Search results

• 2005

  DNA topoisomerase II in therapy-related acute promyelocytic leukemia

  Mistry, A. R., Felix, C. A., Whitmarsh, R. J., Mason, A., Reiter, A., Cassinat, B., Parry, A., Walz, C., Wiemels, J. L., Segal, M. R., Ades, L., Blair, I. A., Osheroff, N., Peniket, A. J., Lafage-Pochitaloff, M., Cross, N. C. P., Chomienne, C., Solomon, E., Fenaux, P. & Grimwade, D., 14 Apr 2005, In: New England Journal of Medicine. 352, 15, p. 1529 - 1538 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Therapeutic Procedure 100%
  • Acute Promyelocytic Leukemia 100%
  • DNA Topoisomerase (ATP Hydrolysing) 100%
  • Granulocyte 33%
  • Poison 33%
  259 Citations (Scopus)
• 2004

  Genomic breakpoint cloning and a functional assay of DNA topoisomerase II cleavage reveal translocation mechanism underlying formation of t(15;17) in therapy-related acute promyelocytic leukaemia

  Mistry, A. R., Felix, C. A., Whitmarsh, R., Mason, A., Reiter, A., Cassinat, B., Parry, A., Walz, C., Wiemels, J. L., Segal, M., Ades, L., Blair, I. A., Osheroff, N., Littlewood, T. J., Lafage-Pochitaloff, M., Cross, N. C. P., Chomienne, C., Solomon, E., Fenaux, P. & Grimwade, D., 2004, In: British Journal of Haematology. 125, p. 67 - 67 1 p.

  Research output: Contribution to journal › Meeting abstract
• 2003

  Mitoxantrone induces DNA topoisomerase II cleavage at translocation breakpoint hotspot in PML gene in acute promyelocytic leukemia.

  Mistry, A. R., Felix, C. A., Whitmarsh, R., Mason, A., Reiter, A., Cassinat, B., Parry, A., Walz, C., Ades, L., Blair, I. A., Osheroff, N., Littlewood, T. J., Lafage-Pochitaloff, M., Cross, N. C. P., Chomienne, C., Solomon, E., Fenaux, P. & Grimwade, D., 2003, In: Blood. 102, 11, p. 215A - 215A

  Research output: Contribution to journal › Meeting abstract