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Research interests

My research topic is fibre type specialisation of skeletal muscle, mainly investigated by immunostaining, morphometric and electrophoretic methods.  Initially, motor unit development and vertebrate jaw muscle specialisation were the main focus of my work, but this was followed by a programme of studies with various research groups in the UK, Italy, Portugal and Israel examining the diversity, growth and development of fish muscle, especially in species of interest for aquaculture (e.g. Silva et al, 2008).  More recently I have collaborated in studies on prenatal nutritional programming of adult muscle characteristics (with research groups both at KCL and elsewhere).  Prenatal programming is known to be an important factor in human health, and is accessible to investigation with a number of animal models (Costello et al, 2008; Shelley et al, 2009; Markham et al, 2009).  Current research projects are concerned with human muscle both in dysfunctional conditions (e.g. in patients with chronic respiratory disease, following spinal cord injury, or undergoing intensive care stays – this in collaboration with clinicians and scientists at KCL and elsewhere) (e.g. Duffell et al, 2009; Puthucheary et al, 2013) and the significance of fibre type composition in masseter muscle for the development of malocclusion (also a collaborative project, with maxillofacial surgeons from the University of Lille, France, and orthodontists at KCL andTemple University, Pennsylvania) (Raoul et al, 2011; Sciote et al, 2012).

Biographical details

PhD in Physiology from the University of London (1980), followed by post-doctoral work in veterinary faculties in Switzerland (University of Zurich) and Italy, and later in Physiology departments in Glasgow and Bristol.  Appointed lecturer in Physiology at UMDS (London) (1989), and later (2007, after the merger with King’s College London) Senior Lecturer.  Ordinary Member of the Physiological Society since 1991, and referee for a variety of biomedical science journals.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 2 - Zero Hunger
  • SDG 3 - Good Health and Well-being
  • SDG 14 - Life Below Water

Education/Academic qualification

Doctor of Philosophy, Immunohistochemica; & biochemical studies of the specialisation of muscle fibre types., University of London

Award Date: 1 Jan 1980

Bachelor of Arts, University of Oxford

Award Date: 1 Jan 1974

Keywords

  • QP Physiology

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