Research output per year
Research output per year
- 27 results
Search results
-
2023
AMPK is a mechano-metabolic sensor linking cell adhesion and mitochondrial dynamics to Myosin-dependent cell migration
Crosas-Molist, E., Graziani, V., Maiques, O., Pandya, P., Monger, J., Samain, R., George, S. L., Malik, S., Salise, J., Morales, V., Le Guennec, A., Atkinson, R. A., Marti, R. M., Matias-Guiu, X., Charras, G., Conte, M. R., Elosegui-Artola, A., Holt, M. & Sanz-Moreno, V., Dec 2023, In: Nature Communications. 14, 1, 2740.Research output: Contribution to journal › Article › peer-review
Open Access31 Citations (Scopus) -
AMPK is a mechano-metabolic sensor linking cell adhesion and mitochondrial dynamics to Myosin-dependent cell migration
Crosas-Molist, E., Graziani, V., Maiques, O., Pandya, P., Monger, J., Samain, R., George, S. L., Malik, S., Salise, J., Morales, V., Le Guennec, A., Atkinson, R. A., Marti, R. M., Matias-Guiu, X., Charras, G., Conte, M. R., Elosegui-Artola, A., Holt, M. & Sanz-Moreno, V., 22 May 2023, In: Nature Communications. 14, 1, p. 2740Research output: Contribution to journal › Article › peer-review
Open Access -
Revisiting specific force loss in human permeabilized single skeletal muscle fibers obtained from older individuals
Kalakoutis, M., Pollock, R. D., Lazarus, N. R., Atkinson, R. A., George, M., Berber, O., Woledge, R. C., Ochala, J. & Harridge, S. D. R., 1 Jul 2023, In: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 325, 1, p. C172-C185Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
2021
Dipeptide inhibitors of the prostate specific membrane antigen (PSMA): A comparison of urea and thiourea derivatives
Young, J., Ma, M., Eykyn, T., Atkinson, A., Abbate, V., Cilibrizzi, A., Hider, R. & Blower, P., 15 Jun 2021, In: Bioorganic & medicinal chemistry letters. 42, 128044.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)119 Downloads (Pure) -
One-step, kit-based radiopharmaceuticals for molecular SPECT imaging: a versatile diphosphine chelator for 99mTc radiolabelling of peptides
Hungnes, I., Al Salemee, F., Gawne, P., Eykyn, T. R., Atkinson, A., Terry, S., Clarke, F., Blower, P. J., Pringle, P. G. & Ma, M., 28 Nov 2021, In: Dalton Transactions. 50, 44, p. 16156-16165 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)94 Downloads (Pure) -
2020
A Pleurocidin Analogue with Greater Conformational Flexibility, Enhanced Antimicrobial Potency and in vivo Therapeutic Efficacy
Manzo, G., Hind, C. K., Ferguson, P., Amison, R., Hodgson-Casson, A., Ciazynska, K., Weller, B., Clarke, M., Lam, C., Man, R., O'Shaughnessy, B., Clifford, M., Bui, T., Drake, A., Atkinson, A., Lam, J., Pitchford, S., Page, C., Phoenix, D. & Lorenz, C. & 2 others, , 31 Dec 2020, In: Communications Biology. 3, 1, 697.Research output: Contribution to journal › Article › peer-review
Open AccessFile21 Citations (Scopus)179 Downloads (Pure) -
Organocatalytic Access to a cis-Cyclopentyl-γ-amino Acid: An Intriguing Model of Selectivity and Formation of a Stable 10/12-Helix from the Corresponding γ/α-Peptide
Fanelli, R., Berta, D., Földes, T., Rosta, E., Atkinson, R. A., Hofmann, H.-J., Shankland, K. & Cobb, A. J. A., 22 Jan 2020, In: Journal of the American Chemical Society. 142, 3, p. 1382-1393 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Citations (Scopus)138 Downloads (Pure) -
2019
15-deoxy-Δ12,14-Prostaglandin J2 inhibits human soluble epoxide hydrolase by a dual orthosteric and allosteric mechanism
Abis, G., Charles, R. L., Kopec, J., Yue, W. W., Atkinson, R. A., Bui, T. T. T., Lynham, S., Popova, S., Sun, Y.-B., Fraternali, F., Eaton, P. & Conte, M. R., May 2019, In: Communications Biology. 2, 1, 188.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Citations (Scopus)205 Downloads (Pure) -
Controlling the dynamics of the Nek2 leucine zipper by engineering of "kinetic" disulphide bonds
Gutmans, D. S., Whittaker, S.B.-M., Asiani, K., Atkinson, R. A., Oregioni, A. & Pfuhl, M., 1 Feb 2019, In: PLoS ONE. 14, 2, p. e0210352 e0210352.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)194 Downloads (Pure) -
