King's College London

Research portal

Dr Amy Pooler

  1. Mislocalization of neuronal tau in the absence of tangle pathology in phosphomutant tau knockin mice

    Gilley, J., Ando, K., Seereeram, A., Rodríguez-Martín, T., Pooler, A. M., Sturdee, L., Anderton, B. H., Brion, J-P., Hanger, D. P. & Coleman, M. P., 1 Mar 2016, In: Neurobiology of Aging. 39, p. 1-18 18 p.

    Research output: Contribution to journalArticlepeer-review

  2. Reduced number of axonal mitochondria and tau hypophosphorylation in mouse P301L tau knockin neurons

    Rodríguez-Martín, T., Pooler, A. M., Lau, D. H. W., Mórotz, G. M., De Vos, K. J., Gilley, J., Coleman, M. P. & Hanger, D. P., 1 Jan 2016, In: Neurobiology of disease. 85, p. 1-10 10 p.

    Research output: Contribution to journalArticlepeer-review

  3. A role for tau at the synapse in Alzheimer's disease pathogenesis

    Pooler, A. M., Noble, W. & Hanger, D. P., 1 Jan 2014, In: Neuropharmacology. 76 , Pt A, p. 1-8 8 p., N/A.

    Research output: Contribution to journalArticlepeer-review

  4. Intracellular and Extracellular Roles for Tau in Neurodegenerative Disease

    Hanger, D. P., Lau, D. H. W., Phillips, E. C., Bondulich, M. K., Guo, T., Woodward, B. W., Pooler, A. M. & Noble, W., 2014, In: Journal of Alzheimer's disease : JAD. 40, Supplement 1, p. S37-S45 9 p.

    Research output: Contribution to journalArticlepeer-review

  5. Tau - amyloid interactions in the rTgTauEC model of early Alzheimer's disease suggest amyloid induced disruption of axonal projections and exacerbated axonal pathology

    Pooler, A. M., Polydoro, M., Wegmann, S. K., Pitstick, R., Kay, K. R., Sanchez, L., Carlson, G. A., Gomez-Isla, T., Albers, M. W., Spires-Jones, T. L. & Hyman, B. T., 15 Dec 2013, In: Journal of Comparative Neurology. 521, 18, p. 4236-4248 13 p., N/A.

    Research output: Contribution to journalArticlepeer-review

  6. Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer's disease model

    Polydoro, M., Dzhala, V. I., Pooler, A. M., Nicholls, S. B., McKinney, A. P., Sanchez, L., Pitstick, R., Carlson, G. A., Staley, K. J., Spires-Jones, T. L. & Hyman, B. T., Nov 2013, (E-pub ahead of print) In: Acta Neuropathologica. N/A, N/A, p. N/A 14 p., N/A.

    Research output: Contribution to journalArticlepeer-review

  7. Propagation of tau pathology in Alzheimer's disease: identification of novel therapeutic targets

    Pooler, A. M., Polydoro, M., Wegmann, S., Nicholls, S. B., Spires-Jones, T. L. & Hyman, B. T., 23 Oct 2013, (E-pub ahead of print) In: Alzheimer's research & therapy. 5, 5, p. N/A 49.

    Research output: Contribution to journalArticlepeer-review

  8. Studying synapses in human brain with array tomography and electron microscopy

    Kay, K. R., Smith, C., Wright, A. K., Serrano-Pozo, A., Pooler, A. M., Koffie, R., Bastin, M. E., Bak, T. H., Abrahams, S., Kopeikina, K. J., McGuone, D., Frosch, M. P., Gillingwater, T. H., Hyman, B. T. & Spires-Jones, T. L., 20 Jun 2013, In: Nature Protocols. 8, 7, p. 1366-1380 15 p.

    Research output: Contribution to journalArticlepeer-review

  9. Physiological release of endogenous tau is stimulated by neuronal activity

    Pooler, A. M., Phillips, E. C., Lau, D. H. W., Noble, W. & Hanger, D. P., Apr 2013, In: EMBO Reports. 14, 4, p. 389-394 6 p., N/A.

    Research output: Contribution to journalArticlepeer-review

  10. The intersection of amyloid beta and tau in glutamatergic synaptic dysfunction and collapse in Alzheimer's disease

    Crimins, J. L., Pooler, A., Polydoro, M., Luebke, J. I. & Spires-Jones, T. L., 22 Mar 2013, (E-pub ahead of print) In: AGEING RESEARCH REVIEWS.

    Research output: Contribution to journalReview articlepeer-review

  11. NUB1 modulation of GSK3β reduces tau aggregation

    Richet, E., Pooler, A. M., Rodriguez, T., Novoselov, S. S., Schmidtke, G., Groettrup, M., Hanger, D. P., Cheetham, M. E. & van der Spuy, J., 15 Dec 2012, In: Human Molecular Genetics. 21, 24, p. 5254-5267 14 p.

    Research output: Contribution to journalArticlepeer-review

  12. Dynamic association of tau with neuronal membranes is regulated by phosphorylation

    Pooler, A. M., Usardi, A., Evans, C. J., Philpott, K. L., Noble, W. & Hanger, D. P., Feb 2012, In: Neurobiology of Aging. 33, 2, p. 431.e27-431.e38 431.e27.

    Research output: Contribution to journalArticlepeer-review

  13. Advances in tau-based drug discovery

    Noble, W., Pooler, A. M. & Hanger, D. P., Aug 2011, In: Expert Opinion On Drug Discovery. 6, 8, p. 797 - 810 14 p.

    Research output: Contribution to journalLiterature reviewpeer-review

  14. Copines-1,-2,-3,-6 and-7 show different calcium-dependent intracellular membrane translocation and targeting

    Perestenko, P. V., Pooler, A., Noorbakhshnia, M., Gray, A., Bauccio, C. & McIlhinney, R. A. J., Dec 2010, In: FEBS Journal. 277, 24, p. 5174-5189 16 p.

    Research output: Contribution to journalArticlepeer-review

  15. Functional implications of the association of tau with the plasma membrane

    Pooler, A. M. & Hanger, D. P., Aug 2010, In: Biochemical Society Transactions. 38, 4, p. 1012 - 1015 4 p.

    Research output: Contribution to journalArticlepeer-review

  16. Identification of a novel region of the GABA(B2) C-terminus that regulates surface expression and neuronal targeting of the GABA(B) receptor

    Pooler, A., Gray, A. G. & McIlhinney, R. A. J., Mar 2009, In: European Journal of Neuroscience. 29, 5, p. 869-878 10 p.

    Research output: Contribution to journalArticlepeer-review

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