Search results

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  SCFD1 and G2: Investigating the roles of SCFD1 and G2E3 in ALS

  Sreedharan, J. (Primary Investigator), Akcay, I. (Co-Investigator) & Iacoangeli, A. (Co-Investigator)

  Darby Rimmer MND Foundation

  1/06/2025 → 31/05/2027

  Project: Research

• Virtual Clinical Trial Populations in Motor Neuron Disease

  Al-Chalabi, A. (Primary Investigator), Carter, B. (Co-Investigator) & Iacoangeli, A. (Co-Investigator)

  MRC Medical Research Council

  7/05/2025 → 6/11/2026

  Project: Research

• EPSRC DRIVE-Health: A bioinformatics investigation of the role of the gut-brain axis in motor cell disorders using of metagenomics, metabolomics and clinical data

  Iacoangeli, A. (Primary Investigator), Al-Chalabi, A. (Co-Investigator), Curcin, V. (Co-Investigator) & Dobson, R. (Co-Investigator)

  MNDA Motor Neurone Disease Association

  1/02/2025 → 31/01/2029

  Project: Research

• A Large-scale Multi-omics Study To Investigate The Role Of Human Endogenous Retroviruses And Structural Variants In Amyotrophic Lateral Sclerosis

  Iacoangeli, A. (Primary Investigator), Al-Chalabi, A. (Co-Investigator), Breen, G. (Co-Investigator) & Dobson, R. (Co-Investigator)

  MRC Medical Research Council

  1/01/2025 → 31/12/2027

  Project: Research

• Validating ALS Molecular Subtypes For Diagnostics And Disease Stratification

  Iacoangeli, A. (Primary Investigator), Al Khleifat, A. (Co-Investigator) & Al-Chalabi, A. (Co-Investigator)

  MRC Medical Research Council

  1/01/2025 → 30/06/2026

  Project: Research

• EPSRC DRIVE-Health: Predicting clinical outcomes in motor neurone disease using the Foresight pipeline and the electronic health record

  Dobson, R. (Primary Investigator), Curcin, V. (Co-Investigator) & Iacoangeli, A. (Co-Investigator)

  LifeArc

  1/10/2024 → 30/09/2028

  Project: Research

• NIHR Pre-doctoral Fellowship Round 6 Mandegarsadat Miresmaeili

  Iacoangeli, A. (Primary Investigator) & Al-Chalabi, A. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/09/2024 → 28/02/2026

  Project: Research

• MNDSTaR (MND: MNDSTaR: The King's-LifeArc Solution for Motor Neurone Disease Target Validation

  Al Khleifat, A. (Primary Investigator), Al-Chalabi, A. (Co-Investigator), Iacoangeli, A. (Co-Investigator), Mitchell, J. (Co-Investigator) & Smith, B. (Co-Investigator)

  LifeArc

  1/05/2024 → 30/04/2026

  Project: Research

• Validating ALS molecular profiles from the UK biobank as a diagnostic tool

  Iacoangeli, A. (Primary Investigator), Al Khleifat, A. (Co-Investigator), Al-Chalabi, A. (Co-Investigator), Breen, G. (Co-Investigator) & Dobson, R. (Co-Investigator)

  LifeArc

  18/03/2024 → 6/10/2026

  Project: Research

• Validating ALS molecular subtypes as biomarkers for patient stratification

  Iacoangeli, A. (Primary Investigator), Al Khleifat, A. (Co-Investigator), Al-Chalabi, A. (Co-Investigator) & Breen, G. (Co-Investigator)

  MND Scotland

  1/03/2024 → 31/08/2025

  Project: Research

• Identifying Common and Structural Genetic Variants Driving Genetic Associations with Major Depressive Disorder

  Coleman, J. (Primary Investigator) & Iacoangeli, A. (Co-Investigator)

  Medical Research Foundation

  1/05/2022 → 30/04/2026

  Project: Research

• Investigating the role of human endogenous retroviruses in Amyotrophic Lateral Sclerosis using long-read sequencing

  Iacoangeli, A. (Primary Investigator), Al-Chalabi, A. (Co-Investigator), Breen, G. (Co-Investigator) & Dobson, R. (Co-Investigator)

  Rosetrees Trust

  1/01/2022 → 30/09/2025

  Project: Research

• CDT DRIVE-Health: Identification of new classes of genetic susceptibility to myalgic encephalomyelitis (Action for M.E.)

  Cummins, N. (Primary Investigator) & Iacoangeli, A. (Co-Investigator)

  Action for M.E.