LARP4A recognizes polyA RNA via a novel binding mechanism mediated by disordered regions and involving the PAM2w motif, revealing interplay between PABP, LARP4A and mRNA
Cruz-Gallardo, I., Martino, L., Kelly, G., Atkinson, R. A., Trotta, R., De Tito, S., Coleman, P., Ahdash, Z., Gu, Y., Bui, T. T. T. & Conte, M. R., 7 May 2019, In: Nucleic Acids Research. 47, 8, p. 4272–4291 20 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile31 Citations (Scopus)228 Downloads (Pure) -
Metabolomic and lipidomic plasma profile changes in human participants ascending to Everest Base Camp
O'Brien, K. A., Atkinson, R. A., Richardson, L., Koulman, A., Murray, A. J., Harridge, S. D. R., Martin, D. S., Levett, D. Z. H., Mitchell, K., Mythen, M. G., Montgomery, H. E., Grocott, M. P. W., Griffin, J. L. & Edwards, L. M., 1 Dec 2019, In: Scientific Reports. 9, 2297.Research output: Contribution to journal › Article › peer-review
Open AccessFile40 Citations (Scopus)207 Downloads (Pure) -
Microbial functional change is linked with clinical outcomes after capsular fecal transplant in cirrhosis
Bajaj, J. S., Salzman, N., Acharya, C., Takei, H., Kakiyama, G., Fagan, A., White, M. B., Gavis, E. A., Holtz, M. L., Hayward, M., Nittono, H., Hylemon, P. B., Cox, I. J., Williams, R., Taylor-Robinson, S. D., Sterling, R. K., Matherly, S. C., Fuchs, M., Lee, H. & Puri, P. & 10 others, , 21 Nov 2019, In: JCI Insight. 4, 24, e133410.Research output: Contribution to journal › Article › peer-review
Open Access59 Citations (Scopus) -
Minor sequence modifications in temporin B cause drastic changes in antibacterial potency and selectivity by fundamentally altering membrane activity
Manzo, G., Ferguson, P. M., Gustilo, V. B., Hind, C., Clifford, M., Bui, T., Drake, A., Atkinson, R. A., Sutton, J. M., Batoni, G., Lorenz, C., Phoenix, D. & Mason, A. J., 4 Feb 2019, In: Scientific Reports. 9, 1, 1385.Research output: Contribution to journal › Article › peer-review
Open AccessFile29 Citations (Scopus)347 Downloads (Pure) -
Resonance assignment of human LARP4A La module
Cruz-Gallardo, I., Martino, L., Trotta, R., De Tito, S., Kelly, G., Atkinson, R. A., Randazzo, A. & Conte, M. R., 1 Apr 2019, In: Biomolecular NMR Assignments. 13, 1, p. 169-172 4 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
Temporin L and aurein 2.5 have identical conformations but subtly distinct membrane and antibacterial activities
Manzo, G., Ferguson, P. M., Hind, C. K., Clifford, M., Gustilo, V. B., Ali, H., Bansal, S., Bui, T., Drake, A. F., Atkinson, R. A., Sutton, J. M., Lorenz, C., Phoenix, D. & Mason, A. J., 1 Dec 2019, In: Scientific Reports. 9, 1, 10934.Research output: Contribution to journal › Article › peer-review
Open AccessFile29 Citations (Scopus)249 Downloads (Pure) -
2018
Human physiological and metabolic responses to an attempted winter crossing of Antarctica: the effects of prolonged hypobaric hypoxia
O'Brien, K. A., Pollock, R. D., Stroud, M., Lambert, R. J., Kumar, A., Atkinson, R. A., Green, D. A., Anton-Solanas, A., Edwards, L. M. & Harridge, S. D. R., 9 Mar 2018, In: Physiology Reports. 6, 5Research output: Contribution to journal › Article › peer-review
Open AccessFile32 Citations (Scopus)256 Downloads (Pure) -
Structural and Functional Insights into Bacillus subtilis Sigma Factor Inhibitor, CsfB
Martínez-Lumbreras, S., Alfano, C., Evans, N. J., Collins, K. M., Flanagan, K. A., Atkinson, R. A., Krysztofinska, E. M., Vydyanath, A., Jackter, J., Fixon-Owoo, S., Camp, A. H. & Isaacson, R. L., 8 Mar 2018, (E-pub ahead of print) In: Structure.Research output: Contribution to journal › Article › peer-review
Open Access11 Citations (Scopus) -
2016
Proteomic and metabolomic changes driven by elevating myocardial creatine suggest novel metabolic feedback mechanisms
