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Arthur Hosie

Dr

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Research interests

Molecular biology of transport proteins in oral bacteria - physiology and pathogenesis.

Research interests (short)

Molecular biology of transport proteins in oral bacteria - physiology and pathogenesis. The aim of Arthur Hosie's research group is to better understand bacterial physiology and pathogenesis by exploiting microbial genome sequence data and molecular techniques. A principal interest is the function and mechanism of action of transport proteins involved in pathogenesis. Such transporters are promising targets for novel antimicrobial strategies - as vaccine components or drug targets. Furthermore, their central role dictates that the results from such investigations will illuminate our understanding of wider aspects of microbial physiology and pathogenesis. Current projects include the characterisation of members of the ABC (ATP binding cassette) transporter superfamily in Streptococcus mutans and Streptococcus pneumoniae, and the characterisation of putative sialic acid transporters in a range of human and animal pathogens. In collaboration with clinical colleagues, we have also initiated a broader investigation of putative virulence factors of Tannerella forsythia, a bacterium associated with periodontal disease.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

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