King's College London

Research portal

Dr Anne Umpleby

  1. Effects of recombinant human IGF-I/IGF-binding protein-3 complex on glucose and glycerol metabolism in type 1 diabetes

    Saukkonen, T., Shojaee-Moradie, F., Williams, R. M., Amin, R., Yuen, K. C., Watts, A., Acerini, C. L., Umpleby, A. M. & Dunger, D. B., Aug 2006, In: Diabetes. 55, 8, p. 2365 - 2370 6 p.

    Research output: Contribution to journalArticlepeer-review

  2. Acute regulation of plasma leptin by isoprenaline in lean and obese fasted subjects

    Baynes, K. C. R., Nicholas, M. D., Shojaee-Moradie, F., Umpleby, A. M. & Giannoulis, M. G., Jul 2006, In: DIABETES OBESITY AND METABOLISM. 8, 4, p. 412 - 418 7 p.

    Research output: Contribution to journalArticlepeer-review

  3. In treatment-naive and antiretroviral-treated subjects with HIV, reduced plasma adiponectin is associated with a reduced fractional clearance rate of VLDL, IDL and LDL apolipoprotein B-100

    Das, S., Shahmanesh, M., Stolinski, M., Shojaee-Moradie, F., Jefferson, W., Jackson, N. C., Cobbold, M., Nightingale, P. & Umpleby, A. M., Mar 2006, In: Diabetologia. 49, 3, p. 538 - 542 5 p.

    Research output: Contribution to journalArticlepeer-review

  4. Low-density lipoprotein apolipoprotein B100 turnover in hypopituitary patients with GH deficiency: a stable isotope study

    Christ, E. R., Cummings, M. H., Stolinski, M., Jackson, N., Lumb, P. J., Wierzbicki, A. S., Sonksen, P. H., Russell-Jones, D. L. & Umpleby, A. M., Mar 2006, In: European Journal of Endocrinology. 154, 3, p. 459 - 466 8 p.

    Research output: Contribution to journalArticlepeer-review

  5. Contrasting insulin sensitivity of endogenous glucose production rate in subjects with hepatocyte nuclear factor-1 beta and -1 alpha mutations

    Brackenridge, A., Pearson, E. R., Shojaee-Moradie, F., Hattersley, A. T., Russell-Jones, D. & Umpleby, A. M., Feb 2006, In: Diabetes. 55, 2, p. 405 - 411 7 p.

    Research output: Contribution to journalArticlepeer-review

  6. Effects of high-dose growth hormone on glucose and glycerol metabolism at rest and during exercise in endurance-trained athletes

    Healy, M. L., Gibney, J., Pentecost, C., Croos, P., Russell-Jones, D. L., Sonken, P. H. & Umpleby, A. M., Jan 2006, In: Journal of Clinical Endocrinology and Metabolism. 91, 1, p. 320 - 327 8 p.

    Research output: Contribution to journalArticlepeer-review

  7. GH secretion in acute exercise may result in post-exercise lipolysis

    Wee, J., Charlton, C., Simpson, H., Jackson, N. C., Shojaee-Moradie, F., Stolinski, M., Pentecost, C. & Umpleby, A. M., Dec 2005, In: GROWTH HORMONE AND IGF RESEARCH. 15, 6, p. 397 - 404 8 p.

    Research output: Contribution to journalArticlepeer-review

  8. Growth hormone and testosterone interact positively to enhance protein and energy metabolism in hypopituitary men

    Gibney, J., Wolthers, T., Johannsson, G., Umpleby, A. M. & Ho, K. K. Y., Aug 2005, In: AMERICAN JOURNAL OF PHYSIOLOGY: ENDOCRINOLOGY AND METABOLISM. 289, 2, p. E266 - E271

    Research output: Contribution to journalArticlepeer-review

  9. Comparison of the effects on glucose and lipid metabolism of equipotent doses of insulin detemir and NPH insulin with a 16-h euglycaemic clamp

    Hordern, S. V. M., Wright, J. E., Umpleby, A. M., Shojaee-Moradie, F., Amiss, J. & Russell-Jones, D. L., Mar 2005, In: Diabetologia. 48, 3, p. 420 - 426 7 p.

