Anthony Cheung

2023

B cell profiles, antibody repertoire and reactivity reveal dysregulated responses with autoimmune features in melanoma

Crescioli, S., Correa, I., Ng, J., Willsmore, Z. N., Laddach, R., Chenoweth, A., Chauhan, J., Di Meo, A., Stewart, A., Kalliolia, E., Alberts, E., Adams, R., Harris, R. J., Mele, S., Pellizzari, G., Black, A. B. M., Bax, H. J., Cheung, A., Nakamura, M., Hoffmann, R. M., & 23 othersTerranova-Barberio, M., Ali, N., Batruch, I., Soosaipillai, A., Prassas, I., Ulndreaj, A., Chatanaka, M. K., Nuamah, R., Kannambath, S., Dhami, P., Geh, J. L. C., MacKenzie Ross, A. D., Healy, C., Grigoriadis, A., Kipling, D., Karagiannis, P., Dunn-Walters, D. K., Diamandis, E. P., Tsoka, S., Spicer, J., Lacy, K. E., Fraternali, F. & Karagiannis, S. N., 8 Jun 2023, In: Nature Communications. 14, 1, 3378.

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Target Antigen Attributes and Their Contributions to Clinically Approved Antibody-Drug Conjugates (ADCs) in Haematopoietic and Solid Cancers

Esapa, B., Jiang, J., Cheung, A., Chenoweth, A., Thurston, D. E. & Karagiannis, S. N., 19 Mar 2023, In: Cancers. 15, 6, 37 p., 1845.

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5 Citations (Scopus)

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2022

Enriched circulating and tumor-resident TGF-β+ regulatory B cells in patients with melanoma promote FOXP3+ Tregs

Harris, R. J., Willsmore, Z., Laddach, R., Crescioli, S., Chauhan, J., Cheung, A., Black, A., Geh, J. L. C., MacKenzie Ross, A. D., Healy, C., Tsoka, S., Spicer, J., Lacy, K. E. & Karagiannis, S. N., 28 Jul 2022, In: OncoImmunology. 11, 1, p. 2104426 2104426.

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4 Citations (Scopus)

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2021

B Cells in Patients With Melanoma: Implications for Treatment With Checkpoint Inhibitor Antibodies

Willsmore, Z. N., Harris, R. J., Crescioli, S., Hussein, K., Kakkassery, H., Thapa, D., Cheung, A., Chauhan, J., Bax, H. J., Chenoweth, A., Laddach, R., Osborn, G., McCraw, A., Hoffmann, R. M., Nakamura, M., Geh, J. L., MacKenzie-Ross, A., Healy, C., Tsoka, S., Spicer, J. F., & 4 othersPapa, S., Barber, L., Lacy, K. E. & Karagiannis, S. N., 25 Jan 2021, In: Frontiers in Immunology. 11, 622442.

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32 Citations (Scopus)

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Immunotherapy using IgE or CAR T cells for cancers expressing the tumor antigen SLC3A2

Pellizzari, G., Martinez, O., Crescioli, S., Page, R., Di Meo, A., Mele, S., Chiaruttini, G., Hoinka, J., Batruch, I., Prassas, I., Grandits, M., López-Abente, J., Bugallo-Blanco, E., Ward, M., Bax, H. J., French, E., Cheung, A., Lombardi, S., Figini, M., Lacy, K. E., & 5 othersDiamandis, E. P., Josephs, D. H., Spicer, J., Papa, S. & Karagiannis, S. N., 11 Jun 2021, In: Journal for ImmunoTherapy of Cancer. 9, 6, e002140.

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9 Citations (Scopus)

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Innate stimulation of B cells ex vivo enhances antibody secretion and identifies tumour-reactive antibodies from cancer patients

Karagiannis, P., Correa, I., Chauhan, J., Cheung, A., Dominguez-Rodriguez, D., Terranova Barberio, M., Harris, R. J., Crescioli, S., Spicer, J., Bokemeyer, C., Lacy, K. E. & Karagiannis, S. N., 5 Dec 2021, In: Clin Exp Immunol.

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3 Citations (Scopus)

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Tumor-Infiltrating B Lymphocyte Profiling Identifies IgG-Biased, Clonally Expanded Prognostic Phenotypes In Triple-Negative Breast Cancer

Harris, R. J., Cheung, A., Ng, J. C. F., Laddach, R., Chenoweth, A. M., Crescioli, S., Fittall, M., Dominguez-Rodriguez, D., Roberts, J., Levi, D., Liu, F., Alberts, E., Quist, J., Santaolalla, A., Pinder, S. E., Gillett, C., Hammar, N., Irshad, S., van Hemelrijck, M., Dunn-Walters, D. K., & 7 othersFraternali, F., Spicer, J. F., Lacy, K. E., Tsoka, S., Grigoriadis, A., Tutt, A. N. J. & Karagiannis, S. N., 15 Aug 2021, In: Cancer Research. 81, 16, p. 4290-4304 15 p.

