King's College London

Research portal

Dr Alison Brewer

  1. Inducibility, but not stability, of atrial fibrillation is increased by NOX2 overexpression in mice

    Mighiu, A. S., Recalde, A., Ziberna, K., Carnicer, R., Tomek, J., Bub, G., Brewer, A. C., Verheule, S., Shah, A. M., Simon, J. N. & Casadei, B., 1 Oct 2021, In: Cardiovascular Research. 117, 11, p. 2354-2364 11 p.

    Research output: Contribution to journalArticlepeer-review

  2. Nox2-deficient Tregs improve heart transplant outcomes via their increased graft recruitment and enhanced potency: Nox2-deficient Tregs improve heart allograft outcome

    Cellone Trevelin, S., Zampetaki, A., Sawyer, G., Ivetic, A., Brewer, A., Smith, L. A., Marelli-Berg, F. M., Köchl, R., Lechler, R. I., Shah, A. & Lombardi, G., 22 Sep 2021, In: JCI Insight. 6, 18, p. e149301 12 p., e149301.

    Research output: Contribution to journalArticlepeer-review

  3. Endothelial Nox2 Limits Systemic Inflammation and Hypotension in Endotoxemia by Controlling Expression of Toll-Like Receptor 4

    Trevelin, S. C., Sag, C. M., Zhang, M., Alves-Filho, J. C., Cunha, T. M., Santos, C. X. D., Sawyer, G., Murray, T., Brewer, A., Laurindo, F. R. M., Protti, A., Lopes, L. R., Ivetic, A., Cunha, F. Q. & Shah, A. M., 1 Aug 2021, In: Shock (Augusta, Ga.). 56, 2, p. 268-277 10 p.

    Research output: Contribution to journalArticlepeer-review

  4. Endothelial NADPH oxidase 4 protects against angiotensin II-induced cardiac fibrosis and inflammation

    Wang, M., Murdoch, C. E., Brewer, A. C., Ivetic, A., Evans, P., Shah, A. M. & Zhang, M., Apr 2021, In: ESC Heart Failure. 8, 2, p. 1427-1437 11 p.

    Research output: Contribution to journalArticlepeer-review

  5. Physiological interrelationships between NADPH oxidases and chromatin remodelling

    Brewer, A. C., 2021, (Accepted/In press) In: Free Radical Biology and Medicine.

    Research output: Contribution to journalArticlepeer-review

  6. Dysregulation of 2-oxoglutarate-dependent dioxygenases by Hyperglycaemia: Does this link diabetes and vascular disease?

    Green, H. & Brewer, A., 5 Apr 2020, (Accepted/In press) In: Clinical Epigenetics .

    Research output: Contribution to journalReview articlepeer-review

  7. Dynamic Regulation of Epigenetic Demethylation by Oxygen Availability and Cellular Redox

    Lamadema, N., Burr, S. & Brewer, A. C., 17 Dec 2018, (E-pub ahead of print) In: Free Radical Biology and Medicine. 131, p. 282-298

    Research output: Contribution to journalArticlepeer-review

  8. Nox4 reprograms cardiac substrate metabolism via protein O-GlcNAcylation to enhance stress adaptation

    Nabeebaccus, A. A., Zoccarato, A., Hafstad, A. D., Santos, C. X., Aasum, E., Brewer, A. C., Zhang, M., Beretta, M., Yin, X., West, J. A., Schröder, K., Griffin, J. L., Eykyn, T. R., Abel, E. D., Mayr, M. & Shah, A. M., 21 Dec 2017, (E-pub ahead of print) In: JCI Insight. 2, 24, p. 1-16 10.1172/jci.insight.96184.

    Research output: Contribution to journalArticlepeer-review

  9. Redox-Dependent Regulation of Sulfur Metabolism in Biomolecules: Implications for Cardiovascular Health

    Mistry, R. K. & Brewer, A. C., 28 Jul 2017, (E-pub ahead of print) In: Antioxidants & redox signaling.

    Research output: Contribution to journalArticlepeer-review

  10. Redox regulation of gasotransmission in the vascular system: A focus on angiogenesis

    Mistry, R. K. & Brewer, A. C., Jul 2017, In: Free Radical Biology and Medicine. 108, p. 500-516

    Research output: Contribution to journalArticlepeer-review

  11. Distinct Regulatory Effects of Myeloid Cell and Endothelial Cell NAPDH Oxidase 2 on Blood Pressure

    Sag, C. M., Schnelle, M., Zhang, J., Murdoch, C. E., Kossmann, S., Protti, A., Santos, C. X. C., Sawyer, G. J., Zhang, X., Mongue-Din, H., Richards, D. A., Brewer, A. C., Prysyazhna, O., Maier, L. S., Wenzel, P., Eaton, P. J. & Shah, A. M., 30 May 2017, In: Circulation (Baltimore). 135, 22, p. 2163-2177

    Research output: Contribution to journalArticlepeer-review

  12. Mutual regulation of epicardial adipose tissue and myocardial redox state by PPAR-γ/adiponectin signalling

    Antonopoulos, A. S., Margaritis, M., Verheule, S., Recalde, A., Sanna, F., Herdman, L., Psarros, C., Nasrallah, H., Coutinho, P., Akoumianakis, I., Brewer, A. C., Sayeed, R., Krasopoulos, G., Petrou, M., Tarun, A., Tousoulis, D., Shah, A. M., Casadei, B., Channon, K. M. & Antoniades, C., 4 Mar 2016, In: Circulation Research. 118, 5, p. 842-855 14 p.