  1/10/2021 → 31/07/2025

  Project: Research

• CDT DRIVE-Health: Identification Of New Classes Of Genetic Susceptibility To Myalgic Encephalomyelitis (ME Research UK)

  Cummins, N. (Primary Investigator) & Iacoangeli, A. (Co-Investigator)

  ME Research UK

  1/10/2021 → 31/07/2025

  Project: Research

• The role of transposable elements in motor neuron disease predisposition and pathogenesis

  Iacoangeli, A. (Primary Investigator) & Al-Chalabi, A. (Co-Investigator)

  MNDA Motor Neurone Disease Association

  1/05/2021 → 30/09/2025

  Project: Research

• Not started

  NIHR Pre-doctoral Fellowship Round 5 Dharti Vasant Kumar

  Iacoangeli, A. (Primary Investigator) & Al-Chalabi, A. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/09/2025 → 28/02/2027

  Project: Research

• Finished

  NIHR Pre-doctoral Fellowship John Jammal

  Iacoangeli, A. (Primary Investigator) & Karimi, M. M. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/09/2023 → 28/02/2025

  Project: Research

• NIHR Pre-doctoral Fellowship Round 5 Triparna Roy

  Iacoangeli, A. (Primary Investigator) & Al-Chalabi, A. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/09/2023 → 28/02/2025

  Project: Research

• Validate of a new SNP-based patient stratification pipeline

  Iacoangeli, A. (Primary Investigator) & Al-Chalabi, A. (Co-Investigator)

  Motor Neurone Disease Association

  1/04/2023 → 30/09/2023

  Project: Research

• Validating new promising drug targets in Amyotrophic Lateral Sclerosis

  Iacoangeli, A. (Primary Investigator), Al Khleifat, A. (Co-Investigator), Al-Chalabi, A. (Co-Investigator), Mitchell, J. (Co-Investigator), Smith, B. (Co-Investigator) & Sreedharan, J. (Co-Investigator)

  Alzheimer's Research UK

  1/01/2023 → 31/01/2025

  Project: Research

• NIHR Maudsley BioResource for Mental Health (22-25)

  Breen, G. (Primary Investigator), Al-Chalabi, A. (Co-Investigator), Eley, T. (Co-Investigator), Himmerich, H. (Co-Investigator), Iacoangeli, A. (Co-Investigator), Nicholson, T. (Co-Investigator), Onwumere, J. (Co-Investigator) & Wong, C. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/12/2022 → 31/03/2025

  Project: Research

• Investigating The Role Of Mitochondrial Variation In ALS

  Iacoangeli, A. (Primary Investigator) & Hodgkinson, A. (Co-Investigator)

  Darby Rimmer MND Foundation

  1/09/2022 → 31/08/2024

  Project: Research

• From Biology to Quality of Life in Motor Neuron Disease:MND Genomics Study

  Breen, G. (Primary Investigator), Al-Chalabi, A. (Co-Investigator) & Iacoangeli, A. (Co-Investigator)

  Darby Rimmer MND Foundation

  1/05/2022 → 30/04/2025

  Project: Research

• A multifaceted approach for the identification of novel drug targets and repurposing opportunities in amyotrophic lateral sclerosis

  Pain, O. (Primary Investigator), Al-Chalabi, A. (Co-Investigator) & Iacoangeli, A. (Co-Investigator)

  Alan Turing Institute

  1/04/2022 → 30/06/2022

  Project: Research

• A structural bioinformatics approach to the study of how genetic variations can cause MND/ALS

  Al-Chalabi, A. (Primary Investigator) & Iacoangeli, A. (Co-Investigator)

  Motor Neurone Disease Association

  1/04/2022 → 30/09/2023

  Project: Research

• NIHR Pre-doctoral Fellowship Yuen Kaye Li

  Iacoangeli, A. (Primary Investigator) & Al-Chalabi, A. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/09/2021 → 28/02/2023

  Project: Research

• A whole-genome sequencing approach to advance precision medicine and study patient heterogeneity in Motor Neurone Disease

  Al-Chalabi, A. (Primary Investigator) & Iacoangeli, A. (Co-Investigator)

  Motor Neurone Disease Association

  1/10/2020 → 31/03/2024

  Project: Research

• NIHR Pre-doctoral Fellowship

  Breen, G. (Primary Investigator) & Iacoangeli, A. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/10/2020 → 31/03/2022

  Project: Research

• DRIVE Health CDT: A whole-genome sequencing approach to advance precision medicine and study patient heterogeneity in ALS

  Al-Chalabi, A. (Primary Investigator), Curcin, V. (Co-Investigator), Dobson, R. (Co-Investigator) & Iacoangeli, A. (Co-Investigator)

  GSK Glaxo Wellcome Research & Development Ltd

  1/10/2020 → 31/03/2024

  Project: Research

• Using statistical models and machine learning to find subgroups of patients with homogeneous disease causes in amyotrophic lateral sclerosis

  Iacoangeli, A. (Primary Investigator), Al-Chalabi, A. (Co-Investigator) & Dobson, R. (Co-Investigator)

  Motor Neurone Disease Association

  1/10/2019 → 30/09/2020

  Project: Research

  • Amyotrophic Lateral Sclerosis 100%
  • Diseases 100%

• A whole-genome approach to the study of the genetic and the epigenetic landscape of Primary Lateral Sclerosis

  Al-Chalabi, A. (Primary Investigator) & Iacoangeli, A. (Co-Investigator)

  Spastic Paraplegia Foundation, Inc

  15/06/2019 → 31/08/2022

  Project: Research

• Multi-omics analysis of human endogenous retroviruses in ALS

  Al-Chalabi, A. (Primary Investigator), Iacoangeli, A. (Co-Investigator) & Dobson, R. (Co-Investigator)

  MND Scotland

  15/06/2019 → 14/06/2020

  Project: Research

  • Multi-Omics 100%
  • Endogenous Retrovirus 100%