King's College London

Research portal

Dr Anna Marie Davies

  1. Anti-IgE Antibodies

    Adams, R., Ceska, T. A., Davies, A. M., Henry, A. J., Liu, X., McDonnell, J. M., Sutton, B. J. & Westwood, M. K., 14 Dec 2017, Patent No. WO 2017/211928 A1, 8 Jun 2017, Priority date 10 Jun 2016, Priority No. 1610198.2

    Research output: Patent

  2. Allosteric mechanism of action of the therapeutic anti-IgE antibody omalizumab

    Davies, A. M., Allan, E. G., Keeble, A. H., Delgado, J., Cossins, B. P., Mitropoulou, A. N., Pang, M. O. Y., Ceska, T., Beavil, A. J., Craggs, G., Westwood, M., Henry, A. J., McDonnell, J. M. & Sutton, B. J., 16 Jun 2017, In : Journal of Biological Chemistry. 292, 24, p. 9975–9987

    Research output: Contribution to journalArticle

  3. Room temperature structure of human IgG4-Fc from crystals analysed in situ

    Davies, A. M., Rispens, T., Ooijevaar-de Heer, P., Aalberse, R. C. & Sutton, B. J., Jan 2017, In : Molecular Immunology. 81, p. 85-91 7 p.

    Research output: Contribution to journalArticle

  4. Antibodies and superantibodies in patients with chronic rhinosinusitis with nasal polyps

    Chen, J. B., James, L. K., Davies, A. M., Wu, Y. C. B., Rimmer, J., Lund, V. J., Chen, J. H., McDonnell, J. M., Chan, Y. C., Hutchins, G. H., Chang, T. W., Sutton, B. J., Kariyawasam, H. H. & Gould, H. J., 19 Sep 2016, In : Journal of Allergy and Clinical Immunology.

    Research output: Contribution to journalArticle

  5. Human IgG4: a structural perspective

    Davies, A. M. & Sutton, B. J., Nov 2015, In : Immunological Reviews. 268, 1, p. 139-159 21 p.

    Research output: Contribution to journalArticle

  6. Structure and dynamics of IgE-receptor interactions: FcεRI and CD23/FcεRII

    Sutton, B. J. & Davies, A. M., Nov 2015, In : Immunological Reviews. 268, 1, p. 222-235 14 p.

    Research output: Contribution to journalArticle

  7. Crystal structure of deglycosylated human IgG4-Fc

    Davies, A. M., Jefferis, R. & Sutton, B. J., Nov 2014, In : Molecular Immunology. 62, 1, p. 46-53 8 p.

    Research output: Contribution to journalArticle

  8. Structural Determinants of Unique Properties of Human IgG4-Fc

    Davies, A. M., Rispens, T., Ooijevaar-de Heer, P., Gould, H. J., Jefferis, R., Aalberse, R. C. & Sutton, B. J., 6 Feb 2014, In : Journal of Molecular Biology. 426, 3, p. 630-644 15 p.

    Research output: Contribution to journalArticle

  9. Human IgE against the major allergen Bet v 1: defining an epitope with limited cross-reactivity between different PR-10 family proteins

    Levin, M., Davies, A. M., Liljekvist, M., Carlsson, F., Gould, H. J., Sutton, B. J. & Ohlin, M., Feb 2014, In : Clinical and Experimental Allergy. 44, 2, p. 288-299 12 p.

    Research output: Contribution to journalArticle

  10. Dynamics of inter-heavy chain interactions in human IgG subclasses studied by kinetic Fab arm exchange

    Rispens, T., Davies, A. M., Ooijevaar-de Heer, P., Absalah, S., Bende, O., Sutton, B. J., Vidarsson, G. & Aalberse, R. C., 2014, In : Journal of Biological Chemistry. 289, 9, p. 6098-6109

    Research output: Contribution to journalArticle

  11. Crystal structure of the human IgG4 C(H)3 dimer reveals the role of Arg409 in the mechanism of Fab-arm exchange

    Davies, A. M., Rispens, T., den Bleker, T. H., McDonnell, J. M., Gould, H. J., Aalberse, R. C. & Sutton, B. J., May 2013, In : Molecular Immunology. 54, 1, p. 1-7 7 p.

    Research output: Contribution to journalArticle

  12. Conformational changes in IgE contribute to its uniquely slow dissociation rate from receptor FcɛRI

    Holdom, M. D., Davies, A. M., Nettleship, J. E., Bagby, S. C., Dhaliwal, B., Girardi, E., Hunt, J., Gould, H. J., Beavil, A. J., McDonnell, J. M., Owens, R. J. & Sutton, B. J., May 2011, In : NATURE STRUCTURAL AND MOLECULAR BIOLOGY. 18, 5, p. 571 - 576 6 p.

    Research output: Contribution to journalArticle

  13. Synthesis of the C19 methyl ether of aspercyclide A via germyl-Stille macrocyclisation and ELISA evaluation of both enantiomers following optical resolution

    Carr, J. L., Sejberg, J. J. P., Saab, F., Holdom, M. D., Davies, A. M., White, A. J. P., Leatherbarrow, R. J., Beavil, A. J., Sutton, B. J., Lindell, S. D. & Spivey, A. C., 2011, In : ORGANIC AND BIOMOLECULAR CHEMISTRY. 9, 19, p. 6814-6824

    Research output: Contribution to journalArticle

  14. Structure and substrate specificity of acetyltransferase ACIAD1637 from Acinetobacter baylyi ADP1

    Davies, A. M., Tata, R., Snape, A., Sutton, B. J. & Brown, P. R., Apr 2009, In : Biochimie. 91, 4, p. 484 - 489

    Research output: Contribution to journalArticle

  15. The crystal structure of rabbit IgG-Fc

    Girardi, E., Holdom, M. D., Davies, A. M., Sutton, B. J. & Beavil, A. J., 1 Jan 2009, In : Biochemical Journal. 417, 1, p. 77 - 83 7 p.

    Research output: Contribution to journalArticle

  16. Structure of a putative acetyltransferase (PA1377) from Pseudomonas aeruginosa

    Davies, A. M., Tata, R., Chauviac, F. X., Sutton, B. J. & Brown, P. R., 5 Apr 2008, In : Acta Crystallographica Section F-Structural Biology And Crystallization Communications. 64, 5, p. 338 - 342

    Research output: Contribution to journalArticle

  17. Crystal structure of a putative phosphinothricin acetyltransferase (PA4866) from Pseudomonas aeruginosa PAC1

    Davies, A. M., Tata, R., Agha, R., Sutton, B. J. & Brown, P., 15 Nov 2005, In : Proteins. 61, 3, p. 677 - 679 3 p.

    Research output: Contribution to journalArticle

  18. Effect of pH on the active site of an Arg121Cys mutant of the metallo-beta-lactamase from Bacillus cereus: implications for the enzyme mechanism

    Davies, A. M., Rasia, R. M., Vila, A. J., Sutton, B. J. & Fabiane, S. M., 29 Mar 2005, In : Biochemistry. 44, 12, p. 4841 - 4849

    Research output: Contribution to journalArticle

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