    Research output: Contribution to journalArticlepeer-review

  10. Antiretroviral treatment reduces very-low-density lipoprotein and intermediate-density lipoprotein apolipoprotein B fractional catabolic rate in human immunodeficiency virus-infected patients with mild dyslipidemia

    Shahmanesh, M., Das, S., Stolinski, M., Shojaee-Moradie, F., Jackson, N. C., Jefferson, W., Cramb, R., Nightingale, P. & Umpleby, A. M., Feb 2005, In: Journal of Clinical Endocrinology and Metabolism. 90, 2, p. 755 - 760 6 p.

    Research output: Contribution to journalArticlepeer-review

  11. Low density lipoprotein apolipoprotein B metabolism in treatment-naive HIV patients and patients on antiretroviral therapy

    Umpleby, A. M., Das, S., Stolinski, M., Shojaee-Moradie, F., Jackson, N. C., Jefferson, W., Crabtree, N., Nightingale, P. & Shahmanesh, M., 2005, In: ANTIVIRAL THERAPY. 10, 5, p. 663 - 670 8 p.

    Research output: Contribution to journalArticlepeer-review

  12. The effect of insulin dose and level of glycaemia on catabolism in critically ill patients

    Whyte, M., Jackson, N., Shojaee-Moradie, F., Sharma, R., Treacher, D., Beale, R., Jones, R. H. & Umpleby, A. M., 2005, In: Diabetologia. 48, p. 595 1 p.

    Research output: Contribution to journalMeeting abstract

  13. Dose-dependent effects of recombinant human insulin-like growth factor (IGF)-I/IGF binding protein-3 complex on overnight growth hormone secretion and insulin sensitivity in type 1 diabetes

    Saukkonen, T., Amin, R., Williams, R. M., Fox, C., Yuen, K. C., White, M. A., Umpleby, A. M., Acerini, C. L. & Dunger, D. B., Sep 2004, In: Journal of Clinical Endocrinology and Metabolism. 89, 9, p. 4634 - 4641 8 p.

    Research output: Contribution to journalArticlepeer-review

  14. A family with severe insulin resistance and diabetes due to a mutation in AKT2

    George, S., Rochford, J. J., Wolfrum, C., Gray, S. L., Schinner, S., Wilson, J. C., Soos, M. A., Murgatroyd, P. R., Williams, R. M., Acerini, C. L., Dunger, D. B., Barford, D., Umpleby, A. M., Wareham, N. J., Davies, H. A., Schafer, A. J., Stoffel, M., O'Rahilly, S. & Barroso, I., 28 May 2004, In: Science. 304, 5675, p. 1325 - 1328 4 p.

    Research output: Contribution to journalArticlepeer-review

  15. Effects of growth hormone (GH) replacement therapy on low-density lipoprotein apolipoprotein b100 kinetics in adult patients with GH deficiency: A stable isotope study

    Christ, E. R., Cummings, M. H., Jackson, N., Stolinski, M., Lumb, P. J., Wierzbicki, A. S., Sonksen, P. H., Russell-Jones, D. L. & Umpleby, A. M., Apr 2004, In: Journal of Clinical Endocrinology and Metabolism. 89, 4, p. 1801 - 1807 7 p.

    Research output: Contribution to journalArticlepeer-review

  16. The effect of a six-month exercise program on very low-density lipoprotein apolipoprotein B secretion in type 2 diabetes

    Alam, S., Stolinski, M., Pentecost, C., Boroujerdi, M. A., Jones, R. H., Sonksen, P. H. & Umpleby, A. M., Feb 2004, In: Journal of Clinical Endocrinology and Metabolism. 89, 2, p. 688 - 694 7 p.

