King's College London

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Dr Alice Egerton

  1. Accepted/In press
  2. Neuroimaging studies of GABA in schizophrenia: A systematic review with meta-analysis

    Egerton, A., Modinos, G., Ferrera, D. & McGuire, P. 6 Jun 2017 In : Translational psychiatry. 7, 6, e1147

    Research output: Contribution to journalReview article

  3. Elevated Striatal Dopamine Function in Immigrants and Their Children: A Risk Mechanism for Psychosis

    Egerton, A., Howes, O. D., Houle, S., McKenzie, K., Valmaggia, L. R., Bagby, M. R., Tseng, H-H., Bloomfield, M. A. P., Kenk, M., Bhattacharyya, S., Suridjan, I., Chaddock, C. A., Winton-Brown, T. T., Allen, P., Rusjan, P., Remington, G., Meyer-Lindenberg, A., McGuire, P. K. & Mizrahi, R. 1 Mar 2017 In : Schizophrenia Bulletin. 43, 2, p. 293–301 9 p.

    Research output: Contribution to journalArticle

  4. Treatment-Resistant Schizophrenia Patients Show Elevated Anterior Cingulate Cortex Glutamate Compared to Treatment-Responsive

    Mouchlianitis, E., Bloomfield, M. A. P., Law, V., Beck, K., Selvaraj, S., Rasquinha, N., Waldman, A., Turkheimer, F. E., Egerton, A., Stone, J. & Howes, O. D. 17 Dec 2015 In : Schizophrenia Bulletin. 42, 3, p. 744-752

    Research output: Contribution to journalArticle

  5. Dopamine Function in Cigarette Smokers: an [(18)F]-DOPA PET Study

    Bloomfield, M. A. P., Pepper, F., Egerton, A., Tomasi, G., Mouchlianitis, E., Maximen, L., Veronese, M., Turkheimer, F., Selvaraj, S. & Howes, O. Sep 2014 In : Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 39, 10, p. 2397-2404 8 p.

    Research output: Contribution to journalArticle

  6. Dopaminergic Function in Cannabis Users and Its Relationship to Cannabis-Induced Psychotic Symptoms

    Bloomfield, M. A. P., Morgan, C. J. A., Egerton, A., Kapur, S., Curran, H. V. & Howes, O. D. 15 Mar 2014 In : Biological Psychiatry. 75, 6, p. 470-478 9 p.

    Research output: Contribution to journalArticle

  7. Does human presynaptic striatal dopamine function predict social conformity?

    Stokes, P., Benecke, A., Puraite, J., Bloomfield, M. A., Shotbolt, P., Reeves, S., Lingford-Hughes, A. R., Howes, O. & Egerton, A. Mar 2014 In : Journal of Psychopharmacology. 28, 3, p. 237-243 7 p.

    Research output: Contribution to journalArticle

  8. The Enduring Centrality of Dopamine in the Pathophysiology of Schizophrenia: In Vivo Evidence from the Prodrome to the First Psychotic Episode

    Howes, O., Egerton, A., Demjaha, A., Shotbolt, P., Sommer, I., Murray, R., Kapur, S. & McGuire, P. 5 Dec 2013 Catecholamine Research in the 21st Century : Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. ELSEVIER ACADEMIC PRESS INC, p. 151-152 2 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  9. Midbrain dopamine function in schizophrenia and depression: a post-mortem and positron emission tomographic imaging study

    Howes, O., Williams, M., Ibrahim, K., Leung, G., Egerton, A., McGuire, P. K. & Turkheimer, F. Nov 2013 In : Brain. 136, 11, p. 3242-3251 10 p., N/A

    Research output: Contribution to journalArticle

  10. Accepted/In press

    Dopaminergic function in cannabis users and its relation to cannabis-induced psychotic symptoms

    Bloomfield, M., Morgan, C., Egerton, A., Kapur, S., Curran, V. & Howes, O. 2013 In : Biological Psychiatry.

    Research output: Contribution to journalArticle

  11. Transition to Psychosis Associated With Prefrontal and Subcortical Dysfunction in Ultra High-Risk Individuals

    Allen, P., Luigjes, J., Howes, O., Egerton, A., Hirao, K., Valli, I., Kambeitz, J., Fusar-Poli, P., Broome, M. & McGuire, P. Nov 2012 In : Schizophrenia Bulletin. 38, 6, p. 1268-1276 9 p., N/A

    Research output: Contribution to journalArticle

  12. Striatal dopamine D₂/D₃ receptor binding in pathological gambling is correlated with mood-related impulsivity

    Clark, L., Stokes, P. R., Wu, K., Michalczuk, R., Benecke, A., Watson, B. J., Egerton, A., Piccini, P., Nutt, D. J., Bowden-Jones, H. & Lingford-Hughes, A. R. 15 Oct 2012 In : NeuroImage. 63, 1, p. 40-6 7 p.

    Research output: Contribution to journalArticle

  13. The glutamate hypothesis of schizophrenia: Neuroimaging and drug development

    Egerton, A. & Stone, J. M. 1 Jun 2012 In : CURRENT PHARMACEUTICAL BIOTECHNOLOGY. 13, 8, p. 1500-1512 13 p.

