Research output per year
Research output per year
Research output
- 17 Article
- 17 results
Search results
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2025
Adipose tissue eQTL meta-analysis highlights the contribution of allelic heterogeneity to gene expression regulation and cardiometabolic traits.
Brotman, S. M., El-Sayed Moustafa, J. S., Guan, L., Broadaway, K. A., Wang, D., Jackson, A. U., Welch, R., Currin, K. W., Tomlinson, M., Vadlamudi, S., Stringham, H. M., Roberts, A. L., Lakka, T. A., Oravilahti, A., Fernandes Silva, L., Narisu, N., Erdos, M. R., Yan, T., Bonnycastle, L. L. & Raulerson, C. K. & 14 others, , Jan 2025, In: Nature Genetics. 57, 1, p. 180-192 13 p., e1000888.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Downloads (Pure) -
2024
Genetic effects on the skin methylome in healthy older twins
Shore, C. J., Villicaña, S., El-Sayed Moustafa, J. S., Roberts, A. L., Gunn, D. A., Bataille, V., Deloukas, P., Spector, T. D., Small, K. S. & Bell, J. T., 5 Sept 2024, In: American Journal of Human Genetics. 111, 9, p. 1932-1952 21 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Haematopoietic stem cell-derived immune cells have reduced X chromosome inactivation skewing in systemic lupus erythematosus
Roberts, A., Morea, A., Amar, A., West, M., Karrar, S., Lehane, R., Tombleson, P., Cunninghame Graham, D., Reynolds, J., Wong, C., Morris, D., Small, K. & Vyse, T., 27 Jun 2024, In: Annals of the Rheumatic Diseases.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)142 Downloads (Pure) -
2023
Escape from X-inactivation in twins exhibits intra- and inter-individual variability across tissues and is heritable
Zito, A., Roberts, A., Visconti, A., Rossi, N., Andres Ejarque, R., Nardone, S., El-Sayed Moustafa, J., Falchi, M. & Small, K., 21 Feb 2023, In: PLoS Genetics. 19, 2, e1010556.Research output: Contribution to journal › Article › peer-review
Open Access13 Citations (Scopus) -
2022
ACE2 expression in adipose tissue is associated with cardio-metabolic risk factors and cell type composition-implications for COVID-19
El-Sayed Moustafa, J. S., Jackson, A. U., Brotman, S. M., Guan, L., Villicaña, S., Roberts, A. L., Zito, A., Bonnycastle, L., Erdos, M. R., Narisu, N., Stringham, H. M., Welch, R., Yan, T., Lakka, T., Parker, S., Tuomilehto, J., Seow, J., Graham, C., Huettner, I. & Acors, S. & 16 others, , Aug 2022, In: International Journal of Obesity. 46, 8, p. 1478-1486 9 p.Research output: Contribution to journal › Article › peer-review
Open Access19 Citations (Scopus) -
Age acquired skewed X Chromosome Inactivation is associated with adverse health outcomes in humans
Roberts, A., 2022, (Accepted/In press) In: eLife.Research output: Contribution to journal › Article › peer-review
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Age acquired skewed X Chromosome Inactivation is associated with adverse health outcomes in humans
Roberts, A., Morea, A., Amar, A., Zito, A., El-Sayed Moustafa, J., Tomlinson, M., Bowyer, R., Zhang, X., Christiansen, C., de Oliveira Costeira, R. C., Steves, C., Mangino, M., Bell, J., Wong, C., Vyse, T. & Small, K., 22 Nov 2022, In: eLife. 11Research output: Contribution to journal › Article › peer-review
Open Access13 Citations (Scopus) -
2021
Probable delirium is a presenting symptom of COVID-19 in frail, older adults: a cohort study of 322 hospitalised and 535 community-based older adults
Zazzara, M. B., Penfold, R. S., Roberts, A. L., Lee, K. A., Dooley, H., Sudre, C. H., Welch, C., Bowyer, R. C. E., Visconti, A., Mangino, M., Freidin, M. B., El-Sayed Moustafa, J. S., Small, K. S., Murray, B., Modat, M., Graham, M. S., Wolf, J., Ourselin, S., Martin, F. C. & Steves, C. J. & 1 others, , 8 Jan 2021, In: Age and Ageing. 50, 1, p. 40-48 9 p.Research output: Contribution to journal › Article › peer-review
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Probable delirium is a presenting symptom of COVID-19 in frail, older adults: a cohort study of 322 hospitalised and 535 community-based older adults
