Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Ligand-induced conformational changes in the β1-adrenergic receptor revealed by hydrogen-deuterium exchange mass spectrometry
Toporowska, J., Kapoor, P., Musgaard, M., Gherbi, K., Sengmany, K., Qu, F., Soave, M., Yen, H. Y., Hansen, K., Jazayeri, A., Hopper, J. T. S. & Politis, A., 18 Oct 2024, (E-pub ahead of print) In: Nature communications. 15, 1, 8993.Research output: Contribution to journal › Article › peer-review
Open AccessFile21 Citations (Scopus)6 Downloads (Pure) -
Integrating Hydrogen Deuterium Exchange-Mass Spectrometry with Molecular Simulations Enables Quantification of the Conformational Populations of the Sugar Transporter XylE
Jia, R., Bradshaw, R. T., Calvaresi, V. & Politis, A., 28 Mar 2023, In: Journal of the American Chemical Society. 145, 14, p. 7768-7779 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Citations (Scopus)13 Downloads (Pure) -
Structural dynamics in the evolution of SARS-CoV-2 spike glycoprotein
Reading, E., Calvaresi, V., Hammerschmid, D., Toporowska, J., Doores, K., Bradshaw, R. T., Malim, M., Politis, A., Roustan, C., Wrobel, A. G., Gamblin, S. J., Benton, D. J. & Parsons, R. B., 15 Feb 2023, (Accepted/In press) In: Nature Communications.Research output: Contribution to journal › Article › peer-review
Open AccessFile64 Downloads (Pure) -
A neutralizing epitope on the SD1 domain of SARS-CoV-2 Spike targeted following infection and vaccination.
Seow, J., Khan, H., Rosa, A., Calvaresi, V., Graham, C., Pickering, S., Pye, V. E., Cronin, N., Huettner, I., Malim, M., Politis, A., Cherepanov, P. & Doores, K., 26 Jul 2022, (Accepted/In press) In: Cell Reports.Research output: Contribution to journal › Article › peer-review
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Cold Denaturation of Proteins in the Absence of Solvent: Implications for Protein Storage**
Norgate, E. L., Upton, R., Hansen, K., Bellina, B., Brookes, C., Politis, A. & Barran, P. E., 20 Jun 2022, In: Angewandte Chemie - International Edition. 61, 25, e202115047.Research output: Contribution to journal › Article › peer-review
Open Access19 Citations (Scopus)
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Mapping membrane protein dynamics in time and space with mass spectrometry
Politis, A. (Primary Investigator)
EPSRC Engineering and Physical Sciences Research Council
17/01/2022 → 16/01/2027
Project: Research
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A cryo-electron microscope for structural biology (including single-particle and tomography) at KCL.
Conte, M. (Primary Investigator), Atherton, J. (Co-Investigator), Beavil, A. (Co-Investigator), Bergeron, J. (Co-Investigator), Booth, P. (Co-Investigator), Burrone, J. (Co-Investigator), Carlton, J. (Co-Investigator), De Nicola, G. (Co-Investigator), Ehler, E. (Co-Investigator), Fleck, R. (Co-Investigator), Fraternali, F. (Co-Investigator), Garnett, J. (Co-Investigator), Gautel, M. (Co-Investigator), Isaacson, R. (Co-Investigator), Kampourakis, T. (Co-Investigator), Malim, M. (Co-Investigator), McDonnell, J. (Co-Investigator), Neil, S. (Co-Investigator), Odendall, C. (Co-Investigator), Pfuhl, M. (Co-Investigator), Politis, A. (Co-Investigator), Steiner, R. (Co-Investigator) & Sutton, B. (Co-Investigator)
BBSRC Biotechnology and Biological Sciences Research Council
1/08/2022 → 31/07/2023
Project: Research
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SECMALS: A dual DLS and SEC-MALS instrumentation to characterize the oligomerization of protein samples for structural biology, mechanistic biology, and therapeutic development
Bergeron, J. (Primary Investigator), Atherton, J. (Co-Investigator), Beavil, A. (Co-Investigator), Booth, P. (Co-Investigator), Conte, M. (Co-Investigator), Garnett, J. (Co-Investigator), Isaacson, R. (Co-Investigator), Malim, M. (Co-Investigator), Muller, M. (Co-Investigator), Pfuhl, M. (Co-Investigator), Politis, A. (Co-Investigator), Sanderson, M. (Co-Investigator), Steiner, R. (Co-Investigator), Surman, A. (Co-Investigator) & Sutton, B. (Co-Investigator)
BBSRC Biotechnology and Biological Sciences Research Council
3/11/2021 → 31/10/2022
Project: Research
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Capturing eukaryotic transporters in action
Politis, A. (Primary Investigator)
BBSRC Biotechnology and Biological Sciences Research Council
1/11/2021 → 31/10/2024
Project: Research
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Unravelling the conformational dynamics of membrane proteins within a lipid environment
Politis, A. (Primary Investigator)
1/10/2020 → 30/09/2024
Project: Research