Research output per year
Research output per year
Personal profile
Biographical details
Alice Egerton is a Professor of Neuropsychopharmacology within the Department of Psychosis Studies. Her research applies brain imaging techniques to better understand the neurobiological basis of psychosis and schizophrenia, individual variability in clinical response to antipsychotic medication and mechanisms of action of novel therapeutics. Prof Egerton leads the MSc in Psychiatric Research at the IoPPN.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 5 Gender Equality -
SDG 16 Peace, Justice and Strong Institutions
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Dive into the research topics where Alice Egerton is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 12 Similar Profiles
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Associations between glutamate and cerebral blood flow in treatment resistant schizophrenia during clozapine treatment
Sun, J., Zelaya, F., Sendt, K.-V., McQueen, G., Gillespie, A. L., Lally, J., O'Daly, O., Lythgoe, D., Howes, O., Barker, G., McGuire, P., Maccabe, J. & Egerton, A., Apr 2026, In: Journal of Psychopharmacology. 40, 4, p. 563-573 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Cytokine and C-reactive protein concentrations over 6 months of treatment with clozapine in treatment resistant schizophrenia.
Embleton, K., Bennett, S., Maccabe, J. & Egerton, A., 29 Aug 2026, (Accepted/In press) In: Brain Behaviour and Immunity Health.Research output: Contribution to journal › Article › peer-review
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Diazepam modulates anterior cingulate glutamate levels in people at clinical high-risk for psychosis
Kiemes, A., Livingston, N. R., Lukow, P. B., Knight, S., Jelen, L., Reilly, T., Dima, A., Nettis, M. A., Lythgoe, D. J., Casetta, C., Egerton, A., Spencer, T., De Micheli, A., Fusar-Poli, P., Grace, A. A., Williams, S. C. R., McGuire, P., Davies, C., Stone, J. M. & Modinos, G., 1 Feb 2026, In: International Journal of Neuropsychopharmacology . 29, 2, pyaf078.Research output: Contribution to journal › Article › peer-review
Open AccessFile37 Downloads (Pure) -
Why Is Clozapine Uniquely Effective in Treatment-Resistant Schizophrenia? A Review and Proposal
Murray, R. M., Egerton, A., Gao, Y., Grace, A. A., Howes, O., Jauhar, S., Leucht, S., Chen, E. Y. H., MacCabe, J. H., McCutcheon, R. A., Natesan, S. & Taylor, D., 1 Apr 2026, In: Biological psychiatry. 99, 7, p. 517-526 10 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile13 Citations (Scopus)46 Downloads (Pure) -
Diazepam modulates hippocampal CA1 functional connectivity in people at clinical high-risk for psychosis
Livingston, N. R., Kiemes, A., O'Daly, O., Knight, S. R., Lukow, P. B., Jelen, L. A., Reilly, T. J., Dima, A., Nettis, M. A., Casetta, C., Devenyi, G. A., Spencer, T., De Micheli, A., Fusar-Poli, P., Grace, A. A., Williams, S. C. R., McGuire, P., Chakravarty, M. M., Egerton, A. & Modinos, G., 8 Aug 2025, In: Psychological Medicine. 55, e230.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)148 Downloads (Pure)
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Glutamate-Energetics in Schizophrenia and Treatment Resistance
Egerton, A. (Primary Investigator), Puts, N. (Co-Investigator) & Turkheimer, F. (Co-Investigator)
1/01/2024 → 30/09/2027
Project: Research
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Maudsley BRC: NIHR SLaM BRC