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28 Citations (Scopus)

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2020

A Novel Antibody-Drug Conjugate (ADC) Delivering a DNA Mono-Alkylating Payload to Chondroitin Sulfate Proteoglycan (CSPG4)-Expressing Melanoma

Hoffmann, R. M., Crescioli, S., Mele, S., Sachouli, E., Cheung, A., Chui, C. K., Andriollo, P., Jackson, P. J. M., Lacy, K. E., Spicer, J. F., Thurston, D. E. & Karagiannis, S. N., 22 Apr 2020, In: Cancers. 12, 4, 1029.

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19 Citations (Scopus)

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Rapid conjugation of antibodies to toxins to select candidates for the development of anticancer Antibody-Drug Conjugates (ADCs)

Hoffmann, R. M., Mele, S., Cheung, A., Larcombe-Young, D., Bucaite, G., Sachouli, E., Zlatareva, I., Morad, H. O. J., Marlow, R., McDonnell, J. M., Figini, M., Lacy, K. E., Tutt, A. J. N., Spicer, J. F., Thurston, D. E., Karagiannis, S. N. & Crescioli, S., 1 Jun 2020, In: Scientific Reports. 10, 1, p. 8869 8869.

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7 Citations (Scopus)

42 Downloads (Pure)

2019

Integrin-mediated macrophage adhesion promotes lymphovascular dissemination in breast cancer

Evans, R., Flores-Borja, F., Nassiri, S., Miranda, E., Lawler, K., Grigoriadis, A., Monypenny, J., Gillett, C., Owen, J., Gordon, P., Male, V., Cheung, A., Noor, F., Barber, P., Marlow, R., Francesch-Domenech, E., Fruhwirth, G., Squadrito, M., Vojnovic, B., Tutt, A., & 3 othersFesty, F., De Palma, M. & Ng, T., 14 May 2019, In: Cell Reports. 27, 7, p. 1967-1978.e4

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35 Citations (Scopus)

216 Downloads (Pure)

2018

ALIX Regulates Tumor-Mediated Immunosuppression by Controlling EGFR Activity and PD-L1 Presentation

Monypenny, J., Milewicz, H., Flores-Borja, F., Weitsman, G., Cheung, A., Chowdhury, R., Burgoyne, T., Arulappu, A., Lawler, K., Barber, P. R., Vicencio, J. M., Keppler, M., Wulaningsih, W., Davidson, S. M., Fraternali, F., Woodman, N., Turmaine, M., Gillett, C., Franz, D., Quezada, S. A., & 6 othersFutter, C. E., Von Kriegsheim, A., Kolch, W., Vojnovic, B., Carlton, J. G. & Ng, T., 17 Jul 2018, In: Cell Reports. 24, 3, p. 630-641 12 p.

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89 Citations (Scopus)

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Antibody structure and engineering considerations for the design and function of Antibody Drug Conjugates (ADCs)

Hoffmann, R. M., Coumbe, B. G. T., Josephs, D. H., Mele, S., Ilieva, K. M., Cheung, A., Tutt, A. N., Spicer, J. F., Thurston, D. E., Crescioli, S. & Karagiannis, S. N., 2018, In: OncoImmunology. 7, 3, p. e1395127-e1395127-11 12 p., e1395127.

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107 Citations (Scopus)

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Chondroitin sulfate proteoglycan 4 and its potential as an antibody immunotherapy target across different tumor types

Ilieva, K. M., Cheung, A., Mele, S., Chiaruttini, G., Crescioli, S., Griffin, M., Nakamura, M., Spicer, J. F., Tsoka, S., Lacy, K. E., Tutt, A. N. J. & Karagiannis, S. N., 10 Jan 2018, In: Frontiers in Immunology. 8, JAN, p. 1911 15 p., 1911.

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76 Citations (Scopus)

315 Downloads (Pure)

2017

Anti-folate receptor-α IgE but not IgG recruits macrophages to attack tumors via TNFa/MCP-1 signaling

Josephs, D. H., Bax, H. J., Dodev, T., Georgouli, M., Nakamura, M., Pellizzari, G., Saul, L., Karagiannis, P., Cheung, A., Herraiz, C., Ilieva, K. M., Correa, I., Fittall, M., Crescioli, S., Gazinska, P., Woodman, N., Mele, S., Chiaruttini, G., Gilbert, A. E., Koers, A., & 21 othersBracher, M., Selkirk, C., Lentfer, H., Barton, C., Lever, E., Muirhead, G., Tsoka, S., Canevari, S., Figini, M., Montes, A., Downes, N., Dombrowicz, D., Corrigan, C. J., Beavil, A. J., Nestle, F. O., Jones, P. S., Gould, H. J., Sanz-Moreno, V., Blower, P. J., Spicer, J. F. & Karagiannis, S. N., 31 Mar 2017, In: Cancer Research. 77, 5, p. 1127-1141 15 p.

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