Alex Ivetic
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Personal profile

Research interests

Alex Ivetic obtained his BSc (Hons) in Biochemistry from Imperial College London. He then embarked on a PhD at the Marie Curie Research Institute (through the Institute of Cancer Research, University of London), where he investigated how DNA replication is triggered during the cell cycle. His first postdoc position was hosted at the National Institute for Medical Research (now part of the Francis Crick Institute), where he began his investigations in cell adhesion molecules and their contribution to immune cell recruitment in inflammation. In his second postdoc position, he used the parallel plate flow chamber to model immune cell interactions with blood vessels in vitro. After successfully obtaining a Research Career Development Award from the Wellcome Trust, Alex moved back to Imperial College London in 2005 to start his own group at the National Heart and Lung Institute to further understand mechanisms underlying immune cell responses to inflammation. Since starting at King’s as a Senior Lecturer, Alex has spent time in the labs of Paul Kubes (Calgary, Canada) and Michael Hickey (Monash, Australia) to gain expertise in intravital microscopy – elaborating his understanding of leukocyte recruitment on an organismal level. The majority of his research now focuses on understanding the mechanisms that regulate leukocyte homing to sites of “sterile injury” (e.g. myocardial infarction and venous thrombosis), and how subverting this process might bring improved outcomes in models of cardiovascular disease. In February 2021, Alex was promoted to Reader in Cardiovascular Biology.

Alex is Postgraduate Research Lead to approximately 100 PGR students within the School of Cardiovascular Sciences and Medicine. He is also the Lead Administrator of the Joint PhD programme between King's and the University of Göttingen's Heart Centre, which spun out from an IRTG1816 award by the DFG and is now in its second 5-year renewal. He has supervised 10 PhD students as primary supervisor (8 graduated and 2 currently in place) and is strongly committed to improving PhD student progress and welfare.

Alex has delivered numerous public engagement seminars relating to his research in well-attended events, such as the Pint of Science and Science Museum Lates.

Research interests (short)

Molecular mechanisms that regulate the initial stages of the “Leukocyte Adhesion Cascade”

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 10 - Reduced Inequalities

Education/Academic qualification

Doctor of Philosophy, Analysis of MCM proteins from Drosophila Melanogaster, Institute of Cancer Research

Award Date: 1 Jan 1998

Bachelor of Science, Imperial College London

Award Date: 1 Jan 1993

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