Hotopf, M. (Primary Investigator), Brose, L. (Co-Investigator), Brown, J. (Co-Investigator), Chalder, T. (Co-Investigator), Cleare, A. (Co-Investigator), Coleman, J. (Co-Investigator), Cunningham, J. (Co-Investigator), Dazzan, P. (Co-Investigator), Deluca, P. (Co-Investigator), Desrivieres, S. (Co-Investigator), Di Forti, M. (Co-Investigator), Dobson, R. (Co-Investigator), Drummond, C. (Co-Investigator), Dutta, R. (Co-Investigator), Egerton, A. (Co-Investigator), Emsley, R. (Co-Investigator), Gilchrist, G. (Co-Investigator), Gillett, A. (Co-Investigator), Goadsby, P. (Co-Investigator), Happe, F. (Co-Investigator), Hirsch, C. (Co-Investigator), Hoffmann, J. (Co-Investigator), Ismail, K. (Co-Investigator), Koutsouleris, N. (Co-Investigator), Lewis, C. (Co-Investigator), Marsden, J. (Co-Investigator), McAlonan, G. (Co-Investigator), McNeill, A. (Co-Investigator), Mehta, M. (Co-Investigator), Mondelli, V. (Co-Investigator), Moran, R. (Co-Investigator), Moss-Morris, R. (Co-Investigator), Neale, J. (Co-Investigator), Pariante, C. (Co-Investigator), Pile, V. (Co-Investigator), Powell, T. (Co-Investigator), Robson, D. (Co-Investigator), Rucker, J. (Co-Investigator), Schmidt, U. (Co-Investigator), Sonuga-Barke, E. (Co-Investigator), Stahl, D. (Co-Investigator), Stewart, R. (Co-Investigator), Strang, J. (Co-Investigator), Sweeney, A. (Co-Investigator), Turkheimer, F. (Co-Investigator), Vassos, E. (Co-Investigator), Wong, C. (Co-Investigator), Wykes, T. (Co-Investigator), Young, A. (Co-Investigator), Zahn, R. (Co-Investigator) & Zelaya, F. (Co-Investigator)
NIHR National Institute For Health & Care Research
1/12/2022 → 30/11/2027
Project: Research
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Mechanisms of action of clozapine in schizophrenia
Egerton, A. (Primary Investigator) & Maccabe, J. (Co-Investigator)
NIHR National Institute For Health & Care Research
1/01/2023 → 31/08/2025
Project: Research
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Neurobiology of response to clozapine in treatment resistant schizophrenia
Egerton, A. (Primary Investigator), Barker, G. (Co-Investigator), Howes, O. (Co-Investigator), Maccabe, J. (Co-Investigator), McGuire, P. (Co-Investigator), Stone, J. (Co-Investigator) & Zelaya, F. (Co-Investigator)
1/02/2017 → 31/08/2018
Project: Research
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Neural and behavioural correlates of emotional dysfunction in individuals at risk of schizophrenia
Modinos, G. (Primary Investigator), Barker, G. (Co-Investigator), Egerton, A. (Co-Investigator) & McGuire, P. (Co-Investigator)
Brain and Behavior Research Foundation
15/02/2015 → 14/02/2016
Project: Research
Datasets
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Longitudinal resting state fMRI over 12 weeks clozapine in treatment resistant schizophrenia
Egerton, A., King's College London, 20 Mar 2024
DOI: 10.18742/25360018, https://kcl.figshare.com/articles/dataset/Longitudinal_resting_state_fMRI_over_12_weeks_clozapine_in_treatment_resistant_schizophrenia/25360018
Dataset
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Dataset used in paper ‘Evaluation of [13N]ammonia positron emission tomography as a potential method for quantifying glutamine synthetase activity in the human brain.’ (Egerton A and Dunn JT et al 2020)
Dunn, J., Egerton, A., Gee, A. & Hammers, A., King's College London, 20 Nov 2020
DOI: 10.18742/rdm01-667, https://kcl.figshare.com/articles/dataset/Dataset_used_in_paper_Evaluation_of_13N_ammonia_positron_emission_tomography_as_a_potential_method_for_quantifying_glutamine_synthetase_activity_in_the_human_brain_Egerton_A_and_Dunn_JT_et_al_2020_/16473936
Dataset