King's College London

Research portal

Dr Alessandra Borsini

  1. Neurogenic and anti-inflammatory effects of probiotics in Parkinson’s disease: a systematic review of preclinical and clinical evidence

    Leta, V., Chaudhuri, R., Milner, O., Chung-Faye, G., Mitta, V., Pariante, C. M. & Borsini, A., Aug 2021, In: Brain Behaviour and Immunity.

    Research output: Contribution to journalReview articlepeer-review

  2. The role of AQP4 in the pathogenesis of depression, and possible related mechanisms

    Genel, O., Pariante, C. & Borsini, A., Aug 2021, In: Brain Behaviour and Immunity.

    Research output: Contribution to journalReview articlepeer-review

  3. The role of Soluble Epoxide Hydrolase and its Inhibitors in Depression

    Borsini, A., Jul 2021, In: Brain Behaviour and Immunity.

    Research output: Contribution to journalReview articlepeer-review

  4. Mental disorders and risk of COVID-19 related mortality, hospitalization and intensive care unit admission: a systematic review and meta-analysis

    Vai, B., Mazza, M. G., Delli Colli, C., Foiselle, M., Allen, B., Benedetti, F., Borsini, A., Consortium, ECNP. I. & Fusar-Poli, P., Jun 2021, In: The Lancet Psychiatry.

    Research output: Contribution to journalReview articlepeer-review

  5. Omega-3 polyunsaturated fatty acids protect against inflammation through production of LOX and CYP450 lipid mediators: relevance for major depression and for human hippocampal neurogenesis

    Borsini, A., Nicolaou, A., Camacho-Muñoz, D., Kendall, A., Di Benedetto, M. G., Giacobbe, J., Su, K-P. & Pariante, C., Jun 2021, In: Molecular Psychiatry.

    Research output: Contribution to journalArticlepeer-review

  6. Severe mental illness and European COVID-19 vaccination strategies

    De Picker, L. J., Vai, B., Casanova Dias, M., Branchi, I., Benedetti, F., Benros, M. E., Borsini, A., Leza, J. C., Kärkkäinen, H., Männikkö, M., Pariante, C. M., Sönmez Güngör, E., Szczegelniak, A., Tamouza, R., van der Markt, A., Fusar-Poli, P., Beezhold, J. & Leboyer, M., May 2021, In: The Lancet Psychiatry. 8, 5, p. 356-359 4 p.

    Research output: Contribution to journalComment/debatepeer-review

  7. Viewpoint | European COVID-19 exit strategy for people with severe mental disorders: too little, but not yet too late

    ECNP Immuno-NeuroPsychiatry TWG, May 2021, In: Brain, Behavior, and Immunity. 94, p. 15-17 3 p.

    Research output: Contribution to journalReview articlepeer-review

  8. Associations of Dietary Intake on Biological Markers of Inflammation in Children and Adolescents: A Systematic Review

    Bujtor, M., Turner, A. I., Torres, S. J., Esteban-Gonzalo, L., Pariante, C. & Borsini, A., Feb 2021, In: Nutrients. 13, 2, p. 1-29 29 p., 356.

    Research output: Contribution to journalArticlepeer-review

  9. Identifying Causative Mechanisms Linking Early Life Stress to Psycho-Cardio-Metabolic Multi-Morbidity: The EarlyCause Project

    Mariani, N., Borsini, A., Cecil, C. A. M., Heil, K. F., Sebert, S., Walton, E., Jarvelin, M., Felix, J., Mansuy, I. M., Cattaneo, A., Sanz, Y., Penninx, B. W. J. H., Milaneschi, Y., Lamers, F., Herault, Y., Cochrane, G., Pariante, C. & Lekadir, K., Jan 2021, In: PloS one. 16, 1 January, e0245475.

    Research output: Contribution to journalArticlepeer-review

  10. The life-long consequences of prenatal and postnatal stress on the innate and adaptive immune system

    Giacobbe, J., Pariante, C. & Borsini, A., Dec 2020, Immuno-Psychiatry.

    Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

  11. The molecular neurobiology of addiction

    Marrocu, A., Giacobbe, J., Pariante, C. & Borsini, A., Dec 2020, Behavioural Neuroscience Encyclopedia.

    Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

  12. Differential effect of Interferon-alpha treatment on AEA and 2-AG levels

    Zajkowska, Z., Borsini, A., Nikkheslat, N., Russell, A., Romano, G., Tomassi, S., Hepgul, N., Forton, D., Agarwal, K., Hotopf, M., Mondelli, V., Zunszain, P. & Pariante, C., Nov 2020, In: Brain Behavior and Immunity. 90, p. 248-258 11 p., BBI_2020_244.

