Anne-Maj Samuelsson Apel

Anne-Maj Samuelsson Apel

Dr

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Personal profile

Research interests

I am interested in understanding the mechanisms by which early events during fetal and neonatal life may lead to long-term consequences to cardiovascular health. My primary research interests lie in the field of sympathetic mediated hypertension, to identify novel pathways and intervention during pregnancy and early life that may reverse/ameliorate heightened blood pressure in the offspring born to diet induced obese dams. Future prospects include the relevance to man by studying the relationship between maternal obeisty and childhood autonomic dysfunction in existing birth cohorts. 

Future directions: To study the role of neuroinflammation in the pathogenesis of hypertension. I will employ cutting-edge techniques, including bioelectronics (collaborator, Prof P. Olofsson, Ki, Sweden), patch clamp technique, MRI and pharmacogenetics for selective activation or inhibition of microglial and neuronal networks (collaborator, Prof. P Gressens, KCL, UK). Translational studies involving human blood pressure data, behavioural and urine samples will provide early markers of sympathetic hyperactivity and immune dysfunction (Prof Lucilla Poston, Division of Women’s Health, KCL, UK). 

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

Postgraduate Diploma, King's College London

Award Date: 1 Jan 2010

Doctor of Science, Effects of prenatal IL-6 exposure and hyperinsulinemia on neuroendocrine regulation, University of Gothenburg

Award Date: 1 Jan 2005

Master of Natural Science, University of Gothenburg

Award Date: 1 Jan 2000

External positions

Project Coordinator

1 Jan 201731 Mar 2017

Keywords

  • RA0421 Public health. Hygiene. Preventive Medicine
  • RG Gynecology and obstetrics
  • R Medicine (General)

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