    Research output: Contribution to journalArticlepeer-review

  13. Targeted redox inhibition of protein phosphatase 1 by Nox4 regulates eIF2α-mediated stress signaling

    Santos, C. X., Hafstad, A. D., Beretta, M., Zhang, M., Molenaar, C., Kopec, J., Fotinou, D., Murray, T. V., Cobb, A. M., Martin, D., Zeh Silva, M., Anilkumar, N., Schröder, K., Shanahan, C. M., Brewer, A., Brandes, R. P., Blanc, E., Parsons, M., Belousov, V., Cammack, R., & 3 othersHider, R. C., Steiner, R. A. & Shah, A. M., 1 Feb 2016, In: The EMBO journal. 35, 2, p. 319-334 16 p.

    Research output: Contribution to journalArticlepeer-review

  14. Transcriptional regulation of cystathionine-γ-lyase in endothelial cells by NADPH oxidase 4-dependent signaling

    Mistry, R. K., Murray, T. V. A., Prysyazhna, O., Martin, D., Burgoyne, J., Santos, C., Eaton, P., Shah, A. M. & Brewer, A. C., 22 Jan 2016, In: Journal of Biological Chemistry. 291, 4, p. 1774-1788 15 p.

    Research output: Contribution to journalArticlepeer-review

  15. NADPH oxidase 4 regulates homocysteine metabolism and protects against acetaminophen-induced liver damage in mice

    Murray, T. V. A., Dong, X., Sawyer, G. J., Caldwell, A., Halket, J., Sherwood, R., Quaglia, A., Dew, T., Anilkumar, N., Burr, S., Mistry, R. K., Martin, D., Schröder, K., Brandes, R. P., Hughes, R. D., Shah, A. M. & Brewer, A. C., 1 Dec 2015, In: Free Radical Biology and Medicine. 89, p. 918-930 13 p.

    Research output: Contribution to journalArticlepeer-review

  16. Contractile Function during Angiotensin-II Activation: Increased Nox2 Activity Modulates Cardiac Calcium Handling via Phospholamban Phosphorylation

    Zhang, M., Prosser, B. L., Bamboye, M. A., Gondim, A. N. S., Santos, C. X., Martin, D., Ghigo, A., Perino, A., Brewer, A. C., Ward, C. W., Hirsch, E., Lederer, W. J. & Shah, A. M., 21 Jul 2015, In: Journal of the American College of Cardiology. 66, 3, p. 261-272 12 p.

    Research output: Contribution to journalArticlepeer-review

  17. Cardiac-targeted NADPH oxidase 4 in the adaptive cardiac remodelling of the murine heart

    Nabeebaccus, A., Hafstad, A., Eykyn, T., Yin, X., Brewer, A., Zhang, M., Mayr, M. & Shah, A., 26 Feb 2015, In: Lancet. 385 Suppl 1, p. S73

    Research output: Contribution to journalArticlepeer-review

  18. The imbalanced redox status in senescent endothelial cells is due to dysregulated Thioredoxin-1 and NADPH oxidase 4

    Goy, C., Czypiorski, P., Altschmied, J., Jakob, S., Rabanter, L. L., Brewer, A. C., Ale-Agha, N., Dyballa-Rukes, N., Shah, A. M. & Haendeler, J., Aug 2014, In: Experimental Gerontology. 56, p. 45-52 8 p.

    Research output: Contribution to journalArticlepeer-review

  19. Reactive oxygen at the heart of metabolism

    Murray, T. V. A., Ahmad, A. & Brewer, A. C., Apr 2014, In: TRENDS IN CARDIOVASCULAR MEDICINE. 24, 3, p. 113-120 8 p., N/A.

    Research output: Contribution to journalLiterature reviewpeer-review

  20. Reductive stress linked to small HSPs, G6PD, and Nrf2 pathways in heart disease

    Brewer, A., Mustafi, S. B., Murray, T., Rajasekaran, N. S. & Benjamin, I. J., 20 Mar 2013, In: ANTIOXIDANTS AND REDOX SIGNALING. 18, 9, p. 1114-1127 14 p.

    Research output: Contribution to journalArticlepeer-review

  21. Activation of TRPC6 channels is essential for lung ischaemia-reperfusion induced oedema in mice

    Weissmann, N., Sydykov, A., Kalwa, H., Storch, U., Fuchs, B., Mederos y Schnitzler, M., Brandes, R. P., Grimminger, F., Meissner, M., Freichel, M., Offermanns, S., Veit, F., Pak, O., Krause, K-H., Schermuly, R. T., Brewer, A. C., Schmidt, H. H. H. W., Seeger, W., Shah, A. M., Gudermann, T., & 2 othersGhofrani, H. A. & Dietrich, A., 2012, In: Nature Communications. 3, 649.

