 p., N/A.

  Research output: Contribution to journal › Literature review › peer-review

• Loss and gain of Drosophila TDP-43 impair synaptic efficacy and motor control leading to age-related neurodegeneration by loss-of-function phenotypes

  Diaper, D., Adachi, Y., Sutcliffe, B., Humphrey, D. M., Elliott, C. J. H., Stepto, A., Ludlow, Z. N., Vanden Broeck, L., Callaerts, P., Dermaut, B., Al-Chalabi, A., Shaw, C. E., Robinson, I. M. & Hirth, F., 15 Apr 2013, In: Human Molecular Genetics. 22, 8, p. 1539-1557 19 p.

  Research output: Contribution to journal › Article › peer-review

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