Research output per year
Research output per year
Personal profile
Research interests (short)
Chromatin remodelling, neurodevelopmental disorders, autism, CHARGE syndrome, FGF signalling, cerebellum development, cerebellar hypoplasia, medulloblastoma
Lab website:
KCL Lab website: http://www.kcl.ac.uk/dentistry/research/divisions/craniofac/ResearchGroups/BassonLab/BassonLab.aspx
Our research group is part of the new MRC Centre for Neurodevelopmental Disorders at King’s College London: https://devneuro.org/cndd/aboutus.php
Biographical details
Albert Basson obtained his PhD from the University of Cambridge in 1996. After post-doctoral training in molecular immunology at the MRC National Institute for Medical Research in London (1996-2001), he was awarded a Wellcome Trust International Prize Travelling Fellowship to initiate studies into the regulation of signaling pathways during embryonic development, first at Mount Sinai School of Medicine, New York City (2001-2002) and then at the MRC Centre for Developmental Neurobiology, King’s College London (2003).
He spent a further two years (2004-2006) at the University of California, San Francisco as a visiting post-doctoral scientist before taking up a position as lecturer in the Department of Craniofacial Development. He is a Reader in the Centre for Craniofacial and Regenerative Biology and a member and theme lead in the MRC Centre for Neurodevelopmental Disorders.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, University of Cambridge
Award Date: 1 Jan 1996
Master in Science, University of Pretoria
Award Date: 1 Jan 1992
Bachelor of Science, University of Pretoria
Award Date: 1 Jan 1991
Bachelor of Science, University of Pretoria
Award Date: 1 Jan 1990
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Collaborations and top research areas from the last five years
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Sprouty1 is a critical regulator of GDNF/RET-mediated kidney induction
Basson, M. A., Akbulut, S., Watson-Johnson, J., Simon, R., Carroll, T. J., Shakya, R., Gross, I., Martin, G. R., Lufkin, T., McMahon, A. P., Wilson, P. D., Costantini, F. D., Mason, I. J. & Licht, J. D., Feb 2005, In: Developmental Cell. 8, 2, p. 229 - 239 11 p.Research output: Contribution to journal › Article › peer-review
313 Citations (Scopus) -
Specific regions within the embryonic midbrain and cerebellum require different levels of FGF signaling during development
Basson, M. A., Echevarria, D., Ahn, C. P., Sudarov, A., Joyner, A. L., Mason, I. J., Martinez, S. & Martin, G. R., Mar 2008, In: Development (Cambridge): for advances in developmental biology and stem cells. 135, 5, p. 889 - 898 10 p.Research output: Contribution to journal › Article › peer-review
116 Citations (Scopus) -
Great vessel development requires biallelic expression of Chd7 and Tbx1 in pharyngeal ectoderm in mice
Randall, V., McCue, K., Roberts, C., Kyriakopoulou, V., Beddow, S., Barrett, A. N., Vitelli, F., Prescott, K., Shaw-Smith, C., Devriendt, K., Bosman, E., Steffes, G., Steel, K. P., Simrick, S., Basson, M. A., Illingworth, E. & Scambler, P. J., 2 Nov 2009, In: The Journal of clinical investigation. 119, 11, p. 3301 - 3310 10 p.Research output: Contribution to journal › Article › peer-review
117 Citations (Scopus) -
Sprouty genes prevent excessive FGF signalling in multiple cell types throughout development of the cerebellum
Yu, T., Yaguchi, Y., Echevarria, D., Martinez, S. & Basson, M. A., 15 Jul 2011, In: Development (Cambridge): for advances in developmental biology and stem cells. 138, 14, p. 2957 - 2968 12 p.Research output: Contribution to journal › Article › peer-review
50 Citations (Scopus) -
Biallelic expression of Tbx1 protects the embryo from developmental defects caused by increased receptor tyrosine kinase signaling
Simrick, S., Szumska, D., Gardiner, J. R., Jones, K., Sagar, K., Morrow, B., Bhattacharya, S. & Basson, M. A., Aug 2012, In: Developmental Dynamics. 241, 8, p. 1310-1324 15 p.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus)
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The role of cerebellar inhibitory interneurons in neurodevelopmental disorders
1/09/2022 → 31/08/2027
Project: Research
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Targeting histone demethylation to reverse age-related cognitive decline
1/10/2021 → 30/09/2025
Project: Research
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Activities
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Frontiers in Molecular Biosciences (Journal)
Albert Basson (Editor)
1 Jul 2020 → …Activity: Publication peer-review and editorial work › Editorial activity
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Frontiers in Molecular Neuroscience (Journal)
Albert Basson (Editor)
1 May 2020 → …Activity: Publication peer-review and editorial work › Editorial activity
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Cells (Journal)
Albert Basson (Editor)
1 May 2020 → …Activity: Publication peer-review and editorial work › Editorial activity
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Charge Syndrome Foundation (External organisation)
Albert Basson (Chair)
1 Jan 2018 → …Activity: Membership › Membership of board
Prizes
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Wellcome Trust International Prize Travelling Fellowship
Basson, Albert (Recipient), 2001
Prize: Fellowship awarded competitively