    Research output: Contribution to journalArticlepeer-review

  22. Nox4 regulates Nrf2 and glutathione redox in cardiomyocytes in vivo

    Brewer, AC., Murray, T., Arno, M., Zhang, M., Anilkumar, N., Mann, G. & Shah, AM., 1 Jul 2011, In: Free Radical Biology and Medicine. 51, 1, p. 205 - 215 11 p.

    Research output: Contribution to journalArticlepeer-review

  23. Role of endothelial Nox2 NADPH oxidase in angiotensin II-induced hypertension and vasomotor dysfunction

    Murdoch, C., Alom-Ruiz, SP., Wang, M., Zhang, M., Yu, B., Brewer, AC. & Shah, AM., Jul 2011, In: Basic Research in Cardiology. 106, 4, p. 527 - 538 12 p.

    Research output: Contribution to journalArticlepeer-review

  24. Endothelial Nox4 NADPH oxidase enhances vasodilatation and reduces blood pressure in vivo

    Ray, R., Murdoch, C. E., Wang, M., Santos, C. X., Zhang, M., Alom-Ruiz, S., Anilkumar, N., Ouattara, A., Cave, A. C., Walker, S. J., Grieve, D. J., Charles, R. L., Eaton, P., Brewer, A. C. & Shah, A. M., Jun 2011, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 31, 6, p. 1368-1376 9 p.

    Research output: Contribution to journalArticlepeer-review

  25. Redox signaling in cardiac myocytes

    Xavier Da Costa Dos Santos, C. S., Anilkumar, N., Zhang, M., Brewer, A. C. & Shah, A. M., 1 Apr 2011, In: Free Radical Biology and Medicine. 50, 7, p. 777 - 793 17 p.

    Research output: Contribution to journalLiterature reviewpeer-review

  26. CELL-SPECIFIC ROLE OF NOX2 NADPH OXIDASE IN DEVELOPMENT OF ANGIOTENSIN II-INDUCED CARDIAC FIBROSIS IN VIVO

    Chaubey, S., Murdoch, C. E., Ivetic, A., Yu, B., Vanhoutte, D., Heymans, S., Brewer, A. & Shah, A. M., 2011, In: Heart. 97, p. A77 - A78

    Research output: Contribution to journalMeeting abstract

  27. ENDOTHELIAL-SPECIFIC OVEREXPRESSION OF NOX2 ENHANCES ANGIOTENSIN II-INDUCED CARDIAC DYSFUNCTION AND FIBROSIS

    Murdoch, C. E., Brewer, A., Zhang, M., Vanhoutte, D., Heymans, S. & Shah, A. M., 2010, In: Heart. 96, 4

    Research output: Contribution to journalMeeting abstract

  28. Functional Characterisation of Nox4D Splice Variant of Nox4 NADPH Oxidase Expressed in Vascular Smooth Muscle Cells

    Anilkumari, N. P., Brewer, A. C., Sawyer, I., Eneriz, G. S. J. & Shah, A., 2010, In: Free Radical Biology and Medicine. 49, p. S91-S91

    Research output: Contribution to journalMeeting abstract

  29. Regulation of the Nrf2 Antioxidant Pathway by NOX4 in the Postnatal Heart

    Brewer, A., Murray, T. & Shah, A., 2010, In: Free Radical Biology and Medicine. 49, p. S126-S126

    Research output: Contribution to journalMeeting abstract

  30. NADPH oxidase signaling and cardiac myocyte function

    Akki, A., Zhang, M., Murdoch, C., Brewer, A. & Shah, A. M., Jul 2009, In: Journal of Molecular and Cellular Cardiology. 47, 1, p. 15-22 8 p.

    Research output: Contribution to journalReview articlepeer-review

  31. Redox signalling and miRNA function in cardiomyocytes

    Brewer, A. C. & Shah, A. M., Jul 2009, In: Journal of Molecular and Cellular Cardiology. 47, 1, p. 2 - 4 3 p.

    Research output: Contribution to journalEditorialpeer-review

  32. Positive regulation of the NADPH oxidase NOX4 promoter in vascular smooth muscle cells by E2F

    Zhang, L., Sheppard, O. R., Shah, A. M. & Brewer, A. C., 1 Sep 2008, In: Free Radical Biology and Medicine. 45, 5, p. 679 - 685 7 p.

    Research output: Contribution to journalArticlepeer-review

  33. Nox4 and Nox2 NADPH oxidases mediate distinct cellular redox signaling responses to agonist stimulation

    Anilkumar, N., Weber, R., Zhang, M., Brewer, A. & Shah, A. M., 1 Jul 2008, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 28, 7, p. 1347 - 1354 8 p.

    Research output: Contribution to journalArticlepeer-review

Previous 1 2 Next

Export:RIS BibTex Word PDF - will at most contain 500 items

Search within the list

Refine results

Type

Type

Language

Language

Publication year

Publication year

Meeting and poster abstracts

Meeting and poster abstracts

Open Access Status

Open Access Status

© 2020 King's College London | Strand | London WC2R 2LS | England | United Kingdom | Tel +44 (0)20 7836 5454