Research output per year
Research output per year
Dr, Professor
SE5 8AF
United Kingdom
Andre Strydom is a psychiatrist in Intellectual disabilities. Dr. Strydom's research has a specific focus on conditions associated with ageing in intellectual disability (ID) populations, such as Alzheimer's disease in individuals with Down Syndrome (DS). He is an expert in ageing-related issues in Down syndrome and the cognitive phenotype(s) associated with trisomy 21.
Current projects and collaborations include the LonDownS consortium initially funded by the Wellcome Trust to study the neurobiology of Alzheimer's Disease in Down syndrome, and now funded by the MRC, with a focus on MRI and plasma biomarker changes associated with the development of Alzheimer's disease in individuals with Down syndrome. Working in close collaboration with colleagues in Europe within the HOrizon21 consortium, a major aim is to enable clinical trials for the treatment and prevention of Alzheimer's disease in people with Down syndrome. As part of the Go-DS21 consortium funded by the EC, we are also studying metabolic and cardiovascular status of people with Down syndrome across the lifespan, with the aim to improve clinical guidance on management of these conditions.
Dr Strydom is the lead for KCL's LeDeR programme, tendered by NHSE to address inequalities in healthcare of people with a learning disability and autistic people. He directs the NDD-Clinical trials unit, where we conduct trials of medications and complex interventions (both academic and industry sponsored) to improve conditions associated with intellectual disability, Down syndrome, autism, and fragile X syndrome.
Alzheimer's disease
Down syndrome
Fragile x syndrome
Mental disorders of intellectual disabilities
Genetic aspects of intellectual disabilities
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Sheehan, N. (Primary Investigator), Carter, B. (Co-Investigator), Chinn, D. (Co-Investigator), Downs, J. (Co-Investigator), Jin, H. (Co-Investigator), Stewart, R. (Co-Investigator) & Strydom, A. (Co-Investigator)
NIHR National Institute For Health & Care Research
1/09/2024 → 29/02/2028
Project: Research
Strydom, A. (Primary Investigator)
NIH National Institutes of Health
1/07/2023 → 31/03/2025
Project: Research
Strydom, A. (Primary Investigator), Carter, B. (Co-Investigator) & Sheehan, N. (Co-Investigator)
1/06/2021 → 31/10/2026
Project: Research
Strydom, A. (Primary Investigator)
NIHR National Institute For Health & Care Research
1/04/2020 → 30/09/2025
Project: Research
Murphy, D. (Primary Investigator), McAlonan, G. (Co-Investigator), Loth, E. (Co-Investigator), O'Muircheartaigh, J. (Co-Investigator), Dell' Acqua, F. (Co-Investigator), Daly, E. (Co-Investigator), Strydom, A. (Co-Investigator), Simonoff, E. (Co-Investigator), Richardson, M. (Co-Investigator), Marin, O. (Co-Investigator), Rico, B. (Co-Investigator), Charman, T. (Co-Investigator), Edwards, D. (Co-Investigator), Rutherford, M. (Co-Investigator), Hajnal, J. (Co-Investigator), Hotopf, M. (Co-Investigator) & Dobson, R. (Co-Investigator)
1/06/2018 → 31/05/2025
Project: Research