Zazzara, M. B., Penfold, R. S., Roberts, A. L., Lee, K. A., Dooley, H., Sudre, C. H., Welch, C., Bowyer, R. C. E., Visconti, A., Mangino, M., Freidin, M. B., El-sayed Moustafa, J. S., Small, K. S., Murray, B., Modat, M., Graham, M. S., Wolf, J., Ourselin, S., Martin, F. C. & Steves, C. J. & 1 others, , 8 Jan 2021, In: Age and Ageing. 50, 1, p. 40-48 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile83 Citations (Scopus)142 Downloads (Pure) -
2020
Cell type-specific genetic regulation of gene expression across human tissues
GTEx Consortium, 11 Sept 2020, In: Science (New York, N.Y.). 369, 6509, eaaz8528.Research output: Contribution to journal › Article › peer-review
Open Access196 Citations (Scopus) -
Genome-wide assessment of genetic risk for systemic lupus erythematosus and disease severity
Chen, L., Wang, Y. F., Liu, L., Bielowka, A., Ahmed, R., Zhang, H., Tombleson, P., Roberts, A. L., Odhams, C. A., Cunninghame Graham, D. S., Zhang, X., Yang, W., Vyse, T. J. & Morris, D. L., 27 Jun 2020, In: Human Molecular Genetics. 29, 10, p. 1745-1756 12 p., ddaa030.Research output: Contribution to journal › Article › peer-review
Open AccessFile86 Citations (Scopus)189 Downloads (Pure) -
2019
Interferon inducible X-linked gene CXorf21 may contribute to sexual dimorphism in Systemic Lupus Erythematosus
Odhams, C. A., Roberts, A. L., Vester, S. K., S T Duarte, C., Beales, C. T., Clarke, A. J., Lindinger, S., Daffern, S. J., Zito, A., Chen, L., Jones, L. L., Boteva, L., Morris, D. L., Small, K. S., Fernando, M. M. A., Cunninghame Graham, D. S. & Vyse, T. J., 31 May 2019, In: Nature Communications. 10, p. 1-15 2164.Research output: Contribution to journal › Article › peer-review
Open AccessFile84 Citations (Scopus)445 Downloads (Pure) -
2018
De novo mutations implicate novel genes in systemic lupus erythematosus
Pullabhatla, V., Roberts, A. L., Lewis, M. J., Mauro, D., Morris, D. L., Odhams, C. A., Tombleson, P., Liljedahl, U., Vyse, S., Simpson, M. A., Sauer, S., de Rinaldis, E., Syvänen, A. C. & Vyse, T. J., 1 Feb 2018, In: Human Molecular Genetics. 27, 3, p. 421-429 9 p.Research output: Contribution to journal › Article › peer-review
Open Access41 Citations (Scopus) -
2017
Mapping eQTLs with RNA-Seq Reveals Novel Susceptibility Genes, Non-Coding RNAs, and Alternative-Splicing Events in Systemic Lupus Erythematosus
Odhams, C. A., Cortini, A., Chen, L., Roberts, A. L., Viñuela, A., Buil, A., Small, K. S., Dermitzakis, E. T., Morris, D. L., Vyse, T. J. & Cunninghame Graham, D. S., 1 Mar 2017, In: Human Molecular Genetics. 26, 5, p. 1003-1017 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile41 Citations (Scopus)298 Downloads (Pure) -
2016
Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus
Morris, D. L., Sheng, Y., Zhang, Y., Wang, Y. F., Zhu, Z., Tombleson, P., Chen, L., Cunninghame Graham, D. S., Bentham, J., Roberts, A. L., Chen, R., Zuo, X., Wang, T., Wen, L., Yang, C., Liu, L., Yang, L., Li, F., Huang, Y. & Yin, X. & 12 others, , 1 Aug 2016, In: Nature Genetics. 48, 8, p. 940–946Research output: Contribution to journal › Article › peer-review
Open AccessFile254 Citations (Scopus)306 Downloads (Pure) -
The complement receptor 3 (CD11b/CD18) agonist Leukadherin-1 suppresses human innate inflammatory signalling
Roberts, A. L., Fürnrohr, B. G., Vyse, T. J. & Rhodes, B., 1 Sept 2016, In: Clinical and Experimental Immunology. 185, 3, p. 361-371 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Citations (Scopus)194 Downloads (Pure) -
2013
Genomic pathology of SLE-associated copy-number variation at the FCGR2C/FCGR3B/FCGR2B locus
Mueller, M., Barros, P., Witherden, A. S., Roberts, A., Zhang, Z., Schaschl, H., Yu, C.-Y., Hurles, M. E., Schaffner, C., Floto, R. A., Game, L., Steinberg, K. M., Wilson, R. K., Graves, T. A., Eichler, E. E., Cook, H. T., Vyse, T. J. & Aitman, T. J., 10 Jan 2013, In: American Journal of Human Genetics. 92, 1, p. 28-40 13 p.Research output: Contribution to journal › Article › peer-review
53 Citations (Scopus)