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Dr Andre Strydom

Biographical details

Andre Strydom is a specialist in the Psychiatry of Intellectual disabilities. Dr. Strydom's research has a specific focus on conditions associated with ageing in intellectual disability (ID) populations, such as Alzheimer's disease in individuals with Down Syndrome (DS). He is an expert in ageing-related issues in Down syndrome and the cognitive phenotype(s) associated with trisomy 21.

Current projects and collaborations include the LonDownS consortium funded by the Wellcome Trust to study the neurobiology of Alzheimer's Disease in Down syndrome. This work concerns detailed cognitive phenotyping of individuals with Down across the lifespan, and tracking change with ageing, as well as collecting DNA, blood and cellular samples. His research in Down syndrome include biomarkers of cognitive decline such those related to Oxidative stress, and neuroimaging such as high-density EEG and fNIRS imaging (funded by the Baily Thomas Fund and the LeJeune Foundation).

Dr Strydom is also involved in developing and testing the efficacy of complex interventions for the treatment of mental disorders in adults with intellectual disabilities such as CBT for anxiety and depression, positive behaviour support for problem behaviours, as well as health checks for people with intellectual disabilities in primary care.

He has been an investigator on industry sponsored trials of new drug treatment options in Down syndrome and fragile X syndrome.

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