    Research output: Contribution to journalArticlepeer-review

  17. Combined growth hormone/insulin-like growth factor I in addition to glutamine-supplemented TPN results in net protein anabolism in critical illness

    Carroll, P. V., Jackson, N. C., Russell-Jones, D. L., Treacher, D. F., Sonksen, P. H. S. & Umpleby, A. M., Jan 2004, In: AMERICAN JOURNAL OF PHYSIOLOGY: ENDOCRINOLOGY AND METABOLISM. 286, 1, p. E151 - E157

    Research output: Contribution to journalArticlepeer-review

  18. Insulin-like growth factor I has a direct effect on glucose and protein metabolism, but no effect on lipid metabolism in type 1 diabetes

    Simpson, H. L., Jackson, N. C., Shojaee-Moradie, F., Jones, R. H., Russell-Jones, D. L., Sonksen, P. H., Dunger, D. B. & Umpleby, A. M., Jan 2004, In: Journal of Clinical Endocrinology and Metabolism. 89, 1, p. 425 - 432 8 p.

    Research output: Contribution to journalArticlepeer-review

  19. The effect of long term exercise on intrahepatic lipid and the insulin sensitivity of glucose and fatty acid metabolism in sedentary male subjects

    Shojaee-Moradie, F., Baynes, K., Pentecost, C., Bell, J. D., Thomas, E. L., Jackson, N. C., Jackson, N. C., Stolinski, M., Whyte, M., Jones, R. H. & Umpleby, A. M., 2004, In: Diabetologia. 47, p. 678 1 p.

    Research output: Contribution to journalMeeting abstract

  20. High dose growth hormone exerts an anabolic effect at rest and during exercise in endurance-trained athletes

    Healy, M. L., Gibney, J., Russell-Jones, D. L., Pentecost, C., Croos, P., Sonksen, P. H. & Umpleby, A. M., Nov 2003, In: Journal of Clinical Endocrinology and Metabolism. 88, 11, p. 5221 - 5226 6 p.

    Research output: Contribution to journalArticlepeer-review

  21. The effects of a specific growth hormone antagonist on overnight insulin requirements and insulin sensitivity in young adults with Type 1 diabetes mellitus

    Williams, R. M., Amin, R., Shojaee-Moradie, F., Umpleby, A. M., Acerini, C. L. & Dunger, D. B., 1 Sep 2003, In: Diabetologia. 46, 9, p. 1203 - 1210 8 p.

    Research output: Contribution to journalArticlepeer-review

  22. Effect of growth hormone (GH) on glycerol and free fatty acid metabolism during exhaustive exercise in GH-deficient adults

    Gibney, J., Healy, M. L., Stolinski, M., Bowes, S. B., Pentecost, C., Breen, L., McMillan, C., Russell-Jones, D. L., Sonksen, P. H. & Umpleby, A. M., 1 Apr 2003, In: Journal of Clinical Endocrinology and Metabolism. 88, 4, p. 1792 - 1797 6 p.

    Research output: Contribution to journalArticlepeer-review

  23. Human metabolic syndrome resulting from dominant-negative mutations in the nuclear receptor peroxisome proliferator-activated receptor-gamma

    Savage, D. B., Tan, G. D., Acerini, C. L., Jebb, S. A., Agostini, M., Gurnell, M., Williams, R. L., Umpleby, A. M., Thomas, E. L., Bell, J. D., Dixon, A. K., Dunne, F., Boiani, R., Cinti, S., Vidal-Puig, A., Karpe, F., Chatterjee, V. K. K. & Rahilly, S., 1 Apr 2003, In: Diabetes. 52, 4, p. 910 - 917 8 p.

    Research output: Contribution to journalArticlepeer-review

  24. The role of hepatic portal glucose sensing in modulating responses to hypoglycaemia in man

    Smith, D., Pernet, A., Reid, H., Bingham, E., Rosenthal, J. M., Macdonald, I. A., Umpleby, A. M. & Amiel, S. A., Oct 2002, In: Diabetologia. 45, 10, p. 1416-1424 9 p.