    Research output: Contribution to journalArticle

  14. History of cannabis use is not associated with alterations in striatal dopamine D2/D3 receptor availability

    Stokes, P. R. A., Egerton, A., Watson, B., Reid, A., Lappin, J., Howes, O., Nutt, D. J. & Lingford-Hughes, A. R. Jan 2012 In : Journal of Psychopharmacology. 26, 1, p. 144 - 149 6 p.

    Research output: Contribution to journalArticle

  15. Glutamate and psychosis risk

    Egerton, A., Fusar-Poli, P. & Stone, J. 2012 In : Current Pharmaceutical Design. 18, 4, p. 466-478 13 p.

    Research output: Contribution to journalArticle

  16. Reply to: Hippocampal Glutamate Levels and Striatal Dopamine D-2/3 Receptor Occupancy in Subjects at Ultra High Risk of Psychosis

    Stone, J., Howes, O. D., Egerton, A., Kambeitz, J., Allen, P., Lythgoe, D. J., O'Gorman, R. L., McLean, M. A., Barker, G. J. & McGuire, P. 1 Jul 2011 In : Biological Psychiatry. 70, 1, p. e3 - e4 2 p.

    Research output: Contribution to journalLetter

  17. Altered Relationship Between Hippocampal Glutamate Levels and Striatal Dopamine Function in Subjects at Ultra High Risk of Psychosis

    Stone, J., Howes, O., Egerton, A., Kambeitz, J., Allen, P., Lythgoe, D. J., O'Gorman, R. L., McLean, M. A., Barker, G. J. & McGuire, P. 1 Oct 2010 In : Biological Psychiatry. 68, 7, p. 599 - 602 4 p.

    Research output: Contribution to journalArticle

  18. Significant decreases in frontal and temporal [11C]-raclopride binding after THC challenge

    Stokes, P., Egerton, A., Watson, B., Reid, A., Breen, G., Lingford-Hughes, A., Nutt, D. J. & Mehta, M. A. Oct 2010 In : NeuroImage. 52, 4, p. 1521 - 1527 7 p., N/A

    Research output: Contribution to journalArticle

  19. Further Evaluation of the Carbon11-Labeled D-2/3 Agonist PET Radiotracer PHNO: Reproducibility in Tracer Characteristics and Characterization of Extrastriatal Binding

    Egerton, A., Hirani, E., Ahmad, R., Turton, D. R., Brickute, D., Rosso, L., Howes, O. D., Luthra, S. K. & Grasby, P. M. Apr 2010 In : Synapse. 64, 4, p. 301 - 312 12 p.

    Research output: Contribution to journalArticle

  20. Acute effect of the anti-addiction drug bupropion on extracellular dopamine concentrations in the human striatum: An [C-11]raclopride PET study

    Egerton, A., Shotbolt, J. P., Stokes, P., Hirani, E., Ahmad, R., Lappin, J. M., Reeves, S. J., Mehta, M. A., Howes, O. D. & Grasby, P. M. Mar 2010 In : NeuroImage. 50, 1, p. 260 - 266 7 p.

    Research output: Contribution to journalArticle

  21. The dopaminergic basis of human behaviors: A review of molecular imaging studies

    Egerton, A., Mehta, M. A., Montgomery, A. J., Lappin, J. M., Howes, O., Reeves, S. J., Cunningham, V. J. & Grasby, P. M. Jul 2009 In : Neuroscience and Biobehavioral Reviews. 33, 7, p. 1109 - 1132 24 p.

    Research output: Contribution to journalLiterature review

  22. Subchronic and chronic PCP treatment produces temporally distinct deficits in attentional set shifting and prepulse inhibition in rats

    Egerton, A., Reid, L., McGregor, S., Cochran, S. M., Morris, B. J. & Pratt, J. A. May 2008 In : Psychopharmacology. 198, 1, p. 37-49 13 p.

    Research output: Contribution to journalArticle

  23. Modelling prefrontal cortex deficits in schizophrenia: implications for treatment

    Pratt, J. A., Winchester, C., Egerton, A., Cochran, S. M. & Morris, B. J. Mar 2008 In : British Journal of Pharmacology. 153, Suppl 1, p. S465-70 6 p.

    Research output: Contribution to journalArticle

  24. Modulation of striatal dopamine release by 5-HT2A and 5-HT2C receptor antagonists: [11C]raclopride PET studies in the rat

    Egerton, A., Ahmad, R., Hirani, E. & Grasby, P. M. 2008 In : Psychopharmacology. 200, 4, p. 487-96 10 p.

    Research output: Contribution to journalArticle

  25. The effect of nicotine on striatal dopamine release in man: A [11C]raclopride PET study

    Montgomery, A. J., Lingford-Hughes, A. R., Egerton, A., Nutt, D. J. & Grasby, P. M. Aug 2007 In : Synapse. 61, 8, p. 637-645 9 p., N/A

    Research output: Contribution to journalArticle

  26. Agonist-dependent internalization of D2 receptors: Imaging quantification by confocal microscopy

    Goggi, J. L., Sardini, A., Egerton, A., Strange, P. G. & Grasby, P. M. Apr 2007 In : Synapse. 61, 4, p. 231-41 11 p.

    Research output: Contribution to journalArticle

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