    Research output: Contribution to journalArticlepeer-review

  13. Diet and Depression: Exploring the Biological Mechanisms of Action

    Marx, W., Lane, M., Hockey, M., Aslam, H., Berk, M., Walder, K., Borsini, A., Firth, J., Pariante, C., Berding, K., Cryan, J. F., Clarke, G., Craig, J. M., Su, K-P., Mischoulon, D., Gomez-Pinilla, F., Foster, J., Cani, P., Thuret, S., Staudacher, H. & 6 others, Sánchez-Villegas, A., Arshad, H., Akbaraly, T., O'Neil, A., Segasby, T. & Jacka, F. N., 9 Oct 2020, In: Molecular Psychiatry.

    Research output: Contribution to journalReview articlepeer-review

  14. The innate immune system and neurogenesis as modulating mechanisms of electroconvulsive therapy in pre-clinical studies

    Giacobbe, J., Pariante, C. & Borsini, A., 1 Oct 2020, In: Journal of Psychopharmacology. 34, 10, p. 1086-1097 12 p.

    Research output: Contribution to journalReview articlepeer-review

  15. Glucocorticoids prime the inflammatory response of human hippocampal cells through up-regulation of inflammatory pathways

    Horowitz, M. A., Cattaneo, A., Cattane, N., Lopizzo, N., Tojo, L., Bakunina, N., Musaelyan, K., Borsini, A., Zunszain, P. A. & Pariante, C. M., 1 Jul 2020, In: Brain, Behavior, and Immunity. 87, 0, p. 777-794 18 p.

    Research output: Contribution to journalArticlepeer-review

  16. Food and Mood: How do diet and nutrition affect mental wellbeing?

    Firth, J., Gangwisch, J. E., Borsini, A., Wootton, R. E. & Mayer, E. A., 29 Jun 2020, In: The BMJ. 369, m2382.

    Research output: Contribution to journalArticlepeer-review

  17. Effects of immunomodulatory drugs on depressive symptoms: A mega-analysis of randomized, placebo-controlled clinical trials in inflammatory disorders

    MRC ImmunoPsychiatry Consortium, 19 Sep 2019, In: Molecular Psychiatry. 25, p. 1275–1285 25.

    Research output: Contribution to journalReview articlepeer-review

  18. Microglial-driven changes in synaptic plasticity: a possible role in major depressive disorder

    Innes, S., Pariante, C. M. & Borsini, A., 1 Apr 2019, In: Psychoneuroendocrinology. 102, p. 236-247 12 p.

    Research output: Contribution to journalArticlepeer-review

  19. Persistent fatigue induced by interferon-alpha: a novel, inflammation-based, proxy model of Chronic Fatigue Syndrome

    Russell, A. E., Hepgul, N., Nikkheslat, N., Borsini, A., Zajkowska, Z., Moll, N., Forton, D., Agarwal, K., Chalder, T., Mondelli, V., Hotopf, M. H., Cleare, A. J., Murphy, G., Foster, G., Wong, T., Gregor, S., Schwarz, M. J., Harrison, N. A., Zunszain, P. A. & Pariante, C. M., 14 Dec 2018, In: Psychoneuroendocrinology. 100, p. 276-285 10 p.

    Research output: Contribution to journalArticlepeer-review

  20. Effects of anti-inflammatory drugs on the expression of tryptophan-metabolism genes by human macrophages

    MRC ImmunoPsychiatry Consortium, Regan, T., Gill, A. C., Clohisey, S. M., Barnett, M. W., Pariante, C. M., Harrison, N. A., Hume, D. A., Bullmore, E. T. & Freeman, T. C., 1 Apr 2018, In: Journal of Leukocyte Biology. 103, 4, p. 681-692 12 p.

    Research output: Contribution to journalArticlepeer-review

  21. Replicable and Coupled Changes in Innate and Adaptive Immune Gene Expression in Two Case-Control Studies of Blood Microarrays in Major Depressive Disorder

    Leday, G. G. R., Vértes, P. E., Richardson, S., Greene, J. R., Regan, T., Khan, S., Henderson, R., Freeman, T. C., Pariante, C. M., Harrison, N. A., Cardinal, R., Hume, D., Wu, Z., Cattaneo, A., Zunszain, P., Borsini, A., Stewart, R., Chandran, D., Carvalho, L., Bell, J. & 11 others, Souza-Teodoro, L., Perry, H., Harrison, N., Drevets, W., Wittenberg, G., Jones, D., Stylianou, A., Perry, V. H., Drevets, W. C., Wittenberg, G. M. & Bullmore, E. T., 1 Jan 2018, In: Biological psychiatry. 83, 1, p. 70-80

    Research output: Contribution to journalArticlepeer-review

  22. Depression as a neuroinflammatory condition

    Borsini, A. & Zunszain, P. A., 2018, Immunopsychiatry.

    Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

  23. Neurogenesis, inflammation and mental health.

    Borsini, A., Sawyer, K. M., Zunszain, P. A. & Pariante, C. M., 2018, Inflammation and Immunity in Depression Basic Science and Clinical Applications. Academic Press, p. 103-113

    Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

  24. Trained innate immunity: a salient factor in the pathogenesis of neuroimmune psychiatric disorders

    Salam, A. P., Borsini, A. & Zunszain, P. A., 12 Dec 2017, In: Molecular Psychiatry. 23, p. 170-176

    Research output: Contribution to journalArticlepeer-review

  25. Interferon-alpha reduces human hippocampal neurogenesis and increases apoptosis via activation of distinct STAT1-dependent mechanisms

    Borsini, A., Cattaneo, A., Malpighi, C., Thuret, S., Harrison, N. A., Bullmore, E., Vértes, P. E., Cardinal, R., Richardson, S., Leday, G., Freeman, T., Hume, D., Regan, T., Wu, Z., Stewart, R., Chandran, D., Carvalho, L., Bell, J., Souza-Teodoro, L. H., Perry, H. & 9 others, Drevets, W., Wittenberg, G. M., Sun, Y., Jones, D., Khan, S., Stylianou, A., Henderson, R. B., Zunszain, P. A. & Pariante, C. M., 10 Oct 2017, In: International Journal of Neuropsychopharmacology.

    Research output: Contribution to journalArticlepeer-review

  26. Rescue of IL-1β−induced reduction of human neurogenesis by omega-3 fatty acids and antidepressants

    Borsini, A., Alboni, S., Tojo, L. M., Horowitz, M. A., Su, K-P., Cannazza, G., Pariante, C. M. & Zunszain, P. A., Oct 2017, In: Brain, Behavior, and Immunity. 65, p. 230-238

    Research output: Contribution to journalArticlepeer-review

  27. Repeated exposure to systemic inflammation and risk of new depressive symptoms among older adults.

    Bell, J. A., Kivimäki, M., Bullmore, E. T., Steptoe, A., Vértes, P. E., Cardinal, R., Richardson, S., Leday, G., Freeman, T., Hume, D., Regan, T., Wu, Z., Pariante, C. M., Cattaneo, A., Zunszain, P. A., Borsini, A., Stewart, R., Chandran, D., Carvalho, L. A., Souza-Teodoro, L. H. & 9 others, Perry, H., Harrison, N., Drevets, W., Wittenberg, G. M., Sun, Y., Jones, D., Khan, S., Stylianou, A. & Henderson, R. B., 2017, In: Translational psychiatry. p. 1-8

    Research output: Contribution to journalArticlepeer-review

  28. Advances in stem cells biology: new approaches to understand depression

    Borsini, A. & Zunszain, P. A., 27 Jul 2016, Stem Cells in Neuroendocrinology. 2016 ed. Springer, p. 123-133 10 p. 10

    Research output: Chapter in Book/Report/Conference proceedingChapter

  29. Depression and anxiety in patients receiving interferon-alpha: the role of illness perceptions

    Hepgul, N., Pariante, C. M., Baraldi, S., Borsini, A., Bufalino, C., Russell, A. E., Agarwal, K., Cleare, A. J., Forton, D. M., Henderson, M. J., Mondelli, V., Ranjith, G. & Hotopf, M. H., 24 Jul 2016, In: Journal of Health Psychology. 23, 11, p. 1405-1414

    Research output: Contribution to journalArticlepeer-review

  30. Absolute Measurements of Macrophage Migration Inhibitory Factor and Interleukin-1-β mRNA Levels Accurately Predict Treatment Response in Depressed Patients

    Cattaneo, A., Ferrari, C., Uher, R., Bocchio-Chiavetto, L., Riva, M. A., Pariante, C. M. & MRC ImmunoPsychiatry Consortium, 6 Jun 2016, In: International Journal of Neuropsychopharmacology . 19, 10, p. 1-10

    Research output: Contribution to journalArticlepeer-review

  31. The role of inflammatory cytokines as key modulators of neurogenesis

    Borsini, A., Zunszain, P. A., Thuret, S. & Pariante, C. M., Mar 2015, In: Trends in Neurosciences. 38, 3, p. 145-157 13 p.

    Research output: Contribution to journalArticlepeer-review

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