Zervou, S., Yin, X., A. Nabeebaccus, A., O'Brien, B., L. Cross, R., McAndrew, D. J., Atkinson, A., Eykyn, T., Mayr, M., Neubauer, S. & Lygate, C. A., 3 May 2016, (E-pub ahead of print) In: AMINO ACIDS. p. 1-13 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Citations (Scopus)208 Downloads (Pure) -
2015
(1)H, (15)N and (13)C chemical shift assignments of the La motif and RRM1 from human LARP6
Martino, L., Salisbury, N. J. H., Brown, P., Kelly, G., Atkinson, R. A. & Conte, M. R., 1 Oct 2015, In: Biomolecular NMR Assignments. 9, 2, p. 337-340 4 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)174 Downloads (Pure) -
Disorder-To-Order Transition of MAGI-1 PDZ1 C-Terminal Extension upon Peptide Binding: Thermodynamic and Dynamic Insights
Ramírez, J., Recht, R., Charbonnier, S., Ennifar, E., Atkinson, R. A., Travé, G., Nominé, Y. & Kieffer, B., 17 Feb 2015, In: Biochemistry. 54, 6, p. 1327-37 11 p.Research output: Contribution to journal › Article › peer-review
10 Citations (Scopus) -
Synergic interplay of the La motif, RRM1 and the interdomain linker of LARP6 in the recognition of collagen mRNA expands the RNA binding repertoire of the La module
Martino, L., Pennell, S., Kelly, G., Busi, B., Brown, P., Atkinson, R. A., Salisbury, N. J. H., Ooi, Z.-H., See, K.-W., Smerdon, S. J., Alfano, C., Bui, T. T. T. & Conte, M. R., Jan 2015, In: Nucleic acids research. 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile47 Citations (Scopus)268 Downloads (Pure) -
2013
Insight into the HIV-1 Vif SOCS-box-ElonginBC interaction
Lu, Z., Bergeron, J. R. C., Atkinson, R. A., Schaller, T., Veselkov, D. A., Oregioni, A., Yang, Y., Matthews, S. J., Malim, M. H. & Sanderson, M. R., 13 Nov 2013, In: Open Biology. 3, 11Research output: Contribution to journal › Article › peer-review
Open Access8 Citations (Scopus) -
Mechanism and consequence of the autoactivation of p38α mitogen-activated protein kinase promoted by TAB1
De Nicola, G. F., Martin, E. D., Chaikuad, A., Bassi, R., Clark, J., Martino, L., Verma, S., Sicard, P., Tata, R., Atkinson, R. A., Knapp, S., Conte, M. R. & Marber, M. S., Oct 2013, In: NATURE STRUCTURAL AND MOLECULAR BIOLOGY. 20, 10, p. 1182-1190 9 p.Research output: Contribution to journal › Article › peer-review
92 Citations (Scopus) -
The asymmetric binding of PGC-1α to the ERRα and ERRγ nuclear receptor homodimers involves a similar recognition mechanism
Takacs, M., Petoukhov, M. V., Atkinson, R. A., Roblin, P., Ogi, F.-X., Demeler, B., Potier, N., Chebaro, Y., Dejaegere, A., Svergun, D. I., Moras, D. & Billas, I. M. L., 9 Jul 2013, In: PLoS ONE. 8, 7, 11 p., e67810.Research output: Contribution to journal › Article › peer-review
Open Access37 Citations (Scopus) -
2012
Conformational flexibility determines selectivity and antibacterial, antiplasmodial and anticancer potency of cationic α-helical peptides
Vermeer, L., Lan, Y., Abbate, V., Ruh, E., Bui, T., Wilkinson, L., Kanno, T., Jumagulova, E., Kozlowska, J., Patel, J., McIntyre, C. A., Yam, W., Siu, G., Atkinson, R. A., Lam, J., Bansal, S., Drake, A., Mitchell , G. H. & Mason, J., 5 Oct 2012, In: Journal of Biological Chemistry. 287, 41, p. 34120-34133 14 p.Research output: Contribution to journal › Article › peer-review
Open Access85 Citations (Scopus) -
Solution structure of RING finger-like domain of retinoblastoma-binding protein-6 (RBBP6) suggests it functions as a U-box
Kappo, M. A., Ab, E., Hassem, F., Atkinson, R. A., Faro, A., Muleya, V., Mulaudzi, T., Poole, J. O., McKenzie, J. M., Chibi, M., Moolman-Smook, J. C., Rees, D. J. G. & Pugh, D. J. R., 2 Mar 2012, In: Journal of Biological Chemistry. 287, 10, p. 7146-7158 13 p., N/A.Research output: Contribution to journal › Article › peer-review
13 Citations (Scopus) -
2011
The Structural and Dynamic Response of MAGI-1 PDZ1 with Noncanonical Domain Boundaries to the Binding of Human Papillomavirus E6
Charbonnier, S., Nominé, Y., Ramírez, J., Luck, K., Chapelle, A., Stote, R. H., Travé, G., Kieffer, B. & Atkinson, R. A., 11 Mar 2011, In: Journal of Molecular Biology. 406, 5, p. 745-63 19 p.Research output: Contribution to journal › Article › peer-review
43 Citations (Scopus)