    Research output: Contribution to journalArticlepeer-review

  25. Effect of IGF-I therapy on VLDL apolipoprotein B100 metabolism in type 1 diabetes mellitus

    Christ, E. R., Carroll, P. V., Albany, E., Umpleby, A. M., Lumb, P. J., Wierzbicki, A. S., Sonksen, P. H. & Russell-Jones, D. L., 2002, In: AMERICAN JOURNAL OF PHYSIOLOGY: ENDOCRINOLOGY AND METABOLISM. 282, 5, p. E1154 - E1162

    Research output: Contribution to journalArticlepeer-review

  26. Glutamine supplementation and GHAGF-I treatment in critically ill patients: Effects on glutamine metabolism and protein balance

    Umpleby, A. M., Carroll, P. V., Russell-Jones, D. L., Treacher, D. F. & Jackson, N. C., 2002, In: Nutrition. 18, 2, p. 127 - 129 3 p.

    Research output: Contribution to journalArticlepeer-review

  27. Partitioning glucose distribution/transport, disposal, and endogenous production during IVGTT

    Hovorka, R., Shojaee-Moradie, F., Carroll, P. V., Chassin, L. J., Gowrie, I. J., Jackson, N. C., Tudor, R. S., Umpleby, A. M. & Jones, R. H., 2002, In: AMERICAN JOURNAL OF PHYSIOLOGY: ENDOCRINOLOGY AND METABOLISM. 282, 5, p. E992 - E1007

    Research output: Contribution to journalArticlepeer-review

  28. Normal VLDL metabolism despite altered lipoprotein composition in type 1 diabetes mellitus

    Christ, E. R., Carroll, P. V., Albany, E., Umpleby, A. M., Lumb, P. J., Wierzbicki, A. S., Simpson, H. L., Sonksen, P. H. & Russell-Jones, D. L., 2001, In: Clinical endocrinology. 55, 6, p. 777 - 787 11 p.

    Research output: Contribution to journalArticlepeer-review

  29. Partitioning glucose transport/distribution and disposal during euglycaemic clamp

    Shojaee-Moradie, F., Carroll, P. V., Chassin, L. J., Gowrie, I. J., Jackson, N. C., Jones, R. H., Tudor, R. S., Umpleby, A. M. & Hovorka, R., 2001, In: Diabetologia. 44, p. A206 - A206

    Research output: Contribution to journalMeeting abstract

  30. Temporal changes in insulin sensitivity following the development of acute liver failure secondary to acetaminophen

    Clark, S. J., Shojaee-Moradie, F., Croos, P., Seed, P. T., Umpleby, A. M., Wendon, J. A. & Miell, J., 2001, In: Hepatology. 34, 1, p. 109 - 115 7 p.

    Research output: Contribution to journalArticlepeer-review

  31. IGF-I treatment in adults with type 1 diabetes - Effects on glucose and protein metabolism in the fasting state and during a hyperinsulinemic-euglycemic amino acid clamp

    Carroll, P. V., Christ, E. R., Umpleby, A. M., Gowrie, I., Jackson, N., Bowes, S. B., Hovorka, R., Croos, P., Sonksen, P. H. & Russell-Jones, D. L., May 2000, In: Diabetes. 49, 5, p. 789 - 796 8 p.

    Research output: Contribution to journalArticlepeer-review

  32. Effects of glutamine supplementation, GH, and IGF-I on glutamine metabolism in critically ill patients

    Jackson, N. C., Carroll, P. V., Russell-Jones, D. L., Sonksen, P. H., Treacher, D. F. & Umpleby, A. M., Feb 2000, In: AMERICAN JOURNAL OF PHYSIOLOGY: ENDOCRINOLOGY AND METABOLISM. 278, 2, p. E226 - E233

    Research output: Contribution to journalArticlepeer-review

  33. Low dose IGF-I therapy improves insulin sensitivity but has no effect on VLDL apoB kinetics in type 1 diabetes.

    Christ, E. R., Carroll, P. V., Umpleby, A. M., Albany, E., Lumb, P. J., Wierzbicki, A. S., Sonksen, P. H. & Jones, D. L. R., 2000, In: Diabetologia. 43, p. A176 - A176

    Research output: Contribution to journalMeeting abstract

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